Pteropus vampyrus (large flying fox): 105297298
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Entry
105297298 CDS
T07815
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp04010
MAPK signaling pathway
pvp04020
Calcium signaling pathway
pvp04022
cGMP-PKG signaling pathway
pvp04024
cAMP signaling pathway
pvp04260
Cardiac muscle contraction
pvp04261
Adrenergic signaling in cardiomyocytes
pvp04270
Vascular smooth muscle contraction
pvp04713
Circadian entrainment
pvp04720
Long-term potentiation
pvp04723
Retrograde endocannabinoid signaling
pvp04724
Glutamatergic synapse
pvp04725
Cholinergic synapse
pvp04726
Serotonergic synapse
pvp04727
GABAergic synapse
pvp04728
Dopaminergic synapse
pvp04742
Taste transduction
pvp04911
Insulin secretion
pvp04912
GnRH signaling pathway
pvp04921
Oxytocin signaling pathway
pvp04924
Renin secretion
pvp04925
Aldosterone synthesis and secretion
pvp04927
Cortisol synthesis and secretion
pvp04929
GnRH secretion
pvp04930
Type II diabetes mellitus
pvp04934
Cushing syndrome
pvp04935
Growth hormone synthesis, secretion and action
pvp05010
Alzheimer disease
pvp05020
Prion disease
pvp05022
Pathways of neurodegeneration - multiple diseases
pvp05031
Amphetamine addiction
pvp05207
Chemical carcinogenesis - receptor activation
pvp05410
Hypertrophic cardiomyopathy
pvp05412
Arrhythmogenic right ventricular cardiomyopathy
pvp05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
105297298 (CACNA1C)
04020 Calcium signaling pathway
105297298 (CACNA1C)
04024 cAMP signaling pathway
105297298 (CACNA1C)
04022 cGMP-PKG signaling pathway
105297298 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
105297298 (CACNA1C)
04929 GnRH secretion
105297298 (CACNA1C)
04912 GnRH signaling pathway
105297298 (CACNA1C)
04921 Oxytocin signaling pathway
105297298 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
105297298 (CACNA1C)
04924 Renin secretion
105297298 (CACNA1C)
04925 Aldosterone synthesis and secretion
105297298 (CACNA1C)
04927 Cortisol synthesis and secretion
105297298 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
105297298 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
105297298 (CACNA1C)
04270 Vascular smooth muscle contraction
105297298 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
105297298 (CACNA1C)
04727 GABAergic synapse
105297298 (CACNA1C)
04725 Cholinergic synapse
105297298 (CACNA1C)
04728 Dopaminergic synapse
105297298 (CACNA1C)
04726 Serotonergic synapse
105297298 (CACNA1C)
04720 Long-term potentiation
105297298 (CACNA1C)
04723 Retrograde endocannabinoid signaling
105297298 (CACNA1C)
09157 Sensory system
04742 Taste transduction
105297298 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
105297298 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
105297298 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
105297298 (CACNA1C)
05020 Prion disease
105297298 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
105297298 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
105297298 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
105297298 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
105297298 (CACNA1C)
05414 Dilated cardiomyopathy
