Pteropus vampyrus (large flying fox): 105304450 Help Entry 105304450         CDS       T07815                                  Name (RefSeq) ryanodine receptor 2   KO K04961   ryanodine receptor 1 Organism pvp  Pteropus vampyrus (large flying fox) Pathway pvp04020   Calcium signaling pathway pvp04371   Apelin signaling pathway pvp04713   Circadian entrainment pvp04730   Long-term depression pvp04921   Oxytocin signaling pathway pvp05017   Spinocerebellar ataxia pvp05020   Prion disease pvp05022   Pathways of neurodegeneration - multiple diseases Brite KEGG Orthology (KO) [BR:pvp00001]  09130 Environmental Information Processing   09132 Signal transduction    04371 Apelin signaling pathway     105304450    04020 Calcium signaling pathway     105304450  09150 Organismal Systems   09152 Endocrine system    04921 Oxytocin signaling pathway     105304450   09156 Nervous system    04730 Long-term depression     105304450   09159 Environmental adaptation    04713 Circadian entrainment     105304450  09160 Human Diseases   09164 Neurodegenerative disease    05017 Spinocerebellar ataxia     105304450    05020 Prion disease     105304450    05022 Pathways of neurodegeneration - multiple diseases     105304450  09180 Brite Hierarchies   09181 Protein families: metabolism    01009 Protein phosphatases and associated proteins [BR:pvp01009]     105304450   09183 Protein families: signaling and cellular processes    04147 Exosome [BR:pvp04147]     105304450    04040 Ion channels [BR:pvp04040]     105304450 Protein phosphatases and associated proteins [BR:pvp01009]  Protein serine/threonine phosphatases   Phosphoprotein phosphatases (PPPs)    Protein phosphatase-1     PP1-interacting proteins (PIPs)      105304450 Exosome [BR:pvp04147]  Exosomal proteins   Exosomal proteins of other body fluids (saliva and urine)    105304450 Ion channels [BR:pvp04040]  Voltage-gated cation channels   Ryanodine receptor    105304450 BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  RR_TM4-6 RYDR_Jsol RYDR_ITPR RyR RIH_assoc Ion_trans EF-hand_7 EF-hand_1 SPRY EF-hand_8 EF-hand_6 EF-hand_5 Motif Other DBs NCBI-GeneID:  105304450 NCBI-ProteinID:  XP_023378135 UniProt:  A0A6P6BT56 LinkDB All DBs Position Unknown AA seq 3116 aa AA seqDB search FLLRRTKPDYSTSHSARLTEDVLAGDRDDHDCLMQTSTYYYSVRIFPGQEPASVWVGWIT SDFHQYDTGFDLDRVRTVTVTLGDEKGKVHERKVGRNGACQLMTVSSVLSCQLMTVSSVL SCWLMTVSCVLSCQLMTVSSVLSSLVYCWNVMPLSAGLFKSEHRNPVPQCPPRLHVQFLS HVLWSRMPNQFLKVDVSRVSERQGWLVQCVDPLQFMSLHIPEENRSAPRRRGGTHNEAKT