KEGG PATHWAY: pvb00542

PATHWAY: pvb00542

Entry

pvb00542                    Pathway

Name

O-Antigen repeat unit biosynthesis - Pseudoalteromonas viridis

Description

O-antigen is a repetitive glycan polymer synthesized as the most variable part in the lipopolysaccharide (LPS) biosynthesis (map00541). Structural diversity of O-antigen repeat units results from genetic diversity as summarized here for completely sequenced Escherichia coli genomes, many of which are for pathogenic strains.

Class

Metabolism; Glycan biosynthesis and metabolism

Pathway map

pvb00542

O-Antigen repeat unit biosynthesis

Organism

Pseudoalteromonas viridis [GN:pvb]

Gene

J5X90_03390

wecA; UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase [KO:K02851] [EC:2.7.8.33 2.7.8.35]

Reference

PMID:15625181

Authors

Riley JG, Menggad M, Montoya-Peleaz PJ, Szarek WA, Marolda CL, Valvano MA, Schutzbach JS, Brockhausen I

Title

The wbbD gene of E. coli strain VW187 (O7:K1) encodes a UDP-Gal: GlcNAc{alpha}-pyrophosphate-R {beta}1,3-galactosyltransferase involved in the biosynthesis of O7-specific lipopolysaccharide.

Journal

Glycobiology 15:605-13 (2005)
DOI:10.1093/glycob/cwi038

Reference

PMID:10517601

Authors

Marolda CL, Feldman MF, Valvano MA

Title

Genetic organization of the O7-specific lipopolysaccharide biosynthesis cluster of Escherichia coli VW187 (O7:K1).

Journal

Microbiology 145 ( Pt 9):2485-95 (1999)
DOI:10.1099/00221287-145-9-2485

Reference

PMID:22875852

Authors

Greenfield LK, Richards MR, Li J, Wakarchuk WW, Lowary TL, Whitfield C

Title

Biosynthesis of the polymannose lipopolysaccharide O-antigens from Escherichia coli serotypes O8 and O9a requires a unique combination of single- and multiple-active site mannosyltransferases.

Journal

J Biol Chem 287:35078-91 (2012)
DOI:10.1074/jbc.M112.401000

Reference

PMID:17600060

Authors

Wang W, Perepelov AV, Feng L, Shevelev SD, Wang Q, Senchenkova SN, Han W, Li Y, Shashkov AS, Knirel YA, Reeves PR, Wang L

Title

A group of Escherichia coli and Salmonella enterica O antigens sharing a common backbone structure.

Journal

Microbiology 153:2159-67 (2007)
DOI:10.1099/mic.0.2007/004192-0

Reference

PMID:7517391

Authors

Stevenson G, Neal B, Liu D, Hobbs M, Packer NH, Batley M, Redmond JW, Lindquist L, Reeves P

Title

Structure of the O antigen of Escherichia coli K-12 and the sequence of its rfb gene cluster.

Journal

J Bacteriol 176:4144-56 (1994)
DOI:10.1128/jb.176.13.4144-4156.1994

Reference

PMID:9004408

Authors

Reeves PR, Hobbs M, Valvano MA, Skurnik M, Whitfield C, Coplin D, Kido N, Klena J, Maskell D, Raetz CR, Rick PD.

Title

Bacterial polysaccharide synthesis and gene nomenclature.

Journal

Trends Microbiol 4:495-503 (1996)
DOI:10.1016/S0966-842X(97)82912-5

Reference

PMID:1280216

Authors

Jann B, Shashkov AS, Gupta DS, Jann K.

Title

The O18 antigens (lipopolysaccharides) of Escherichia coli. Structural characterization of the O18A, O18A1, O18B and O18B1-specific polysaccharides.

Journal

Eur J Biochem 210:241-8 (1992)
DOI:10.1111/j.1432-1033.1992.tb17414.x

Reference

PMID:2482127

Authors

Jansson PE, Kenne L, Widmalm G.

Title

Structure of the O-antigen polysaccharide from Escherichia coli O18ac: a revision using computer-assisted structural analysis with the program CASPER.

Journal

Carbohydr Res 193:322-5 (1989)
DOI:10.1016/0008-6215(89)85135-3

Reference

PMID:20434495

Authors

Li D, Liu B, Chen M, Guo D, Guo X, Liu F, Feng L, Wang L

Title

A multiplex PCR method to detect 14 Escherichia coli serogroups associated with urinary tract infections.

Journal

J Microbiol Methods 82:71-7 (2010)
DOI:10.1016/j.mimet.2010.04.008

Reference

PMID:8839182

Authors

Manca MC, Weintraub A, Widmalm G.

Title

Structural studies of the Escherichia coli O26 O-antigen polysaccharide.

Journal

Carbohydr Res 281:155-60 (1996)
DOI:10.1016/0008-6215(95)00333-9

Reference

PMID:12384293

Authors

D'Souza JM, Wang L, Reeves P

Title

Sequence of the Escherichia coli O26 O antigen gene cluster and identification of O26 specific genes.

Journal

Gene 297:123-7 (2002)
DOI:10.1016/S0378-1119(02)00876-4

Reference

PMID:11976290

Authors

Wang L, Huskic S, Cisterne A, Rothemund D, Reeves PR

Title

The O-antigen gene cluster of Escherichia coli O55:H7 and identification of a new UDP-GlcNAc C4 epimerase gene.

Journal

J Bacteriol 184:2620-5 (2002)
DOI:10.1128/JB.184.10.2620-2625.2002

Reference

PMID:19560364

Authors

Liu XW, Xia C, Li L, Guan WY, Pettit N, Zhang HC, Chen M, Wang PG

Title

Characterization and synthetic application of a novel beta1,3-galactosyltransferase from Escherichia coli O55:H7.