105297298 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
105297298 (CACNA1C)
04934 Cushing syndrome
105297298 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pvp04040
]
105297298 (CACNA1C)
Ion channels [BR:
pvp04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
105297298 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
GPHH
Ca_chan_IQ
PKD_channel
CAC1F_C
Motif
Other DBs
NCBI-GeneID:
105297298
NCBI-ProteinID:
XP_023390961
UniProt:
A0A6P6CTS4
LinkDB
All DBs
Position
Unknown
AA seq
2127 aa
AA seq
DB search
MVNENTRMYIPEENHQGSSYGSPRPAHANMNANAAAGLAPEHIPTPGAALSWQAAIDAAR
QAKLMGSAGNATISTVSSTQRKRQQYGKPKKQGSTTATRPPRALLCLTLKNPIRRACISI
VEWKYPLPFEIIILLTIFANCVALAIYIPFPEDDSNATNSNLERVEYLFLIIFTVEAFLK
VIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFSAILEQATKADGANALGGKGAGFDVKALR
AFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLLHIALLVLFVIIIYAIIGLELFMGKMHKT
CYNQEGIADVPAEDDPSPCALETGHGRQCQNGTVCKPGWDGPKHGITNFDNFAFAMLTVF
QCITMEGWTDVLYWVNDAVGRDWPWIYFVTLIIIGSFFVLNLVLGVLSGEFSKEREKAKA
RGDFQKLREKQQLEEDLKGYLDWITQAEDIDPENEDEGMDEEKPRNMSMPTSETESVNTE
NVAGGDIEGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLN
TLTIASEHYNQPHWLTEVQDTANKALLALFTAEMLLKVYSLGLQAYFVSLFNRFDCFVVC
GGILETILVETKVMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLL
LFLFIIIFSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIM
AYGGPSFPGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKK
LARTASPEKKQEVIEKPAVEETKEEKIELKSITADGESPPTTKINMDDLQPNENEDKSAY
PNPETTGEEDDEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIV
NDTIFTNLILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNAD
YVFTSIFTLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIHKNTLKRLDLA
VTSRASPSYNEKNISYPWNDSSLRLPEVLLQPWHPRDVEAVGKLYTCSDSSKQTEAECKG
NYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRSIDSHTED
KGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDKNQGYFSD
PWNVFDFLIVIGSIIDVILSETNHYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSP
FMNAEENSRISITFFRLFRVMRLVKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFI
YAVIGMQVFGKIALNDTTEINRNNNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAP
ESEPSNSTEGETPCGSSFAVFYFISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHH
LDEFKRIWAEYDPEAKGRIKHLDVVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSD
GTVMFNATLFALVRTALRIKTEGNLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGGKCS
LISPHLALVRFLSPPGLQEACFPRTVPVALLMRRDKGATPFTNSDTGCQVRHLAQFCISQ
PSQRGPSGPLPLKLPGRLGEEFPICHVLPSVAVLSGEQTSLHTSAEERWLRGVPLHPPLP
SRLQRAGGLFGNHVVSYYQSDGRSAFPQTFTAQRPLHINKAGNSQGDTESPSHEKLVDST
FTPSSYSSTGSNANINNANNTALTRSPRPVGSPSAAGTTEGRGPPSSPAVRVQEAAWKLS
SKRCHSRESQIAMVCQEVSQEETYDVKMSDDAEYCSEPSLIATEMLSYQDDENRQLTPPE
EDKRDIRQSPKRGFLRSSSLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHHQALAVA
GLSPLLQRSHSPTTFRRPCATPPDTPGSRGWPPKPIPTLRLEGADSSENLNSSFPSIHCS
SWSGEPTPCGGASSATRKARPVSLTVPSQARAWGRQFHGSASSLVEAVLISEGLGQFAQD
PKFIEVTTQELADACDMTIEEMENAADNILSGGTQQSPNGTLLPFVNCRDPGQDRAGVEE
DEPCGPPQECRRGEEELQDSRAYVSGL
NT seq
6384 nt
NT seq
+upstream
nt +downstream
nt
atggtcaatgaaaacacgaggatgtacatcccagaggaaaaccaccaaggttccagctat
gggagcccacgcccagctcatgccaacatgaatgccaatgcagcggcagggcttgccccc
gagcacatccctactccaggggcggccctgtcctggcaggcagccatcgacgcggcccgg
