KEGG   Panthera uncia (snow leopard): 125915432
Entry
125915432         CDS       T08832                                 
Name
(RefSeq) transforming growth factor beta-1 proprotein isoform X1
  KO
K13375  transforming growth factor beta-1
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc04010  MAPK signaling pathway
puc04060  Cytokine-cytokine receptor interaction
puc04068  FoxO signaling pathway
puc04110  Cell cycle
puc04148  Efferocytosis
puc04218  Cellular senescence
puc04350  TGF-beta signaling pathway
puc04380  Osteoclast differentiation
puc04390  Hippo signaling pathway
puc04659  Th17 cell differentiation
puc04672  Intestinal immune network for IgA production
puc04926  Relaxin signaling pathway
puc04932  Non-alcoholic fatty liver disease
puc04933  AGE-RAGE signaling pathway in diabetic complications
puc05140  Leishmaniasis
puc05142  Chagas disease
puc05144  Malaria
puc05145  Toxoplasmosis
puc05146  Amoebiasis
puc05152  Tuberculosis
puc05161  Hepatitis B
puc05166  Human T-cell leukemia virus 1 infection
puc05200  Pathways in cancer
puc05205  Proteoglycans in cancer
puc05210  Colorectal cancer
puc05211  Renal cell carcinoma
puc05212  Pancreatic cancer
puc05220  Chronic myeloid leukemia
puc05225  Hepatocellular carcinoma
puc05226  Gastric cancer
puc05321  Inflammatory bowel disease
puc05323  Rheumatoid arthritis
puc05410  Hypertrophic cardiomyopathy
puc05414  Dilated cardiomyopathy
puc05415  Diabetic cardiomyopathy
Brite
KEGG Orthology (KO) [BR:puc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125915432
   04350 TGF-beta signaling pathway
    125915432
   04390 Hippo signaling pathway
    125915432
   04068 FoxO signaling pathway
    125915432
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    125915432
 09140 Cellular Processes
  09141 Transport and catabolism
   04148 Efferocytosis
    125915432
  09143 Cell growth and death
   04110 Cell cycle
    125915432
   04218 Cellular senescence
    125915432
 09150 Organismal Systems
  09151 Immune system
   04659 Th17 cell differentiation
    125915432
   04672 Intestinal immune network for IgA production
    125915432
  09152 Endocrine system
   04926 Relaxin signaling pathway
    125915432
  09158 Development and regeneration
   04380 Osteoclast differentiation
    125915432
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125915432
   05205 Proteoglycans in cancer
    125915432
  09162 Cancer: specific types
   05210 Colorectal cancer
    125915432
   05212 Pancreatic cancer
    125915432
   05225 Hepatocellular carcinoma
    125915432
   05226 Gastric cancer
    125915432
   05220 Chronic myeloid leukemia
    125915432
   05211 Renal cell carcinoma
    125915432
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    125915432
   05161 Hepatitis B
    125915432
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    125915432
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    125915432
   05144 Malaria
    125915432
   05145 Toxoplasmosis
    125915432
   05140 Leishmaniasis
    125915432
   05142 Chagas disease
    125915432
  09163 Immune disease
   05323 Rheumatoid arthritis
    125915432
   05321 Inflammatory bowel disease
    125915432
  09166 Cardiovascular disease
   05410 Hypertrophic cardiomyopathy
    125915432
   05414 Dilated cardiomyopathy
    125915432
   05415 Diabetic cardiomyopathy
    125915432
  09167 Endocrine and metabolic disease
   04932 Non-alcoholic fatty liver disease
    125915432
   04933 AGE-RAGE signaling pathway in diabetic complications
    125915432
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03110 Chaperones and folding catalysts [BR:puc03110]
    125915432
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:puc04052]
    125915432
   00536 Glycosaminoglycan binding proteins [BR:puc00536]
    125915432
Chaperones and folding catalysts [BR:puc03110]
 Intramolecular chaperones
  Others
   125915432
Cytokines and neuropeptides [BR:puc04052]
 Cytokines
  Transforming growth factors (RSTK binding)
   125915432
Glycosaminoglycan binding proteins [BR:puc00536]
 Heparan sulfate / Heparin
  Growth factors/receptors
   125915432
SSDB
Motif
Pfam: TGFb_propeptide TGF_beta
Other DBs
NCBI-GeneID: 125915432
NCBI-ProteinID: XP_049477231
LinkDB
Position
E2
AA seq 391 aa
MPPSGLRLLPLLLPLLWLLVLTPGRPAAGLSTCKTIDMELVKRKRIEAIRGQILSKLRLA
SPPSQGEVPPGPLPEAVLALYNSTRDRVAGESAEPEPEPEADYYAKEVTRVLMVENTNKI
YEKVQRTPHSIYMLFNTSELREAVPEPVLLSRAELRLLRLKLKAEQHVELYQKYSNNSWR
YLSNRLLAPSDTPEWLSFDVTGVVRQWLSHGGEVEGFRLSAHCSCDSKDNTLQVDINAGF
SSGRRGDLATIHGMNRPFLLLMATPLERAQHLHSSRHRRALDTNYCFSSTEKNCCVRQLY
IDFRKDLGWKWIHEPKGYHANFCLGPCPYIWSLDTQYSKVLALYNQHNPGASAAPCCVPQ
ALEPLPIVYYVGRKPKVEQLSNMIVRSCKCS
NT seq 1176 nt   +upstreamnt  +downstreamnt
atgccgccctccgggctgcggctgctgccgctgctgctgccgctgctgtggctactagtg
ctgacgcctggccggccggccgccggactgtccacctgcaagaccatcgacatggaactg
gtgaagcggaagcgcatcgaggccatccgcggccagatcctgtccaagctgcggctcgcc
agccccccgagccagggggaggtgccgcccggcccgctgcccgaggctgtgctggccctt
tacaacagtacccgcgaccgggtggcgggggagagcgccgagccggagccggagcctgag
gcggactactacgccaaggaggtcacccgcgtgctaatggtggaaaacaccaacaaaatc
tatgagaaagtccagcgtaccccgcacagcatatatatgctctttaacacgtcggagctc
cgagaagcagtgcccgagcccgtcttgctctcccgggcagagttgcgcctgctgaggctc
aagttaaaggcggagcagcacgtggagctgtaccagaaatacagcaataattcctggcgc
tacctcagcaaccggctgctggcgcccagtgacacgccggaatggctgtcctttgatgtc
actggagtggtgcggcagtggctgagccatggaggggaagtagagggctttcgcctcagt
gcccactgttcctgtgacagcaaagataacacgctgcaagtggacatcaacgcagggttc
agttccggccgccgaggtgacctggccaccattcatggcatgaaccggccttttctgctc
ctcatggccaccccgctggagagggcccagcacctgcacagctcacggcaccgccgagcc
ctggacaccaactactgcttcagctccacggagaagaactgctgcgtgcggcagctctat
attgacttccgcaaggatctgggctggaagtggatccacgagcccaagggctaccacgcc
aacttctgcctagggccctgtccctacatctggagcctggacacgcagtacagcaaggtc
ctggccctgtacaaccagcacaacccgggcgcgtcggcggctccctgctgcgtgccgcag
gcgctggagcccctgcccatcgtgtactacgtgggccgcaagcccaaggtggagcagctg
tccaacatgatcgtgcgctcctgcaagtgcagctga

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