KEGG   Panthera uncia (snow leopard): 125930836
Entry
125930836         CDS       T08832                                 
Name
(RefSeq) interleukin-6
  KO
K05405  interleukin 6
Organism
puc  Panthera uncia (snow leopard)
Pathway
puc01521  EGFR tyrosine kinase inhibitor resistance
puc01523  Antifolate resistance
puc04060  Cytokine-cytokine receptor interaction
puc04061  Viral protein interaction with cytokine and cytokine receptor
puc04066  HIF-1 signaling pathway
puc04068  FoxO signaling pathway
puc04151  PI3K-Akt signaling pathway
puc04218  Cellular senescence
puc04620  Toll-like receptor signaling pathway
puc04621  NOD-like receptor signaling pathway
puc04623  Cytosolic DNA-sensing pathway
puc04625  C-type lectin receptor signaling pathway
puc04630  JAK-STAT signaling pathway
puc04640  Hematopoietic cell lineage
puc04657  IL-17 signaling pathway
puc04659  Th17 cell differentiation
puc04668  TNF signaling pathway
puc04672  Intestinal immune network for IgA production
puc04931  Insulin resistance
puc04932  Non-alcoholic fatty liver disease
puc04933  AGE-RAGE signaling pathway in diabetic complications
puc04936  Alcoholic liver disease
puc05010  Alzheimer disease
puc05020  Prion disease
puc05022  Pathways of neurodegeneration - multiple diseases
puc05132  Salmonella infection
puc05133  Pertussis
puc05134  Legionellosis
puc05135  Yersinia infection
puc05142  Chagas disease
puc05143  African trypanosomiasis
puc05144  Malaria
puc05146  Amoebiasis
puc05152  Tuberculosis
puc05161  Hepatitis B
puc05162  Measles
puc05163  Human cytomegalovirus infection
puc05164  Influenza A
puc05166  Human T-cell leukemia virus 1 infection
puc05167  Kaposi sarcoma-associated herpesvirus infection
puc05168  Herpes simplex virus 1 infection
puc05169  Epstein-Barr virus infection
puc05171  Coronavirus disease - COVID-19
puc05200  Pathways in cancer
puc05202  Transcriptional misregulation in cancer
puc05321  Inflammatory bowel disease
puc05323  Rheumatoid arthritis
puc05332  Graft-versus-host disease
puc05410  Hypertrophic cardiomyopathy
puc05417  Lipid and atherosclerosis
Brite
KEGG Orthology (KO) [BR:puc00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    125930836
   04668 TNF signaling pathway
    125930836
   04066 HIF-1 signaling pathway
    125930836
   04068 FoxO signaling pathway
    125930836
   04151 PI3K-Akt signaling pathway
    125930836
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    125930836
   04061 Viral protein interaction with cytokine and cytokine receptor
    125930836
 09140 Cellular Processes
  09143 Cell growth and death
   04218 Cellular senescence
    125930836
 09150 Organismal Systems
  09151 Immune system
   04640 Hematopoietic cell lineage
    125930836
   04620 Toll-like receptor signaling pathway
    125930836
   04621 NOD-like receptor signaling pathway
    125930836
   04623 Cytosolic DNA-sensing pathway
    125930836
   04625 C-type lectin receptor signaling pathway
    125930836
   04659 Th17 cell differentiation
    125930836
   04657 IL-17 signaling pathway
    125930836
   04672 Intestinal immune network for IgA production
    125930836
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    125930836
   05202 Transcriptional misregulation in cancer
    125930836
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    125930836
   05161 Hepatitis B
    125930836
   05171 Coronavirus disease - COVID-19
    125930836
   05164 Influenza A
    125930836
   05162 Measles
    125930836
   05168 Herpes simplex virus 1 infection
    125930836
   05163 Human cytomegalovirus infection
    125930836
   05167 Kaposi sarcoma-associated herpesvirus infection
    125930836
   05169 Epstein-Barr virus infection
    125930836
  09171 Infectious disease: bacterial
   05132 Salmonella infection
    125930836
   05135 Yersinia infection
    125930836
   05133 Pertussis
    125930836
   05134 Legionellosis
    125930836
   05152 Tuberculosis
    125930836
  09174 Infectious disease: parasitic
   05146 Amoebiasis
    125930836
   05144 Malaria
    125930836
   05142 Chagas disease
    125930836
   05143 African trypanosomiasis
    125930836
  09163 Immune disease
   05323 Rheumatoid arthritis
    125930836
   05321 Inflammatory bowel disease
    125930836
   05332 Graft-versus-host disease
    125930836
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    125930836
   05020 Prion disease
    125930836
   05022 Pathways of neurodegeneration - multiple diseases
    125930836
  09166 Cardiovascular disease
   05417 Lipid and atherosclerosis
    125930836
   05410 Hypertrophic cardiomyopathy
    125930836
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    125930836
   04932 Non-alcoholic fatty liver disease
    125930836
   04931 Insulin resistance
    125930836
   04933 AGE-RAGE signaling pathway in diabetic complications
    125930836
  09176 Drug resistance: antineoplastic
   01521 EGFR tyrosine kinase inhibitor resistance
    125930836
   01523 Antifolate resistance
    125930836
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04052 Cytokines and neuropeptides [BR:puc04052]
    125930836
Cytokines and neuropeptides [BR:puc04052]
 Cytokines
  Interleukins
   125930836
SSDB
Motif
Pfam: IL6 GCSF Sec16 DUF4924 IL23
Other DBs
NCBI-GeneID: 125930836
NCBI-ProteinID: XP_049498869
LinkDB
Position
A2:110438712..110442980
AA seq 233 aa
MSEAHSALEPTRNERELHLPSRTPAMTFLSTSAFSPLAFSLGLLLVVATAFPTPGPLGGD
ATSNRLPLTSADKMEELIKYILGKISALKKEMCDNYNKCEDSKEALAENNLNLPKLAEKD
GCFQSGFNQETCLTRITTGLQEFQIYLKFLQDKYEGDKENAKSVYTNTNVLLQMLKRKGK
NQDEVTIPVPTVEVGLQAKLQSQEEWLRHTTIHLTLRRLEDFLQFSLRAVRIM
NT seq 702 nt   +upstreamnt  +downstreamnt
atgtctgaggctcattctgccctcgagcccaccaggaacgaaagagagctccatctgccc
tccaggactccagccatgaccttcctctccacaagcgccttcagtccactcgccttctcc
ctggggctgctcctggtggtggctactgctttccctaccccgggacccctgggaggagat
gccacctcaaatagactaccactcacctctgcagacaaaatggaagaactcattaagtac
atcctcggcaaaatctctgcactgaaaaaggagatgtgtgacaactataacaaatgtgag
gacagcaaggaggcactggcagaaaacaacctaaatcttccgaaactggcagaaaaagat
ggatgcttccaatctgggttcaatcaggagacctgcctgacaagaatcactactggtctt
caggagtttcagatatacctgaaattcctccaggacaagtatgagggtgataaggaaaat
gccaagtctgtatacaccaatactaacgtcctgctccagatgctgaagcgtaagggaaag
aatcaggatgaggtaaccatccctgtcccaaccgtagaagttggcctgcaggctaagctg
cagtcacaggaagagtggctgaggcacacaacaattcacctcaccctgcgaaggctggag
gacttccttcagttcagcctcagggctgttcggataatgtaa

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