Panthera uncia (snow leopard): 125933954 Help Entry 125933954         CDS       T08832                                  Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism puc  Panthera uncia (snow leopard) Pathway puc04022   cGMP-PKG signaling pathway puc04068   FoxO signaling pathway puc04081   Hormone signaling puc04140   Autophagy - animal puc04152   AMPK signaling pathway puc04211   Longevity regulating pathway puc04213   Longevity regulating pathway - multiple species puc04910   Insulin signaling pathway puc04920   Adipocytokine signaling pathway puc04923   Regulation of lipolysis in adipocytes puc04930   Type II diabetes mellitus puc04931   Insulin resistance puc04932   Non-alcoholic fatty liver disease puc04935   Growth hormone synthesis, secretion and action puc05010   Alzheimer disease puc05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:puc00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     125933954    04022 cGMP-PKG signaling pathway     125933954    04152 AMPK signaling pathway     125933954   09133 Signaling molecules and interaction    04081 Hormone signaling     125933954  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     125933954  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     125933954    04923 Regulation of lipolysis in adipocytes     125933954    04920 Adipocytokine signaling pathway     125933954    04935 Growth hormone synthesis, secretion and action     125933954   09149 Aging    04211 Longevity regulating pathway     125933954    04213 Longevity regulating pathway - multiple species     125933954  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     125933954   09164 Neurodegenerative disease    05010 Alzheimer disease     125933954   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     125933954    04932 Non-alcoholic fatty liver disease     125933954    04931 Insulin resistance     125933954 BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH MEKK4_N Motif Other DBs NCBI-GeneID:  125933954 NCBI-ProteinID:  XP_049503169 LinkDB All DBs Position A1 Genome browser AA seq 1329 aa AA seqDB search MASPPLHGPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGDEAAAA GGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYF AVAAENEQEQEGWYRALTDLVSEGRAGAGDAPPAAATAASCSASLPGALGGSAGAAAADD SYGLVAPASAAYREVWQVNLKPKGLGQSRNLTGVYRLCLSARTIGFVKLNCEQPSVTLQL MNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFRP RSKSQSSGSSSTHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRVR TASEGDGGAAAAGAGAAGGRPVSVAGSPLSPGPVRTPLSRSHTLSGGGGGGGRAGKVALA PAGGALQHSRSMSMPVAHSPPAATSPSSLSSSSGHGSGSYPPPPGPHPHLQHPLHQPASQ RPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGELY GYMTMDRPLSHCGRPYRRVSGDGAQDVDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTL MRVSFSGSSGRLCPSCPASSPKAAYHPYPEDYGDVEIGSHRSSSSNLGTDDGYMPMTPGA ALTGGGSGSCRSDDYMPMSPTSVSAPKQILQPRAAAAALPPAGAPVSMPAAGRAFPASGG SYKASSPAESSPEDSGYMRMWCGSKLSMENADSKLLPNGDYLNMSPSDAGASGTPPDFSA ALHGSGEMLRGVPGYCHSSLPRSYKAPYTCNGDNNDQYVLMSSPVGRILEEERLEPPASP GTAPSSGCGGGGHAQPPHPAVPSPGRPSGSVGGRPEGFLNQRCRAVRPTRLSLEGLQTLP SMHEYPLPPEPKSPGEYINIDFGDAGARLSPPAPPLLASAASSSSLLSASSPASSLGSGT PGTSGDSRQRSPLSDYMNLDFSSPKSPKPGPQGGDPVGSLDALLSPEASSPYPPLPPRPA APASALQQQPLPPPPLGELYRLPPAPAAQGPSAASSSSSETGDNGDYTEMAFGVAATPPQ PIAAPPKPEGARVTSPTSGVKRLSLRDQVSGVEAFLQASQPPDPHRGAKVIRADPQGGRR RHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGAGGGGLAGGDERPTSPR QLQPPPPQQARPWLPSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDEPGLSPG PQQLPHPQPGDKSAWGRTRSLGGLLSAVGGSSTGGVCGGPGPGALPSANTYASIDFLSHH LKEATIVKE NT seq 3990 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgctgcacgggccccccgggccggcgggtggcgacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgacgaggcggcggcggcg ggcggggggccggcgccgcagccgccgcggctcgagtactacgagagcgagaagaagtgg cggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgtctgaatatcaac