Panthera uncia (snow leopard): 125919219
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Entry
125919219 CDS
T08832
Name
(RefSeq) receptor tyrosine-protein kinase erbB-3
KO
K05084
receptor tyrosine-protein kinase erbB-3 [EC:
2.7.10.1
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc01521
EGFR tyrosine kinase inhibitor resistance
puc04010
MAPK signaling pathway
puc04012
ErbB signaling pathway
puc04020
Calcium signaling pathway
puc04151
PI3K-Akt signaling pathway
puc05205
Proteoglycans in cancer
puc05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125919219
04012 ErbB signaling pathway
125919219
04020 Calcium signaling pathway
125919219
04151 PI3K-Akt signaling pathway
125919219
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
125919219
05205 Proteoglycans in cancer
125919219
09176 Drug resistance: antineoplastic
01521 EGFR tyrosine kinase inhibitor resistance
125919219
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
puc01001
]
125919219
Enzymes [BR:
puc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
125919219
Protein kinases [BR:
puc01001
]
Receptor tyrosine kinases (RTK)
EGFR family [OT]
125919219
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Recep_L_domain
GF_recep_IV
Furin-like
Pkinase
Kinase-like
TM_ErbB1
DUF4381
Motif
Other DBs
NCBI-GeneID:
125919219
NCBI-ProteinID:
XP_049481699
LinkDB
All DBs
Position
B4:80253506..80271277
Genome browser
AA seq
1339 aa
AA seq
DB search
MRANGALQVLGFFLSLARGSEVGNSQAVCPGTLNGLSVTGDAENQYQTLHKLYERCEVVM
GNLEIVLTGHNADLSFLQWIREVTGYVLVAMNEFSTLPLPNLRVVRGTQVYDGKFAIFVM
LNYNTNSSHALRQLRFTQLTEILSGGVYIEKNDKLCHMDTIDWRDIVRDRDAEIVVKDNG
KSCPPCHEACKGRCWGPRLEDCQTLTKTICAPQCNGHCFGPNPNQCCHDECAGGCSGPQD
TDCFACRLFNDSGACVRQCPQPLVYNKLTFQLEPNPHTKYQYGGVCVASCPHNFVVDQTS
CVRACPPDKMEVDKNGLKMCEPCGGLCPKACEGTGSGSRFQTVDSSNIDGFVNCTKILGN
LDFLITGLNGDPWHKIPALDPEKLNVFRTVREITGYLNIQSWPPHMHNFSVFSNLTTIGG
RSLYNRGFSLLIMKNLNITSLGLRSLKEISAGRIYISANRQLCYHHSLNWTRLLRGPPEE
RLDIKHNRPRRDCVAEGKVCDPLCSSGGCWGPGPGQCLSCRNYSRGGVCVTHCNFLNGEP
REFSHEAECFSCHPECQPMEGSATCNGSGSDACAQCAHFRDGPHCVSSCPYGVLGAKGPI
YKYPDSQNECRPCHENCTQGCKGPELQDCLGQTPALISKTHLAMGLTVVVGLAVVFLILG
GTFLYLRGRRIQNKRAMRRYLERGESIEPLDPSEKANKVLARIFKETELRKLKVLGSGVF
GTVHKGVWIPEGESIKIPVCIKVIEDKSGRQSFQDVTDHMLAIGSLDHAHIVRLLGLCPG
SSLQLVTQYLPLGSLLDHVRQHRGALGPQLLLNWGVQIAKGMYYLEEHGMVHRNLAARNV
LLKSPSQVQVADFGVADLLPPDDKQLLHSEAKTPIKWMALESIHFGKYTHQSDVWSYGVT
VWELMTFGAEPYAGLRLAEVPDLLEKGERLAQPQICTIDVYMVMVKCWMIDENIRPTFKE
LANEFTRMARDPPRYLVIKRESGPGIPPGAEPPALTNKELEEVELEPELELDLDLESEED
GLAATLGSALSLPVGTLNRPRGSQSLLSPSSGYMPMNQGNLGEACQESAVCGGGERCPRP
VSLHPLPRGRLASESSEGHVTGSEAELQEKVSMCRSRSRSPRPRGDSAYHSQRHSLLTPV
TPLSPPGLEEEDVNGYVMPDAHLKGTPSSREGTLSSVGLSSVLGTEEEDEDEEYEYMNRR
RRHSPPRPPRPSSLEELGYEYMDVGSDLSASLGSTQSCPLNPVPIMATAGTTPDEDYEYM
NRRHGGGAPGGDYAAMGACPAAEQGYEEMRAFQGPGHHAPHVHCARLKTLRSLEATDSAF
DNPDYWHSRLFPKANAQRT
NT seq
4020 nt
NT seq
+upstream
nt +downstream
nt
atgagggcgaatggggctctgcaggtgctgggcttctttctcagcttggcccggggctcc
gaggtgggcaactcgcaggcagtctgtcccgggactctgaatgggctgagcgtgactggc
gatgccgagaaccagtaccagacgttgcacaagctctacgagaggtgtgaggtggtgatg
gggaaccttgagattgtgctcacaggacacaatgctgatctctccttcctgcagtggatc
cgagaagtgaccggctatgtcctcgtggccatgaatgagttctctacactgccactaccc
aacctccgggtggtgcgggggacccaggtctacgatgggaagtttgccatctttgtcatg
ttgaactataacaccaactctagccatgctctgcgccagctccgctttactcagctcacc
gagattctgtcagggggtgtttatattgagaagaatgataaactttgtcacatggacaca
atcgactggagggacatcgtgagggaccgagatgccgagatagtggtgaaggacaatggc
aagagctgtcccccctgtcatgaggcctgcaaggggcgctgctggggtcctagactggaa
gactgccagacattgaccaagactatctgtgcccctcagtgtaatggtcactgctttggg
