Prionailurus viverrinus (fishing cat): 125160535 Help Entry 125160535         CDS       T09889                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism pviv  Prionailurus viverrinus (fishing cat) Pathway pviv04062   Chemokine signaling pathway pviv04151   PI3K-Akt signaling pathway pviv04217   Necroptosis pviv04550   Signaling pathways regulating pluripotency of stem cells pviv04630   JAK-STAT signaling pathway pviv04658   Th1 and Th2 cell differentiation pviv04659   Th17 cell differentiation pviv05161   Hepatitis B pviv05162   Measles pviv05166   Human T-cell leukemia virus 1 infection pviv05169   Epstein-Barr virus infection pviv05200   Pathways in cancer pviv05203   Viral carcinogenesis pviv05223   Non-small cell lung cancer pviv05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:pviv00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     125160535 (JAK3)    04151 PI3K-Akt signaling pathway     125160535 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     125160535 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     125160535 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     125160535 (JAK3)    04659 Th17 cell differentiation     125160535 (JAK3)    04062 Chemokine signaling pathway     125160535 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     125160535 (JAK3)    05203 Viral carcinogenesis     125160535 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     125160535 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     125160535 (JAK3)    05161 Hepatitis B     125160535 (JAK3)    05162 Measles     125160535 (JAK3)    05169 Epstein-Barr virus infection     125160535 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     125160535 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pviv01001]     125160535 (JAK3) Enzymes [BR:pviv01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      125160535 (JAK3) Protein kinases [BR:pviv01001]  Non-receptor tyrosine kinases   JAK family [OT]    125160535 (JAK3) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl ABC1 Kdo Kinase-like FERM_C_FAK1 Haspin_kinase Motif Other DBs NCBI-GeneID:  125160535 NCBI-ProteinID:  XP_047705503 LinkDB All DBs Position A2:complement(12605667..12623182) Genome browser AA seq 1106 aa AA seqDB search MAPPSEETPLIPQRSCSLSSSEAGTLHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA SGILPVYHSLFALATEDLSYWYPPSHIFSVEDASTQVLLYRLRFYFPNWFGLENCHRFGL RKDLASAILDLPVLEHLFAQHRNDLVSGRLAVGLSLKEQGECLSLAVLDLARMAREQAQQ PEELLKTVSYKACLPPDLRDLIQGLSFVTRKRIRRTVRRALGRVTACQADRHSLMAKYIM DLERLDPARAAETFLVSLPGAAGGQDAPGLLRVAGDSGIHWSPGGHEALQPFCDFPEIVD ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC KEVAPPRLLEEVAEQCHGPITLDFAINKLKTGGSLPGSYVLRRSPQDFDSFLLTVCVQTP LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWDAGLHVDGVALNLTSCCAPRPK EKSNLIVVRRGCSTPTSSLVWPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HEAVDGEARETEVLLKVMDAKHRNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSVMVQ EFVRLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GIPMPISTLDPAKKLQFYEERQHLPAPKWMELATLIQQCMAYEPGQRPSFRAIIRDLNSL ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCR YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYGNKNCSPSAEFLRMMGCERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP SPQDRPTFSALGPQLDTLWSGSRGVA NT seq 3321 nt NT seq  +upstreamnt  +downstreamnt atggcgcctccaagtgaggagacgcccctgatccctcagcgttcctgcagcctctcgtct