aagcgcgccgacgccaagcacaagtacctgatcgcgctctacaccaaggacgagtacttc gccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcaccgacctg gtcagcgagggccgcgcgggcgccggcgacgcaccccccgccgccgccaccgccgcgtcc tgcagcgcctccctgcccggcgccctgggcggctcggccggcgccgccgcggccgatgac agctacgggctggtggcgcccgcctcggccgcctaccgcgaggtgtggcaggtgaacctg aagcccaagggcctgggccagagcaggaacctgacgggcgtgtaccgcttgtgcctgtcg gcgcgcaccatcggctttgtgaaacttaactgtgagcagccgtcggtgacgctgcagctc atgaacattcgccgctgcggccactcggacagcttcttcttcatcgaggtgggccggtcg gccgttacgggcccaggtgagctgtggatgcaggccgacgactcggtggtggctcagaac atccacgagaccatcctggaggctatgaaggcgctcaaggagctcttcgagttccggccg cgcagcaagagccagtcgtcgggctcgtcctccacacaccccatcagcgtccccggcgcg cgccgccaccaccacctggtcaacctgccccccagccagacgggcctggtgcgccgctcg cgcaccgacagcctggccgccaccccgccggcagccaagtgcagctcgtgccgggtgcgc acggccagcgagggcgacggcggcgcggcggcggcgggggccggggcggcgggcggcagg cccgtgtcggtggccgggagtcccctgagccccggaccggtgcgaacgcccctgagccgc tcgcacaccctgagcggcggcggcggcggcggcggccgcgcgggcaaggtggcgctggcg ccggcagggggcgccctgcaacacagccgctccatgtccatgcccgtggcgcactcgccc ccagcagccaccagcccaagcagcctgtcgtccagcagcgggcatggctccggctcctac ccgccgcctccgggcccgcacccgcacctgcagcaccccctgcaccagcccgcgagccag cggccctccagcggcagcgcctcggcctcggggtcccccagcgaccccggcttcatgtct ctggacgagtacggctccagccctggggacctgagagccttctgcagccaccggagcaac acgcccgagtccattgcagagacgcccccggcccgggacggcagcgggggcgagctgtac gggtacatgaccatggaccggcccctgagccactgtggccgcccctaccgcagagtctcc ggggacggggcccaggacgtggacagaggcctgaggaagcggacgtactccctgaccaca cctgcccggcagcgtcccgtgccccagccctcctctgcgtccctggacgaatacaccctg atgcgggtctccttctctggcagctccggccgcctctgcccgtcctgccccgcctcgtct cccaaagcggcctaccacccctaccccgaggactacggggatgtcgagatcggttcccac aggagctccagcagtaacctgggcacggacgacggctacatgcccatgacccccggcgcg gccctcacggggggtggcagtggcagctgtaggagtgacgactacatgcctatgagcccc accagcgtgtccgccccaaagcagatcctgcagcctcgggctgccgctgcggccttgccc cccgcgggagcgccggtgtccatgcccgcggccggcagggccttcccggccagcgggggc agctacaaggcgagctccccggcggagagctcccccgaggacagcgggtacatgcgtatg tggtgtggctccaagctgtccatggagaacgcagacagcaagctgctgcccaacggggac tacctcaacatgtcccccagcgacgcaggcgcctccgggacccctcccgacttctccgcc gccttgcatggcagcggggagatgctcaggggagtgcccggctattgccacagctccctg ccccgctcctacaaggctccctacacctgcaacggggacaacaacgaccagtatgtgctc atgagctctccggtggggcgcatcctggaagaggagaggctggagccgccggccagccca gggaccgcgccgtccagcggctgcggcggtggcggccacgcccagcctcctcacccagca gtgccttcgcctggcaggccaagtggcagcgttggcggccgcccagagggcttcctgaac cagcgctgccgggccgtgcggcccacgcgcctgtccctggaggggcttcagaccctgccc agcatgcacgagtacccgctgccacccgagcccaagagccccggtgagtacatcaacatt gacttcggcgacgcgggagcccgcctgtcgcctcccgcacccccgctgctggcctcggcc gcctcgtcgtcctcgctgctgtccgccagcagcccggcctcctccctgggctcgggcacc ccaggcacgagcggcgacagccgacagcgctccccgctgtccgactacatgaacctcgac ttcagctcgcccaagtcacccaagccgggcccccagggcggggaccccgtgggctcgctg gacgccctcctgtcccccgaggcctcctccccctacccaccgctgcccccgcgccctgcg gcgcccgcctccgccctgcagcagcagccgctgcctccgccccctctaggcgagctgtac cgcctgccccccgcccccgccgcccagggccccagcgctgcctcctcgtcgtcctcggag actggggacaatggtgactacaccgagatggccttcggcgtggctgccaccccgccgcaa cccatcgccgcccccccgaagccggaaggtgcccgcgtgaccagccccacgtccggcgtc aagaggctgagtctcagggatcaagtgtcgggagtggaggccttcctgcaggccagccag cccccggacccgcaccggggggccaaggtcatccgcgcagacccgcaggggggccgccgc cgccacagctccgagaccttctcctcgaccaccactgtgacccccgtgtccccgtccttc gcccacaacccgaagcgccacaactcggcttccgtggaaaacgtctctctcaggaaaagc agcgaaggggctggcggcggcggcctggctgggggcgacgagcgccccacgtccccccgc cagctgcagccaccgcccccccagcaggcgcggccgtggctacccagtcagccagggggc ttggtcgggtgccccgggggcagcggctctccgatgcgcagggagacctctgccggcttc cagaacggcctcaactacatcgccatcgacgtgagggacgaacctgggctgtcacccggc ccacagcagcttccgcatccgcagccaggagacaagagcgcctggggccggacccggagc ctggggggtctcctcagcgcggtggggggcagcagcaccggtggggtgtgcggggggccc ggccctggcgccctgccctccgccaacacctatgccagcattgacttcttgtcgcatcac ctgaaggaggccaccattgtgaaagagtga

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