Panthera uncia (snow leopard): 125934730
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Entry
125934730 CDS
T08832
Name
(RefSeq) 3-oxo-5-alpha-steroid 4-dehydrogenase 1 isoform X1
KO
K12343
3-oxo-5-alpha-steroid 4-dehydrogenase 1 [EC:
1.3.1.22
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc00140
Steroid hormone biosynthesis
puc01100
Metabolic pathways
Module
puc_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
puc_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
125934730
Enzymes [BR:
puc01000
]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.22 3-oxo-5alpha-steroid 4-dehydrogenase (NADP+)
125934730
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Motif
Pfam:
Steroid_dh
DUF1295
PEMT
Motif
Other DBs
NCBI-GeneID:
125934730
NCBI-ProteinID:
XP_049504250
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Position
A1
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AA seq
332 aa
AA seq
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MEPAEGSHLDALAYLECALGLLGSVLLKLVRSAYGRYASPRPACRVPARAAWALQELPSL
AVPLWVCARTAAERLRHAPNRVLLAMFLVHYAQRSRFFSNRRFPVCRGQRGGDLLVPSCQ
PLAWSPGGAQVSSRTTHRFAVRSRNKLSHPPPCVPSTKGPLPCLRGTRAHWSLIFPLLIR
GGKPMPLYTCTLAFMFCVYNGYLQSRYLSQYAVYADDWVTDPRFLLGFCLWLIGMLINIH
SDHILRNLRKPGETGYKIPRGGLFEYVTAANYFGEVVEWCGYALASWSVQGGAFAAFTFC
ILVSRAQQHHQWYLEKFEDYPKFRKIIIPFLL
NT seq
999 nt
NT seq
+upstream
nt +downstream
nt
atggagccggccgagggctcccacctggacgcgctcgcctacctggagtgcgcgctgggc
ttgctgggctccgtgctgctgaagctggtgcgctcggcctacgggcgctacgcgtctccg
cgccccgcctgccgcgtgccggcgcgggccgcctgggcgctgcaggagctgccctcgctg
gccgtgccgctctgggtgtgcgcccgcacggctgccgagcgcctccgccacgcgcccaac
cgcgtcctcctggccatgttcctcgtccactacgcgcaacgttctcggtttttttccaac
cgtcgctttcccgtgtgtcggggacaacgcggcggtgacctcttagtcccgtcgtgccaa
cctctggcgtggtctcccgggggagcccaggtgtcatcgcgaaccacacaccgctttgct
gtccggagcaggaataaacttagccaccctccaccgtgcgtcccgagcacgaagggcccg
cttccctgtctgcgcgggacacgtgcgcactggtccttgattttcccacttctgatccga
ggaggaaagccgatgcccctgtacacgtgtacgttggcgttcatgttctgtgtctataac
ggctacttgcagagcagatatttgagtcagtatgcggtgtatgcggatgactgggtcact
gatccccgatttctactaggtttctgcttatggttaataggcatgctgataaacatccat
tccgaccatatcctgaggaatctccggaaaccaggggagactggatataaaataccaagg
ggaggcttatttgaatacgtaacagcagccaactactttggggaggtggtcgagtggtgt
ggctacgccctggccagctggtccgttcaaggcggggccttcgcggcctttaccttctgt
attttagtctcccgagcacagcagcatcaccagtggtaccttgagaaatttgaagattat
ccaaagttcaggaaaattataatcccgtttttgttgtaa
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