Prionailurus viverrinus (fishing cat): 125149652 Help Entry 125149652         CDS       T09889                                  Symbol INSR Name (RefSeq) insulin receptor isoform X1   KO K04527   insulin receptor [EC:2.7.10.1] Organism pviv  Prionailurus viverrinus (fishing cat) Pathway pviv04010   MAPK signaling pathway pviv04014   Ras signaling pathway pviv04015   Rap1 signaling pathway pviv04022   cGMP-PKG signaling pathway pviv04066   HIF-1 signaling pathway pviv04068   FoxO signaling pathway pviv04072   Phospholipase D signaling pathway pviv04081   Hormone signaling pviv04150   mTOR signaling pathway pviv04151   PI3K-Akt signaling pathway pviv04152   AMPK signaling pathway pviv04211   Longevity regulating pathway pviv04213   Longevity regulating pathway - multiple species pviv04520   Adherens junction pviv04910   Insulin signaling pathway pviv04913   Ovarian steroidogenesis pviv04923   Regulation of lipolysis in adipocytes pviv04930   Type II diabetes mellitus pviv04931   Insulin resistance pviv04932   Non-alcoholic fatty liver disease pviv04960   Aldosterone-regulated sodium reabsorption pviv05010   Alzheimer disease pviv05415   Diabetic cardiomyopathy Brite KEGG Orthology (KO) [BR:pviv00001]  09130 Environmental Information Processing   09132 Signal transduction    04010 MAPK signaling pathway     125149652 (INSR)    04014 Ras signaling pathway     125149652 (INSR)    04015 Rap1 signaling pathway     125149652 (INSR)    04066 HIF-1 signaling pathway     125149652 (INSR)    04068 FoxO signaling pathway     125149652 (INSR)    04072 Phospholipase D signaling pathway     125149652 (INSR)    04022 cGMP-PKG signaling pathway     125149652 (INSR)    04151 PI3K-Akt signaling pathway     125149652 (INSR)    04152 AMPK signaling pathway     125149652 (INSR)    04150 mTOR signaling pathway     125149652 (INSR)   09133 Signaling molecules and interaction    04081 Hormone signaling     125149652 (INSR)  09140 Cellular Processes   09144 Cellular community - eukaryotes    04520 Adherens junction     125149652 (INSR)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     125149652 (INSR)    04923 Regulation of lipolysis in adipocytes     125149652 (INSR)    04913 Ovarian steroidogenesis     125149652 (INSR)   09155 Excretory system    04960 Aldosterone-regulated sodium reabsorption     125149652 (INSR)   09149 Aging    04211 Longevity regulating pathway     125149652 (INSR)    04213 Longevity regulating pathway - multiple species     125149652 (INSR)  09160 Human Diseases   09164 Neurodegenerative disease    05010 Alzheimer disease     125149652 (INSR)   09166 Cardiovascular disease    05415 Diabetic cardiomyopathy     125149652 (INSR)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     125149652 (INSR)    04932 Non-alcoholic fatty liver disease     125149652 (INSR)    04931 Insulin resistance     125149652 (INSR)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pviv01001]     125149652 (INSR)   09183 Protein families: signaling and cellular processes    04090 CD molecules [BR:pviv04090]     125149652 (INSR) Enzymes [BR:pviv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.1  