cccaaccccaaccagtgctgccatgatgagtgtgcagggggctgctcaggccctcaggat
acagactgctttgcctgtcgactcttcaatgacagtggggcgtgtgtacgccagtgtcca
cagcctcttgtttacaacaagctaactttccagctggaacccaatccccacaccaagtat
cagtatggtggagtttgtgtagccagctgtccccataactttgtggtagatcaaacttct
tgtgtccgggcctgtcctcctgacaagatggaagtagataaaaatggactcaagatgtgt
gaaccttgtggggggctgtgccctaaagcctgtgaggggacgggctccgggagccgcttc
cagactgtggactctagcaacattgatgggtttgtgaactgcaccaagatcctgggcaac
ctggactttcttatcactggcctcaatggcgacccctggcacaagatccctgccctggac
cctgagaagctcaatgtcttccggacagtacgggagatcacaggttacctgaacatccaa
tcctggcctccccacatgcacaacttcagtgtcttttccaacctgacaaccattgggggc
aggagcctctacaaccggggcttctctttgttgatcatgaagaacttgaatataacatcg
ttgggcctccgatctttgaaagaaatcagtgccgggcgtatctacataagcgccaatagg
cagctgtgctaccaccattctctgaactggacccggctgctgcgggggcctccagaagag
agactagacatcaaacataaccggccccgcagagactgcgtggcagagggcaaagtatgt
gatcccctgtgctcctctgggggatgctggggcccaggtcctggtcagtgcctatcctgt
cgaaactacagccgaggcggtgtctgtgtgacccactgcaactttctgaatggggagcct
cgtgagttttcccatgaggctgaatgcttctcctgtcacccggagtgccaacccatggag
ggtagtgccacatgcaatggctcgggctctgatgcatgtgctcagtgtgcccattttcga
gatgggcctcactgtgtgagcagctgcccctatggagtccttggtgccaagggccccatc
tacaagtatccagattctcagaatgaatgtcggccctgccatgagaactgcacccagggg
tgtaagggaccagagctacaagactgtttaggccaaacaccagcactgatcagcaaaacc
catctggcaatgggtttaacagtggtagtaggattggcagtggttttcctgatcctggga
ggcacttttctctatttgcgtgggcgccggattcagaataagagggctatgaggcgctac
ttggaacggggtgagagcatagaacctctggatcccagtgagaaggctaacaaagtcttg
gccagaatcttcaaagaaacagagctgaggaagcttaaagtgcttggctcgggcgtcttt
ggaactgtgcacaaaggagtgtggattcctgagggtgaatcaatcaagattccagtctgc
attaaagtcattgaggataagagtggacggcaaagttttcaagatgtgacagaccacatg
ctggccattggtagcctagaccatgcccacattgtacggctgctgggactgtgcccaggg
tcatctctgcagcttgtcactcagtacttgcctctgggctccctgctggatcacgtgaga
caacaccgtggagcactggggccccagcttctgctcaactggggagtacagattgccaag
ggtatgtactaccttgaggagcatggtatggtgcataggaacttggctgcccgaaatgtg
ctactgaagtcacccagtcaggttcaggtggcagattttggggtggcggacctgctgccc
cctgacgataagcagctactacacagtgaggccaagactccaattaagtggatggccctc
gagagtatccattttgggaaatacacacaccagagtgacgtctggagctatggagtgaca
gtttgggagctgatgacctttggggcagagccctatgctgggctacgactggctgaagta
cctgacctgctagagaagggggagcgattggcgcagcctcagatctgtaccattgatgtg
tacatggtcatggtcaagtgttggatgattgatgagaatattcgcccaacctttaaagaa
ctagccaatgagtttaccaggatggcccgagacccaccacggtatctggtcataaagaga
gaaagtgggcctggaataccccctggggcagaaccccctgctctgacaaacaaggaactg
gaggaagtggagctggagccagaacttgagctggacctggacttggaatcagaggaggat
ggcctggcagccacactaggctctgctctcagcctgccagttggaacacttaatcggccc
cgtgggagccagagccttttaagcccatcatctggctatatgcctatgaaccagggtaat
cttggggaggcctgccaggagtctgcggtctgtgggggtggtgagcggtgtccccgtcca
gtctccctgcacccactgccacggggacgcctggcatcagagtcttcagaaggccatgtg
acaggctctgaggctgagctccaggagaaggtgtcaatgtgtaggagccggagccggagc
ccacggccacgtggagacagtgcctaccattcccagcgccacagcctgctcactcctgtc
accccactctccccaccaggattagaggaagaggatgtcaatggatatgtcatgccagat
gcacacctcaaaggtactccctcctcccgggagggcaccctttcttcagtgggcctcagt
tctgtcctgggtactgaagaagaagatgaagatgaggaatatgaatacatgaaccggaga
agaaggcacagtccgcctcgtccccctaggcctagctctcttgaggagctgggttatgag
tacatggatgtgggatcagacctcagcgcttccctgggcagcacacagagttgcccactc
aaccctgtgccaatcatggccactgctggcacaaccccggatgaggactatgaatatatg
aatcggcgacatggtgggggagctcctgggggagattatgcagctatgggggcctgccca
gcagctgaacaagggtatgaagagatgagagctttccaggggcctggacaccatgccccc
catgtccactgtgcccgcctcaaaactctacgtagtttagaagccactgactctgctttt
gataaccctgattactggcacagcaggcttttccccaaggctaatgctcagagaacataa
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integrated database retrieval system
