Pan troglodytes (chimpanzee): 744289
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Entry
744289 CDS
T01005
Symbol
ULK1
Name
(RefSeq) serine/threonine-protein kinase ULK1 isoform X6
KO
K21357
serine/threonine-protein kinase ULK1 [EC:
2.7.11.1
]
Organism
ptr
Pan troglodytes (chimpanzee)
Pathway
ptr04137
Mitophagy - animal
ptr04140
Autophagy - animal
ptr04150
mTOR signaling pathway
ptr04152
AMPK signaling pathway
ptr04211
Longevity regulating pathway
ptr05010
Alzheimer disease
ptr05014
Amyotrophic lateral sclerosis
ptr05016
Huntington disease
ptr05017
Spinocerebellar ataxia
ptr05022
Pathways of neurodegeneration - multiple diseases
Brite
KEGG Orthology (KO) [BR:
ptr00001
]
09130 Environmental Information Processing
09132 Signal transduction
04152 AMPK signaling pathway
744289 (ULK1)
04150 mTOR signaling pathway
744289 (ULK1)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
744289 (ULK1)
04137 Mitophagy - animal
744289 (ULK1)
09150 Organismal Systems
09149 Aging
04211 Longevity regulating pathway
744289 (ULK1)
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
744289 (ULK1)
05014 Amyotrophic lateral sclerosis
744289 (ULK1)
05016 Huntington disease
744289 (ULK1)
05017 Spinocerebellar ataxia
744289 (ULK1)
05022 Pathways of neurodegeneration - multiple diseases
744289 (ULK1)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
ptr01001
]
744289 (ULK1)
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ptr04131
]
744289 (ULK1)
03029 Mitochondrial biogenesis [BR:
ptr03029
]
744289 (ULK1)
Enzymes [BR:
ptr01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.1 non-specific serine/threonine protein kinase
744289 (ULK1)
Protein kinases [BR:
ptr01001
]
Serine/threonine kinases: Other
ULK family [OT]
744289 (ULK1)
Membrane trafficking [BR:
ptr04131
]
Autophagy
Autophagosome formation proteins
ULK complex
744289 (ULK1)
Mitochondrial biogenesis [BR:
ptr03029
]
Mitochondrial quality control factors
Mitophagy factors
Parkin-independent mechanism factors
744289 (ULK1)
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Pkinase
PK_Tyr_Ser-Thr
ATG1-like_MIT2
ATG1-like_MIT1
Kdo
ABC1
RIO1
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
744289
NCBI-ProteinID:
XP_024203929
LinkDB
All DBs
Position
10:138740308..138769883
Genome browser
AA seq
1060 aa
AA seq
DB search
MEPGRGGTETVGKFEFSRKDLIGHGAFAVVFKGRHREKHDLEVAVKCINKKNLAKSQTLL
GKEIKILKELKHENIVALYDFQEMANSVYLVMEYCNGGDLADYLHAMRTLSEDTIRLFLQ
QIAGAMRLLHSKGIIHRDLKPQNILLSNPAGRRANPNSIRVKIADFGFARYLQSNMMAAT
LCGSPMYMAPEVIMSQHYDGKADLWSIGTIVYQCLTGKAPFQSPVWSPAWSEASSPQDLR
LFYEKNKTLVPTIPRETSAPLRQLLLALLQRNHKDRMDFDEFFHHPFLDASPSVRKSPPV
PVPSYPSSGSGSSSSSSSTSHLASPPSLGEMQQLQKTLASPADTAGFLHSSRDSGGSKDS
SCDTDDFVMVPAQFPGDLVAEAPSAKPPPDSLMCSGSSLVASAGLESHGRTPSPSPPCSS
SPSPSGRAGPFSSSRCGASVPIPVPTQVQNYQRIERNLQSPTQFQTPRSSAIRRSGSTSP
LGFARASPSPPAHAEHGGVLARKMSLGGGRPYTPSPQVGTIPERPGWSGTPSPQGAEMWG
GRSPRPGSSAPEHSTRTSGLGCRLHSAPNLSDLHVVRPKLPKPPTDPLGAVFSPPQASPP
QPSHGLQSCRSLRGSPKLPDFLQRNPLPPILGSPTKAVPSFDFPKTPSSQNLLALLARQG
VVMTPPRNRTLPDLSEVGPFHGQPLGPGLRPGEDPKGPFGRSFSTSRLTDLLLKAAFGTQ
APDPGSTESLQEKPMEIAPSAGFGGSLHPGARAGGTSSPSPVVFTVGSPPSGSTPPQGPR
TRMFSVGPTGSASSSARHLVPGPCSEAPAPELPAPGHGCSFADPIAANLEGAVTFEAPDL
PEETLMEQEHTEILRGLRFTLLFVQHVLEIAALKGSASEAAGGPEYQLQESVVADQISLL
SREWGFAEQLVLYLKVAELLSSGLQTAIDQIRAGKLCLSSTVKQVVRRLNELYKASVVSC
QGLSLRLQRFFLDKQRLLDRIHSITAERLIFSHAVQMVQSAALDEMFQHREGCVPRYHKA
