Pteropus vampyrus (large flying fox): 105300302
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Entry
105300302 CDS
T07815
Symbol
HSD11B1
Name
(RefSeq) corticosteroid 11-beta-dehydrogenase isozyme 1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp00140
Steroid hormone biosynthesis
pvp00980
Metabolism of xenobiotics by cytochrome P450
pvp01100
Metabolic pathways
pvp05204
Chemical carcinogenesis - DNA adducts
Module
pvp_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
105300302 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
105300302 (HSD11B1)
09160 Human Diseases
09161 Cancer: overview
05204 Chemical carcinogenesis - DNA adducts
105300302 (HSD11B1)
Enzymes [BR:
pvp01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
105300302 (HSD11B1)
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Ortholog
Paralog
GFIT
Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
THF_DHG_CYH_C
Shikimate_DH
2-Hacid_dh_C
Pyr_redox_3
Pyr_redox_2
NAD_binding_2
AdoHcyase_NAD
Motif
Other DBs
NCBI-GeneID:
105300302
NCBI-ProteinID:
XP_011370750
UniProt:
A0A6P3QXL9
LinkDB
All DBs
Position
Unknown
AA seq
296 aa
AA seq
DB search
MAFVKNYLFPILGIFLAYYYYSASEEFRPEMLQGKKVIVTGASKGIGKEMAYHLAKMGAH
VMVTARSEETLKKVVSHCLELGAASAHYLAGTMENMTFAEQFVAKTGQLMGGLDMLILNH
ITYVPLQLFRDDVRLVRDSMEVNFLSYVVLSVAALPMLKQSNGSIVVVSSVAGKISNPLI
APYAASKFALDGFFSSIRKEYSMAKVNVSITLCILGLINTDTAMKAVSGILNSDASPKEE
CALEIIKGGALRQEEVYYDRSVWTSLLLKNPGRKILEFFSHRSYNMDRFIKNEELP
NT seq
891 nt
NT seq
+upstream
nt +downstream
nt
atggcttttgtgaaaaactatctgttccctattctggggatcttcttggcctactactac
tattctgcaagtgaggaattcagaccagagatgctccaaggaaagaaagtgattgtcaca
ggggccagcaaggggatcggaaaagagatggcctatcatctggcgaagatgggagcccat
gtgatggtgacagcaaggtcagaagaaactctaaagaaggtggtatctcactgcctagaa
cttggagcagcctcggcacactaccttgctggcaccatggagaacatgacctttgcggaa
caatttgttgccaaaactggacagctcatgggaggactagacatgctcattctcaaccac
atcacctacgttcctctgcaactctttcgtgatgacgtccgtctcgtgcgtgacagcatg
gaggtcaacttcctcagttacgtggtcttgagtgtggctgccctgcccatgctgaagcag
agcaacggcagcatcgtcgtcgtctcctcggtggctgggaaaatatctaatccacttatt
gctccctatgctgcaagcaagtttgctctggatgggtttttctcctccatcaggaaggaa
tattcaatggccaaggtcaatgtgtcaatcactctctgtatcctcggcctcataaacacg
gacaccgccatgaaggcagtttctggaatactcaacagtgatgcatctccaaaggaagaa
tgtgccttggagattatcaaagggggagctctgcgccaagaggaagtgtattatgacaga
tcggtatggacctctctcctgctgaaaaatccagggaggaagatcctggaatttttctcc
cacagaagttataatatggacagatttataaaaaatgaggaacttccttag
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