RVTARGDGDAIAYVPSMCLLLQYLCDCQVRHRIEAIVAFSDNFVAKLQDNQRFRYNEVMQ ALNMSAALTARKTREFRSPPQEQINMLLNFKDDKSECPCPEEIRDQLLDFHEDLMAHCGI ELGEDGSLDGNSDLTIKGRLLSLVEKVTYLKKKQTEKPVERDARKSSTLQQLISDTMVRW AQESVIEDPELVRAMFVLLHRQYDGIGGLIRALPKTYTINSVSVEDTINLLASLGQIRSL LSVRMGKEEEKLMIRGLGDIMNNKVFYQHPNLMRALGMHETVMEVMVNVLGGGESKEITF PKMVANCCRFLCYFCRISRQNQKAMFDHLSYLLENSSVGLASPAMRGSTPLDVAAASVMD NNELALALREPDLEKVVRYLAGCGLQSCQMLVCKGYPDIGWNPVEGERYLDFLRFAVFCN GESVEENANVVVRLLIRRPECFGPALRGEGGAGLLAAIEEANRIAEDPSRDGPSPTSESA KTPDAEEEEDDTIHMGNAIMTFYAALIDLLGRCAPEMHLIHAGKGEAIRIRSILRSLIPL GDLVGVISIAFQMPTVAKDGNVVEPDMSAGFCPDHKAAMVLFLDRVYGIEVQDFLLHLLE VGFLPDLRAAASLDTAALSATDMALALNRYLCTAVLPLLTRCAPLFAGTEHHASLIDSLL HTVYRLSKGCSLTKAQRDSIEVCLLSICGQLRPSMMQHLLRRLVFDVPLLNEHAKMPLKL LTNHYERCWKYYCLPGGWGNFGAASEEELHLSRKLFWGIFDALSQKKYEQELFKLALPCL SAVAGALPPDYMESNYVSMMEKQSSMDSEGNFNPQPVDTSKCSQHAVRRCSCEPQASPQH ASSSQAQGCRWCAACRAQRAGDREKEIYRWPIKESLKTMLAWGWRIERTREGDSMALYSR TRRISQTSQVSVDAAHGYSPRAIDMSNVTLSRDLHAMAEMMAENYHNIWAKKKKVELESK GGGNHPLLVPYDTLTAKEKAKDREKAQDILKFLQISGYVVSRGFKDLELDTPSIEKRFAY SFLQQLIRYVDGAHQYILEFDGGSRGKGEHFPYEQEIKFFAKFVFSLFCKLGVLVRHRIS LFGNDATSIVNCLHILGQTLDARFSFFIVEDVQVSCYRILTSLYALGTSKSIYVERQRSA LGECLAAVAGAFPVAFLETHLDKHNIYSIYNTKSSRERAALNLPASVEDVCPNIPSLEKL MGEIVEVAESGVRYTQMPHVMEVVLPLLCSYLSRWWEHGPESNPARAATCCTALSSEHMN TLLGNILKIIYNNLGIDEGAWMKRLAVFSQPIINKVKPQLLKTHFLPLMEKLKKKAAMVV SEEEHLKAEARGDMSEAELLILDEFTTLARDLYAFYPLLIRFVDYNRAKWLKEPNPEAED LFRMVAEVFIYWSKSHNFKREEQNFVVQNEINNMSFLITDTKSKMSKAAGSDQERKKMKR KGDRYSMQTSLIVAALKRLLPIGLNICAPGDQELIALARNRLSMKDTEEEVRDIIRSNIH LQGKLEDPAIRWQMALYKDLPNRTEDSSDPEKTVERVLDIANVLFHLEQVEHPQRSKKAV WHKLLSKQRKRAVVACFRMAPLYNLPRHRAVNLFLQGYEKSWIETEEHYFEDKLIEDLAK PGAEPAEEEEGAKTVDPLHQLILLFSRTALTEKCKLEEDFLYMAYADIMAKSCHDEEDDD SEEEVKSFEEKEMEKQKLLYQQARLHDRGAAEMVLQTVSASKGETGPMVAATLKLGIAIL NGGNATVQQKMLDYLKEKKDVGFFQSLAGLMQSCSVLDLNAFERQNKAEGLGMVTEEGSG EKVLQDDEFTCDLFRFLQLLCEGHNSDFQNYLRTQTGNNTTVNIIISTVDYLLRVQESVS DFYWFYSGKDVIDEQGQRNFSKAIQVAKQVFNTLTEYIQGPCTGNQQSLAHSRLWDAVVG FLHVFAHMQMKLSQDSSQIELLKELMDLQKDMVVMLLSMLEGNVVNGTIGKQMVDMLVES SNNVEMILKFFDMFLKLKDLTSSDTFKEYDPDGKGVISKREFHKVMESHKHYTQSETEFL LSCAETDENETLDYEEFVKRFHEPAKDIGFNVAVLLTNLSEHMPNDTRLQTFLELAESVL NYFQPFLGRIEIMGSAKRIERVYFEISKSSRTQWEKPQVKESKRQFIFDVVNEGGEKEKM ELFVNFCEDTIFEMQLAAQISESDLNERSASKEESEAEKPEEQGPRMAFFSMLTVATALL ALRHNALTLLRMLSLKSLRKQMKKVKKMTVRDMAAALFSSYWGVSRSLLHFAASVLRGFS RIVCGLLLGGSLVEGAKKIRVAELLANMPDPTQDEVRGDGEEAERKPLEAALPSEDLTDL KELAEESDLLSDIFGLDLKREGGQYKLIPHNPNAGLSDLMSNPVPTPEVQDKCQEQKAKE EEKEEKEEKSEPDKAGGENGEKEEKAKEEKGKQKLRPLHTHRYGEPEAPESAFWKKIIAY