receptor protein-tyrosine kinase      125149652 (INSR) Protein kinases [BR:pviv01001]  Receptor tyrosine kinases (RTK)   INSR family [OT]    125149652 (INSR) CD molecules [BR:pviv04090]  Proteins   125149652 (INSR) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Recep_L_domain Pkinase Furin-like Insulin_TMD fn3 Ig_DSCAM-DSCAML_C Kinase-like B2 Motif Other DBs NCBI-GeneID:  125149652 NCBI-ProteinID:  XP_047684755 LinkDB All DBs Position A2:5292035..5434329 Genome browser AA seq 1369 aa AA seqDB search MGAGAGRGAATAPLLVAVAALLLGAAGHLYPGEVCPGMDIRNNLTRLHELANCSVIEGHL QILLMFKTRPEDFRDLSFPKLVMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFNYAL VIFEMVHLKELGLYSLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVLNKDDNE ECGDICPGTAKGKTNCPATVINGQFVERCWTHGHCQKVCPTICKSHGCTADGLCCHSECL GNCSEPDDPTKCVACRNFYLDGRCVETCPPPYYHFQDWRCVNFSFCRDLHNKCKNSRRQG CHQYVIHNNRCIPECPSGYTMNSSNLMCTPCLGPCPKVCHILEGEKTIDSVTSAQELRGC TVVNGSLIINIRGGNNLAAELEANLGLIEEISGYLKIRRSYALVSLSFFRKLRLIRGETL EIGNYSFYALDNQNLRQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQE RNDIALKTNGDQASCENELLKFSYIRTSYDKILLKWEPYWPPDFRDLLGFMLFYKEAPYQ NVTEFDGQDACGSNSWTVVDIDPPLRSNDPKSQNHPGWLMRGLKPWTQYAIFVKTLVTFS DERRTYGAKSDIIYVQTDATNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVFWE RQAEDSELYELDYCLKGLKLPSRTWSPPFESEGSQKHNQSEYEESAGECCSCPKTDSQIL KELEESSFRKTFEDYLHNVVFVPRPSRKRRALADAGNVTAAVPTVPGFPNTSSSVPTSPE EHKPFEKVVNKESLVISGLRHFTGYRIELQACNQDAPEERCSVAAYVSARTMPEAKADDI VGPVTHEIFENNVVHLMWQEPKEPNGLIVLYEVSYRRYGDEELHLCVSRRHFALERGCRL RGLPPGNYSVRVRATSLAGNGSWTEATYFYVTDYLDVPSNIAKIIIGPLIFVFLFSVVIG SIYLFLRKRQPDGPLGPLYASSNPEYLSASDVFPCSVYVPDEWEVPREKITLLRELGQGS FGMVYEGNARDIVKGEAETRVAVKTVNESASLRERIEFLNEASVMKGFTCHHVVRLLGVV SKGQPTLVVMELMVHGDLKSYLRSLRPEAENNPGRPPPTLQEMIQMAAEIADGMAYLNAK KFVHRDLAARNCMVAHDFTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVF TTSSDMWSFGVVLWEITSLAEQPYQGLSNEQVLKFVMDGGYLDQPDNCPERVTDLMHMCW QFNPKMRPTFLEIVDLLKDDLHPSFPEVSFFHSEENKAPESEELEMEFEDMESVPLDRAS HSQREEAGGRDGVSSLGLKRNYEDHIPYTHMNGGKKNGRILTLPRSNPS NT seq 4110 nt NT seq  +upstreamnt  +downstreamnt atgggcgccggggctgggcggggggcggccaccgcgccgctgctggtggcggtggccgcg ctgctgctgggcgccgcgggccacctgtaccccggagaggtctgccctggcatggatatc cggaacaacctgacgaggctgcacgaactggccaactgctcggtcattgaaggtcatttg cagatactgctcatgttcaaaacgaggcccgaggacttccgagacctcagtttccccaaa ctcgtcatgatcactgattacctgctgctcttccgggtgtacgggctggagagcctgaag gacctcttccccaacctcacggtcatccggggctcgcgcctcttcttcaactacgcgctg gtcatcttcgagatggtgcacctgaaggagcttggcctctacagcttgatgaacattacc cggggctccgtccgcatcgagaagaataatgagctgtgctacctggccaccatcgactgg tcgcgcatcctggattcggtggaggataattacattgtgttgaacaaagacgacaacgag gagtgtggggacatttgtccaggcactgcaaagggcaagaccaactgccctgccactgtc atcaacgggcagtttgtggagcgttgttggacacacggccattgccagaaagtttgtccg accatctgcaagtcgcacggctgcacggccgacggcctctgctgccacagcgagtgtttg ggcaactgctctgagcccgacgaccccaccaagtgcgtggcctgtcgcaacttctacctg gacggcaggtgtgtggagacctgcccgcccccctactaccacttccaagactggcgctgc gtgaacttcagcttctgccgggacctgcacaataaatgcaagaactcccggagacagggt tgccaccagtatgtcattcacaacaacaggtgcatccctgagtgcccctcggggtacacg atgaattccagcaacctcatgtgtactccctgcctgggcccctgtcccaaggtctgccac atcctggaaggtgagaagaccatcgactcggtgacatctgcccaggagctccgaggctgc