Prionailurus viverrinus (fishing cat): 125175018
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Entry
125175018 CDS
T09889
Symbol
BACE2
Name
(RefSeq) beta-secretase 2 isoform X1
KO
K07747
beta-site APP-cleaving enzyme 2 (memapsin 1) [EC:
3.4.23.45
]
Organism
pviv
Prionailurus viverrinus (fishing cat)
Pathway
pviv05010
Alzheimer disease
Brite
KEGG Orthology (KO) [BR:
pviv00001
]
09160 Human Diseases
09164 Neurodegenerative disease
05010 Alzheimer disease
125175018 (BACE2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01002 Peptidases and inhibitors [BR:
pviv01002
]
125175018 (BACE2)
Enzymes [BR:
pviv01000
]
3. Hydrolases
3.4 Acting on peptide bonds (peptidases)
3.4.23 Aspartic endopeptidases
3.4.23.45 memapsin 1
125175018 (BACE2)
Peptidases and inhibitors [BR:
pviv01002
]
Aspartic peptidases
Family A1: pepsin family
125175018 (BACE2)
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GFIT
Motif
Pfam:
Asp
TAXi_C
TAXi_N
Motif
Other DBs
NCBI-GeneID:
125175018
NCBI-ProteinID:
XP_047731229
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Position
C2:155254725..155356650
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AA seq
511 aa
AA seq
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MGAQARALLLPLLAHWLLRAAPAPAPAPLTLPLRVAAPTPGPGTPAAPRAAPRADGLALA
LEPAGGAANFLAMVDNLQGDSGRGYYLEMLIGTPPQKLQILVDTGSSNFAVAGAPHSYID
SYFDTERSSTYRSKGFDVTVKYTQGSWTGFVGEDVVTIPKGFNGSFLVNIATIFESENFF
LPGVKWNGILGLAYAALAKPSSSLETFFDSLVAQARIPNVFSMQMCGAGLPVAGSGTNGG
SLVLGGIEPSLYKGDIWYTPIKEEWYYQIEILKLEIGGQSLNLDCREYNADKAIVDSGTT
LLRLPQKVFDAVVEAVARTSLIPEFSDGFWTGSQLACWTNSETPWSYFPKISIYLRDENS
SRSFRLTILPQLYIQPMMGAGLNYECYRFGISPSTNALVIGATVMEGFYVVFDRARKRVG
FAASPCAEIAGAPVSEISGPFSTDDIASNCVPALPLNEPILWIVSYTLMSVCGIILLTLI
VLLLLPFRCRRLPPDPEVVNDESSLVRHRWK
NT seq
1536 nt
NT seq
+upstream
nt +downstream
nt
atgggcgcgcaggcccgggcgctgctgctgccgctgctggcccactggctcctgcgcgca
gccccggcgccggcccccgcacccctcacgctgcccctccgcgtggccgcgcccaccccc
gggcccgggacccccgccgcgccccgcgccgcgccccgagccgacggcctggcgctcgcc
ctggagcccgccggcggcgcggccaacttcttggccatggtggacaacctgcagggggac
tctggccgcggctactacctggagatgctgatcgggacccccccgcagaagctgcagatt
ctcgtggacactggaagcagcaacttcgccgtggcaggtgccccgcattcttacatagac
tcgtactttgacacggagaggtccagcacgtaccgctccaagggctttgacgtcactgtg
aagtacacgcaagggagctggacgggcttcgtgggggaggacgtggtcaccatcccgaaa
ggcttcaatggctcatttcttgtcaacattgccaccatcttcgaatccgagaacttcttt
ctgcccggcgtcaaatggaacgggattctgggactcgcgtatgctgccctggccaagccg
tcaagttccctggagacattctttgattctctggtggcacaagcgagaatccccaacgtc
ttctccatgcagatgtgtggggcgggactgcccgtcgctggatccggtaccaacggaggt
agtcttgtcctgggtggaattgaaccaagtttgtacaaaggagacatctggtatacccct
attaaggaggagtggtattaccagatagaaattctgaaattggaaattggaggccagagc
cttaatctggactgcagagagtacaatgcagacaaagccatcgtcgatagcggcaccaca
cttctgcgcctgccccagaaggtgtttgatgcggttgttgaagccgtggcccgcacgtct
ctgattccagaattctctgatggtttctggactgggtcccagctggcttgctggacgaat
tctgagacgccttggtcttacttccctaaaatctccatctacctgagagacgagaactcc
agccgatcgttccgcctaaccatcctgcctcagctttacatccagcccatgatgggggct
ggcctgaactacgaatgttaccgattcggcatttcaccttccaccaacgcgctggtgatc
ggtgctaccgtgatggagggcttctacgtggtctttgacagagctcggaagagggtgggc
tttgcggcaagcccctgcgcagagattgccggtgctccagtgtctgaaatttctgggcct
ttctcaacagacgacatagccagcaactgcgtccccgccctgcctttgaacgagcccatt
ttgtggattgtctcctacactctcatgagcgtgtgtggaatcatccttcttaccctgatc
gtcctgctgctacttcctttccggtgtcggcgcctgcccccggaccccgaggttgtcaat
gatgagtcctcgctcgtccggcatcgctggaaatga
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