Pteropus vampyrus (large flying fox): 105293152 Help Entry 105293152         CDS       T07815                                  Symbol IL6 Name (RefSeq) interleukin-6 isoform X2   KO K05405   interleukin 6 Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp01521   EGFR tyrosine kinase inhibitor resistance pvp01523   Antifolate resistance pvp04060   Cytokine-cytokine receptor interaction pvp04061   Viral protein interaction with cytokine and cytokine receptor pvp04066   HIF-1 signaling pathway pvp04068   FoxO signaling pathway pvp04151   PI3K-Akt signaling pathway pvp04218   Cellular senescence pvp04620   Toll-like receptor signaling pathway pvp04621   NOD-like receptor signaling pathway pvp04623   Cytosolic DNA-sensing pathway pvp04625   C-type lectin receptor signaling pathway pvp04630   JAK-STAT signaling pathway pvp04640   Hematopoietic cell lineage pvp04657   IL-17 signaling pathway pvp04659   Th17 cell differentiation pvp04668   TNF signaling pathway pvp04672   Intestinal immune network for IgA production pvp04931   Insulin resistance pvp04932   Non-alcoholic fatty liver disease pvp04933   AGE-RAGE signaling pathway in diabetic complications pvp04936   Alcoholic liver disease pvp05010   Alzheimer disease pvp05020   Prion disease pvp05022   Pathways of neurodegeneration - multiple diseases pvp05132   Salmonella infection pvp05133   Pertussis pvp05134   Legionellosis pvp05135   Yersinia infection pvp05142   Chagas disease pvp05143   African trypanosomiasis pvp05144   Malaria pvp05146   Amoebiasis pvp05152   Tuberculosis pvp05161   Hepatitis B pvp05162   Measles pvp05163   Human cytomegalovirus infection pvp05164   Influenza A pvp05166   Human T-cell leukemia virus 1 infection pvp05167   Kaposi sarcoma-associated herpesvirus infection pvp05168   Herpes simplex virus 1 infection pvp05169   Epstein-Barr virus infection pvp05171   Coronavirus disease - COVID-19 pvp05200   Pathways in cancer pvp05202   Transcriptional misregulation in cancer pvp05321   Inflammatory bowel disease pvp05323   Rheumatoid arthritis pvp05332   Graft-versus-host disease pvp05410   Hypertrophic cardiomyopathy pvp05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pvp00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     105293152 (IL6)    04668 TNF signaling pathway     105293152 (IL6)    04066 HIF-1 signaling pathway     105293152 (IL6)    04068 FoxO signaling pathway     105293152 (IL6)    04151 PI3K-Akt signaling pathway     105293152 (IL6)   09133 Signaling molecules and interaction    04060 Cytokine-cytokine receptor interaction     105293152 (IL6)    04061 Viral protein interaction with cytokine and cytokine receptor     105293152 (IL6)  09140 Cellular Processes   09143 Cell growth and death    04218 Cellular senescence     105293152 (IL6)  09150 Organismal Systems   09151 Immune system    04640 Hematopoietic cell lineage     105293152 (IL6)    04620 Toll-like receptor signaling pathway     105293152 (IL6)    04621 NOD-like receptor signaling pathway     105293152 (IL6)    04623 Cytosolic DNA-sensing pathway     105293152 (IL6)    04625 C-type lectin receptor signaling pathway     105293152 (IL6)    04659 Th17 cell differentiation     105293152 (IL6)    04657 IL-17 signaling pathway     105293152 (IL6)    04672 Intestinal immune network for IgA production     105293152 (IL6)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105293152 (IL6)    05202 Transcriptional misregulation in cancer     105293152 (IL6)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     105293152 (IL6)    05161 Hepatitis B     105293152 (IL6)    05171 Coronavirus disease - COVID-19     105293152 (IL6)    05164 Influenza A     105293152 (IL6)    05162 Measles     105293152 (IL6)    05168 Herpes simplex virus 1 infection     105293152 (IL6)    05163 Human cytomegalovirus infection     105293152 (IL6)    05167 Kaposi sarcoma-associated herpesvirus infection     105293152 (IL6)    05169 Epstein-Barr virus infection     105293152 (IL6)   09171 Infectious disease: bacterial    05132 Salmonella infection     105293152 (IL6)    05135 Yersinia infection     105293152 (IL6)    05133 Pertussis     105293152 (IL6)    05134 Legionellosis     105293152 (IL6)    05152 Tuberculosis     105293152 (IL6)   09174 Infectious disease: parasitic    05146 Amoebiasis     105293152 (IL6)    05144 Malaria     105293152 (IL6)    05142 Chagas disease     105293152 (IL6)    05143 African trypanosomiasis     105293152 (IL6)   09163 Immune disease    05323 Rheumatoid arthritis     105293152 (IL6)    05321 Inflammatory bowel disease     105293152 (IL6)    05332 Graft-versus-host disease     105293152 (IL6)   09164 Neurodegenerative disease    05010 Alzheimer disease     105293152 (IL6)    05020 Prion disease     105293152 (IL6)    05022 Pathways of neurodegeneration - multiple diseases     105293152 (IL6)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105293152 (IL6)    05410 Hypertrophic cardiomyopathy     105293152 (IL6)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105293152 (IL6)    04932 Non-alcoholic fatty liver disease     105293152 (IL6)    04931 Insulin resistance     105293152 (IL6)    04933 AGE-RAGE signaling pathway in diabetic complications     105293152 (IL6)   09176 Drug resistance: antineoplastic    01521 EGFR tyrosine kinase inhibitor resistance     105293152 (IL6)    01523 Antifolate resistance     105293152 (IL6)  09180 Brite Hierarchies   09183 Protein families: signaling and cellular processes    04052 Cytokines and neuropeptides [BR:pvp04052]     105293152 (IL6) Cytokines and neuropeptides [BR:pvp04052]  Cytokines   Interleukins    105293152 (IL6) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  IL6 DUF4924 GCSF IL11 IL23 Motif Other DBs NCBI-GeneID:  105293152 NCBI-ProteinID:  XP_011359955 UniProt:  A0A6P3QB43 LinkDB All DBs Position Unknown AA seq 242 aa AA seqDB search MLDFFLAACGLESSHTAGGSYEHKLRKMPQGPPLTSHQRGAFRPVAFSLGLLLVMATAFP IPVPSGEDSKDDTNSNRPQLTSPNQTENLIKSIFLEISEVRNKMCGNDDSCKNSKEVLTE NNLNLPKMAEKDGCFQSGFNQETCLMKITTGLLEFQIYLDYLQNKFEENAKAMQMRTKAL VQVLKQKVKNPNEITTPDPTTNSSLLAKLQSQSEWLQTTTIHLILRSLEDFLQFTQRAVR IM NT seq 729 nt NT seq  +upstreamnt  +downstreamnt atgctagatttcttcctagccgcctgtggactcgaatcaagtcatacagcaggagggagc tatgaacacaagctccggaaaatgccacaaggtcctcctttgacatcccatcaaagaggc gctttcaggccagtcgccttctccctggggctgctgctagtgatggctactgctttccct attccggttccctccggagaagattccaaagatgataccaactcaaacagaccacaactc acctctccaaaccaaaccgaaaacctcattaagtccatcttccttgaaatctctgaagtg agaaataagatgtgtggcaacgatgactcatgtaaaaacagcaaggaggtactgacagaa aacaacctgaaccttccaaaaatggcagaaaaagatggatgcttccagtcggggttcaat caggagacctgcttgatgaaaatcactaccggtctcctggagtttcagatatacctggac tacctccagaacaagtttgaggaaaacgccaaggcgatgcagatgcgaaccaaagccctg gtccaggtgctgaagcagaaggtaaagaatccaaatgagataaccacccctgacccaacc acaaactccagcctgctggctaagctgcagtcgcagagcgaatggctgcagaccacgaca attcacctcatcctgcgaagccttgaggatttcctgcagttcacccagagggctgtccgg ataatgtag

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