Panthera uncia (snow leopard): 125912825 Help Entry 125912825         CDS       T08832                                  Name (RefSeq) tyrosine-protein kinase Lck   KO K05856   lymphocyte cell-specific protein tyrosine kinase [EC:2.7.10.2] Organism puc  Panthera uncia (snow leopard) Pathway puc04064   NF-kappa B signaling pathway puc04380   Osteoclast differentiation puc04650   Natural killer cell mediated cytotoxicity puc04658   Th1 and Th2 cell differentiation puc04659   Th17 cell differentiation puc04660   T cell receptor signaling pathway puc05135   Yersinia infection puc05166   Human T-cell leukemia virus 1 infection puc05235   PD-L1 expression and PD-1 checkpoint pathway in cancer puc05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:puc00001]  09130 Environmental Information Processing   09132 Signal transduction    04064 NF-kappa B signaling pathway     125912825  09150 Organismal Systems   09151 Immune system    04650 Natural killer cell mediated cytotoxicity     125912825    04660 T cell receptor signaling pathway     125912825    04658 Th1 and Th2 cell differentiation     125912825    04659 Th17 cell differentiation     125912825   09158 Development and regeneration    04380 Osteoclast differentiation     125912825  09160 Human Diseases   09161 Cancer: overview    05235 PD-L1 expression and PD-1 checkpoint pathway in cancer     125912825   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     125912825   09171 Infectious disease: bacterial    05135 Yersinia infection     125912825   09163 Immune disease    05340 Primary immunodeficiency     125912825  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:puc01001]     125912825   09182 Protein families: genetic information processing    03036 Chromosome and associated proteins [BR:puc03036]     125912825 Enzymes [BR:puc01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      125912825 Protein kinases [BR:puc01001]  Non-receptor tyrosine kinases   SRC family    125912825 Chromosome and associated proteins [BR:puc03036]  Eukaryotic type   Centrosome formation proteins    Kinases and associated factors     125912825 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase SH2 SH3_1 SH3_2 SH3_9 ABC1 SH2_1 Haspin_kinase SH3_16 SH3_3 Motif Other DBs NCBI-GeneID:  125912825 NCBI-ProteinID:  XP_049473548 LinkDB All DBs Position C1 Genome browser AA seq 509 aa AA seqDB search MGCSCSSNPEDDWMENIDVCENCHYPIIPLDGKATLPMRNGSDVRDPLVTYEGSNPPASP LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRDFDQNQGEVVKH YKIRNLDKGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKPQKPWWEDEWEV PRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEANLMKQLQHQRL VRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTINKLLDMAAQIAEGMAFIEERNY IHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAPEAINYGTFTIK SDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEELYHLMMLCWKER PEERPTFDYLRSVLEDFFTATEGQYQPQP NT seq 1530 nt NT seq  +upstreamnt  +downstreamnt atgggctgtagctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtgtgc gagaactgccattacccgataatcccactggatggcaaggccacgctgcccatgcggaat ggctctgatgtgagggatccactagttacctacgaaggctccaatcccccagcctcacca ttgcaagacaacctggttatcgctctgcacagctacgagccctctcacgatggagacctg ggcttcgagaagggtgaacagctccgtatcctggagcagagcggcgagtggtggaaggcg cagtccctgaccacaggccaggaaggtttcatccccttcaacttcgtggccaaagcgaac agcctggagcccgaaccctggttcttcaagaacctgagccgcaaggacgcggaacggcag ctcctggcgcccgggaacacgcacggctcctttctgatccgggagagcgagagcaccgcg ggatcgttttcactgtccgtgcgggacttcgaccagaaccagggagaggtggtgaaacat tacaagatccgtaacctggacaaaggcggcttctacatctccccccgcatcacttttcct ggcctgcacgagctggtccgccattacaccaatgcttcggacgggctgtgcacgcggttg agtcgcccctgccagacccagaagccccagaagccttggtgggaggacgagtgggaggtt cccagggagacgctgaagctggtggagcggctgggggctggccagttcggggaggtgtgg atggggtactacaacgggcacacaaaggtggcagtgaagagcctgaagcagggcagcatg tcccccgacgccttcctggccgaggccaacctcatgaagcagctacaacaccagaggctg gtccggctctacgcggtggtcacccaggagcccatctacatcatcacggaatacatggag aatgggagcctggtggatttcctcaagacccctccaggcatcaagttgaccatcaacaaa ctcttggacatggcagcccaaattgcagagggcatggcattcattgaagaacggaattac atccaccgtgacctgagggctgccaacatcctggtgtcggacaccctgagctgcaagatt gcagactttggcctagcgcgcctcattgaggacaatgagtacacagccagggagggggcc aagtttcccattaagtggacagcaccagaagccattaactacgggacattcaccatcaag tcggacgtgtggtcttttgggatcctactgacggagattgtcacccatggccgcatccct tacccagggatgaccaatcctgaggtgattcagaacctggagcgaggctaccgcatggtg cgacctgacaactgcccagaggagctataccacctcatgatgctgtgctggaaggagcgg ccagaggaacggcccacctttgactacctgcgcagtgtgctggaggacttcttcacggcc acagagggccagtaccagccccagccctga

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