Panthera uncia (snow leopard): 125933341
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Entry
125933341 CDS
T08832
Name
(RefSeq) proto-oncogene tyrosine-protein kinase receptor Ret isoform X1
KO
K05126
proto-oncogene tyrosine-protein kinase Ret [EC:
2.7.10.1
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc04010
MAPK signaling pathway
puc04020
Calcium signaling pathway
puc04151
PI3K-Akt signaling pathway
puc05200
Pathways in cancer
puc05216
Thyroid cancer
puc05223
Non-small cell lung cancer
puc05230
Central carbon metabolism in cancer
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125933341
04020 Calcium signaling pathway
125933341
04151 PI3K-Akt signaling pathway
125933341
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
125933341
05230 Central carbon metabolism in cancer
125933341
09162 Cancer: specific types
05216 Thyroid cancer
125933341
05223 Non-small cell lung cancer
125933341
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
puc01001
]
125933341
Enzymes [BR:
puc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.1 receptor protein-tyrosine kinase
125933341
Protein kinases [BR:
puc01001
]
Receptor tyrosine kinases (RTK)
RET family
125933341
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
RET_CLD1
RET_CLD4
RET_CLD3
Pkinase
RET_CRD
Cadherin
RIO1
Pkinase_fungal
Haspin_kinase
Motif
Other DBs
NCBI-GeneID:
125933341
NCBI-ProteinID:
XP_049502279
LinkDB
All DBs
Position
D2:complement(48031240..48081953)
Genome browser
AA seq
1119 aa
AA seq
DB search
MLVCLGGLLWTSSSPLPPSHTSLPSPAPLGLYFARDAYWEKLYVDQPAGMPLLYVHALRD
MPEEVPTFRLGQHLYGIAYRARLHENDWIRIEEDTGLLYLNRSLDHSTWDKLSIRNGGFP
VLTIYLQVFLSPTSLREGECQWPGCARVYFSFVNTSFPACGSLKPRELCFPESGVSFRIR
ENRPPGTFHQFRLLPVQFLCPNISVTYRLLEGENLPFHCAPDSLEVSTRWPLDRELREKY
ELVAACMVRVGARKEEVVMVPFPVTVYDEDDSAPTFLGGIDTASAVVEFKRKEGTVVAKI
RVFDADVVPASGELLKRYTNTLLSGDAWVLQTFRIEHSPNETLAQANGSFVRATVHDYRL
VLNRSLPISENRSLQLTVLVNDSDFQGPGEGTLFLHFNVSVLPVSLHLPSTYTFTVSRRA
RRFAQIGKVCVENCQEFSGIHVQYRLQLSSTNCSVLGVVTSAEDTTGNLFVNHTEALQRP
DCSQLRYTVVAADRPTRKQTQALLVVTVEGTYVAEEPGCPLSCAVSKRRPECEECGGLGS
LTGRCEWRQGDGKGITRNFSTCSPSIKTCPDGHCDAVESRNVNICPQDCLRGGSIIGGHE
PGERWGIKAGFGICNCFPEEKKCFCEPEDSQEPLCDELCRTVIAAAVLFSFVVSMLLSTF
CIHRYHKNAHKPPIASAEMTFRRPAQAFPVSYSSSGARRPSMDSMENQVSVDAFKIPEDP
KWEFPRKNLVLGKTLGEGEFGKVVKATAFRLKGKAGYTTVAVKMLKENASPSELRDLLSE
FNLLKQVNHPHVIKLYGACSQDGPLFLIVEYAKYGSLRGFLRESRKAGPGYVGSGGSRSS
SYLDNPEERALTMGDLISFAWQISRGMRYLAEMKLVHRDLAARNVLVAEGRKMKISDFGL
SRDVYEEDSYVKRSKGRIPVKWMAIESLFDHIYTTQSDVWSFGVLLWEIVTLGGNPYPGI
PPERLFNLLKTGYRMERPDNCSEEMYGLMLQCWKQEPDKRPVFADISKDLEKMMVKNRDY
LDLAASTPSDSLLYDDGLSEEETPLVDCNNAPLPRALPSTWIENKLYGMSDPNWPEESPV
PLTRADGTNTVCPRYANDSVYANWMVSPSAAQLMDAFDS
NT seq
3360 nt
NT seq
+upstream
nt +downstream
nt
atgctggtctgcctggggggcttgctctggacatcatcctcacccctccctccctcacac
acttccctcccttctccagctccgctgggactctacttcgccagggatgcttactgggag
aaactctacgtggaccagccagccggcatgcccctgctctacgtccatgccctgcgggac
atgccggaggaggtgcccaccttccgcctgggccagcacctctacggcatcgcctaccgt
gcaaggctgcatgagaacgactggattcgcatcgaggaggacactggccttctctacctt
aaccggagcctggatcacagcacctgggacaagctcagcatccgcaatggcggcttccct