QQKLLNYFARNFYNMRMLALFVAFAINFILLFYKVSTSSAVEGRELPARGSGEGEGAAVG GLGGGALRGAAVHYVLEESSGYMEPALRILAVLHTAISFCCIIGYYCLKVPLVIFKREKE VARKLEFDGLYITEQPSEDDIKGQWDRLVINTQSFPNNYWDKFVKRKSFLYLAWYMTMSV LGHFNNFFFAAHLLDIAMGFKTLRTILSSVTHNGKQLVLTVGLLAVVVYLYTVVAFNFFR KFYNKSEDGDTPDMKCDDMLTVSSHALVGVRAGGGIGDEIEDPAGDEYEIYRIIFDITFF FFVIIILLAIIQGLIIDAFGELRDQQEQVKEDMETKCFICGIGNDYFDTVPHGFETHTLQ EHNLANYLFFLMYLINKDETEHTGQESYVWKMYQERCWEFFPAGDCFRKQYEDQLN NT seq 9352 nt NT seq  +upstreamnt  +downstreamnt gtttttgctgaggagaacgaagccagattacagcacaagccactccgcgaggctcacgga ggacgtcctcgcgggggaccgggacgaccacgactgcctgatgcagacgtccacgtacta ttactcagtgagaatctttcctggacaagagccggccagcgtctgggtgggctggatcac gtccgacttccaccagtatgacacgggcttcgacttggacagagttcgcacagtaaccgt tactctgggcgacgaaaaaggaaaagtgcacgaaaggaaggtggggaggaacggagcgtg tcagctgatgacggtcagctccgtgctgtcatgtcagctgatgacggtcagctccgtgct gtcgtgttggctgatgacggtcagctgcgtgctgtcgtgtcagctgatgacggtcagctc cgtgctgtcgtctctggtgtactgctggaacgtgatgccgctgtccgcggggctgttcaa gagcgagcacaggaaccccgtgccgcagtgcccgccgcgcctgcacgtgcagttcctgtc gcacgtgctgtggagcaggatgcccaaccagttcctgaaggtggacgtgtcgcgggtcag cgagcgccagggctggctggtgcagtgcgtggaccccctgcagttcatgtccctgcacat cccggaggagaacaggtctgccccgcgccgtcggggggggacacacaacgaggctaaaac acgtgtcacggctcgtggcgacggagacgccatcgcgtacgttccaagtatgtgcctgct gctccagtacctctgtgactgccaggtccggcaccggatagaagccatcgtggccttttc ggataacttcgtagctaagctccaagacaaccagcgcttccgatacaatgaagttatgca agccttgaacatgtcggctgcactcacagccaggaaaacgagggaatttaggtcaccacc tcaagaacagatcaatatgcttctcaattttaaggatgacaaaagcgaatgtccgtgtcc tgaagaaatccgggaccaactcttggattttcacgaagacctgatggcacattgtggaat tgagctgggcgaggacgggtctctggatggaaacagcgatttgacaattaaaggacgcct gctgtccctggtagaaaaggtgacatacctgaagaagaaacaaactgaaaagccagttga gcgtgacgccaggaagtcctccacccttcagcagctgatctctgacaccatggttcgatg ggctcaagagtctgtcattgaagaccctgagctggtgagggccatgttcgtgttgctcca tcgacagtatgatggcattgggggcctgatccgggccctgccaaaaacctacactataaa cagtgtttctgtggaggacaccatcaacctgctggcatctctcggtcagatccgttctct gctgagcgtgaggatgggcaaagaagaagagaagcttatgatccgtggattaggggatat catgaataacaaagtgttttaccagcaccctaatctcatgagggcactgggcatgcacga gacagtgatggaggtcatggtgaatgtcctcggaggtggggagtccaaggagatcacttt tcccaagatggtggccaactgttgccgttttctctgttacttctgtcggataagccggca gaatcagaaagccatgtttgaccatctcagttatttattggaaaacagtagtgttggtct cgcctcgccagctatgagaggttcaacaccgctggatgtggcagcagcctcggtgatgga taacaatgaactggccttagctttgcgtgagcccgacctggaaaaggtcgtccggtatct ggctggctgtggactgcagagttgccagatgctggtgtgtaaggggtacccagatattgg ctggaacccagttgaaggggagcggtacctcgacttcctcagatttgctgtcttctgtaa tggggagagtgtggaggaaaatgccaacgtcgtggtgaggctgctcatccggaggcctga