KEGG   Pan troglodytes (chimpanzee): 741055
Entry
741055            CDS       T01005                                 
Symbol
IGF1
Name
(RefSeq) insulin-like growth factor I isoform X6
  KO
K05459  insulin-like growth factor 1
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr01521  EGFR tyrosine kinase inhibitor resistance
ptr01522  Endocrine resistance
ptr04010  MAPK signaling pathway
ptr04014  Ras signaling pathway
ptr04015  Rap1 signaling pathway
ptr04066  HIF-1 signaling pathway
ptr04068  FoxO signaling pathway
ptr04081  Hormone signaling
ptr04114  Oocyte meiosis
ptr04115  p53 signaling pathway
ptr04150  mTOR signaling pathway
ptr04151  PI3K-Akt signaling pathway
ptr04152  AMPK signaling pathway
ptr04211  Longevity regulating pathway
ptr04213  Longevity regulating pathway - multiple species
ptr04510  Focal adhesion
ptr04550  Signaling pathways regulating pluripotency of stem cells
ptr04730  Long-term depression
ptr04750  Inflammatory mediator regulation of TRP channels
ptr04913  Ovarian steroidogenesis
ptr04914  Progesterone-mediated oocyte maturation
ptr04935  Growth hormone synthesis, secretion and action
ptr04960  Aldosterone-regulated sodium reabsorption
ptr05200  Pathways in cancer
ptr05202  Transcriptional misregulation in cancer
ptr05205  Proteoglycans in cancer
ptr05214  Glioma
ptr05215  Prostate cancer
ptr05218  Melanoma
ptr05224  Breast cancer
ptr05410  Hypertrophic cardiomyopathy
ptr05414  Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    741055 (IGF1)
   04014 Ras signaling pathway
    741055 (IGF1)
   04015 Rap1 signaling pathway
    741055 (IGF1)
   04066 HIF-1 signaling pathway
    741055 (IGF1)
   04068 FoxO signaling pathway
    741055 (IGF1)
   04151 PI3K-Akt signaling pathway
    741055 (IGF1)
   04152 AMPK signaling pathway
    741055 (IGF1)
   04150 mTOR signaling pathway
    741055 (IGF1)
  09133 Signaling molecules and interaction
   04081 Hormone signaling
    741055 (IGF1)
 09140 Cellular Processes
  09143 Cell growth and death
   04114 Oocyte meiosis
    741055 (IGF1)
   04115 p53 signaling pathway
    741055 (IGF1)
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    741055 (IGF1)
   04550 Signaling pathways regulating pluripotency of stem cells
    741055 (IGF1)
 09150 Organismal Systems
  09152 Endocrine system
   04913 Ovarian steroidogenesis
    741055 (IGF1)
   04914 Progesterone-mediated oocyte maturation
    741055 (IGF1)
   04935 Growth hormone synthesis, secretion and action
    741055 (IGF1)
  09155 Excretory system
   04960 Aldosterone-regulated sodium reabsorption
    741055 (IGF1)
  09156 Nervous system
   04730 Long-term depression
    741055 (IGF1)
  09157 Sensory system
   04750 Inflammatory mediator regulation of TRP channels
    741055 (IGF1)
  09149 Aging
   04211 Longevity regulating pathway
    741055 (IGF1)
   04213 Longevity regulating pathway - multiple species
    741055 (IGF1)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    741055 (IGF1)
   05202 Transcriptional misregulation in cancer
    741055 (IGF1)
   05205 Proteoglycans in cancer
    741055 (IGF1)
  09162 Cancer: specific types
   05214 Glioma
    741055 (IGF1)
   05218 Melanoma
    741055 (IGF1)
   05215 Prostate cancer
    741055 (IGF1)
   05224 Breast cancer
    741055 (IGF1)
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    741055 (IGF1)
   05414 Dilated cardiomyopathy
    741055 (IGF1)
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    741055 (IGF1)
   01522 Endocrine resistance
    741055 (IGF1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:ptr04052]
    741055 (IGF1)
Cytokines and neuropeptides [BR:ptr04052]
 Cytokines
  Growth factors (RTK binding)
   741055 (IGF1)
SSDB
Motif
Pfam: Insulin
Other DBs
NCBI-GeneID: 741055
NCBI-ProteinID: XP_001156345
Ensembl: ENSPTRG00000024078
VGNC: 5427
UniProt: A0A663DHR1 A0A2J8N025
LinkDB
Position
10:complement(109223036..109307191)
AA seq 159 aa
MGKISSLPTQLFKCCFCDFLKVKMHTMSSSHLFYLALCLLTFTSSATAGPETLCGAELVD
ALQFVCGDRGFYFNKPTGYGSSSRRAPQTGIVDECCFRSCDLRRLEMYCAPLKPAKSARS
VRAQRHTDMPKTQKYQPPSTNKNTKSQRRRKGSTFEERK
NT seq 480 nt   +upstreamnt  +downstreamnt
atgggaaaaatcagcagtcttccaacccaattatttaagtgctgcttttgtgatttcttg
aaggtgaagatgcacaccatgtcctcctcgcatctcttctacctggcgctgtgcctgctc
accttcaccagctctgccacggctggaccggagacgctctgcggggctgagctggtggat
gctcttcagttcgtgtgtggagacaggggcttttatttcaacaagcccacagggtatggc
tccagcagtcggagggcgcctcagacaggcatcgtggatgagtgctgcttccggagctgt
gatctaaggaggctggagatgtattgcgcacccctcaagcctgccaagtcagctcgctct
gtccgtgcccagcgccacaccgacatgcccaagacccagaagtatcagcccccatctacc
aacaagaacacgaagtctcagaggagaaggaaaggaagtacatttgaagaacgcaagtag

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