KEGG   Prionailurus viverrinus (fishing cat): 125174832
Entry
125174832         CDS       T09889                                 
Symbol
TIAM1
Name
(RefSeq) rho guanine nucleotide exchange factor TIAM1 isoform X1
  KO
K05731  T-lymphoma invasion and metastasis-inducing protein 1
Organism
pviv  Prionailurus viverrinus (fishing cat)
Pathway
pviv04014  Ras signaling pathway
pviv04015  Rap1 signaling pathway
pviv04024  cAMP signaling pathway
pviv04062  Chemokine signaling pathway
pviv04530  Tight junction
pviv04810  Regulation of actin cytoskeleton
pviv05205  Proteoglycans in cancer
Brite
KEGG Orthology (KO) [BR:pviv00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04014 Ras signaling pathway
    125174832 (TIAM1)
   04015 Rap1 signaling pathway
    125174832 (TIAM1)
   04024 cAMP signaling pathway
    125174832 (TIAM1)
 09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04530 Tight junction
    125174832 (TIAM1)
  09142 Cell motility
   04810 Regulation of actin cytoskeleton
    125174832 (TIAM1)
 09150 Organismal Systems
  09151 Immune system
   04062 Chemokine signaling pathway
    125174832 (TIAM1)
 09160 Human Diseases
  09161 Cancer: overview
   05205 Proteoglycans in cancer
    125174832 (TIAM1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified [BR:pviv04990]
    125174832 (TIAM1)
Domain-containing proteins not elsewhere classified [BR:pviv04990]
 Pleckstrin homology (PH) domain-containing proteins
  Dbl-Like RhoGEF family proteins
   125174832 (TIAM1)
SSDB
Motif
Pfam: PH_Tiam1 Tiam_CC_Ex RhoGEF PH RBD PH_9 PDZ PDZ_2 PDZ_6 PH_11 RNA_pol_Rpc82
Other DBs
NCBI-GeneID: 125174832
NCBI-ProteinID: XP_047730644
LinkDB
Position
C2:complement(146067871..146463924)
AA seq 1591 aa
MGNAESQNVEHEFYGEKHASLGRKHTSRSLRLSHKARRTRHASSGKVIHRNSEVSTRSSS
TPSIPQSLAENGLEPFSQEGTLEDFGSPIWVDRVDMGLRPVSYTDSSVAPSVDSSIVLTA
ASVQSMPDSEESRLYGDDAAYLADGGRRQHPYTSNGPAFMETASFKKKRSKSADIWREDS
LEFSLSDLSQEHLTSNEEILVSTEEKDCEEARGMEPRASPRRLSACQRANSLGDLYAQKN
SGVTANGGPRSKFAGYCRNLVSDIPELANHKMPPAAAEDSVPYSNYNTLPCRKSHCLSEG
ATNPQISHSNSMQGRRAKTTQDVNAGEGSEFADSGIEGATTDTDLLSRRSNATNSSYSPP
TGRAFVGSDSGSSSTGDAARQGVYENFRRELEMSTTNSESLEEAGSAHSDEQSSGTLSSP
GQSDILLTAAQGTVRKAGALAVKNFLVHKKNKKVESATRRKWKHYWVSLKGCTLFFYESD
GRSGIDHNSIPKHAVWVENSIVQAVPEHPKKDFVFCLSNSLGDAFLFQTTSQTELENWIT
AIHSACAAAVARHHHKEDTLRLLKSEIKKLEQKIDMDEKMKKMGEMQLSSVTDSKKKKTI
LDQIFVWEQNLEQFQMDLFRYRCYLASLQGGELPNPKRLLAFASRPTKVAMGRLGIFSVS
SFHALVAARTGETGVRRRTQAMSRSASKRRSRFSSLWGLDTTSKKKQGRPSINQVFGEGS
DAVKKSLEGIFDDTVPDGKREKEMVLPSVHQHNPDCDIWVHEYFTPSWFCLPNNQPALTV
VRPGDTARDTLELICKTHQLDHSAHYLRLKFLIENKMQHYVPKPEEDIYELLYKEIEICP
KVTQNIQIEKSDTASDNYGFSLSSVEEDGVRRLYVNSVKETGLASKKGLKAGDEILEINS
RAAGTLNSSVLKDFLTQPSLGLLVRTYPELVGGVELLDCPPHRADGPADLNDSPLAFLSS
NPGHGLCGEQGSGAETALEETEGPDLESSDETDHSSKSTEQVAAFCRSLHEMNLSDPSPS
