Panthera uncia (snow leopard): 125911772 Help Entry 125911772         CDS       T08832                                  Name (RefSeq) caspase-8 isoform X1   KO K04398   caspase 8 [EC:3.4.22.61] Organism puc  Panthera uncia (snow leopard) Pathway puc01524   Platinum drug resistance puc04115   p53 signaling pathway puc04210   Apoptosis puc04215   Apoptosis - multiple species puc04217   Necroptosis puc04620   Toll-like receptor signaling pathway puc04621   NOD-like receptor signaling pathway puc04622   RIG-I-like receptor signaling pathway puc04623   Cytosolic DNA-sensing pathway puc04625   C-type lectin receptor signaling pathway puc04657   IL-17 signaling pathway puc04668   TNF signaling pathway puc04932   Non-alcoholic fatty liver disease puc04936   Alcoholic liver disease puc05010   Alzheimer disease puc05016   Huntington disease puc05022   Pathways of neurodegeneration - multiple diseases puc05132   Salmonella infection puc05134   Legionellosis puc05142   Chagas disease puc05145   Toxoplasmosis puc05152   Tuberculosis puc05160   Hepatitis C puc05161   Hepatitis B puc05162   Measles puc05163   Human cytomegalovirus infection puc05164   Influenza A puc05165   Human papillomavirus infection puc05167   Kaposi sarcoma-associated herpesvirus infection puc05168   Herpes simplex virus 1 infection puc05169   Epstein-Barr virus infection puc05170   Human immunodeficiency virus 1 infection puc05200   Pathways in cancer puc05203   Viral carcinogenesis puc05416   Viral myocarditis puc05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:puc00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     125911772  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     125911772    04215 Apoptosis - multiple species     125911772    04217 Necroptosis     125911772    04115 p53 signaling pathway     125911772  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     125911772    04621 NOD-like receptor signaling pathway     125911772    04622 RIG-I-like receptor signaling pathway     125911772    04623 Cytosolic DNA-sensing pathway     125911772    04625 C-type lectin receptor signaling pathway     125911772    04657 IL-17 signaling pathway     125911772  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125911772    05203 Viral carcinogenesis     125911772   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     125911772    05161 Hepatitis B     125911772    05160 Hepatitis C     125911772    05164 Influenza A     125911772    05162 Measles     125911772    05168 Herpes simplex virus 1 infection     125911772    05163 Human cytomegalovirus infection     125911772    05167 Kaposi sarcoma-associated herpesvirus infection     125911772    05169 Epstein-Barr virus infection     125911772    05165 Human papillomavirus infection     125911772   09171 Infectious disease: bacterial    05132 Salmonella infection     125911772    05134 Legionellosis     125911772    05152 Tuberculosis     125911772   09174 Infectious disease: parasitic    05145 Toxoplasmosis     125911772    05142 Chagas disease     125911772   09164 Neurodegenerative disease    05010 Alzheimer disease     125911772    05016 Huntington disease     125911772    05022 Pathways of neurodegeneration - multiple diseases     125911772   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     125911772    05416 Viral myocarditis     125911772   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     125911772    04932 Non-alcoholic fatty liver disease     125911772   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     125911772  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:puc01002]     125911772 Enzymes [BR:puc01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      125911772 Peptidases and inhibitors [BR:puc01002]  Cysteine peptidases   Family C14: caspase family    125911772 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  125911772 NCBI-ProteinID:  XP_049471843 LinkDB All DBs Position C1 Genome browser AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEAMEQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRMSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTNFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagctgggcagtgatgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctgttcaactacctgaac accagcaaggaagcaatggagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaatgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgcggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacaaacttcgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccccatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactctgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaggctgattttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccctacggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggcgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctactttcacactgaggaaaaaactcttcttccctcttaattga

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