Prionailurus viverrinus (fishing cat): 125171008 Help Entry 125171008         CDS       T09889                                  Symbol IRS2 Name (RefSeq) insulin receptor substrate 2   KO K07187   insulin receptor substrate 2 Organism pviv  Prionailurus viverrinus (fishing cat) Pathway pviv04022   cGMP-PKG signaling pathway pviv04068   FoxO signaling pathway pviv04081   Hormone signaling pviv04140   Autophagy - animal pviv04152   AMPK signaling pathway pviv04211   Longevity regulating pathway pviv04213   Longevity regulating pathway - multiple species pviv04910   Insulin signaling pathway pviv04920   Adipocytokine signaling pathway pviv04923   Regulation of lipolysis in adipocytes pviv04930   Type II diabetes mellitus pviv04931   Insulin resistance pviv04932   Non-alcoholic fatty liver disease pviv04935   Growth hormone synthesis, secretion and action pviv05010   Alzheimer disease pviv05206   MicroRNAs in cancer Brite KEGG Orthology (KO) [BR:pviv00001]  09130 Environmental Information Processing   09132 Signal transduction    04068 FoxO signaling pathway     125171008 (IRS2)    04022 cGMP-PKG signaling pathway     125171008 (IRS2)    04152 AMPK signaling pathway     125171008 (IRS2)   09133 Signaling molecules and interaction    04081 Hormone signaling     125171008 (IRS2)  09140 Cellular Processes   09141 Transport and catabolism    04140 Autophagy - animal     125171008 (IRS2)  09150 Organismal Systems   09152 Endocrine system    04910 Insulin signaling pathway     125171008 (IRS2)    04923 Regulation of lipolysis in adipocytes     125171008 (IRS2)    04920 Adipocytokine signaling pathway     125171008 (IRS2)    04935 Growth hormone synthesis, secretion and action     125171008 (IRS2)   09149 Aging    04211 Longevity regulating pathway     125171008 (IRS2)    04213 Longevity regulating pathway - multiple species     125171008 (IRS2)  09160 Human Diseases   09161 Cancer: overview    05206 MicroRNAs in cancer     125171008 (IRS2)   09164 Neurodegenerative disease    05010 Alzheimer disease     125171008 (IRS2)   09167 Endocrine and metabolic disease    04930 Type II diabetes mellitus     125171008 (IRS2)    04932 Non-alcoholic fatty liver disease     125171008 (IRS2)    04931 Insulin resistance     125171008 (IRS2) BRITE hierarchy SSDB OrthologParalogGene clusterGFIT Motif Pfam:  IRS PH PH_11 MEKK4_N TetR_C_6 Motif Other DBs NCBI-GeneID:  125171008 NCBI-ProteinID:  XP_047723996 LinkDB All DBs Position A1:complement(80061025..80093859) Genome browser AA seq 1332 aa AA seqDB search MASPPLHGPPGPAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGDEAAAA GGGPAPQPPRLEYYESEKKWRSKAGAPKRVIALDCCLNINKRADAKHKYLIALYTKDEYF