PQDSTGPQLATMRQLTDADKLRKVICELLETERTYVKDLNCLMERYLKPLQKETFLTQDE
LDVLFGNLTEMVEFQVEFLKTLEDGVRLVPDLEKLEKVDQFKKVLFSLGGSFLYYADRFK
LYSAFCASHTKVPKVLVKAKTDTAFKAFLDAQNPKQQHSATLESYLIKPIQRILKYPLLL
KELFALTDAESEEHYHLDVAIKTMNKVASHINEMQKIHEEFGAVFDQLIAEQTGEKKEVA
DLSMGDLLLHTTVIWPNPPASLGKWKKEPELAAFVFKTAVVLVYKDGSKQKKKLVGSHRL
SIYEDWDPFRFRHMIPTEALQVRALASADAEANAVCEIVHVKSESEGRPERIFHLCCSSP
ESRKDFLKAVHSILRDKHRRQLLKTESLPSSQQYVPFGGKRLCALKGARPAMSRAVSAPS
KSLGRRRRRLARNRFTIDSDAISASSPEKESQQPPGGGDTDRWVEEQFDLAQYEEQDDIK
ETDILSDDDEFCESVKGAAVDTDLPEQLQAASISQRERGRKSLDSHASRMTQLKKQAALS
GVNGGLEGPSEEVIWVRREDFAPSRKLNTEI
NT seq 4776 nt   +upstreamnt  +downstreamnt
atgggaaacgcagaaagtcaaaatgtagagcatgagttttatggagagaagcatgccagc
ctgggccgcaagcacacgtcgcgctccctgcgcctgtcgcacaaggcgcggcggacgagg
cacgcgtcctcggggaaggtgatccacaggaactccgaagtgagcacgcggtccagcagc
acgcccagcatcccccagtctctggccgaaaatggcctggagcccttctcccaagaaggc
accctggaggacttcggcagccccatctgggtggaccgagtggatatgggcctgagaccc
gtgtcgtacaccgactcttctgtcgctcccagcgtagacagcagcatcgtcctcacagcc
gcctctgtgcagagcatgccagactcggaggagagcaggctttacggggatgacgctgcg
tacttggctgacgggggcaggaggcagcatccctatacatccaatgggcccgctttcatg
gagacggcgagctttaagaagaagcgctccaaatctgcagacatctggcgggaggacagc
ctggaattctcactctccgatctgagccaagaacatttaacaagcaacgaagaaatcttg
gtttccactgaagagaaagactgtgaggaggctcgggggatggaaccccgggcgagtccg
cggcggctcagcgcctgtcagcgtgccaattccctgggtgacttgtacgctcagaaaaac
tccggggtgacggcaaacggggggccaaggagcaaatttgcaggctactgtcggaatctg
gtgtctgatatccccgagcttgcaaaccataagatgccaccggctgctgctgaagactct
gttccttacagtaattacaacacactcccctgtaggaaatctcactgtctttccgaaggt
gccaccaacccacaaattagccatagcaacagcatgcaaggcagaagagcaaaaacaact
caggatgttaatgccggcgagggcagtgagtttgcggacagcgggatcgaaggggccacc
accgacacggacctcctgtccaggcgatccaatgccaccaactccagctactcgcccccc
accggccgcgcctttgtgggcagcgacagcggcagcagctccacgggggatgcggcccgc
cagggggtgtacgagaatttccggcgggagctggagatgagcaccaccaacagcgagagc
ctggaggaggcgggctcggcgcacagcgatgagcagagcagcggcaccctgagctccccg
ggccagtcggacatcctgctcacggccgcgcagggcacggtgcgcaaggccggggcgctg
gccgtcaagaacttcctggtgcacaagaagaacaagaaggtggagtcggccacccggagg
aagtggaagcactactgggtgtccctgaaagggtgcacactcttcttctatgagagcgat
ggtaggtctggaatagaccacaacagcatccctaagcacgccgtgtgggtggagaacagc
attgtgcaggctgtacctgaacaccccaagaaggacttcgtcttctgcctcagcaattcc
ctgggtgatgctttcctctttcagaccaccagccagacggagctggaaaactggatcacc
gccatccactctgcctgcgcggctgctgtggcgagacatcaccacaaagaggacacgctc
cggctcctgaagtctgagatcaaaaaactggaacagaagattgatatggatgagaagatg
aagaaaatgggcgaaatgcagctgtcttcagtcaccgattcgaagaagaagaagactata
ttagatcagatcttcgtttgggagcagaatctcgagcagttccaaatggacctatttcgt
taccgctgttacttagctagcctccaaggtggggaactgccaaaccccaaaaggctactt
gcttttgcaagccgaccaacgaaagtggcaatgggccgccttggaatcttctctgtatca
tccttccatgccctggtggcagcacgcactggtgagaccggagtgagacgtcgtactcag
gccatgtccagatccgcaagcaagcgaaggagcaggttttcttccctttggggtctggac
