KEGG   Pteropus vampyrus (large flying fox): 105307393
Entry
105307393         CDS       T07815                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X2
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
pvp  Pteropus vampyrus (large flying fox)
Pathway
pvp01522  Endocrine resistance
pvp04110  Cell cycle
pvp04115  p53 signaling pathway
pvp04151  PI3K-Akt signaling pathway
pvp04218  Cellular senescence
pvp04530  Tight junction
pvp04660  T cell receptor signaling pathway
pvp04933  AGE-RAGE signaling pathway in diabetic complications
pvp04934  Cushing syndrome
pvp05160  Hepatitis C
pvp05162  Measles
pvp05163  Human cytomegalovirus infection
pvp05164  Influenza A
pvp05165  Human papillomavirus infection
pvp05166  Human T-cell leukemia virus 1 infection
pvp05167  Kaposi sarcoma-associated herpesvirus infection
pvp05169  Epstein-Barr virus infection
pvp05200  Pathways in cancer
pvp05203  Viral carcinogenesis
pvp05212  Pancreatic cancer
pvp05214  Glioma
pvp05218  Melanoma
pvp05219  Bladder cancer
pvp05220  Chronic myeloid leukemia
pvp05222  Small cell lung cancer
pvp05223  Non-small cell lung cancer
pvp05224  Breast cancer
pvp05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:pvp00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    105307393 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    105307393 (CDK4)
   04115 p53 signaling pathway
    105307393 (CDK4)
   04218 Cellular senescence
    105307393 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    105307393 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    105307393 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    105307393 (CDK4)
   05203 Viral carcinogenesis
    105307393 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    105307393 (CDK4)
   05225 Hepatocellular carcinoma
    105307393 (CDK4)
   05214 Glioma
    105307393 (CDK4)
   05220 Chronic myeloid leukemia
    105307393 (CDK4)
   05218 Melanoma
    105307393 (CDK4)
   05219 Bladder cancer
    105307393 (CDK4)
   05224 Breast cancer
    105307393 (CDK4)
   05222 Small cell lung cancer
    105307393 (CDK4)
   05223 Non-small cell lung cancer
    105307393 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    105307393 (CDK4)
   05160 Hepatitis C
    105307393 (CDK4)
   05164 Influenza A
    105307393 (CDK4)
   05162 Measles
    105307393 (CDK4)
   05163 Human cytomegalovirus infection
    105307393 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    105307393 (CDK4)
   05169 Epstein-Barr virus infection
    105307393 (CDK4)
   05165 Human papillomavirus infection
    105307393 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    105307393 (CDK4)
   04934 Cushing syndrome
    105307393 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    105307393 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pvp01001]
    105307393 (CDK4)
Enzymes [BR:pvp01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     105307393 (CDK4)
Protein kinases [BR:pvp01001]
 Serine/threonine kinases: CMGC group
  CDK family
   105307393 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 105307393
NCBI-ProteinID: XP_011381196
UniProt: A0A6P3RQE0
LinkDB
Position
Unknown
AA seq 302 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGAGGGLPISTVREVALLR
RLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDLM
RQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWYR
APEVLLQSTYATPVDLWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPRD
VSLPRGAFSPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSYLQKAEGN
PE
NT seq 909 nt   +upstreamnt  +downstreamnt
atggctacccctcgatatgagccagtggctgagattggtgttggtgcctatggaacggtg
tacaaggcccgtgatccccacagtggccactttgtcgccctcaagagcgtgagagttccc
aatggaggtgctggagggggccttcccatcagcacagttcgtgaggttgctttactgagg
cggctggaggcttttgagcatcccaatgttgtccggctgatggatgtctgtgccacagcc
cgaactgaccgggaaaccaaagtgaccctggtgtttgagcatgtggaccaagacctaagg
acgtatctggataaggcacccccaccaggcttgccagtggagaccatcaaggatctgatg
cgccagtttctaagaggcctagatttccttcatgccaactgcattgttcaccgggaccta
aagccagagaacattctggtgacaagtggtgggacagtcaagctggctgactttggcctg
gccagaatctacagctaccagatggcacttacacctgtggttgttacactctggtaccgt
gctccagaagttcttctgcagtctacgtatgcaacacctgtggacttgtggagtgttggc
tgtatcttcgctgagatgtttcgtcgaaagcctctcttctgcggaaattctgaagctgac
cagttaggcaaaatctttgacttgattgggctgcccccagaggatgactggccccgagat
gtctctctaccccggggagccttttcccccagagggccccgtccagtgcagtcggtggta
cctgagatggaggagtctggagcacagctgctgctggagatgctgacttttaacccacac
aagcgaatctctgccttccgagccctgcagcattcttatctacaaaaggcagaaggtaac
ccagagtga

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