AVAAENEQEQEGWYRALTDLVSEGRAGAGDAPPAAAATAASCSASLPGALGGSAGAAAAD DSYGLVAPASAAYREVWQVNLKPKGLGQSRNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR PRSKSQSSGSSSTHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV RTASEGDGGAAAAGAGAAGGRPVSVAGSPLSPGPVRTPLSRSHTLSGGGGGGGGRAGKVA LAPAGGALQHSRSMSMPVAHSPPAATSPSSLSSSSGHGSGSYPPPPGPHPHLQHPLHQPA SQRPSSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGGE LYGYMTMDRPLSHCGRPYRRVSGDGAQDVDRGLRKRTYSLTTPARQRPVPQPSSASLDEY TLMRVSFSGSSGRLCPSCPASSPKAAYHPYPEDYGDVEIGSHRSSSSNLGTDDGYMPMTP GAALTGGGSGSCRSDDYMPMSPTSVSAPKQILQPRAAAAALPPAGAPVSTPAAGRAFPAS GGSYKASSPAESSPEDSGYMRMWCGSKLSMENADSKLLPNGDYLNMSPSDAGASGTPPDF FSAALHGSGEMLRGVPGYCHSSLPRSYKAPYTCNGDNNDQYVLMSSPVGRILEEERLEPL ASPGTAPSSGCGGGGHAQPPHPAVPSPGRPGGSVGGRPEGFLNQRCRAVRPTRLSLEGLQ TLPSMHEYPLPPEPKSPGEYINIDFGDAGARLSPPAPPLLASAASSSSLLSASSPASSLG SGTPGTSGDSRQRSPLSDYMNLDFSSPKSPKPGPQGGDPVGSLDALLSPEASSPYPPLPP RPAASASALQPQPLPPPPPGELYRLPPAPAAQGPSAASSSSSETGDNGDYTEMAFGVAAT PPQPIAAPPKPEGARVTSPTSGLKRLSLRDQVSGVEAFLQASQPPDPHRGAKVIRADPQG GRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGAGGGGLAGGDERPT SPRQLQPPPPQQARPWLPSQPGGLVGCPGGSGSPMRRETSAGFQNGLNYIAIDVRDEPGL SPGPQQLPHPQPGDKSAWGRTRSLGGLLSAVGGSSTGGVCGGPGPGALPSANTYASIDFL SHHLKEATIVKE NT seq 3999 nt NT seq  +upstreamnt  +downstreamnt atggcgagcccgccgctgcacgggccccccgggccggcgggtggcgacggccccaacctc aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggttacctgcgcaagcag aagcacggccacaagcgcttcttcgtgctgcgcgggcccggcgacgaggcggcggcggcg ggcggggggccggcgccgcagccgccgcggctcgagtactacgagagcgagaagaagtgg cggagcaaggcgggcgccccgaagcgggtcatcgcgctcgactgctgcctgaacatcaac aagcgcgccgacgccaagcacaagtacctgatcgcgctctacaccaaggacgagtacttc gccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcgctcaccgacctg gtcagcgagggccgcgcgggcgccggcgacgcgccccccgccgccgccgccaccgccgcg tcctgcagcgcctccctgcccggcgccctgggcggctcggccggcgccgccgcggccgat gacagctacgggctggtggcgcccgcctcggccgcctaccgcgaggtgtggcaggtgaac ctgaagcccaagggcctgggccagagcaggaacctgacgggcgtgtaccgcctgtgcctg tcggcgcgcaccatcggctttgtgaaacttaactgtgagcagccgtcggtgacgctgcag ctcatgaacattcgccgctgcggccactcggacagcttcttcttcatcgaggtgggccgg tcggccgtcacgggcccaggtgagctgtggatgcaggccgacgactcggtggtggcgcag aacatccacgagaccatcttggaggccatgaaggcgctcaaggagctcttcgagttccgg ccgcgcagcaagagccagtcgtctggctcgtcctccacacaccccatcagcgtccccggc gcgcgccgccaccaccacctggtcaacctgccccccagccagacgggcctggtgcgccgc tcgcgcaccgacagcctggccgccaccccgccggcagccaagtgcagctcgtgtcgggtg cgcacggccagcgagggcgacggcggcgcggcggcggcgggggccggggcggcgggcggc aggcccgtgtcggtggccgggagtcccctgagccccgggccggtgcgaacgcccctgagc cgctcacacaccctgagcggcggcggcggcggcggcggcggccgcgcgggcaaggtggcg ctggcgccggcagggggcgccctgcaacacagccgctccatgtccatgcccgtggcgcac tctcccccagcagccaccagccctagcagcctgtcgtccagcagcgggcacggctccggc