KEGG   Panthera uncia (snow leopard): 125926671
Entry
125926671         CDS       T08832                                 
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 3 isoform X1
  KO
K04421  mitogen-activated protein kinase kinase kinase 3 [EC:2.7.11.25]
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc04010  MAPK signaling pathway
puc04722  Neurotrophin signaling pathway
puc04912  GnRH signaling pathway
puc05166  Human T-cell leukemia virus 1 infection
puc05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:puc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04010 MAPK signaling pathway
    125926671
 09150 Organismal Systems
  09152 Endocrine system
   04912 GnRH signaling pathway
    125926671
  09156 Nervous system
   04722 Neurotrophin signaling pathway
    125926671
 09160 Human Diseases
  09161 Cancer: overview
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    125926671
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    125926671
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:puc01001]
    125926671
Enzymes [BR:puc01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.25  mitogen-activated protein kinase kinase kinase
     125926671
Protein kinases [BR:puc01001]
 Serine/threonine kinases: STE group
  STE11 family
   125926671
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr PB1 ABC1 Kinase-like FTA2
Other DBs
NCBI-GeneID: 125926671
NCBI-ProteinID: XP_049492290
LinkDB
Position
E1:16656409..16719550
AA seq 635 aa
MDEQEALNSIMKDLVALQMSRRHRVPGYETMKSKDTGHPNRQSDVRIKFEHNGERRIIAF
SRPVRYEDVEHKVTTVFGQPLDLHYMNNEDLRTTCEKSLSILLKNQDDLDKAIDILDRSS
SMKSLRILLLSQDRNHTSPSPHSGVSRQVRIKASQSAGDINTIYQPPEPRSRHLSVSSQN
PGRSSPPPGYVPERQQRIARQGSYTSINSEGEFIPETSEQCMLDPLSSAENSLSGSCQSL
DRSADSPSFRKSRMSRAQSFPDNRQEFSDRETQLYDKGVKGGTYPRRYHVSVHHKDYNEG
RRTFPRIRRHQGNLFTLVPSSRSLSTNGENMGLAVQYLDPRGRLRSADSENALSVQERNV
PTKSPSAPINWRRGKLLGQGAFGRVYLCYDVDTGRELASKQVQFDPDSPETSKEVSALEC
EIQLLKNLQHERIVQYYGCLRDRAEKTLTIFMEYMPGGSVKDQLKAYGALTESVTRKYTR
QILEGMSYLHSNMIVHRDIKGANILRDSAGNVKLGDFGASKRLQTICMSGTGMRSVTGTP
YWMSPEVISGEGYGRKADVWSLGCTVVEMLTEKPPWAEYEAMAAIFKIATQPTNPQLPSH
ISEHGRDFLRRIFVEARQRPSAEELLTHHFAQLVY
NT seq 1908 nt   +upstreamnt  +downstreamnt
atggacgaacaggaggcattgaactcaatcatgaaggatctggtggccctccagatgagc
cgacgtcaccgggtgcctggatatgagaccatgaagagcaaagacacgggtcacccaaat
aggcagagtgacgtcagaatcaagtttgagcacaacggggaaaggcgaattatagcattc
agccggcctgttagatatgaagatgtggaacacaaggtgacaacagtgtttgggcagcct
cttgatcttcattacatgaataatgaggatttgagaaccacatgtgagaaatcgctttcc
atcctgctgaagaaccaagatgatcttgataaagcaattgacatattagacagaagctca
agcatgaaaagccttaggatattgctgctgtcccaagacagaaatcataccagtccctct
ccccattctggggtgtccaggcaggtgcggatcaaagcttcccagtctgcaggagatata
aataccatctaccagccccccgagcccagaagcaggcacctctctgtcagctcccagaac
cctggacgaagctcacctccccctggctatgtgcctgagcggcagcagcgcattgcccgg
caggggtcctataccagcatcaacagcgagggggagttcatcccagagaccagtgagcag
tgtatgttggatcctctgagcagtgctgaaaattccttgtcaggaagctgccaatccttg
gacaggtcagccgacagcccatccttccggaaatcgaggatgtcccgagcccagagcttc
cccgacaacagacaggagttctctgatcgggaaactcagctgtatgacaaaggggtcaaa
ggtggaacctacccccggcgctaccacgtatctgtgcaccacaaggactacaatgagggc
agaagaacatttccccgaatacggcgtcatcaaggcaacctctttacactggtgccatcc
agccgttccctgagcacaaatggcgagaacatgggtttggcagtgcagtacctggacccc
agagggcgcctgcggagcgcggacagcgagaatgccctctctgtgcaggagaggaacgtg
cctaccaagtctcctagtgcccccatcaattggcgccgtgggaagctcctgggccagggt
gccttcggcagggtctatttgtgctatgacgtggacacaggacgtgaacttgcttccaaa
caggtccaatttgacccagacagccctgagacaagcaaggaggtgagtgccctggagtgt
gagatccagctgctgaagaacctgcagcacgagcgcatagttcagtactatggctgcctg
cgggaccgcgccgagaagactctgaccatcttcatggagtacatgccagggggctcagtg
aaagaccaattgaaggcctacggagctctgacagagagtgtgactcgcaagtatacccgg
cagatcctggagggcatgtcctacctgcatagcaacatgatcgttcaccgagacatcaag
ggagccaacatcctccgagactctgccgggaacgtgaagctgggggactttggggccagc
aagcgcctgcagaccatctgcatgtcgggcacgggcatgcgctcggtcacgggcacaccc
tactggatgagccctgaggtgatcagcggtgagggctacggaaggaaggcagacgtgtgg
agcctgggctgcactgtggtagagatgctgacagagaaaccaccttgggcagagtatgaa
gccatggccgccattttcaagattgccacccagcccacaaatcctcagctgccctcccac
atctctgagcacggccgggacttcctgaggcgtatttttgtggaggctcgccagagacct
tcggccgaggagctgctcacacaccactttgcacagctcgtgtactga

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