actacctccaaaaagaagcagggacgccccagcatcaaccaggtgttcggtgagggaagt
gatgctgtaaagaaatctttagagggaatatttgatgacactgttccagatggcaagagg
gagaaagaaatggtcttgcccagcgtccaccagcacaatcccgactgtgacatttgggtc
cacgagtatttcacaccatcgtggttctgtctgccaaataatcagccagccttgacagtc
gtccggcccggggacactgcccgggacaccctggagctgatctgtaagacacatcaactg
gatcactctgctcattacctgcgtctgaaatttctaatagaaaacaaaatgcaacactac
gttccaaagcccgaggaggacatttatgagctgctgtacaaagaaattgaaatttgtcca
aaagtcactcagaacatccagattgagaagtcagatacagccagtgataattatggcttt
tccctttcctctgtggaagaagatggcgttcgaaggctctatgtgaatagtgtaaaggaa
actggcttagcttccaagaaaggcctgaaagcgggagatgagattctcgagatcaatagc
cgggctgcaggcaccctgaactcctctgtgctcaaagatttcctcacgcagccgtccctg
ggcctcctggtgaggacctaccctgagctggttgggggtgtggagctgctggactgcccg
ccccaccgagcggacggccccgcggatctcaacgacagccccctggccttcctcagcagc
aacccagggcacggcctgtgcggcgagcagggcagtggtgctgagaccgctctggaggag
accgaagggccggacctggaatcctcagatgaaactgatcacagcagcaagagcacggaa
caggtggccgcattttgccgcagtctgcatgagatgaacctctctgacccgagcccatcg
cctcaggactccacagggcctcagctggccaccatgaggcagctcaccgacgctgacaag
ctgcgcaaggtcatctgtgagctcctggagacagagcgcacctatgtgaaagacttaaac
tgtctcatggagagatacctaaaacctcttcaaaaagaaactttcctcacccaagatgag
ctggacgtgctcttcggaaacctcaccgaaatggtagagtttcaggtagaatttctgaaa
accctggaggatggagtaagactggtccctgatttggaaaagctcgagaaagtcgatcaa
tttaagaaagtgctgttctccctggggggatcctttctgtattacgctgaccgcttcaag
ctctacagtgccttctgcgccagccacacgaaggtccccaaggtcctggtgaaagccaag
acggacacggctttcaaggcgttcttagatgcccagaacccgaaacagcagcactcggcc
actctcgagtcttacctcatcaagcccatccagaggatcctcaagtacccgctgctgctg
aaggagctctttgccctgacggatgccgagagcgaggagcactaccatctggacgtggcc
atcaagactatgaacaaggttgcaagtcatatcaatgaaatgcagaaaattcatgaagaa
tttggggctgtgtttgaccagctcattgctgaacagaccggtgagaaaaaagaggttgca
gatctgagcatgggggacctgcttttgcacaccaccgtgatttggccaaacccgccagcc
tccctgggaaagtggaaaaaggagccagaactggcagcctttgtcttcaaaactgctgtg
gtccttgtgtataaagacggttccaaacagaagaagaaacttgtaggatctcacaggctt
tcaatttatgaggactgggaccccttccggtttcggcacatgatccccaccgaagctctg
caggttcgagctttggcaagtgcagacgcggaagcaaatgccgtgtgtgaaattgtccat
gtaaagtctgagtctgaagggaggccggagaggatcttccacctgtgctgcagctctcca
gagagccggaaagatttcctgaaggctgtgcattcaatcctgcgtgataagcacagaaga
cagctcctcaaaactgaaagccttccctcatcccagcaatatgtaccttttggaggaaaa
agattgtgtgcgctcaaaggggccaggccagccatgagcagggcagtgtccgccccaagc
aagtctcttggcagaaggaggcggcgactggctcgaaacaggtttaccattgactctgat
gccatctcggccagcagcccggagaaagagtcccagcagccccccggtggcggggacact
gaccgatgggtagaggaacagttcgatcttgctcagtacgaggagcaagacgacatcaag
gagacagacatcctcagtgacgatgatgaattctgtgagtccgtgaagggcgccgcggtg
gacacagacctgcccgagcagcttcaggctgcgtccatcagtcagcgggagagaggccgc
aaaagcctggatagtcacgcgtcccgcatgacgcagctcaagaagcaagccgccctgtcg
ggcgtcaatggaggcctggagggcccgagcgaggaagtcatctgggttaggcgcgaagac
tttgccccctccaggaaactgaacactgagatctga

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