gtgcttcggcccggctctgagaggggagggcggggccggccttctcgccgccatagagga agccaaccggatagccgaggacccttcccgagacggaccctcgccaaccagcgaatccgc gaaaacccctgacgcggaggaggaggaggacgacactatccacatggggaacgccatcat gaccttctacgcagctctcatcgacctgctgggacgctgcgctcccgagatgcacctgat tcatgctggtaagggagaagccatcaggatcagatctattttgagatccctgattccact gggagatttggtgggcgtaatcagcatcgctttccagatgcccacggtagccaaggatgg gaatgtggtggagcctgacatgtccgcggggttttgcccagatcacaaggcagccatggt tttgttccttgacagggtctatgggattgaggttcaggatttcctcctgcatcttctaga ggttggctttctgccagatctccgggctgctgcttctttagatacggccgcgttgagtgc cacggacatggccttggccctgaatcggtacttgtgcacggccgtgctgcctctgttgac gagatgtgcccctctttttgctggcacagagcaccacgcttccctcatcgactcgttact tcataccgtgtacaggctttctaagggctgttcgctgaccaaagctcagcgggattccat agaagtttgtttgctgtctatttgtggccagttgagaccttctatgatgcagcacttact cagaagattagtgtttgatgtcccgttactaaacgagcacgcgaagatgccacttaagct gctgacaaatcattatgaaagatgctggaaatattactgcctgcctggagggtggggaaa ctttggagctgcctcagaagaagaacttcatttatcaagaaagttgttctggggcatttt tgatgccctgtctcaaaagaaatatgaacaagaacttttcaaactggcactgccgtgcct gagcgcagttgcgggagctttgcctccagactacatggagtcaaattatgtcagtatgat ggaaaaacagtcatcaatggattctgaagggaactttaacccacagcccgttgatacctc aaaatgctcccagcatgcagtgcggcgctgttcctgcgagccgcaggcgtcccctcagca cgcctcgtccagccaggcccaggggtgccgctggtgtgcagcttgcagagcacagcgtgc gggtgacagggaaaaagaaatctatcgctggccaatcaaagaatctctgaaaacgatgct ggcttggggctggagaatcgagcggacgcgggagggagacagcatggcgctctacagcag gacacggcgcatctcgcagacgagccaggtctctgtggatgctgcccacggttacagtcc ccgggccatcgacatgagcaacgtcacactgtctagagatctgcatgcgatggcagaaat gatggccgaaaactaccataacatatgggcaaagaaaaagaaagtggagctggagtccaa aggaggcggaaaccatcccctgctcgtgccctacgacacgctgacagccaaagagaaagc caaggacagggaaaaagcccaggacatcctcaagttcctgcagatcagtggatatgttgt gtccagagggttcaaggacctggaactggacacgccttccattgaaaagcgatttgccta cagcttcctgcagcagctcatacgctatgtggacggagcccatcagtacatcctggagtt cgatgggggcagcagaggcaaaggagagcatttcccctacgagcaagaaatcaagttctt cgctaagtttgtcttcagcctattctgcaaactcggagttcttgtcaggcataggatttc actatttggaaatgatgcgacatcgattgtcaactgtctccatattttgggtcagacttt ggatgcgagattttctttcttcatagtggaagatgtacaggtgtcatgttatagaattct gaccagcttatatgctttgggaacgagcaagagcatttatgtggaaaggcagcgttctgc attaggagagtgtctggctgccgttgctggtgcctttcccgtggcgtttctggaaactca tctcgacaaacataatatttactctatctacaacactaagtcctcacgagagagagcagc tctcaacctgccggccagcgtggaagatgtctgcccgaacatcccgtccttggagaagct catgggcgagatcgtggaggtggccgagtccggcgtccgctacacgcagatgccacacgt gatggaagtcgtcctgcccctgctgtgcagctacctgtcgcgctggtgggagcacggccc cgagagcaacccggcccgagccgcgacgtgctgcacggcgctcagctccgagcacatgaa