Panthera uncia (snow leopard): 125924401 Help Entry 125924401         CDS       T08832                                  Name (RefSeq) adenylate cyclase type 8   KO K08048   adenylate cyclase 8 [EC:4.6.1.1] Organism puc  Panthera uncia (snow leopard) Pathway puc00230   Purine metabolism puc01100   Metabolic pathways puc01522   Endocrine resistance puc04015   Rap1 signaling pathway puc04020   Calcium signaling pathway puc04022   cGMP-PKG signaling pathway puc04024   cAMP signaling pathway puc04062   Chemokine signaling pathway puc04072   Phospholipase D signaling pathway puc04081   Hormone signaling puc04082   Neuroactive ligand signaling puc04114   Oocyte meiosis puc04211   Longevity regulating pathway puc04213   Longevity regulating pathway - multiple species puc04261   Adrenergic signaling in cardiomyocytes puc04270   Vascular smooth muscle contraction puc04371   Apelin signaling pathway puc04540   Gap junction puc04611   Platelet activation puc04713   Circadian entrainment puc04714   Thermogenesis puc04720   Long-term potentiation puc04723   Retrograde endocannabinoid signaling puc04724   Glutamatergic synapse puc04725   Cholinergic synapse puc04727   GABAergic synapse puc04742   Taste transduction puc04750   Inflammatory mediator regulation of TRP channels puc04911   Insulin secretion puc04912   GnRH signaling pathway puc04913   Ovarian steroidogenesis puc04914   Progesterone-mediated oocyte maturation puc04915   Estrogen signaling pathway puc04916   Melanogenesis puc04918   Thyroid hormone synthesis puc04921   Oxytocin signaling pathway puc04923   Regulation of lipolysis in adipocytes puc04925   Aldosterone synthesis and secretion puc04926   Relaxin signaling pathway puc04927   Cortisol synthesis and secretion puc04928   Parathyroid hormone synthesis, secretion and action puc04934   Cushing syndrome puc04935   Growth hormone synthesis, secretion and action puc04970   Salivary secretion puc04971   Gastric acid secretion puc04972   Pancreatic secretion puc04976   Bile secretion puc05032   Morphine addiction puc05163   Human cytomegalovirus infection puc05166   Human T-cell leukemia virus 1 infection puc05200   Pathways in cancer puc05207   Chemical carcinogenesis - receptor activation puc05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:puc00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     125924401  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     125924401    04371 Apelin signaling pathway     125924401    04020 Calcium signaling pathway     125924401    04072 Phospholipase D signaling pathway     125924401    04024 cAMP signaling pathway     125924401    04022 cGMP-PKG signaling pathway     125924401   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     125924401    04081 Hormone signaling     125924401  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     125924401   09144 Cellular community - eukaryotes    04540 Gap junction     125924401  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     125924401    04062 Chemokine signaling pathway     125924401   09152 Endocrine system    04911 Insulin secretion     125924401    04923 Regulation of lipolysis in adipocytes     125924401    04912 GnRH signaling pathway     125924401    04913 Ovarian steroidogenesis     125924401    04915 Estrogen signaling pathway     125924401    04914 Progesterone-mediated oocyte maturation     125924401    04921 Oxytocin signaling pathway     125924401    04926 Relaxin signaling pathway     125924401    04935 Growth hormone synthesis, secretion and action     125924401    04918 Thyroid hormone synthesis     125924401    04928 Parathyroid hormone synthesis, secretion and action     125924401    04916 Melanogenesis     125924401    04925 Aldosterone synthesis and secretion     125924401    04927 Cortisol synthesis and secretion     125924401   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     125924401    04270 Vascular smooth muscle contraction     125924401   09154 Digestive system    04970 Salivary secretion     125924401    04971 Gastric acid secretion     125924401    04972 Pancreatic secretion     125924401    04976 Bile secretion     125924401   09156 Nervous system    04724 Glutamatergic synapse     125924401    04727 GABAergic synapse     125924401    04725 Cholinergic synapse     125924401    04720 Long-term potentiation     125924401    04723 Retrograde endocannabinoid signaling     125924401   09157 Sensory system    04742 Taste transduction     125924401    04750 Inflammatory mediator regulation of TRP channels     