Pleurodeles waltl (Iberian ribbed newt): 138286531
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Entry
138286531 CDS
T10800
Symbol
HSD17B4
Name
(RefSeq) peroxisomal multifunctional enzyme type 2
KO
K12405
(3R)-3-hydroxyacyl-CoA dehydrogenase / 3a,7a,12a-trihydroxy-5b-cholest-24-enoyl-CoA hydratase / enoyl-CoA hydratase 2 [EC:1.1.1.-
4.2.1.107
4.2.1.119
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00120
Primary bile acid biosynthesis
pwl01040
Biosynthesis of unsaturated fatty acids
pwl01100
Metabolic pathways
pwl01212
Fatty acid metabolism
pwl04146
Peroxisome
Module
pwl_M00861
beta-Oxidation, peroxisome, VLCFA
pwl_M00862
beta-Oxidation, peroxisome, tri/dihydroxycholestanoyl-CoA => choloyl/chenodeoxycholoyl-CoA
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09100 Metabolism
09103 Lipid metabolism
00120 Primary bile acid biosynthesis
138286531 (HSD17B4)
01040 Biosynthesis of unsaturated fatty acids
138286531 (HSD17B4)
09140 Cellular Processes
09141 Transport and catabolism
04146 Peroxisome
138286531 (HSD17B4)
Enzymes [BR:
pwl01000
]
4. Lyases
4.2 Carbon-oxygen lyases
4.2.1 Hydro-lyases
4.2.1.107 3alpha,7alpha,12alpha-trihydroxy-5beta-cholest-24-enoyl-CoA hydratase
138286531 (HSD17B4)
4.2.1.119 enoyl-CoA hydratase 2
138286531 (HSD17B4)
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Gene cluster
GFIT
Motif
Pfam:
MFE-2_hydrat-2_N
adh_short
MaoC_dehydratas
adh_short_C2
SCP2
KR
Alkyl_sulf_C
FAS1_DH_region
Epimerase
ApeI-like
Motif
Other DBs
NCBI-GeneID:
138286531
NCBI-ProteinID:
XP_069082996
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Position
1_1:660846418..661486893
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AA seq
737 aa
AA seq
DB search
MASPLRFDGKVVLVTGAGGGLGRAYALAFAERGASVVVNDLGSTTSGGGSSFSAADRVVE
EIKAKGGKAVANYDSVEDGEKVVQTALDAFGRIDVVINNAGILRDRSFPRISDADWDIIQ
RVHLRGSFLVTRAAWNHMKNQNYGRIIMTSSAAGIYGNFGQANYSAAKLGLLGLSNTLAI
EGQKYNIFSNTIAPLAGSRLTETVMPPDLVSALKPEYVAPLVLWLCHESCQETGGLYEVG
AGWIGKLRWERSLGTVVRQKNTPITPEAVRDNWDKISDFDHVSYPQSTKDSMQPIYELVF
KLDSEEGVTMNPTSQHVSAGVSAIDPTKAIGYQLPTSTYSYTHFQPILYALGVGMSTKDA
DHLRFLYEGSEDFCCLPTFGVIPSQASMSGLANVPGLSIDFTRLLHGEQYLEVYKPLPTS
GQLTFTATIADVLDKGSGAVILLDVHTYCGKDLICYNQFSIFIVGAGGFGGKRTSDKAKP
TANPPSRAPDAVLSDVTSADQAALYRLSGDWNPLHIDPNFAVLGGFQKPILHGLCSFGFA
GRHVLKQFADNDVTKFKAIKVRFAKPVLPGQTLQTEMWKEGNRIYLQTKVKETGQIAIAG
AYVDLTLAAQLSPSNELAEATELRSDLVFEEIIRRIKDLGEEMVAKVNAIFQWDITKDGK
TVAQWTINLKNGSGEAYKGPARGQVDTTFTVSDTDFMEIVIGKLNPQKAFFSGKLKVKGN
IMLSQKLELILKDHAKL
NT seq
2214 nt
NT seq
+upstream
nt +downstream
nt
atggcatccccgctgagatttgatgggaaagtggtgcttgtgacaggagctggaggaggt
ttggggcgagcgtacgccttggcgtttgcagagaggggagcctctgtagtggtgaatgac
ctcggaagcactaccagtggaggcggcagcagtttctccgcggctgaccgtgtcgtcgaa
gaaataaaggccaaaggggggaaagcagttgccaactatgattctgtggaagatggtgag
aaggtcgtccagactgctcttgatgcctttggaagaatagatgttgttataaacaatgct
gggattttgagagatcgttcgtttccaaggataagtgatgctgattgggacatcattcaa
agagtgcatttaagggggtcattcttggtgaccagagcagcatggaatcacatgaagaac
cagaattatggaagaataataatgacttcgtctgctgctggaatttatggcaactttgga
caagcaaattacagtgctgccaaactgggacttctgggtttgtcaaatacgttggcaatt
gagggccaaaaatacaacatatttagtaataccattgcgcctcttgcaggatccagattg
actgagaccgtcatgcctccagatttggtgagcgcactgaaacctgaatatgtagcacct
cttgtcctgtggctttgtcatgaaagctgccaagagactggtggtctttatgaggttggt
gctggttggattggaaagttgcggtgggaacgatcgcttggcactgttgtccgacagaag
aatactccgatcacaccagaagctgtacgagacaactgggacaagatcagtgactttgat
catgtctcttatccccagtcaacaaaagattctatgcagcccatttatgagttggtgttc
aaactagattctgaggagggtgtaacaatgaatcctacaagtcaacatgtttcagcaggg
gtctctgctattgacccaactaaagcaattggttaccagttacccacatcaacgtattca
tacacccattttcagcccattttgtatgcacttggggtgggaatgtctaccaaagatgca
gaccacctgagatttctctatgaaggaagtgaagacttttgctgtttgccaacctttgga
gtaatcccttcacaggcatccatgagtgggctggcaaatgttccagggctgagtattgat
tttacaaggctgctgcatggtgaacagtacctggaagtatacaaacctcttccaacttca
gggcagttgacgttcacagccaccatcgcagatgtccttgataaaggttccggcgcagtc
atacttctggacgttcacacatactgtggcaaggatctcatatgctataatcagttttct
atatttattgttggggctggaggatttggtggaaagaggacatcagataaagccaagcca
acagcaaatccacctagcagagcgccagatgccgtactgagtgatgtcacaagtgctgat
caggctgcattgtatcggctcagtggtgactggaaccctttgcacattgaccctaatttt
gcagtccttggaggttttcagaaacccatattacatggactgtgctcatttggatttgct
ggtagacatgtgttaaagcagtttgctgataacgatgtaacaaagtttaaagcaattaag
gtgcgatttgcaaaaccagttcttccaggccaaaccctgcaaacagagatgtggaaagaa
ggaaaccgaatctacctccagaccaaggtcaaagagactggacagatcgccattgctggt
gcatatgtggacctcacgttggctgctcaactatccccctccaacgagctcgcggaggct
acagagctccggagtgatcttgtcttcgaggaaataatccgtcgtattaaagatcttgga
gaagagatggtggcgaaggtaaacgccatctttcagtgggacatcacaaaagatgggaag
acggtggcacagtggactatcaacttgaagaatggatctggtgaagcgtacaaggggccg
gcacggggtcaggtggacacaacttttactgtttctgatactgatttcatggagattgta
atcggaaagctgaatcctcaaaaggcattcttttctggcaagctgaaagtgaaaggcaat
atcatgctgagccagaagttggagctcattctgaaggaccatgcaaaactttga
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