caccctgctgggcaacatcctgaagatcatatacaacaacctgggcatcgacgagggcgc ctggatgaagaggctggcagtattttcccagcctattataaacaaagtgaaacctcagct cttgaaaactcacttcttgccactgatggagaaactcaagaaaaaggcagcgatggtggt gtccgaggaggagcatctgaaagccgaggccaggggggacatgtccgaggccgagctgct catcctggacgagttcaccacgctggcccgagacctctacgccttctaccctctcttgat tagattcgtggactataacagggccaagtggctcaaagagccgaacccagaagccgagga ccttttccgcatggtggccgaagtcttcatctactggtcgaaatcccacaatttcaaaag agaagagcagaactttgttgtccagaacgaaatcaacaacatgtctttcctcattacaga caccaagtcgaagatgtccaaggcggccgggtctgaccaggagcggaagaagatgaagcg caagggagaccgctactccatgcagacgtccctcatcgtggccgcgctgaagcggctgct gcccatcggcctgaacatctgcgccccgggcgaccaggagctcatcgccctggccaggaa ccggctcagcatgaaagacacggaggaagaagtacgcgacatcatccgcagtaatattca cttacagggcaagttggaggaccctgccatcagatggcagatggctctttacaaagactt gccgaacaggactgaggacagttcggatcccgagaagacagtagaaagagtgctggacat agcaaatgtgcttttccatcttgaacaggtggagcatccgcagaggtccaagaaggccgt ctggcacaagctgctctccaagcagaggaaaagggccgtggtggcctgcttccgcatggc accgttgtataacctgccaaggcatcgggccgttaatctctttcttcagggatatgaaaa gtcctggattgaaacagaagaacattactttgaagataaactgatagaagatttagcaaa acctggagcggagcctgcagaggaagaggaaggcgccaagacagtcgaccctctgcacca gctgatccttctgttcagtcggacggctctgacggagaaatgcaaactggaggaagattt tttatacatggcgtatgcagatattatggcaaagagttgtcatgacgaggaagatgatga tagtgaagaagaagtgaagagtttcgaggaaaaagaaatggaaaagcaaaagcttctgta ccagcaagcccgtctgcacgaccgcggggccgctgagatggtgctgcagaccgtcagcgc cagcaaaggtgagaccggcccgatggtcgccgccacgctgaagctcggaatcgccatcct caacggcgggaacgccacggtgcagcagaaaatgctcgactacctcaaggagaagaaaga cgtgggcttcttccagagcctggccggcctcatgcagtcctgcagtgtcctcgacctgaa tgcctttgagcgacagaacaaagctgaaggactcggaatggtgacagaggaaggatcagg agaaaaggtcctgcaggatgatgagttcacctgtgacctcttccgcttcctgcagctgct ttgtgagggacacaactcagattttcagaattacctgagaacgcagaccggcaacaacac aactgtcaacatcatcatctccaccgtcgattacctgctgagagtccaggagtcggtcag cgatttctactggttttactccggaaaagatgtcatcgacgagcaaggacagaggaattt ctccaaagcgattcaagtcgcaaagcaagtcttcaacacgctcacggagtacattcaggg cccgtgcactggcaaccagcagagtctggcccacagccggctctgggacgcggtggtcgg cttcctgcacgtgtttgcccacatgcagatgaagctgtctcaggattccagtcaaatcga gctgctgaaggagctgatggacctgcagaaggacatggtggtgatgctgctgtccatgct ggaaggtaacgtcgtgaacgggaccatcggcaagcagatggtcgacatgcttgtggagtc ttccaacaacgtggagatgattctcaagttcttcgacatgttcttaaaactgaaagactt gacatcctctgacacatttaaggaatatgaccccgatggcaagggcgtcatttccaagag ggagttccacaaagtgatggaaagccacaagcactacacgcagtcagagaccgagttcct cctgtcctgcgcggagacggacgagaacgagaccctcgactacgaggaattcgtcaaacg tttccacgagcccgcgaaggacatcggcttcaacgtcgccgtgctcctgacgaacctttc