Panthera uncia (snow leopard): 125938936
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Entry
125938936 CDS
T08832
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
puc
Panthera uncia (snow leopard)
Pathway
puc01524
Platinum drug resistance
puc04010
MAPK signaling pathway
puc04071
Sphingolipid signaling pathway
puc04141
Protein processing in endoplasmic reticulum
puc04210
Apoptosis
puc04530
Tight junction
puc04668
TNF signaling pathway
puc04714
Thermogenesis
puc04722
Neurotrophin signaling pathway
puc04932
Non-alcoholic fatty liver disease
puc04936
Alcoholic liver disease
puc05010
Alzheimer disease
puc05012
Parkinson disease
puc05014
Amyotrophic lateral sclerosis
puc05016
Huntington disease
puc05017
Spinocerebellar ataxia
puc05022
Pathways of neurodegeneration - multiple diseases
puc05208
Chemical carcinogenesis - reactive oxygen species
puc05417
Lipid and atherosclerosis
puc05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
puc00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
125938936
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
125938936
04668 TNF signaling pathway
125938936
04071 Sphingolipid signaling pathway
125938936
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
125938936
09144 Cellular community - eukaryotes
04530 Tight junction
125938936
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
125938936
09159 Environmental adaptation
04714 Thermogenesis
125938936
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
125938936
09164 Neurodegenerative disease
05010 Alzheimer disease
125938936
05012 Parkinson disease
125938936
05014 Amyotrophic lateral sclerosis
125938936
05016 Huntington disease
125938936
05017 Spinocerebellar ataxia
125938936
05022 Pathways of neurodegeneration - multiple diseases
125938936
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
125938936
05418 Fluid shear stress and atherosclerosis
125938936
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
125938936
04932 Non-alcoholic fatty liver disease
125938936
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
125938936
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
puc01001
]
125938936
Enzymes [BR:
puc01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
125938936
Protein kinases [BR:
puc01001
]
Serine/threonine kinases: STE group
STE11 family
125938936
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
125938936
NCBI-ProteinID:
XP_049510379
LinkDB
All DBs
Position
B2
Genome browser
AA seq
1366 aa
AA seq
DB search
MSAEAGEGITFSVPPLAEGGSCRRGAAAAAAEGEESQLPPPPPGSFWNVESASAPGTGCP
AATSGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVMAESEALQSLREACETVGATLE
TVHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDNN
SDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFLDTESRDYGASWFKKAFESEPS
LQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCEG
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRACANDLLIDEFLKVSSKKKKTQPKLSALSAGSNEYLRSISLP
VPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFEDH
SAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGTEEPKLKWEHIT
TLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNIK
PHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDEREEQPSNQTVQ
RPHAVIEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKIETNRLLEELVQKEKELQA
LLHQAIEEKDHEIKHLKLKSQPIGIPGVPVCHRDSLGTNAEESELAEWLREKGADEDTIS
RFLAEDYSLEDVLYYVTRDDLKCLRLRGGILCTLWKAITDFRDKQT
NT seq
4101 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggtatcactttctccgtgccacccttggccgagggcggc
agctgccggaggggagcagcggcggcggcggccgagggcgaggagagccagctaccaccg
ccgccgccgggcagcttctggaacgtggagagtgcctccgccccgggcaccgggtgtccc
gctgccacctctgggagcagcgccacccggtgccggggcaactctggtggcggaggcggc
cgacggaccacggtggcgtatgtgatcaacgaagcgagccaggggcagctggtgatggcc
gagagcgaggccctgcagagcctgcgggaggcgtgcgagacggtgggcgccaccctggag
accgtgcattttggtaaactggactttggggaaaccgcggtgctggatcgtttctacaat
