Pteropus vampyrus (large flying fox): 105298127 Help Entry 105298127         CDS       T07815                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp01524   Platinum drug resistance pvp04115   p53 signaling pathway pvp04210   Apoptosis pvp04215   Apoptosis - multiple species pvp04217   Necroptosis pvp04620   Toll-like receptor signaling pathway pvp04621   NOD-like receptor signaling pathway pvp04622   RIG-I-like receptor signaling pathway pvp04623   Cytosolic DNA-sensing pathway pvp04625   C-type lectin receptor signaling pathway pvp04657   IL-17 signaling pathway pvp04668   TNF signaling pathway pvp04932   Non-alcoholic fatty liver disease pvp04936   Alcoholic liver disease pvp05010   Alzheimer disease pvp05016   Huntington disease pvp05022   Pathways of neurodegeneration - multiple diseases pvp05132   Salmonella infection pvp05134   Legionellosis pvp05142   Chagas disease pvp05145   Toxoplasmosis pvp05152   Tuberculosis pvp05160   Hepatitis C pvp05161   Hepatitis B pvp05162   Measles pvp05163   Human cytomegalovirus infection pvp05164   Influenza A pvp05165   Human papillomavirus infection pvp05167   Kaposi sarcoma-associated herpesvirus infection pvp05168   Herpes simplex virus 1 infection pvp05169   Epstein-Barr virus infection pvp05170   Human immunodeficiency virus 1 infection pvp05200   Pathways in cancer pvp05203   Viral carcinogenesis pvp05416   Viral myocarditis pvp05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pvp00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     105298127 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     105298127 (CASP8)    04215 Apoptosis - multiple species     105298127 (CASP8)    04217 Necroptosis     105298127 (CASP8)    04115 p53 signaling pathway     105298127 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     105298127 (CASP8)    04621 NOD-like receptor signaling pathway     105298127 (CASP8)    04622 RIG-I-like receptor signaling pathway     105298127 (CASP8)    04623 Cytosolic DNA-sensing pathway     105298127 (CASP8)    04625 C-type lectin receptor signaling pathway     105298127 (CASP8)    04657 IL-17 signaling pathway     105298127 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     105298127 (CASP8)    05203 Viral carcinogenesis     105298127 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     105298127 (CASP8)    05161 Hepatitis B     105298127 (CASP8)    05160 Hepatitis C     105298127 (CASP8)    05164 Influenza A     105298127 (CASP8)    05162 Measles     105298127 (CASP8)    05168 Herpes simplex virus 1 infection     105298127 (CASP8)    05163 Human cytomegalovirus infection     105298127 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     105298127 (CASP8)    05169 Epstein-Barr virus infection     105298127 (CASP8)    05165 Human papillomavirus infection     105298127 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     105298127 (CASP8)    05134 Legionellosis     105298127 (CASP8)    05152 Tuberculosis     105298127 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     105298127 (CASP8)    05142 Chagas disease     105298127 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     105298127 (CASP8)    05016 Huntington disease     105298127 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     105298127 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     105298127 (CASP8)    05416 Viral myocarditis     105298127 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     105298127 (CASP8)    04932 Non-alcoholic fatty liver disease     105298127 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     105298127 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pvp01002]     105298127 (CASP8) Enzymes [BR:pvp01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      105298127 (CASP8) Peptidases and inhibitors [BR:pvp01002]  Cysteine peptidases   Family C14: caspase family    105298127 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED COG6_N PYRIN Motif Other DBs NCBI-GeneID:  105298127 NCBI-ProteinID:  XP_011367462 UniProt:  A0A6P3QR21 LinkDB All DBs Position Unknown AA seq 484 aa AA seqDB search MSFNSCLYDIGENLGSDELASLKFLSLDYIPQRKQEPIKDALTLFQRLLEKRMLEESNLS FLKELLFRINRLDLLVNHLDTSGEEMKKELQIPGKAQISAYRVMLFQISEDVSKPELKAF KFLLSQEIAKCKLEDDMTLLDIFIEMEKRLILGKRNLDTLKRICDQVNKSLLKKISDYEE LSRDVSQSCAGELSLEMLSMSDSPGEQDCESQEQGSESEDTESQQTSDKVYRMKSKPRGY CVIFNNYDFSEARKAVPKLHSIKDRNGTDLDAGALSETFKDLHFEINTFKNCTAKEICDV LKSYQSRNHNNKDCFICCILSHGDKGIIYGCDGQEVPIYELTSYFTGSNCPSLLDKPKIF FIQACQGDNYQRGIPVETDSEEKETYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNP MEGTWYIQSLCQSLREKCPRGEDILTILTDVNFEVSRKDDKKNMGKQMPQPTFTLRKKLF FPLN NT seq 1455 nt NT seq  +upstreamnt  +downstreamnt atgagtttcaacagttgtctctatgatattggagaaaatctgggcagtgatgagctggcc tccctcaagttcctgagcctggactacatcccacaaaggaagcaggaacccatcaaggat gccttaacattgttccagagactcctggaaaagagaatgttggaggaaagcaacttgtcc ttcttgaaggagctgctattccgaattaatagactggatttgctggtcaaccacctagac accagcggagaagagatgaagaaggagctgcagataccgggcaaggctcagatctctgcc tacagggtcatgctttttcagatttcggaagatgtaagcaaaccggaattgaaggccttt aagtttcttttgagccaggagatcgccaaatgtaaactggaagatgacatgaccttgctt gatattttcatagagatggagaagaggcttatacttgggaaaagaaatctggacactctg aaaagaatctgtgaccaagtcaacaagagcctgctgaagaaaatcagtgattatgaagaa ttaagcagagatgtgtctcaatcgtgtgcaggggagttgtcattggagatgctatcaatg tcggactctcccggagaacaggactgtgaatcacaagaacagggcagtgagtcagaagac accgagtcacaacagacatcggacaaagtttaccgaatgaaaagcaagcctcgtgggtac tgtgtgatatttaacaattatgattttagcgaagcacggaaggctgtgcccaaacttcac agcatcaaggatagaaatggaacagacttggatgcaggggctttgagtgaaacctttaaa gaccttcattttgagataaatactttcaaaaactgcacagcaaaggaaatctgtgatgtt ctgaaatcctatcaaagcagaaaccacaataacaaggactgcttcatctgttgcatcctc tcccatggagacaagggcatcatctatggctgtgatgggcaggaagtccctatctatgag ctgacttcttacttcactggttcaaattgcccttccctcctagacaaacccaaaatcttt tttattcaggcttgtcaaggggataactaccagagaggtatacctgttgagactgactca gaagagaaggaaacctatttagaaatggattcatcatttcagaagagatatatccctgat gaggccgactttctgctagggatggccactgtgaacaactgtgtttcctaccgaaacccc atggaggggacctggtatattcagtcactctgtcagagcctgagagaaaaatgtcctagg ggtgaagatattcttaccatcctcactgatgtgaactttgaagtgagcagaaaggatgac aagaaaaatatggggaagcagatgccacaacctaccttcaccctgagaaaaaaactcttt ttccctctgaattga

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