cgagcacatgcccaacgacacgcgcctgcagaccttcctggagctggccgagagcgtgct caactacttccagcccttcctgggccgcatcgagatcatgggcagcgccaagcgcatcga gagggtttacttcgaaatcagcaagtccagccggacgcagtgggagaagccgcaggtcaa ggagtccaagaggcagttcatcttcgatgtggtcaacgagggcggcgagaaggagaagat ggagctcttcgtgaacttctgcgaggacaccatcttcgagatgcagctggcggcccagat ctcggagtcggacttgaacgagcgctcggccagcaaagaggagagcgaggcggagaagcc cgaggagcaggggccgcgcatggccttcttctccatgctgaccgtcgcgaccgccttgct cgccctcaggcacaacgccctgacccttctgcgcatgctcagcctgaagagcctgcggaa gcagatgaagaaggtgaagaagatgacggtgagggacatggctgctgccctcttctcctc ctactggggcgtgtcgcggagcctcctgcacttcgcggccagcgtgctcagaggcttctc ccgcatcgtctgcggcctgctgctgggaggcagcctcgtggaaggcgccaagaagatccg agtggccgagctcctggccaacatgccggaccccacgcaggacgaggtgaggggagacgg cgaggaggccgagaggaagccgctggaggccgccctgccctcggaggacctcacggacct gaaggagctggcggaggaaagcgacctcctctcagacatatttggcttggatctgaagag agaaggaggacagtataagctcatccctcataacccgaacgccggcctcagcgacctcat gagcaaccccgtccccacccccgaggtgcaagacaagtgtcaggaacagaaggcaaaaga ggaggaaaaggaagaaaaagaagagaaatcggagcctgacaaagccgggggagaaaatgg ggaaaaagaagaaaaagccaaggaagagaaaggcaaacagaagctccggccgctgcacac acacagatacggggagccagaggcccccgagtcagcattctggaagaaaatcatagctta tcaacagaagctgctaaactattttgctcgcaacttttacaacatgagaatgttagcctt gtttgtcgcgtttgcgatcaatttcatcttgctcttctacaaggtctccacttcttctgc ggtggaaggaagggagctccccgcgcgcggctccggggaaggcgaaggcgccgcggtggg cggcctgggcggcggggccctgcgcggcgcggccgtgcactacgtcctggaggagagcag cggctacatggagcccgcgctgcgcatcctggccgtgctgcacaccgccatctccttctg ctgcatcatcggctactactgcctgaaggtcccactggttatttttaagcgagagaagga agtagctcgaaaattggaatttgatggactttatattacagaacagccttcagaagatga tattaaaggccagtgggatagacttgtaatcaacacacagtcatttcccaataactactg ggacaaatttgttaaaagaaagtccttcctctaccttgcctggtacatgaccatgtctgt tctcggacactttaacaactttttttttgctgctcatcttcttgacatcgctatggggtt caagacgctgagaaccatcttgtcatcagtaactcacaatggcaaacagctggtattaac cgtgggcttgttagctgtggtcgtgtacctgtatactgttgtggcattcaattttttccg aaaattctacaataaaagtgaagatggagatacgccagacatgaaatgtgacgatatgct aacggtaagttcacacgctttggtnggggttcgtgccggagggggcatcggggacgaaat cgaggaccctgcgggcgacgagtacgagatctaccgcatcatcttcgacatcaccttctt cttcttcgtgatcatcatcctcttggccataatacaaggtttaattatcgatgctttcgg agagctcagagaccagcaggagcaagtcaaagaggacatggagaccaaatgcttcatctg cggcataggcaacgattacttcgatacggtgccgcacggcttcgaaacccacaccttaca ggagcacaacctggccaattacctgtttttcctgatgtatctcataaacaaggatgaaac cgagcacacaggacaggagtcttatgtctggaagatgtatcaagaaagatgctgggagtt tttcccagcgggggactgtttccggaaacagtatgaagaccagctcaattaa

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