KEGG   Pan troglodytes (chimpanzee): 749769
Entry
749769            CDS       T01005                                 
Symbol
VHL
Name
(RefSeq) von Hippel-Lindau disease tumor suppressor isoform X1
  KO
K03871  von Hippel-Lindau disease tumor supressor
Organism
ptr  Pan troglodytes (chimpanzee)
Pathway
ptr04066  HIF-1 signaling pathway
ptr04120  Ubiquitin mediated proteolysis
ptr05200  Pathways in cancer
ptr05211  Renal cell carcinoma
Brite
KEGG Orthology (KO) [BR:ptr00001]
 09120 Genetic Information Processing
  09123 Folding, sorting and degradation
   04120 Ubiquitin mediated proteolysis
    749769 (VHL)
 09130 Environmental Information Processing
  09132 Signal transduction
   04066 HIF-1 signaling pathway
    749769 (VHL)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    749769 (VHL)
  09162 Cancer: specific types
   05211 Renal cell carcinoma
    749769 (VHL)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system [BR:ptr04121]
    749769 (VHL)
Ubiquitin system [BR:ptr04121]
 Ubiquitin ligases (E3)
  Multi subunit type E3
   Cul2 complex
    Target recognizing subunit
     749769 (VHL)
SSDB
Motif
Pfam: VHL VHL_C Arm_vescicular
Other DBs
NCBI-GeneID: 749769
NCBI-ProteinID: XP_016795936
Ensembl: ENSPTRG00000043259
VGNC: 48915
UniProt: K7BID8 A0A2I3SEM6
LinkDB
Position
2:14161693..14173272
AA seq 213 aa
MPRRAENWDEAEVGAEEAGVEEYGPEEDGGEESGAEESGPEESGPEELGAEEEMEAGRPR
PVLRSVNSREPSQVIFCNRSPRVVLPVWLNFDGEPQPYPTLPPGTGRRIHSYRGHLWLFR
DAGTHDGLLVNQTELFVPSLNVDGQPIFANITLPVYTLKERCLQVVRSLVKPENYRRLDI
VRSLYEDLEDHPNVQKDLERLTQERIAHQRMGD
NT seq 642 nt   +upstreamnt  +downstreamnt
atgccccggagggcggagaactgggacgaggccgaggtaggcgcggaggaggcaggcgtc
gaagagtacggccctgaagaagacggcggggaggagtcgggcgccgaggagtccggcccg
gaagagtccggcccggaggaactgggcgccgaggaggagatggaggccgggcggccgcgg
cccgtgctgcgctcggtgaactcgcgcgagccctcccaggtcatcttctgcaaccgcagt
ccgcgcgtcgtgctgcccgtatggctcaacttcgacggcgagccgcagccctacccaacg
ctgccgcctggcacgggccgccgcatccacagctaccgaggtcacctttggctcttcaga
gatgcagggacacatgatgggcttctggttaaccaaactgaattatttgtgccatctctc
aatgttgacggacagcctatttttgccaatatcacactgccagtgtatactctgaaagag
cgatgcctccaggttgtccggagcctagtcaagcctgagaattacaggagactggacatc
gtcaggtcgctctacgaagatctggaagaccacccaaatgtgcagaaagacctggagcgg
ctgacacaggagcgcattgcacatcaacggatgggagattga

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