Pleurodeles waltl (Iberian ribbed newt): 138248956
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Entry
138248956 CDS
T10800
Symbol
HSD3B1
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00140
Steroid hormone biosynthesis
pwl01100
Metabolic pathways
Module
pwl_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
pwl_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
pwl_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
pwl_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
138248956 (HSD3B1)
Enzymes [BR:
pwl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
138248956 (HSD3B1)
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
138248956 (HSD3B1)
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GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
Polysacc_synt_2
GDP_Man_Dehyd
RmlD_sub_bind
NAD_binding_10
KR
NmrA
Motif
Other DBs
NCBI-GeneID:
138248956
NCBI-ProteinID:
XP_069059092
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Position
8:complement(1539183892..1539221138)
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AA seq
380 aa
AA seq
DB search
MPASLAGVRCLVTGAGGFLGQKIVQMLLEEEEGLAELRMMDLAFSPTLLRVCDNYQGKTK
LQLMKGDIQDAMLLLRASQGLSLVIHTAAIIDTLGKFPAEKVMGVNVKGTQLLLDACIQN
NVNNFIYTSSVEVVGPNMRGDPIFNGTEDLVYESNDSFIYGRSKRIAEKCVLQANGQPLD
NGTSLVTCALRCMYIFGEESQFLMMHLDGAIMNRDVFPRLSRKEAAVNPAFVGNVAWAHI
QAAKAMRDPELVSQVGGQFYYISDDTPHLSYSDFNHELGKELGFGVEPKLCMPLSLLYTF
AFVMEMVSLLLRPFVKFVPPTSRHLLNLLHTPFTFSYKKAQKDFGYKPRYSWEDAKRITT
AWMAAQVPLRREILKRQKQR
NT seq
1143 nt
NT seq
+upstream
nt +downstream
nt
atgccagcgtccctcgccggggtgaggtgcctggtgaccggggccgggggcttcctgggg
cagaagatagtgcagatgctgctggaggaagaggagggcctggccgagctccgcatgatg
gacctggccttcagcccgaccctgctgagggtctgtgacaattaccagggaaagacgaag
ctgcagctgatgaagggggacatccaggacgccatgctgctgcttagggccagccagggc
ctgtcgctggtcatccacacggcagccatcattgacacgctggggaagttccctgcggag
aaggtcatgggagtcaacgtgaaaggtacccagctgctgttggacgcctgcatccagaac
aacgtgaacaacttcatctacactagcagtgtggaggttgtcggtccgaatatgagaggg
gaccctatcttcaacggcaccgaagacctggtgtatgagagcaacgacagcttcatctac
ggccggagcaaacgcatcgctgagaagtgtgtcctgcaggccaacggacagccactggac
aacggcaccagcctggtgacctgcgctttgcgttgcatgtatatctttggagaagaaagt
cagttcttgatgatgcacctggacggcgccatcatgaacagagatgtcttcccgaggttg
tcccggaaggaggctgcggtgaacccagcctttgtgggcaacgtggcatgggcacacatt
caggccgccaaagctatgcgggacccagagctcgtgtctcaggtcggtgggcagttttac
tacatctcagatgacaccccacacctgagctactcagacttcaaccatgagctgggaaag
gagcttggctttggggtggagcccaagctctgcatgcctctctcgctgctttacaccttt
gcctttgtgatggagatggtgagcctcttgctgaggcctttcgtgaaatttgtgcccccg
accagtcgccacctgctcaacttgttgcataccccattcaccttctcctacaagaaagcc
caaaaggactttggttacaaaccccgctacagctgggaggatgccaagcggataacgact
gcctggatggctgcccaggtcccactgcgcagggagattctgaagcgacaaaagcaacgt
taa
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