gtgctcaccatctacctccaggtcttcctgtcacctacatccctgcgtgagggcgagtgc
caatggcccggctgtgcccgtgtgtacttctcctttgtcaacacctccttcccggcttgt
ggttccctcaaaccccgggagctctgctttcctgagtcaggtgtctccttccgcatcaga
gagaataggcctcccggcactttccaccagttccgcctgctgcctgtgcagttcctctgc
cccaacatcagcgtgacctacaggctcctagaaggtgagaacctgcccttccactgcgcc
ccggacagcctggaggtgagcacgcgctggcccctggatcgcgagctgcgggagaagtac
gagctggtggctgcttgcatggtgcgcgtcggcgcacgcaaggaggaggtggtgatggtg
cccttccccgtgaccgtgtatgatgaggacgactcggcgcccaccttcctcgggggcatc
gacaccgccagcgctgtggtggagttcaagaggaaggagggcactgtggtggccaaaata
cgtgtcttcgatgcagacgtggtgccagcatccggggagctcctgaagcgatacacaaac
acactactctctggggatgcctgggtcctccagacattccgtatcgagcactcccccaac
gagaccttggcccaggccaacggcagctttgtgcgggcaactgtgcatgactacaggctg
gttctcaaccggagcctccccatctcggagaaccgctccctgcagctgaccgtgctggtc
aatgactcggacttccagggccccggggagggcaccctcttcctccacttcaacgtgtcc
gtgctgcctgtcagcttgcacttgcccagcacctacaccttcactgtgagcaggcgggcc
cgccgctttgcccagattgggaaagtctgtgtggaaaactgccaggagttcagcggcatc
cacgtgcagtacaggctgcagctctccagcaccaactgcagtgtcctgggggtggtcacc
tcagcagaggacaccacagggaaccttttcgtgaaccacacagaagccctgcagcggccc
gattgctctcaactccggtacacggtagtggctgccgaccggccaacccgcaagcagacc
caggccctgctggttgtcaccgtggaggggacatatgtggctgaggagccaggctgcccc
ctgtcctgtgcagtcagcaagagacgccctgaatgtgaggagtgcggcggcctgggctct
ctgacgggcaggtgcgagtggagacagggagatggcaaaggaatcaccaggaacttctcc
acctgctcccccagcatcaagacctgccccgacggccactgtgatgccgtggagagcaga
aatgtcaacatctgcccccaggactgcctccggggcggcagcatcattggtgggcatgag
ccaggggagcgctgggggattaaagctggcttcggtatctgcaactgtttcccagaggag
aagaagtgcttctgcgaacctgaagacagccaggagccgctgtgtgacgagctctgccgc
acggtgatcgcggccgctgtgctcttctccttcgtcgtctccatgctgctctccaccttc
tgcatccaccgctaccacaagaacgcccacaagccacccattgcctctgctgagatgacc
ttccgccggcctgcccaggccttcccggtcagctactcctcgtccggcgcccgccggccc
tctatggactccatggagaaccaggtctctgtggacgccttcaagatcccggaggatcca
aagtgggaattccctcgaaagaacttggttcttgggaaaaccctgggagaaggcgaattt
ggaaaagtggttaaggcgacagccttccggctaaaaggcaaagcagggtacacaaccgtg
gccgtgaagatgctgaaagagaacgcttccccaagtgagctgcgggacctgctgtcagag
ttcaacctcctgaagcaggtcaaccacccacatgtcatcaagctgtacggggcctgcagc
caggacggcccgctcttcctcattgtggagtatgccaagtacggttccctgcggggcttc
ctccgagagagccgcaaggcggggcccggctacgtgggcagtggaggcagccgcagctcc
agctacctggacaaccccgaggagcgggccctgaccatgggcgacctcatctccttcgcc
tggcagatctctcgggggatgcggtacctggctgagatgaagcttgtccatcgggacttg
gcagccagaaatgtcctggtagctgaggggcggaagatgaagatttcggattttggcctg
tcccgagacgtttatgaagaggattcctatgtgaagaggagcaagggtcggattccagtc
aaatggatggcaattgagtctcttttcgatcatatctacaccacccaaagtgatgtgtgg
tcctttggtgtcctgctgtgggagattgtgactctggggggcaacccctaccctgggatc
cctccggagcggcttttcaacctcctgaagacaggctaccggatggagaggcccgacaac
tgcagtgaggagatgtacggtctcatgctgcagtgttggaagcaggaaccagacaagagg
ccagtgtttgctgacatcagcaaagacctggaaaagatgatggttaagaacagagactac
ttggacctggctgcctccaccccatccgactccctgctttatgacgacggcctctcggag
gaggagacgcccctggtggactgtaataatgctcccctccctcgagccctcccctccacg
tggattgaaaacaaactctatggcatgtcagacccgaactggcctgaagagagtcctgta
ccactcacgagagctgatggcactaacactgtgtgtccaagatatgcaaatgatagtgta
tatgctaactggatggtttcaccctcagcggcacaattaatggacgcatttgatagttaa
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