Pteropus vampyrus (large flying fox): 105288850 Help Entry 105288850         CDS       T07815                                  Symbol ADCY5 Name (RefSeq) adenylate cyclase type 5   KO K08045   adenylate cyclase 5 [EC:4.6.1.1] Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp00230   Purine metabolism pvp01100   Metabolic pathways pvp01522   Endocrine resistance pvp04015   Rap1 signaling pathway pvp04022   cGMP-PKG signaling pathway pvp04024   cAMP signaling pathway pvp04062   Chemokine signaling pathway pvp04072   Phospholipase D signaling pathway pvp04081   Hormone signaling pvp04082   Neuroactive ligand signaling pvp04114   Oocyte meiosis pvp04211   Longevity regulating pathway pvp04213   Longevity regulating pathway - multiple species pvp04261   Adrenergic signaling in cardiomyocytes pvp04270   Vascular smooth muscle contraction pvp04371   Apelin signaling pathway pvp04540   Gap junction pvp04611   Platelet activation pvp04713   Circadian entrainment pvp04714   Thermogenesis pvp04723   Retrograde endocannabinoid signaling pvp04724   Glutamatergic synapse pvp04725   Cholinergic synapse pvp04726   Serotonergic synapse pvp04727   GABAergic synapse pvp04728   Dopaminergic synapse pvp04750   Inflammatory mediator regulation of TRP channels pvp04911   Insulin secretion pvp04912   GnRH signaling pathway pvp04913   Ovarian steroidogenesis pvp04914   Progesterone-mediated oocyte maturation pvp04915   Estrogen signaling pathway pvp04916   Melanogenesis pvp04918   Thyroid hormone synthesis pvp04921   Oxytocin signaling pathway pvp04923   Regulation of lipolysis in adipocytes pvp04924   Renin secretion pvp04925   Aldosterone synthesis and secretion pvp04926   Relaxin signaling pathway pvp04927   Cortisol synthesis and secretion pvp04928   Parathyroid hormone synthesis, secretion and action pvp04934   Cushing syndrome pvp04935   Growth hormone synthesis, secretion and action pvp04970   Salivary secretion pvp04971   Gastric acid secretion pvp04972   Pancreatic secretion pvp04976   Bile secretion pvp05012   Parkinson disease pvp05030   Cocaine addiction pvp05031   Amphetamine addiction pvp05032   Morphine addiction pvp05034   Alcoholism pvp05163   Human cytomegalovirus infection pvp05166   Human T-cell leukemia virus 1 infection pvp05200   Pathways in cancer pvp05207   Chemical carcinogenesis - receptor activation pvp05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pvp00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     105288850 (ADCY5)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     105288850 (ADCY5)    04371 Apelin signaling pathway     105288850 (ADCY5)    04072 Phospholipase D signaling pathway     105288850 (ADCY5)    04024 cAMP signaling pathway     105288850 (ADCY5)    04022 cGMP-PKG signaling pathway     105288850 (ADCY5)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     105288850 (ADCY5)    04081 Hormone signaling     105288850 (ADCY5)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     105288850 (ADCY5)   09144 Cellular community - eukaryotes    04540 Gap junction     105288850 (ADCY5)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     105288850 (ADCY5)    04062 Chemokine signaling pathway     105288850 (ADCY5)   09152 Endocrine system    04911 Insulin secretion     105288850 (ADCY5)    04923 Regulation of lipolysis in adipocytes     105288850 (ADCY5)    04912 GnRH signaling pathway     105288850 (ADCY5)    04913 Ovarian steroidogenesis     105288850 (ADCY5)    04915 Estrogen signaling pathway     105288850 (ADCY5)    04914 Progesterone-mediated oocyte maturation     105288850 (ADCY5)    04921 Oxytocin signaling pathway     105288850 (ADCY5)    04926 Relaxin signaling