| Entry |
|
| Symbol |
TIAM1
|
| Name |
T-lymphoma invasion and metastasis-inducing protein 1
|
| Pathway |
| map04810 | Regulation of actin cytoskeleton |
|
| Disease |
| H02459 | Syndromic neurodevelopmental disorder |
|
| Brite |
KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
04015 Rap1 signaling pathway
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
04024 cAMP signaling pathway
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
09140 Cellular Processes
09144 Cellular community - eukaryotes
04530 Tight junction
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
09142 Cell motility
04810 Regulation of actin cytoskeleton
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
09150 Organismal Systems
09151 Immune system
04062 Chemokine signaling pathway
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
K05731 TIAM1; T-lymphoma invasion and metastasis-inducing protein 1
|
| Genes |
» show all
|
| Reference |
|
| Authors |
Minard ME, Kim LS, Price JE, Gallick GE |
| Title |
The role of the guanine nucleotide exchange factor Tiam1 in cellular migration, invasion, adhesion and tumor progression. |
| Journal |
|
| Reference |
|
| Authors |
Shepherd TR, Klaus SM, Liu X, Ramaswamy S, DeMali KA, Fuentes EJ |
| Title |
The Tiam1 PDZ domain couples to Syndecan1 and promotes cell-matrix adhesion. |
| Journal |
|
| Reference |
|
| Authors |
Habets GG, Scholtes EH, Zuydgeest D, van der Kammen RA, Stam JC, Berns A, Collard JG |
| Title |
Identification of an invasion-inducing gene, Tiam-1, that encodes a protein with homology to GDP-GTP exchangers for Rho-like proteins. |
| Journal |
|
| Sequence |
|
| LinkDB |
|