125924401   09149 Aging    04211 Longevity regulating pathway     125924401    04213 Longevity regulating pathway - multiple species     125924401   09159 Environmental adaptation    04713 Circadian entrainment     125924401    04714 Thermogenesis     125924401  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125924401    05207 Chemical carcinogenesis - receptor activation     125924401   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     125924401    05163 Human cytomegalovirus infection     125924401   09165 Substance dependence    05032 Morphine addiction     125924401   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     125924401   09167 Endocrine and metabolic disease    04934 Cushing syndrome     125924401   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     125924401 Enzymes [BR:puc01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      125924401 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc Adcy_cons_dom Motif Other DBs NCBI-GeneID:  125924401 NCBI-ProteinID:  XP_049488864 LinkDB All DBs Position F2:10528405..10655306 Genome browser AA seq 814 aa AA seqDB search MLNELFARFDRLAHEHHCLRIKILGDCYYCVSGLPEPRQDHAHCCVEMGLSMIKTIRYVR SRTKHDVDMRIGIHSGSVLCGVLGLRKWQFDVWSWDVDIANKLESGGIPGRIHISKATLD CLNGDYNVEEGHGKERNEFLRKHNIETYLIKQPEESLLTLPEDIVKESVSFSDRRNSGAT FTEGSWSPELPFDNIVGKQNTLAALTRNSINLLPNHLAQALHVQSGPEEINKRIEHTIDL RSGDKLRREHIKPFSLMFKDSSLEHKYSQMRDEVFKSNLVCAFIVLLFITAIQSLLPSSR VMPMAIQFSILIMLHSALVLITTAEDYKCLPLVLRKTCCWINETYLARNVIIFASILINF LGAILNILWCDFDKSIPLKNLTFNSSAVFTDICSCPEYFVFTGVLAMVTCAVFLRLNSVL KLAVLLIMIAIYALLTETVYAGLFLRYDNLNHSGEDFLGTKEASLLLMAMFLLAVFYHGQ QLEYTARLDFLWRVQAKEEINEMKELREHNENMLRNILPSHVARHFLEKDRDNEELYSQS YDAVGVMFASIPGFADFYSQTEMNNQGVECLRLLNEIIADFDELLGEDRFQDIEKIKTIG STYMAVSGLSPEKQQCEDKWGHLCALADFSLALTESIQEINKHSFNNFELRIGISHGSVV AGVIGAKKPQYDIWGKTVNLASRMDSTGVSGRIQVPEETYLILKDQGFAFDYRGEIYVKG ISEQEGKIKTYFLLGRVQPNPFILPPRRLPGQYSLAAVVLGLVQSLNRQRQKQLLNENIN TGIIKGHYNRRTLLTASGPEPGAQAEGADKSDLP NT seq 2445 nt NT seq  +upstreamnt  +downstreamnt atgctcaacgagctctttgccagatttgatcgactggcccacgagcatcactgccttcgc attaaaatcctgggggactgttactactgtgtttcagggcttccagagccccgccaggac cacgcccactgctgcgttgaaatgggcctcagcatgatcaaaaccatcaggtatgtgagg tcaaggacgaagcatgatgttgacatgcggatcggaatccactcgggctcggtgctgtgt ggcgtgttgggtctgaggaagtggcagtttgatgtctggtcttgggacgtggacatcgcg aacaaacttgagtctggaggaatccctgggaggattcacatttccaaagccacgctggac tgcctcaacggtgactataatgtggaagagggtcatggtaaagagagaaacgaattcttg aggaagcataacatagagacctatttgattaagcagcctgaggagagcctactgacgttg cccgaagacattgtcaaggagtcggtgagcttctcagacaggagaaacagtggggcgaca ttcacagaaggatcctggagccccgaactgccctttgataacatagtggggaaacagaac actctggctgccctaacaagaaattcaataaatctacttccaaaccatcttgcacaagct ttgcatgtccagtctgggcctgaggaaattaacaagagaatagaacataccatcgacttg cggagtggcgataaattgagaagagagcatatcaagccattctcactgatgtttaaagac tccagcctggagcacaagtattctcaaatgagggatgaagtattcaagtcaaacttggtc tgtgcatttatcgttctcctatttatcacggcaatacaaagtttgcttccttcttcaagg gtgatgccaatggccatccagttttccatcctgatcatgctgcactcggctctggtcctc atcaccacggcagaagattacaagtgtttgcctctcgtcctccggaaaacttgctgttgg attaacgagacctacttagcccggaacgtcatcatctttgcatccatcttgattaacttc ctgggcgccatcttgaatatcctgtggtgtgattttgacaagtcgatacccttgaagaac ctgactttcaattcctcagctgtgtttacagatatctgctcctgcccagagtacttcgtc ttcactggggtgttggccatggtgacctgtgcggttttcctccgcctgaactctgtcctg aagctggccgtgctgctgattatgattgccatctacgcgctgctgactgagaccgtctac gcgggcctcttcctgcgctatgacaacctaaaccacagcggagaagatttcctggggacc aaggaggcgtcactgctgctgatggccatgttcctccttgccgtgttctaccacggacag cagctggagtacacggcccgcctggacttcctttggcgagtgcaggccaaagaggagatc aacgagatgaaggagctcagggagcacaatgagaacatgctccggaacattctacccagc cacgtggcccgccacttcctggagaaagaccgagacaacgaggagctgtattcccaatct tatgatgccgtcggggtgatgttcgcctccatcccggggtttgcagacttttactctcag actgagatgaataaccagggggtagaatgcctgcgtctgttgaatgagatcattgctgac ttcgatgagctgctaggcgaagaccggtttcaggacattgaaaagattaagaccatcggc agcacctacatggccgtgtcgggcctgtcacctgaaaaacagcaatgtgaagacaagtgg ggacatctgtgtgccctggccgacttctccctcgccctgaccgaaagcatacaggagatc aacaaacattccttcaacaatttcgaactccggattggcatcagtcacggctccgtggta gctggggtcatcggcgctaagaagccacaatatgacatttggggcaaaactgtgaacctg gcgagccgaatggacagcacaggggtcagcggcaggatccaagtccccgaggagacctat ctcatcctgaaggaccagggctttgccttcgactaccgaggggagatctacgtgaagggc atcagtgagcaggaaggaaaaatcaaaacgtactttctcctgggaagagtccaacccaac ccgttcatcctgcccccgagaagactgcccgggcagtactcactggccgcggtcgtcctg ggccttgtccagtccctcaacaggcaaaggcagaagcagttgctcaatgagaacatcaac acagggatcatcaagggccactacaaccggcggactttgctgacagccagtgggccagag cccggggcccaggctgagggcgccgacaagtccgacttgccatga

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