Journal

Bioorg Med Chem 17:4910-5 (2009)
DOI:10.1016/j.bmc.2009.06.005

Reference

PMID:17634307

Authors

Fitzgerald C, Collins M, van Duyne S, Mikoleit M, Brown T, Fields P

Title

Multiplex, bead-based suspension array for molecular determination of common Salmonella serogroups.

Journal

J Clin Microbiol 45:3323-34 (2007)
DOI:10.1128/JCM.00025-07

Reference

PMID:23848592

Authors

Liu B, Knirel YA, Feng L, Perepelov AV, Senchenkova SN, Reeves PR, Wang L

Title

Structural diversity in Salmonella O antigens and its genetic basis.

Journal

FEMS Microbiol Rev 38:56-89 (2014)
DOI:10.1111/1574-6976.12034

Reference

PMID:1291048

Authors

Gamian A, Romanowska E, Ulrich J, Defaye J.

Title

The structure of the sialic acid-containing Escherichia coli O104 O-specific polysaccharide and its linkage to the core region in lipopolysaccharide.

Journal

Carbohydr Res 236:195-208 (1992)
DOI:10.1016/0008-6215(92)85016-S

Reference

PMID:11404020

Authors

Wang L, Briggs CE, Rothemund D, Fratamico P, Luchansky JB, Reeves PR

Title

Sequence of the E. coli O104 antigen gene cluster and identification of O104 specific genes.

Journal

Gene 270:231-6 (2001)
DOI:10.1016/S0378-1119(01)00471-1

Reference

PMID:24957618

Authors

Wang S, Czuchry D, Liu B, Vinnikova AN, Gao Y, Vlahakis JZ, Szarek WA, Wang L, Feng L, Brockhausen I

Title

Characterization of two UDP-Gal:GalNAc-diphosphate-lipid beta1,3-galactosyltransferases WbwC from Escherichia coli serotypes O104 and O5.

Journal

J Bacteriol 196:3122-33 (2014)
DOI:10.1128/JB.01698-14

Reference

PMID:26391208

Authors

Czuchry D, Desormeaux P, Stuart M, Jarvis DL, Matta KL, Szarek WA, Brockhausen I

Title

Identification and Biochemical Characterization of the Novel alpha2,3-Sialyltransferase WbwA from Pathogenic Escherichia coli Serotype O104.

Journal

J Bacteriol 197:3760-8 (2015)
DOI:10.1128/JB.00521-15

Reference

PMID:29063990

Authors

Czuchry D, Szarek WA, Brockhausen I

Title

Identification and biochemical characterization of WbwB, a novel UDP-Gal: Neu5Ac-R alpha1,4-galactosyltransferase from the intestinal pathogen Escherichia coli serotype O104.

Journal

Glycoconj J 35:65-76 (2018)
DOI:10.1007/s10719-017-9799-y

Reference

PMID:18156323

Authors

Stevenson G, Dieckelmann M, Reeves PR

Title

Determination of glycosyltransferase specificities for the Escherichia coli O111 O antigen by a generic approach.

Journal

Appl Environ Microbiol 74:1294-8 (2008)
DOI:10.1128/AEM.02660-07

Reference

PMID:9774562

Authors

Wang L, Curd H, Qu W, Reeves PR

Title

Sequencing of Escherichia coli O111 O-antigen gene cluster and identification of O111-specific genes.

Journal

J Clin Microbiol 36:3182-7 (1998)
DOI:10.1128/JCM.36.11.3182-3187.1998

Reference

PMID:15629947

Authors

Feng L, Senchenkova SN, Tao J, Shashkov AS, Liu B, Shevelev SD, Reeves PR, Xu J, Knirel YA, Wang L

Title

Structural and genetic characterization of enterohemorrhagic Escherichia coli O145 O antigen and development of an O145 serogroup-specific PCR assay.

Journal

J Bacteriol 187:758-64 (2005)
DOI:10.1128/JB.187.2.758-764.2005

Reference

PMID:22556057

Authors

Gao Y, Liu B, Strum S, Schutzbach JS, Druzhinina TN, Utkina NS, Torgov VI, Danilov LL, Veselovsky VV, Vlahakis JZ, Szarek WA, Wang L, Brockhausen I

Title

Biochemical characterization of WbdN, a beta1,3-glucosyltransferase involved in O-antigen synthesis in enterohemorrhagic Escherichia coli O157.

Journal

Glycobiology 22:1092-102 (2012)
DOI:10.1093/glycob/cws081

Reference

PMID:9673232

Authors

Wang L, Reeves PR

Title

Organization of Escherichia coli O157 O antigen gene cluster and identification of its specific genes.

Journal

Infect Immun 66:3545-51 (1998)
DOI:10.1128/IAI.66.8.3545-3551.1998

Reference

PMID:28696276

Authors

Hong Y, Liu MA, Reeves PR

Title

Progress in Our Understanding of Wzx Flippase for Translocation of Bacterial Membrane Lipid-Linked Oligosaccharide.

Journal

J Bacteriol 200:e00154-17 (2018)
DOI:10.1128/JB.00154-17

Reference

PMID:31778182

Authors

Liu B, Furevi A, Perepelov AV, Guo X, Cao H, Wang Q, Reeves PR, Knirel YA, Wang L, Widmalm G.

Title

Structure and genetics of Escherichia coli O antigens.

Journal

FEMS Microbiol Rev fuz028 (2019)
DOI:10.1093/femsre/fuz028

KO pathway

ko00542

LinkDB

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