accgtcgtcaacggaagcctaatcatcaacattcgagggggcaacaacctggcagctgag ctggaggccaacctcggactcattgaagaaatttctgggtatctgaagatccgaagatcc tatgctcttgtgtcactttcctttttccggaagttacggctgattcggggagagaccttg gaaattgggaactactctttctatgccttggacaaccagaacctgaggcagctatgggac tggagcaaacacaacctcaccatcactcaggggaaactcttcttccactataatcccaaa ctctgcttgtcggaaattcacaagatggaggaggtttcaggaaccaaggggcgccaggag cggaacgacattgccctgaagaccaatggggaccaggcgtcttgtgaaaatgaactactt aaattttcttacattcggacatcttacgacaagatcttgctgaaatgggagccgtactgg ccccccgacttccgagacctccttggcttcatgctcttctacaaagaggccccttaccag aatgtgaccgagttcgacgggcaggacgcgtgtggctccaacagctggacggtggtggac attgacccgcctctgaggtccaatgaccccaagtcgcagaaccacccagggtggctgatg cggggtctcaagccctggacccagtatgccatctttgtcaagaccttggtcaccttttct gatgagcgccgcacgtatggggccaagagtgacatcatctatgtccagaccgatgccacc aacccttccgtccccctggatcctatctcggtttcgaattcctcctctcagatcattctg aagtggaagcctccctcggaccccaatggcaacatcacgcactacctggtgttctgggag aggcaggcggaggacagcgagctgtatgagttggattattgcctcaaagggttgaagctg ccttcccggacctggtccccgccgttcgagtccgagggctcccagaagcacaatcagagt gaatacgaggagtccgctggcgaatgctgctcatgtcccaaaaccgactctcagatcctg aaggagctggaggagtcctctttcaggaagacgttcgaggattacctgcacaatgtggtt ttcgtgcccaggccgtcgcggaagcgcagggccctcgccgacgctgggaacgtgacggcc gccgtgcccacggtgcctggtttccccaacacttccagcagcgtgcccacgagcccggaa gagcacaagcccttcgagaaggtggtgaacaaagagtcgctggtcatctccggcctgcgt cacttcaccggctaccgcatcgagctgcaggcttgcaaccaagatgcccccgaggagagg tgcagcgtggctgcctatgtcagcgccaggaccatgcccgaagccaaggcagacgacatt gttggccctgtgacccatgaaatcttcgagaacaacgtggttcacctgatgtggcaagag cctaaagaacccaatggattgatcgtgctgtatgaagtgagttaccgacggtatggtgat gaggagctgcacctctgtgtctcccgtagacactttgctctggagcggggctgcaggctg cgaggtctgccgccggggaattacagtgtgcgagttcgggccacctccctggcgggcaac ggctcctggacagaagccacttacttctatgtgacagactatttagatgtcccatcgaac attgcaaaaattatcatcgggcctctcatctttgtctttctcttcagtgttgtgattgga agtatttatctattcctgagaaagaggcagccggatggcccactggggccgctgtatgct tcttcaaaccctgagtacctcagtgccagtgatgtgtttccctgctctgtgtatgtgccg gacgagtgggaggtgcctcgggagaagatcactctcctgcgcgagctggggcagggctcc ttcggcatggtgtacgagggcaatgccagggacatcgtcaagggcgaggcggagacccgc gtggcggtgaagacggtcaacgagtccgccagtctgcgagagaggatcgagtttctcaac gaggcctcagtcatgaagggcttcacctgtcatcacgtggtccgcctcctgggggtggtg tccaaaggccagccgacgctggtggtgatggagctgatggttcacggagacctgaagagc tacctccgctccctgcggccggaggctgagaataatcctggccgccctccccctactctg caagagatgattcagatggcggcggagatcgccgacgggatggcgtacctgaatgccaag aagtttgtgcaccgggatctcgcagctcgaaattgcatggtggcccacgacttcaccgtc aaaattggagacttcggaatgaccagagacatctatgaaacggattactaccggaaagga ggcaagggtctgctccccgtgcggtggatggcaccggaatccctgaaggatggggtcttc accacttcttctgacatgtggtcctttggtgtggtcctttgggaaatcaccagcttggcg gaacaaccttaccaaggcctgtctaatgaacaggtgttgaaatttgtcatggacggagga tatttggaccaacctgacaactgtccggagagagtcaccgacctgatgcacatgtgctgg cagttcaatcccaagatgcggcccaccttcctggagatcgttgacctgctcaaggacgac ctgcaccccagctttccggaagtttccttcttccacagcgaggagaacaaggcgcctgag agcgaggagttggaaatggagtttgaggacatggagagcgtccccctggatcgggcctca cactcacagagggaagaggccgggggccgggatggagtgtcctcgctgggcctcaagcgg aactacgaggaccacatcccctacacccacatgaacgggggcaagaaaaacggacggatt ctgaccctgccgaggtcgaatccttcctaa

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