caggccaagctgatgggaagtgctggcaatgcgaccatctccactgtcagctccacacag
cggaagcggcagcagtacgggaaacccaagaagcagggcagcacgaccgccacacgcccg
cctcgtgccctgctctgcctgactctgaagaaccccatccgcagggcgtgcataagcatt
gtcgaatggaaatatcctttaccatttgaaatcattattttactgactatttttgccaat
tgtgtggccttagcgatctatattccctttccagaagatgactccaatgccaccaattcc
aacctggaacgagtggaatatctctttctcatcatttttactgtggaagcatttttaaaa
gtaatagcctatggacttctctttcaccccaacgcttacctccgcaacggctggaattta
ctagattttataattgtggttgtagggctttttagtgcaattttagaacaagcaaccaaa
gctgatggggccaatgctctaggagggaaaggggctggatttgatgtgaaggctctgagg
gcgtttcgcgtgctgcgccccttgcggctggtgtccggagtcccgagtctccaggtggtc
ctgaattccatcatcaaggccatggtccccctgctgcatatcgccctgctagtgctgttt
gtcatcatcatctatgctatcatcggcctggagctcttcatggggaagatgcataagacc
tgctacaatcaggagggtatagcagatgttccagcagaagatgatccttccccttgtgct
ctggaaacaggccacgggcggcagtgccagaatggtactgtgtgcaagcccgggtgggac
gggcccaagcacggcatcaccaacttcgacaactttgccttcgccatgttgacagtgttc
cagtgcatcaccatggagggctggacagacgtgctgtactgggtcaatgatgccgtagga
agggactggccctggatctattttgttacacttatcatcatagggtcattttttgtactt
aacttggttctcggtgtccttagcggagagttttctaaagagagagagaaggccaaggct
cggggagatttccaaaagctgagagagaagcagcagctggaagaggatctgaaaggctac
ctggactggatcacccaagcagaagacatcgaccctgagaacgaggatgaaggcatggat
gaggagaaaccccgaaacatgagcatgcccacaagtgagacggagtctgtcaacactgag
aacgtggctggaggtgacatcgagggagaaaactgtggggccaggctggcccaccggatc
tccaagtcgaagttcagccgctactggcgccggtggaatcggttctgcagaagaaagtgt
cgcgccgcagtcaagtccaatgttttctattggctcgtgattttcctggtgttcctcaac
acgctcaccatcgcctcggagcattacaaccagcctcactggctcacagaagtccaagac
acagccaacaaggcactactggcccttttcacggcagagatgctgctgaaggtgtacagc
ctgggcttgcaggcctacttcgtgtccctgttcaaccgctttgactgcttcgtggtgtgc
gggggcatcctggagaccatcctggtggagaccaaggtcatgtctcccctgggcatctcc
gtgctcagatgcgtccgactactgaggatatttaaaatcacaaggtactggaactcctta
agcaacctggtggcatcgttgctgaactccgtgcgctccatcgcctccctgctgctgctt
ctcttcctcttcatcatcatcttctccctcctgggaatgcagctctttggaggaaagttc
aactttgatgagatgcagacccggaggagtacatttgataactttccccagtccctcctc
actgtgtttcagatcctgaccggggaggactggaattcggtgatgtatgatgggatcatg
gcttatggcggcccctcttttccagggatgttagtctgtatttacttcatcatcctcttc
atctgtggaaactatatcctactgaatgtgttcttggccattgctgtggacaacctggct
gatgctgagagcctcacatctgcccaaaaggaggaagaagaagagaaagagaggaagaag
cttgccaggactgccagcccagagaagaaacaagaggtgatagagaagccggcagtggag
gagaccaaggaggagaaaattgagctgaaatccattacagccgatggagagtccccaccc
accaccaagatcaacatggatgacctccagcccaatgaaaatgaggataagagtgcctac
cccaacccagaaactacaggagaagaggatgatgaggagcccgagatgcctgtgggcccc
cgcccacgaccactatctgagctgcaccttaaggaaaaagcagtgcccatgccagaagcc
agtgcatttttcatcttcagccccaacaacaggttccgcctccagtgccaccgcattgtc
aatgacacgatcttcaccaacctgatcctcttcttcattctgctcagcagcatttccctg
gccgctgaggaccctgtccagcacacgtccttcaggaaccatattctgttttattttgat
attgtttttactaccattttcaccattgaaattgctctgaagatcctaggcaatgcagac
tatgtcttcactagtatctttacattagaaattatccttaagatgactgcttatggggct
ttcttgcacaagggctccttttgccggaactacttcaacatcttggacctgctggtggtc
agcgtgtccctcatctcctttggcatccacaagaatacgttgaaacgtctggatctcgct
gtgaccagcagggccagccccagttataatgagaagaatatctcctacccctggaacgac
agcagcctgaggctcccagaagttctgctgcagccctggcatcctcgggatgtggaggct
gttggaaagctctacacctgttcagacagttccaagcagacagaggcagaatgcaagggt
aactacatcacgtacaaggacggagaggttgaccaccccatcatccagcctcgcagctgg
gagaacagcaagttcgactttgacaatgttctggcagccatgatggccctcttcactgtc