pathway     105288850 (ADCY5)    04935 Growth hormone synthesis, secretion and action     105288850 (ADCY5)    04918 Thyroid hormone synthesis     105288850 (ADCY5)    04928 Parathyroid hormone synthesis, secretion and action     105288850 (ADCY5)    04916 Melanogenesis     105288850 (ADCY5)    04924 Renin secretion     105288850 (ADCY5)    04925 Aldosterone synthesis and secretion     105288850 (ADCY5)    04927 Cortisol synthesis and secretion     105288850 (ADCY5)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     105288850 (ADCY5)    04270 Vascular smooth muscle contraction     105288850 (ADCY5)   09154 Digestive system    04970 Salivary secretion     105288850 (ADCY5)    04971 Gastric acid secretion     105288850 (ADCY5)    04972 Pancreatic secretion     105288850 (ADCY5)    04976 Bile secretion     105288850 (ADCY5)   09156 Nervous system    04724 Glutamatergic synapse     105288850 (ADCY5)    04727 GABAergic synapse     105288850 (ADCY5)    04725 Cholinergic synapse     105288850 (ADCY5)    04728 Dopaminergic synapse     105288850 (ADCY5)    04726 Serotonergic synapse     105288850 (ADCY5)    04723 Retrograde endocannabinoid signaling     105288850 (ADCY5)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     105288850 (ADCY5)   09149 Aging    04211 Longevity regulating pathway     105288850 (ADCY5)    04213 Longevity regulating pathway - multiple species     105288850 (ADCY5)   09159 Environmental adaptation    04713 Circadian entrainment     105288850 (ADCY5)    04714 Thermogenesis     105288850 (ADCY5)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105288850 (ADCY5)    05207 Chemical carcinogenesis - receptor activation     105288850 (ADCY5)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105288850 (ADCY5)    05163 Human cytomegalovirus infection     105288850 (ADCY5)   09164 Neurodegenerative disease    05012 Parkinson disease     105288850 (ADCY5)   09165 Substance dependence    05030 Cocaine addiction     105288850 (ADCY5)    05031 Amphetamine addiction     105288850 (ADCY5)    05032 Morphine addiction     105288850 (ADCY5)    05034 Alcoholism     105288850 (ADCY5)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     105288850 (ADCY5)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     105288850 (ADCY5)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     105288850 (ADCY5) Enzymes [BR:pvp01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      105288850 (ADCY5) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  AC_N Guanylate_cyc Adcy_cons_dom PEN-2 TBK1_ULD HILPDA GBR2_CC Motif Other DBs NCBI-GeneID:  105288850 NCBI-ProteinID:  XP_011353537 UniProt:  A0A6P3PXS4 LinkDB All DBs Position Unknown AA seq 1110 aa AA seqDB search MSGSKSVSPPGYAAQTAAAPASRGGPEHRSAWGEADARANGYPHAPGGSARGSTKRPGGA VTPQQQQRLASRWRSDDDDDPPLSGDDPLAGGFGFSFRSKSAWQERGGDDCGRGSRRHYL GVLAAAVGVILVMAVLCNRAAFHQDHMGLACYALIAVVLAVQVVGLLLPQPRSASEGIWW TVFFIYTIYTLLPVRMRAAVLSGVLLSALHLAIALRTNAQDQFLLKQLVSNVLIFSCTNI VGVCTHYPAEVSQRQAFQETRECIQARLHSQRENQQQERLLLSVLPRHVAMEMKADINAK QEDMMFHKIYIQKHDNVSILFADIEGFTSLASQCTAQELVMTLNELFARFDKLAAENHCL RIKILGDCYYCVSGLPEARADHAHCCVEMGMDMIEAISLVREVTGVNVNMRVGIHSGRVH CGVLGLRKWQFDVWSNDVTLANHMEAGGKAGRIHITKATLNYLNGDYEVEPGCGGERNAY LKEHSIETFLILRCTQKRKEEKAMIAKMNRQRTNSIGHNPPHWGAERPFYNHLGGNQVSK EMKRMGFEDPKDKNAQESANPEDEVDEFLGRAIDARSIDRLRSEHVRKFLLTFREPDLEK KYSKQVDDRFGAYVACASLVFLFICFVQITIVPHSMFMLSFYLTCFVLLTLVIFVSVIYS CVKLFPAPLQTLSRKIVRSKVNSTLVGVFTITLVFLAAFVNMFMCNSKDLFGCLADEHNI STSQVNACHVVESAFNYSLGDEQGFCGSPWPNCNFPEYFTYSVLLSLLACSVFLQISCIG KLVLMLAIELIYVLVVEVPGVTLFDNADLLVTANAIDFNNNGTSQCPEHATKVALKVVTP IVISVFVLALYLHAQQVESTARLDFLWKLQATEEKEEMEELQAYNRRLLHNILPKDVAAH FLARERRNDELYYQSCECVAVMFASIANFSEFYVELEANNEGVECLRLLNEIIADFDEII