Pteropus vampyrus (large flying fox): 105301327
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Entry
105301327 CDS
T07815
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2 isoform X1
KO
K07187
insulin receptor substrate 2
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp04022
cGMP-PKG signaling pathway
pvp04068
FoxO signaling pathway
pvp04081
Hormone signaling
pvp04140
Autophagy - animal
pvp04152
AMPK signaling pathway
pvp04211
Longevity regulating pathway
pvp04213
Longevity regulating pathway - multiple species
pvp04910
Insulin signaling pathway
pvp04920
Adipocytokine signaling pathway
pvp04923
Regulation of lipolysis in adipocytes
pvp04930
Type II diabetes mellitus
pvp04931
Insulin resistance
pvp04932
Non-alcoholic fatty liver disease
pvp04935
Growth hormone synthesis, secretion and action
pvp05010
Alzheimer disease
pvp05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
105301327 (IRS2)
04022 cGMP-PKG signaling pathway
105301327 (IRS2)
04152 AMPK signaling pathway
105301327 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
105301327 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
105301327 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
105301327 (IRS2)
04923 Regulation of lipolysis in adipocytes
105301327 (IRS2)
04920 Adipocytokine signaling pathway
105301327 (IRS2)
04935 Growth hormone synthesis, secretion and action
105301327 (IRS2)
09149 Aging
04211 Longevity regulating pathway
105301327 (IRS2)
04213 Longevity regulating pathway - multiple species
105301327 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
105301327 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
105301327 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
105301327 (IRS2)
04932 Non-alcoholic fatty liver disease
105301327 (IRS2)
04931 Insulin resistance
105301327 (IRS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
105301327
NCBI-ProteinID:
XP_011372230
UniProt:
A0A6P3QYZ6
LinkDB
All DBs
Position
Unknown
AA seq
1407 aa
AA seq
DB search
MASPPLQGPPGLAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAVGDEA
TATAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVISLDCCLNINKRADAKHKYLIALYTK
DEYFAVAAENEQEQEGWYRALTDLVSEGRAVAGDAPSSAATAGSCSASLPGALGGSAGAD
DSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ
LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR
PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV
RTASEGDGGAATGTGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGSRASKVTLTPA
GGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHPLQHHAGQRP
SSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGSELYGY
MTMDRPLSHCGRPYRRVSGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMR
ATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGVAL
MGGGSGSCKSDDYMPMSPTSVSAPKQILQPRAAAAALPPTGAAVPAPASVASRAFPVNGA
SYKASSPAESSPEDSGYMRMWCGSKLTMENTDSKLLPNGDYLNMSPSDAGTSETPPDDFS
AALHSGGEMLRGIPGYCYSSLPRSYKAPYTCSGDNDQYVLMSSPVGRILEEERPEPQASA
GTTQSASVFVAGMGGGSHTQLPHSVVPSPGRLSGSGCGRPEGFLNQRCRAVRPTRLSLEG
LQTLPRMHEYPLPPEPKSPGEYINIDFSETGARLSPPAPPLLASAASSSSLLSASSPASS
LGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPSTQSGDPVGSLDALLSPEASSQYPPL
PPRPAAPSSSLQPQPPPPPPPGELYRLPPASTSQGPSAASSSSSETGDNGDYTEMAFGVA
ATPPQPIVAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADP
QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKNSEGGGSGILGGGDEP
SSSPHQLQPPLPQQARAWTPNQPGGLVGCPGSSGSPMRRETSAGFQNGLNYIAIDVRDEP
GLLSPQQQHPHSQQHPHSQSGDKSTWGRTRSLGGLISAVGANSTGGVCGGPGPGALPSAN
TYASIDFLSHHLKEATIVKDTHDLPRKAPLSCAEEASWPSAAPSTHNASCSENLPLLDPL
PSATVAAVVGGGQSHLAGQLCVSNPSG
NT seq
4224 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcaggggccccccgggttggcgggcggcgacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaagcgcttcttcgtgctgcgcggccccggcgcggttggcgacgaggca
actgccacagcgggcgggggtccggcgccgcagccgccgcggctcgagtactacgagagc
gagaagaagtggcggagcaaggctggcgccccgaagcgggtcatctcgcttgactgctgc
ttgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaag
gacgagtacttcgccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcg
ctcaccgacctggtcagcgagggccgcgcggttgccggcgacgcgccctcctccgccgcc
actgccgggtcctgcagcgcctctttgcctggcgccctgggcggctcggccggcgctgat
gacagctacgggctggtggcgcccgccacagccgcctaccgcgaggtgtggcaggtgaac
ctgaagcccaagggcctgggtcagagcaaaaacctgacgggcgtgtaccgcctttgcctg
tcggcgcgcaccatcggcttcgtgaagctcaactgcgaacagccgtcggtgactctgcaa
ctcatgaacattcgccgctgcggccactcggacagtttcttcttcatcgaggttggccgc
tcagctgtcaccggccccggcgagctgtggatgcaggccgacgactcggtggtggcgcag
aacatccatgagaccatcctagaggccatgaaggcgctcaaggagctctttgagttccgg
ccgcgcagcaagagccagtcgtcgggatcatcagccacgcaccccattagcgtccccggc
gcgcgccgtcaccaccacctggtcaacctgccccccagccagacgggcttggtgcggcgc
tcgcgcaccgacagcctggctgccaccccgccggccgccaaatgtagctcctgccgggtg
cgcacggccagcgagggcgacggcggcgcagcgacggggactggggcggcgggcggcagg
cccgtgtcggtggcggggagccccctgagtcccgggcccgtgcgcgcgccgcttagtcgt
tcgcataccctgagcggcggctgcggcagccgcgcgagcaaggtaacgctgacgccggca
gggggcgccctgcagcacagccgctcgatgtccatgcccgtggctcactcgccccctgcc
gctaccagccccggaagcctgtcttccagcagtgggcacggctcgggctcctacccgccg
cctccgggcccgcacccacacctacagcaccccttgcagcaccacgcgggccagcggcct
tccagcggcagcgcctcagcctccggctcccccagcgatcccggctttatgtctctggat
gagtacggctccagccctggggacctgagagccttctgtagccacaggagcaacactcct
gagtccatcgccgagacacctccggccagggacggcagcgggagtgagctgtacggctac
atgaccatggacaggcccctgagccactgtggccgcccctaccgtcgtgtctcaggggac
ggagctcaggacttggacagagggctaaggaagaggacttactccctgaccacacctgcc
cggcagcgaccggtgccccagccctcctcagcgtccctggatgaatacaccctgatgcgg
gccaccttctctggcagctcgggccgcctctgcccgtcctgccctgcgtcttctcccaaa
gtggcctaccacccctatcctgaggactacggcgacattgagattgggtcccataggagc
tccagcagtaacctgggcacggacgatggttacatgcccatgacccctggcgtggccctc
atgggtggtggcagtggcagctgcaagagtgatgactacatgcccatgagtcccaccagc
gtgtctgccccaaagcagatcttgcagccacgggctgctgcagcagccttgccccccaca
ggagctgcagtgccagcgccggcctctgtggccagcagggcctttccagtgaacggggcc
agctacaaggccagctccccggccgagagctctcccgaagacagtggatacatgcgcatg
tggtgtggttccaagctgaccatggagaatacagacagcaagctgcttcccaacggggac
tacctcaacatgtcccccagcgatgcaggcacctcggaaaccccaccagatgacttctca
gcagccttgcatagcggtggggagatgctcaggggcattcctggctactgctacagctct
ttgccccgctcctataaggctccttacacctgtagtggggacaatgaccagtacgtactc
atgagctccccggtggggcgcatcctagaagaggagaggccagagccacaggccagcgca
gggaccacgcagtcggccagcgtcttcgtggctgggatgggtgggggcagccacacccag
cttcctcactccgtagtgccttcgcctgggaggctgagtggcagcggctgtggccgccca
gagggtttcctgaaccaacgctgtcgggcagtgcgacccacgcgcctgtccctggagggg
cttcagaccctacccaggatgcacgagtatcctctgccgccggaacccaagagcccgggc
gaatacatcaacattgactttagcgaaaccggagcgcgcttgtcaccgcctgcccctccg
ctgctggcttccgctgcctcgtcctcctcgctgctgtctgccagcagcccagcctcatcc
ctgggctctggtactccgggcacaagcagcgacagccggcagcgctccccgctctccgac
tacatgaacctcgatttcagttcgcccaagtcacccaaaccgagtacccagagcggtgac
ccggtggggtccttggatgccctcctgtctcctgaggcctcctcccagtacccgccactg
cctcctcgccctgctgccccctcctcctccttgcagccgcagccgcctcccccacctccc
ccaggggagctgtaccgcctgcctccagcatccacatcccagggccccagcgctgcctcc
tcttcgtcctcggagactggggacaatggtgactacaccgagatggcctttggcgtagct
gccaccccgccacaacccatcgtggcccccccgaagccggaaggtgcccgtgtgaccagc
cccacgtccggcctgaagaggctgagtctcatggatcaggtgtctggagtggaggccttt
ttgcaggctggccagcccccagacccacaccggggggccaaggtcatccgggcagacccg
caggggggccgccgccgccacagttccgagaccttttcctcgaccaccactgtgaccccc
gtgtccccatccttcgcccacaacccgaagcgccacaactcggcctccgtggaaaacgtc
tctctcaggaaaaacagcgaaggaggtggcagtggcatccttggtgggggcgacgaacct
tcctcttccccccaccagttgcaaccacccctcccccagcaggcacgggcatggacaccg
aatcagcctgggggtctggttggctgccctgggagcagtggctctcctatgcgcagggag
acctctgccggcttccagaatggcctcaactacatcgccatcgatgtgagagatgagcca
gggctgttgtctccccaacaacaacacccgcattcgcagcaacatccacattcgcagtcg
ggcgacaagagcacttggggccggacccgtagcctcgggggtctcatcagcgctgtgggg
gccaacagcaccggtggagtgtgtggggggcccggccctggcgccctaccctcagccaac
acctatgccagcattgacttcttgtcccatcacctgaaggaggccaccattgtgaaagac
acccatgatctacccagaaaagcccccctctcctgtgcagaggaggcctcctggccatca
gcagccccctccacccataatgcctcctgctctgagaacctgcctctgctggaccccctg
ccctccgccacagtggctgctgttgtcgggggagggcagtcccacttggctgggcagctc
tgtgtttccaacccatcaggctga
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integrated database retrieval system
