Pteropus vampyrus (large flying fox): 105304290
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Entry
105304290 CDS
T07815
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pvp
Pteropus vampyrus (large flying fox)
Pathway
pvp04120
Ubiquitin mediated proteolysis
pvp04144
Endocytosis
pvp04330
Notch signaling pathway
pvp04668
TNF signaling pathway
pvp04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
pvp00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
105304290 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
105304290 (ITCH)
04668 TNF signaling pathway
105304290 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
105304290 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
105304290 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pvp04131
]
105304290 (ITCH)
04121 Ubiquitin system [BR:
pvp04121
]
105304290 (ITCH)
Enzymes [BR:
pvp01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
105304290 (ITCH)
Membrane trafficking [BR:
pvp04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
105304290 (ITCH)
Ubiquitin system [BR:
pvp04121
]
Ubiquitin ligases (E3)
HECT type E3
105304290 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
105304290
NCBI-ProteinID:
XP_011376589
UniProt:
A0A6P6BS98
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGLELDSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVAVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLVGDKEPTETIGDLSVCLDGLQLETEVVTNGETTCSESASQNDDGSRPKDETRVNTNGS
DDPEDAGPGENRRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRMDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKFQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggattagagcttgattcaatgggtagcctgaccatgaaatcacaactt
cagatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttggaccaagt
ccttatgtggaagttgcagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttattgtcactcctgtaagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgtaggtgacaaagagccaacagaaacaataggagacttgtcagtttgtcttgat
gggctacagttagagactgaagttgttaccaacggtgaaacgacatgttcagaaagtgct
tcacagaatgatgatggttccagacctaaggatgaaacaagagtgaacacaaatggatca
gatgaccctgaggatgcagggcctggtgaaaataggagagtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccttctgccacttctgaaagtgat
ggatctagtacaggttctctgccgccaacaaatacaaattcaaatacatctgaaggagct
acgtctggattaataattcctcttactatatctggaggctcaggccccaggccattaaat
cctgtacctcaagctcccctaccacctggttgggagcagagaatggaccaacatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgagttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacatggcagaggccaacattggaatctgtccggaactatgaacagtggcag
ctccagcgtagtcaacttcaaggagcaatgcagcagtttaatcagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccttgggtcccctgcca
cctggatgggagaagagaacggacagcaatggaagagtatattttgtcaaccacaacact
cgtattacacagtgggaggaccccaggagtcaaggtcagttaaatgaaaagcccttacct
gaaggttgggaaatgagattcacagtggatggaattccatattttgtggaccacaataga
agaacaaccacctatatagatccccgcactggaaaatctgccctagacaatggaccccag
atagcctatgtacgagacttcaaggcaaagtttcagtatttccggttctggtgtcagcaa
ctggccatgccacaacacataaagattacagtgacaaggaaaacattgtttgaggattct
tttcagcagataatgagcttcagtccccaagatctccgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgatttatt
ggaaggtttattgccatggctctgttccatgggaaattcatagacacaggcttttctttg
ccattctataagcgtatcttgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaacattgaggaatgtggattg
gaaatgtacttctctgttgataaagaaattttgggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatattcttgtaacagaagaaaataaagaagaatatatcagaatggta
gccgaatggaggttgtctcgaggtgttgaagaacagacgcaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcagtactttgatgcaaaggaattagaggtcctt
ttatgtggaatgcaagagattgatctaaatgattggcaaagacatgccatttaccgtcat
tacactaggacaagtaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgtattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaaactgttatttgccattgaagaaacagaaggatttgga
caagagtga
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