tcctacccaccgcctccgggcccgcacccgcacctgcagcaccccctgcaccagcccgcg agccagcggccctccagcggcagcgcctcggcctcagggtcccccagcgaccccggcttc atgtctctggacgagtacggctccagccctggggacctgagagccttctgcagccaccgg agcaacacgcccgagtccattgccgagacgcccccggcccgggacggcagcgggggcgag ctgtacgggtacatgaccatggacaggcccctgagccactgtggccgcccctaccgcaga gtctccggggacggggcccaggacgtggacagaggcctgaggaagcggacgtactccctg accacacctgcccggcagcggcccgtgccccagccctcctctgcgtccctggacgaatac accctgatgcgggtctccttctctggcagctccggccgcctctgcccgtcctgccccgcc tcatctcccaaagcggcctaccacccctaccccgaggactacggggacgtcgagatcggc tcccacaggagctccagcagtaacctgggtacggacgacggctacatgcccatgaccccc ggcgcggccctcacggggggtggcagtggcagctgtaggagtgacgactacatgcctatg agccccaccagcgtgtctgccccaaagcagatcctgcagcctcgggctgccgctgcggcc ttgccccccgcgggagcgccagtgtccacacccgcggccggcagggccttcccggccagc gggggcagctacaaggcaagctccccggcggagagctcccccgaggacagcgggtacatg cgtatgtggtgtggctccaagctgtccatggagaacgcagacagcaagctgctgcccaac ggggactacctcaacatgtcccccagcgacgcgggcgcctcggggacccctcccgacttc ttctcggccgccttgcatggcagcggggagatgctcaggggagtgcccggctattgccac agctccctgccccgctcctacaaggctccctacacctgcaacggggacaacaacgaccag tatgtactcatgagctctccggtggggcgcatcctggaagaggagaggctggagccgctg gccagcccggggacggcgccgtccagcggctgcggcggtggcggccacgcccagcctcct cacccagcagtgccttcgcctggcaggccaggtggcagcgttggcggccgcccagagggc ttcctgaaccagcgctgccgggccgtgcggcccacgcgcctgtccctggaggggcttcag accctgcccagcatgcacgaatacccgctgccgcccgagcccaagagccctggcgagtac atcaacattgacttcggcgatgcgggagctcgcctgtcgcctcccgcgcctccgctgctg gcctcggccgcctcgtcgtcctcgctgctgtccgccagcagcccggcctcctccctgggc tcgggcaccccgggcacgagcggtgacagccgacagcgctccccgctgtccgactacatg aacctcgacttcagctcgcccaagtcacccaagccgggcccccagggcggggaccctgtg ggctcgctggacgccctcctgtcccccgaggcctcctccccctatccgccgctgcccccg cgccctgcggcgtctgcctccgccctgcagccgcagccgctgccgccgccccctccaggc gagctgtaccgcctgccccccgcccccgccgcccagggccccagcgctgcctcctcgtcg tcctcggagactggggacaatggtgactacaccgagatggccttcggcgtggctgccacc ccgccgcaacccatcgccgcccccccgaagccggaaggtgcccgcgtgaccagccccacg tccggcctcaagaggctgagtctcagggatcaagtgtcgggagtggaggccttcctgcag gccagccagcccccggacccgcaccggggggccaaggtcatccgcgcagacccgcagggg ggccgccgccgccacagctccgagaccttctcctcgaccaccactgtgacccccgtgtcc ccgtccttcgcccacaacccgaagcgccacaactcggcctccgtggaaaacgtctctctc aggaaaagcagcgaaggggcgggcggcggtggcctggctgggggcgacgagcgccccacg tccccccgccagctgcagccaccgcccccccagcaggcgcggccgtggctaccgagtcag ccggggggcttggtcgggtgccccgggggcagcggctctccgatgcgcagggagacctct gccggcttccagaacggcctcaactacatcgccatcgacgtgagggacgaacctgggctg tcgcccggcccgcagcagcttccgcatccgcagccgggagacaagagcgcctggggccgg acccgtagcctggggggtctcctcagcgcggtggggggcagcagcaccggtggggtgtgc gggggacccggccccggcgccctgccctccgccaacacctatgccagcattgacttcctg tcgcatcacctgaaggaggccaccattgtgaaagagtga

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