KEGG   Pan troglodytes (chimpanzee): 740580
Entry
740580            CDS       T01005                                 
Symbol
MGST1
Name
(RefSeq) microsomal glutathione S-transferase 1 isoform X1
  KO
K00799  glutathione S-transferase [EC:2.5.1.18]
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr00480  Glutathione metabolism
ptr00980  Metabolism of xenobiotics by cytochrome P450
ptr00982  Drug metabolism - cytochrome P450
ptr00983  Drug metabolism - other enzymes
ptr01100  Metabolic pathways
ptr01524  Platinum drug resistance
ptr05200  Pathways in cancer
ptr05204  Chemical carcinogenesis - DNA adducts
ptr05207  Chemical carcinogenesis - receptor activation
ptr05208  Chemical carcinogenesis - reactive oxygen species
ptr05225  Hepatocellular carcinoma
ptr05418  Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09100 Metabolism
  09106 Metabolism of other amino acids
   00480 Glutathione metabolism
    740580 (MGST1)
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    740580 (MGST1)
   00982 Drug metabolism - cytochrome P450
    740580 (MGST1)
   00983 Drug metabolism - other enzymes
    740580 (MGST1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    740580 (MGST1)
   05204 Chemical carcinogenesis - DNA adducts
    740580 (MGST1)
   05207 Chemical carcinogenesis - receptor activation
    740580 (MGST1)
   05208 Chemical carcinogenesis - reactive oxygen species
    740580 (MGST1)
  09162 Cancer: specific types
   05225 Hepatocellular carcinoma
    740580 (MGST1)
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    740580 (MGST1)
  09176 Drug resistance: antineoplastic
   01524 Platinum drug resistance
    740580 (MGST1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters [BR:ptr02000]
    740580 (MGST1)
Enzymes [BR:ptr01000]
 2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.18  glutathione transferase
     740580 (MGST1)
Transporters [BR:ptr02000]
 Other transporters
  Pores ion channels [TC:1]
   740580 (MGST1)
SSDB
Motif
Pfam: MAPEG
Other DBs
NCBI-GeneID: 740580
NCBI-ProteinID: XP_009423168
Ensembl: ENSPTRG00000049907
VGNC: 5475
UniProt: H2Q5J7 K7D0X5
LinkDB
Position
10:23478378..23741477
AA seq 155 aa
MVDLTQVMDDEVFMAFASYATIILSKMMLMSTATAFYRLTRKVFANPEDCVAFGKGENAK
KYLRTDDRVERVRRAHLNDLENIIPFLGIGLLYSLSGPDPSTAILHFRLFVGARIYHTIA
YLTPLPQPNRALSFFVGYGVTLSMAYRLLKSKLYL
NT seq 468 nt   +upstreamnt  +downstreamnt
atggttgacctcacccaggtaatggatgatgaagtattcatggcttttgcgtcctatgca
acaattattctttcaaaaatgatgcttatgagtactgcaactgcattctatagattgaca
agaaaggtttttgccaatccagaagactgtgtagcatttggcaaaggagaaaatgccaag
aagtatcttcgaacagatgacagagtagaacgtgtacgcagagcccacctgaatgacctt
gaaaatattattccatttcttggaattggcctcctgtattccttgagtggtcccgacccc
tctacagccatcctgcacttcagactatttgtcggagcacggatctaccacaccattgca
tatttgacaccccttccccagccaaatagagctttgagtttttttgttggatatggagtt
actctttccatggcttacaggttgctgaaaagtaaattgtacctgtaa

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