tcagaggctggtaccctgcacgtgctgctgccccctcggggccccggacccccacaacgc ctgtccttctcctttggggaccattcagctgaagagctatgtgtttgggctgctaaggcc agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctac tggtaccccccgagccacatcttctccgtggaggatgcaagcacccaagtcctgctctac aggctccgcttttacttccccaactggtttgggttggagaattgccaccgcttcgggcta cggaaggacttggccagtgccatccttgacctgccagtcctggagcacctcttcgcccag caccgaaatgacctggtgagcggccgcctcgccgtgggcctcagtctcaaggagcagggt gaatgtctcagcctggcagtgctggacctggctcggatggcccgtgagcaggctcagcag cctgaggagctgctgaagaccgtcagctacaaggcctgcctgccccccgatctgcgcgac ctgatccagggcctgagcttcgtgacgcggaagcgtatccggaggactgtgcgccgggcc ctgggccgcgtgaccgcctgccaggctgacaggcactcgctcatggccaagtacatcatg gacctggagaggctggacccggccagggccgccgagaccttcctcgtgagcctccccggg gctgctggtggccaggatgctccggggctgctccgagtggctggtgacagcggcatccac tggagtccgggaggacacgaggccctccagcccttctgcgactttccagaaattgtggac atcagcatcaagcaggctcctcgtgttggccccgccggggagcaccgcctggtcaccgtc accaggacggacaaccagatcctggaggccgagttcccggggctgcccgcggccctgtcc ttcgtggcgctcgtggacggctacttccggctgacttccgactccagacacttcttctgc aaggaggttgcgccgccgcggctgctggaggaggtggccgagcagtgccacggtcccatc accctggattttgccatcaacaagctcaagaccgggggctcccttcccggctcctatgtt ctccgccgcagcccccaggatttcgacagcttcctcctcactgtctgcgtccagaccccc ttgggtcctgattacaagggctgcctcatccggtgtgaccccacgggaaccttctccctg gctggcctcggccggccccacagcagtcttcgagagctcttggcagcctgctgggatgct gggctgcacgtggatggggttgcgctgaacctcacctcctgctgcgcccccagacccaaa gaaaagtccaacctgatcgtggtgcggagaggttgcagcactcccacatcatcccttgtt tggccccaatcccagtgccagctgagtcagatgacgtttcacaagatccctgctgacagc ctggagtggcatgagaacctgggtcatgggtccttcaccaagatttaccgaggttgtcgc catgaggctgtggacggggaagcccgggagacagaggtgctactcaaagtgatggatgcc aagcacaggaactgcatggagtccttcctggaagcagcgagcctgatgagccaagtgtcg tatcagcacctcgtgttgctccacggcgtgtgcatggctggagacagtgtcatggtgcag gaatttgtgcgcctgggagccctggatacatatctgcgcaagtccggccacctggtacca gccagctggaagctgcaggtgatcaaacagctggcctatgccctcaactatctggaagac aaaggcctcccccatggcaatgtctcagcccggaaggtgctcttggctcgggagggggct gacgggaacctgcccttcatcaagttgagtgaccctggtgtcagccccactgtgctgagc ctggagatgctcactgacaggatcccctgggtggcccctgagtgtctccaggaggcccgg acccttggcttggaagctgacaagtggggtttcggtgccacagtctgggaagtgttcagc gggatcccgatgcccatcagtaccctggatcctgccaagaagctccagttttacgaggaa cgtcagcaccttcccgcccccaagtggatggagctggccacactgatccaacagtgcatg gcctatgagccaggccagaggccctccttccgcgccatcatccgtgacctgaacagcctc atcacttcagattatgagctcctctcagaccccacacctggtgccttggcgccccgtgat gggctgtggaatggcgcccagctctacgcctgccaggaccctaccatttttgaggagaga catctcaagtacatctcacagctgggcaagggcaactttggcagcgtggagctgtgccgc tatgacccgctgggcgacaacacgggggccctagtggctgtgaagcagcttcagcacagc gggccagaccagcagagggacttccagcgcgagatccagatcctcaaagccctccacagc gacttcattgtcaagtaccgcggtgtcagctatggcccgggccgccagagcctgcggctg gtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcgacaccgcgcgcgc ctcgacgccagccgcctgctcctctacgcctcgcagatctgcaagggcatggagtacctg ggctcccgccgctgcgtgcaccgcgacctggcggctcgtaacatcctggtggagagcgag acgcacgtcaagatcgccgactttggcctcgctaagctgctgccgctcgacaaagactac tacgtggtccgcgagcccggccagagccccatcttctggtacgccccagagtccctctct gacaacatcttctcgcgccagtcggacgtctggagcttcggggtcgtcctgtatgagctt ttcacctacggcaacaagaattgcagcccctcagccgagtttctccggatgatgggatgt gagcgagacgtccccgccctctgccgcctcctggagctgctggctgagggccagaggctg cccgcgcctcctgcctgccccggtgaggttcatgagctcatgaagctgtgctgggccccg agcccgcaagatcggccaacattcagtgccctgggcccccagctggatacactgtggagt ggaagccggggggtagcatag

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