Pteropus vampyrus (large flying fox): 105290574
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Entry
105290574 CDS
T07815
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp04064
NF-kappa B signaling pathway
pvp04380
Osteoclast differentiation
pvp04650
Natural killer cell mediated cytotoxicity
pvp04658
Th1 and Th2 cell differentiation
pvp04659
Th17 cell differentiation
pvp04660
T cell receptor signaling pathway
pvp05135
Yersinia infection
pvp05166
Human T-cell leukemia virus 1 infection
pvp05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pvp05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
105290574 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
105290574 (LCK)
04660 T cell receptor signaling pathway
105290574 (LCK)
04658 Th1 and Th2 cell differentiation
105290574 (LCK)
04659 Th17 cell differentiation
105290574 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
105290574 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
105290574 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
105290574 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
105290574 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
105290574 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pvp01001
]
105290574 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pvp03036
]
105290574 (LCK)
Enzymes [BR:
pvp01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
105290574 (LCK)
Protein kinases [BR:
pvp01001
]
Non-receptor tyrosine kinases
SRC family
105290574 (LCK)
Chromosome and associated proteins [BR:
pvp03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
105290574 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
SH2_1
Kdo
SH3_16
SH3_3
Motif
Other DBs
NCBI-GeneID:
105290574
NCBI-ProteinID:
XP_011356148
UniProt:
A0A6P3PYG2
LinkDB
All DBs
Position
Unknown
AA seq
526 aa
AA seq
DB search
MDCWGGGGMCVLIISGTMGCSCSSNPEDDWMENIDVCENCHYPIVSLDGKAKLPIRNGSE
VRDPLVTYEGSNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSL
TTGQEGFIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSF
SLSVRDFDQNQGEVVKHYKIRNLDKGGFYISPRITFPGLHELVRHYTNAPDGLCTRLSRP
CQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPD
AFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPAGIKLTINKLLD
MAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFP
IKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPD
NCPEELYHLMMLCWKERPEDRPTFDYLRSVLDDFFTATEGQYQPQP
NT seq
1581 nt
NT seq
+upstream
nt +downstream
nt
atggattgttgggggggagggggaatgtgtgtgctgataatctcagggaccatgggctgt
agctgcagctcaaaccctgaagatgactggatggaaaacatcgatgtatgtgagaactgc
cattaccctatagtctcactggatggcaaggccaagctgcccatcaggaatggctctgag
gtgcgggatccacttgttacctacgagggctccaaccccccagcttccccactgcaagac
aacctggttatcgccctgcacagctatgagccatctcatgatggagacctgggcttcgag
aagggtgaacaactgcgtatcctggagcagagtggcgagtggtggaaggcgcagtcgctg
accactggccaggaaggtttcatccccttcaacttcgttgccaaagcgaacagcctggag
cccgaaccctggttcttcaagaacctgagccgcaaggatgcagaacggcagctcctggcg
cccgggaacacgcacggctccttcctgatccgggagagcgagagcaccgcgggatcgttt
tccctgtccgtccgggatttcgatcagaaccagggagaggtggtgaaacattacaagatc
cgtaacttggacaaaggcggcttctacatctccccccgcatcacttttcctggcctgcac
gagctggtccgccattacaccaatgctccagacgggctatgcacgcggttaagccgcccc
tgccagacccagaagcctcagaagccgtggtgggaggacgaatgggaggttcccagggag
acgctgaagctggtggagcggctgggggctggccagttcggggaggtgtggatggggtac
tacaacgggcacacgaaggtggcagtgaagagcttgaagcagggcagcatgtcccctgac
gccttcctggcggaggccaacctcatgaagcagttgcaacaccagcggctggtccgtctc
tacgcggtggtcacccaggagcccatctacatcatcacggaatacatggagaacgggagc
ctggtggattttctcaagacccctgcaggtatcaaactgaccatcaacaaactcttggac
atggcagcccaaattgcagagggcatggcattcattgaagagcgcaattatatccaccgt
gacctgagggctgctaacatcctggtgtctgataccctgagctgcaaaatagcagacttt
ggactagcacgcctcatcgaggacaacgagtacacagccagggagggagccaagtttcca
attaagtggacagcaccagaagccattaactatgggaccttcactatcaagtcggacgtg
tggtcttttgggatactgttgacggagattgtcactcatggccgcatcccttacccaggg
atgaccaatcctgaggtgattcagaacctagagcgaggctaccgcatggtgagacctgac
aactgtccggaggagctgtaccacctcatgatgctgtgctggaaagagcgcccagaggac
cggcccacctttgactacctgcgcagtgtgctggatgacttcttcacggccacggagggc
cagtaccagccccagccctga
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