tccacctttgaggggtggccagagctgctgtaccgctccatcgactcccacacggaggac
aagggccccatctacaactaccgcgtggagatctccatcttcttcatcatctacatcatc
atcattgccttcttcatgatgaacatcttcgtgggtttcgtcatcgtcaccttccaggag
cagggagagcaggagtacaagaactgtgagctggacaagaaccagggttactttagtgat
ccctggaatgtttttgacttcctcatcgtaattggcagcataattgacgtcattctcagt
gaaactaatcactatttctgtgatgcatggaatacatttgacgccttgattgttgtgggt
agcattgttgatatagcaatcaccgaggtaaacccagctgaacacacccaatgctctccc
tttatgaatgcagaggagaactcccgcatctccatcactttcttccgcctcttccgtgtc
atgcgcctggtcaagctgctgagccgcggggagggcatccggaccttgctgtggaccttc
atcaagtccttccaggccctgccctacgtggcccttctgatagtgatgctcttcttcatt
tacgcagtgatcgggatgcaggtgtttgggaaaattgccctgaatgacaccacagagatc
aaccggaataacaactttcagaccttcccccaagctgtgctgctcctcttcaggtgtgcc
accggggaggcgtggcaggacatcatgttggcttgcatgccagggaagaagtgtgcccca
gagtcggagcccagcaacagcacagaaggggagacgccctgtggcagcagcttcgccgtc
ttctacttcatcagcttctacatgctctgtgccttcctgatcatcaacctctttgtagct
gtcatcatggacaactttgactacctgacaagggactggtcaatccttggtccccaccat
ctggatgaatttaaaagaatctgggcagagtatgaccctgaagccaagggtcgtatcaaa
cacctagacgtggtgaccctgctccggcggattcagcccccattgggttttgggaagctg
tgccctcaccgtgtggcttgcaaacgcctggtctccatgaacatgcctctgaacagcgat
gggacagtcatgttcaatgccaccctgtttgccctggtccggacagccctaaggatcaaa
acagaagggaacctggaacaagccaatgaggagttgcgagccataatcaagaagatctgg
aagcggaccagcatgaagctgctggaccaggtggtgccccccgcaggcggtaagtgctcc
ctgatctccccacacttggcgcttgtccggttcttgagtcctccaggcttgcaagaagcc
tgcttcccccggaccgtacccgtggccctactgatgaggagggacaagggtgccacgccc
ttcacaaactcagatacaggctgtcaggttagacatctggcccagttctgcatttcacag
ccctcccagaggggaccgtctgggcccctgcctcttaagctgccaggccgcttgggtgaa
gaattccccatctgccacgtgctgcccagcgtggctgtgctctcgggagagcagacaagc
ctccacacctcagccgaggagaggtggctgaggggcgttcccctccacccacccctgccc
tctcgcctgcagagggccggtggcctgtttggcaaccacgtcgtcagctactaccaaagc
gacggccggagcgccttcccccagaccttcaccgcccaacgcccgctgcacatcaacaag
gcgggtaacagccaaggcgacaccgagtcgccatcccacgagaaactggtggactccacc
ttcacccccagcagctactcatccactggctccaacgccaacatcaacaacgccaacaac
accgccctgacccgctcccctcgccccgtcggctcccccagcgcagccggcactacggag
ggccgcgggcccccctcgtctcctgctgtccgggtgcaggaggcagcgtggaagctcagc
tccaagaggtgccactcccgggagagccagatagccatggtgtgtcaggaggtctcccag
gaagagacgtacgatgtgaagatgagtgacgatgccgagtactgcagcgagcccagcctg
atcgccacagagatgctctcctatcaggatgatgaaaaccgacagttgacaccccctgag
gaggacaagagggacatccggcaatctccaaagaggggtttcctccgctcgtcctcccta
ggtcgaagggcctccttccatctggaatgtctgaagcgacagaagaatcaagggggagac
atctctcagaagacagttctgcccttgcatctggtccatcatcaggcgttggccgtggca
ggcctgagcccactcctccagagaagccattcccccaccacgttccgcagaccatgtgcc
acccctccagacacgcccggcagccgaggctggcccccaaagcccatccccaccctgcgg
ctggaaggagccgactccagcgagaatctcaacagcagcttcccatccatccactgcagc
tcctggtctggggagcccacgccctgtgggggggccagcagtgccacccggaaagcccgg
cctgtgtccctcactgtgcccagccaggccagagcctggggcaggcagttccatggcagt
gccagcagtctggtagaagcggtcttgatttcagaaggactggggcagtttgctcaagat
cccaaattcatcgaagtcacaacccaggagctagctgatgcctgcgacatgaccatagag
gagatggagaatgctgctgacaacatcctcagtgggggcacccagcagagccccaacggc
accctattaccttttgttaactgcagggacccggggcaggacagagcaggggtagaagag
gacgagccctgtgggcccccgcaggagtgtcgaaggggcgaggaggagctgcaggacagc
cgagcctacgtcagcggcctgtag
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integrated database retrieval system