LLLLEGLQHMLSDQADIENVTKCKLCIERRLSALLTGICA
NT seq
3183 nt
NT seq
+upstream
nt +downstream
nt
atggagcccggccgcggcggcacagagaccgtgggcaagttcgagttctcccgcaaggac
ctgatcggccacggcgccttcgcggtggtcttcaagggccgccaccgcgagaagcacgat
ttggaggtcgccgtcaagtgcattaacaagaagaacctcgccaagtctcagacgctgctg
gggaaggaaatcaaaatcctgaaggaactgaaacatgaaaacatcgtggccctgtacgac
ttccaggaaatggctaattctgtctacctggttatggagtactgcaacggtggggacctg
gccgactacctgcacgccatgcgcacgctgagcgaggacaccatcaggctcttcctgcag
cagatcgcgggcgccatgcggcttctgcacagcaaaggcatcatccaccgcgacctgaag
ccgcagaacatcctgctgtccaaccccgccggccgccgcgccaaccccaacagcatccgc
gtcaagatcgctgacttcggcttcgcgcggtacctccagagcaacatgatggcggccaca
ctctgcggctcccccatgtacatggcccccgaggtcatcatgtcccagcactacgacggg
aaggcggacctgtggagcatcggcaccatcgtctaccagtgcctgacggggaaggcgccc
ttccagtcgcctgtctggtcgcctgcctggtcagaggccagcagcccccaggacctgcgc
ctgttctacgagaagaacaagacgttggtccccaccatcccccgggagacctcggccccg
ctgcggcagctgctcctggccctactgcaacgcaaccacaaggaccgcatggacttcgat
gagttttttcatcaccctttcctcgatgccagcccctcggtcaggaaatccccacccgtg
cctgtgccctcgtacccaagctcggggtctggcagcagctccagcagcagctccacctcc
cacctggcctccccgccgtccctgggcgagatgcagcagctgcagaagaccctggcctcc
ccggctgacaccgctggcttcctgcacagctcccgggactctggtggcagcaaggactcc
tcctgtgacacagacgacttcgtcatggtccccgcgcagtttccaggtgacctggtggct
gaggcgcccagtgccaaacccccgccagacagcctgatgtgcagtgggagctcactggtg
gcctctgcgggcttggagagccacggccggaccccatctccatccccaccctgcagcagc
tcccctagtccctcaggccgggctggcccgttctccagcagcaggtgcggcgcctctgtc
cccatcccagtccccacgcaggtgcagaactaccagcgcattgagcgaaacctgcagtca
cccacccagttccaaacacctcggtcctctgccatccgcaggtcaggcagcaccagcccc
ctgggctttgcaagggccagcccctcgccccctgcccacgctgagcatggaggcgtcctg
gccaggaagatgtctctgggtggaggccggccctacacgccatcgcctcaagttggaacc
atccctgagcggccaggctggagcgggacgccctccccacagggagctgagatgtggggt
ggcaggtcccctcgtccaggctcctctgcacccgagcactctacccgcacttccgggctg
ggctgccgcctgcacagcgcccccaacctgtctgacttgcacgtcgtccgccccaagctg
cccaaaccccccacggaccccctgggagctgtgttcagcccaccacaggccagccctccc
cagccgtcccacggcctgcagtcctgccggagcctgcggggctcacccaagctgcccgac
ttcctgcagcgaaaccccctgccccccatcctgggctcccccaccaaggctgtgccctcc
ttcgacttcccgaagacccccagctcccagaacctgctggccctcctagcccggcagggc
gtggtgatgacgccccctcgaaaccggacgctgcccgacctctctgaggtgggacccttc
catggtcagccgttgggccctggcctgcggccaggcgaggaccccaagggcccctttggc
cggtctttcagcaccagccgcctcactgacctgctccttaaggcggcgtttgggacacaa
gccccggacccaggcagcacggagagcctgcaggagaagcccatggagatcgcaccctca
gctggctttggagggagcctgcacccaggagcccgtgctgggggcaccagcagcccctcc
ccggtggtcttcaccgtgggctctcccccgagcgggagcacgcccccccagggcccccgc
accaggatgttctcagtgggccccactggctctgccagctcttctgcccgccacctggtg
cctgggccctgcagcgaggccccagcccctgagctccctgctccaggacacggctgcagc
tttgccgaccccattgctgcgaacctggagggggctgtgaccttcgaggcccccgacctc
cctgaggagaccctcatggagcaagagcacacggagatcctgcgtggcctgcgcttcacg
ctgctgttcgtgcagcacgtcctggagatcgcagccctgaagggcagcgccagtgaggcg
gcggggggccctgagtaccagctgcaggagagtgtggtggccgaccagatcagcctgctg
agccgagaatggggcttcgcagaacagctggtgctgtacctgaaggtggccgagctactg
tcctccggcctgcaaactgccatcgaccagatccgggccggcaagctctgcctgtcgtcc
actgtgaagcaggtggtgcgcaggctgaatgagctgtacaaggccagcgtggtgtcctgc
cagggcctgagcctgcggctgcagcgcttcttcctggacaagcagcggcttctggaccgc
attcacagcatcactgccgagaggctcatcttcagccacgctgtgcagatggtgcagtcg
gctgccctggacgagatgttccagcaccgtgagggctgcgtcccgcgctaccacaaggcc
ctgctgctcctggaggggctgcagcacatgctctcggaccaggccgacatcgagaacgtc
accaagtgcaagctgtgcattgagcggagactctcggcgctgctgactggcatctgtgcc
tga
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