SEDRFRQLEKIKTIGSTYMAASGLNDSTYDKVGKTHIKALADFAMKLMDQMKYINEHSFN NFQMKIGLNIGPVVAGVIGARKPQYDIWGNTVNVASRMDSTGVPDRIQVTTDMYQVLAAN TYQLECRGVVKVKGKGEMMTYFLNGGPPLS NT seq 3333 nt NT seq  +upstreamnt  +downstreamnt atgtccggctccaaaagcgtgagccccccgggctacgcggcgcagacagccgcggcgcca gcgtcccggggaggcccggaacaccgctccgcgtggggagaggccgatgcccgcgccaat ggctacccccacgcccccggcggttcggcccgcggctccaccaagagacccgggggggcg gtgaccccgcagcagcagcagcgcctggccagccgctggcgcagcgacgacgacgacgac cctccgctgagtggcgacgaccccttggccgggggctttggcttcagcttccgctctaag tcagcctggcaggagcgcggcggcgacgactgcggacgcggcagccgccggcactacctg ggcgtgctggcggccgccgtgggcgtgatcctcgtcatggccgtgctctgcaaccgcgcc gcctttcaccaagaccacatgggcctggcctgctacgcgctcatcgcggtggtgctggcc gtccaggtggtgggcctgctgctgccccagccacgaagcgcctccgagggcatctggtgg acggtgttcttcatctacaccatctacacactgctacccgtgcgcatgcgggccgcagta ctcagcggggtgctcctgtctgccctccacctggccatcgccctgcgaaccaacgcccag gaccagttcctgctcaaacagctggtctccaatgtcctcattttctcctgcaccaacatt gtgggtgtctgcacccactatccggcagaggtctcccagagacaggccttccaggagacc cgggagtgtatccaggcacggctccactcacagcgggagaaccagcagcaggagcggctc ctgctgtctgtccttccccgtcatgttgccatggagatgaaagcagacatcaacgccaag caggaggatatgatgttccataagatttacatccagaaacatgacaatgtgagcatcctg tttgctgacattgagggcttcaccagcctggcatcccagtgcacggcccaagagctggtt atgaccctcaacgagctcttcgcccgcttcgacaagctggctgcggagaatcactgttta cgtattaagatcctgggggattgttattactgtgtctcggggctgcctgaagcgagggct gaccacgcccactgctgtgtggagatgggcatggacatgattgaggccatctcgttggtc cgggaggtgacaggggtgaacgtgaacatgcgcgtgggaattcacagcgggcgagtacac tgcggtgtccttggtctcaggaagtggcagttcgacgtctggtctaacgacgtcacgctg gccaaccacatggaggctggaggcaaggctggacgcatccacatcaccaaggccacactc aactacctgaatggagactacgaggtggagccgggctgtgggggcgagcgcaatgcctac ctcaaggagcacagcatcgagaccttcctcatcctgcgctgcacccagaagcggaaagaa gagaaggccatgatcgccaagatgaatcgccagagaaccaactccattgggcacaacccg ccgcactggggggctgagcgccccttctacaaccacttgggcggcaaccaggtgtccaag gagatgaagcggatgggcttcgaagaccccaaggacaagaatgcccaggaaagcgcgaac cccgaggatgaagtggatgaattcctgggccgagccatcgacgccaggagtattgacagg ctgcggtctgagcatgttcgcaagttcctcttgaccttcagggagcctgacttagagaag aagtactccaagcaggtggatgaccgattcggtgcctatgtggcgtgtgcctcgcttgtc ttcctcttcatttgctttgtccagatcaccatcgtgccccactccatgttcatgttgagt ttctacctgacctgtttcgtgctgctgaccttggtgatatttgtgtccgtcatctactcc tgtgtgaagctcttccccgcccctctgcagaccctctccaggaagatcgtgcggtccaag gtgaacagcaccctggttggggtgttcaccatcaccctggtgttcctggcagcatttgtc aacatgttcatgtgcaactccaaggacctattcggctgcctggcggatgagcacaacatc agcaccagccaggtcaacgcttgccacgtggtggagtcggccttcaactacagcctgggt gacgagcagggattctgtggcagcccctggcccaactgcaacttccctgagtacttcacc tacagcgtgctgctcagcctgctggcctgctccgtgttcctgcagatcagctgcatcggg aagctggtgctcatgctggccatcgagctcatatatgtgctcgtcgtcgaagtgcccggt gtcacactctttgacaatgcagacctgctagtcaccgccaacgccatagacttcaacaac aacgggacctcccagtgccctgagcacgcgaccaaagtggcgctgaaggtggtgacgccc attgtcatctcagtctttgtgctggccctgtacctgcacgcccagcaggtggagtccacc gcccgcctcgacttcctctggaaactgcaggccacggaggagaaggaggagatggaggag ctgcaggcctacaaccggcggctgctgcacaacatcctgcccaaggacgtggccgcccac ttcctggcccgtgagcggcgcaacgacgagctctactatcagtcgtgtgagtgcgtggcc gtcatgttcgcctccatcgctaacttctccgagttctatgtggagctggaggccaacaac gagggtgtcgagtgcttgcggctgcttaatgaaatcatcgccgatttcgacgagatcatc agcgaggatcggttcaggcagctggaaaagatcaagaccattggcagcacctacatggct gcctcaggcctcaatgattccacctatgacaaggtgggcaagacccacatcaaggctctg gccgacttcgccatgaagctgatggaccagatgaagtacatcaacgagcactccttcaac aacttccagatgaagattgggctcaatattggccccgtggtggccggggtgatcggggcc cgcaagcctcagtacgacatctggggcaatacggtgaatgtggccagccgcatggacagc acaggtgtgcctgaccgcatccaggtcaccacggacatgtatcaggtgctggctgccaac acataccagctggagtgccggggtgtggtcaaggtcaagggcaaaggcgagatgatgacc tacttcctcaatggagggcccccgctcagttag

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