gcagatatcgctgtggtggagatgagtgacgccttccgacagccatcgttgttttaccac
ctcggggtcagagaaagtttcagcatggccaacaacatcatcctctactgtgataataat
tcagactctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactggg
aactacacattcgttccttacatgatcactccgcataataaagtctactgctgcgatagc
agcttcatgaaggggttgacagagctcatgcaaccgaacttcgagctgcttcttggaccc
atttgcttacctcttgtggaccgtttcattcaacttctgaaggtggcacaagcaagttcc
agccagtatttccgggaatctatactcaatgatatcaggaaagctcgtaatttatacact
ggtaaagaattggcagctgaattggcaagaattcggcagcgagtagataatattgaagtc
ttgacagcagatattgtcataaacctgttactttcctacagagatatccaggactatgat
tctattgtgaagctggtagagacgttagaaaagctgccaacctttgatttggcttcccat
caccacgtgaagtttcattatgcatttgcactgaataggagaaatctccctggagacaga
gcaaaagctcttgatattatgattcccctggtgcaaagtgaagggcaagttgcttcagat
atgtattgcctagtgggccgaatctacaaagatatgtttttggactctaatttcctggac
actgaaagtagagactatggagcttcttggttcaaaaaggcatttgaatctgagccatca
ctacagtcaggaattaattatgcggtccttctcctggcagctgggcaccagtttgaatct
tcctttgagctccggaaagttggggtgaagctaagtagccttcttggtaaaaagggaaac
ttagaaaaactccagagctactgggaagttggattttttctgggtgccagtgtcctggcc
aatgaccacatgagagtcatccaagcatctgaaaagctttttaaactgaagacgccagca
tggtacctcaagtctattgtagagacaattttgatatataagcattttgtgaaactgact
acagagcagcctgtggccaaacaggagctggtggacttctggatggatttcctggtggag
gccacaaagacagatgttactgtagttaggtttccggtgttaatattagaaccaactaaa
atctatcagccttcatatttgtctatcaacaatgaagttgaggaaaagacaatatctatt
tggcatgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggagtgagtatttctaaatttgaagaacgatgctgttttctttatgtgcttcat
aattctgacgatttccaaatctatttctgtacagaacttcattgtaaaaagttttttgaa
atggtgaacaccattaccgaagagaaggggagaagcacagaggaaggtgattgtgaaggt
gactccttggagtatgactacgaatatgatgagaacggagacagagttgttttaggaaag
ggcacttacgggattgtctacgcaggccgagacctgagcaaccaagtcagaattgctata
aaggaaatcccagaaagagatagcagatactcccagcccctacatgaagaaatagcattg
cataagcatctgaagcataaaaatattgtccagtatctgggctctttcagtgagaatggt
ttcatcaaaatcttcatggagcaggtcccaggaggaagtctttcagctctccttcgttcc
aaatggggcccattgaaggacaatgagcaaacaattggcttctatacaaagcaaatactt
gaaggattaaaatacctccatgacaatcagatagtccaccgggatataaagggtgacaat
gtgttgattaatacctacagtggcgttctcaagatctcagacttcgggacatcaaagagg
cttgctggcattaacccgtgtactgaaacttttactggtacccttcagtatatggcacca
gaaatcatagacaaaggaccaagaggctacgggaaagcagcagacatttggtctttgggc
tgcacgatcatcgaaatggccacagggaaaccacctttttatgaactgggagaaccacaa
gcagctatgttcaaggtgggaatgtttaaagtccacccggagatcccagagtccatgtcc
gcagaggccaaggcgttcatattgaaatgttttgaaccggaccccgacaagagagcctgt
gctaacgacttgcttattgacgagttcttaaaagtttcaagcaaaaagaagaagacgcaa
cctaagctttcagccctctcagctggatcaaatgagtatcttagaagcatatccttgcct
gtgcccgtcttggtggaggacaccagcagcagcagcgaatacggctcggtttctccggac
acggagttgaaggtggatcccttctctttcaagacgagagccaaatcctgtggagagcga
gacgtaaaaggaatacggacactctttctgggcattccagacgaaaatttcgaagaccac
agtgctccaccttcccctgaagagaaagattctggattctttatgctgaggaaggacagt
gagagacgggccactcttcacaggatcctgaccgaagaccaagacaaagttgtgaggaac
ttaatggaatctttggctcaggggactgaagaacctaaactaaaatgggaacacatcaca
accctcattgcaagcctcagagaatttgtgagatccacggaccgaaaaatcatagccacc
acactgtctaagctgaagctagaacttgactttgacagccatggcatcagtcaagttcag
gtggtactcttcggttttcaagatgccgtcaataaagttcttcggaatcataacatcaag
ccacactggatgtttgccttagacagtattatccgaaaggcagtgcagacggccatcacc
attctggtgccagaactgaggccacatttcagcctcgcatctgagagtgataccgcggat
caagaagacttggatgcggaagatgagcgtgaggaacagccttcaaaccaaactgtccaa
agacctcatgctgtcattgaagatgccgtggctacctcaggggtgagcacgctcagttct
actgtatcccatgactcccaaaatgctcaccgatcactcaatgtgcagcttggaaggatg
aaaatagaaactaatagattactggaagaattggttcagaaagagaaagaattacaagca
ctccttcatcaagctattgaagaaaaagaccacgaaattaaacacctgaagcttaagtcc
caaccaataggtattcctggagtgcctgtgtgtcaccgggattctctgggcacaaatgct
gaagagtctgaacttgctgaatggctgagagaaaagggagctgatgaagacactataagt
cggtttctggctgaggattattcactagaggatgttctctactatgttacacgtgatgat
ttaaaatgcctgagactaaggggaggaatactctgcacgctgtggaaggccatcactgac
tttcgagacaaacagacttga
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