Pleurodeles waltl (Iberian ribbed newt): 138299917
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Entry
138299917 CDS
T10800
Symbol
HSD11B1
Name
(RefSeq) 11-beta-hydroxysteroid dehydrogenase 1 isoform X1
KO
K15680
corticosteroid 11-beta-dehydrogenase isozyme 1 [EC:
1.1.1.146
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl00140
Steroid hormone biosynthesis
pwl00980
Metabolism of xenobiotics by cytochrome P450
pwl01100
Metabolic pathways
Module
pwl_M00109
C21-Steroid hormone biosynthesis, progesterone => cortisol/cortisone
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
138299917 (HSD11B1)
09111 Xenobiotics biodegradation and metabolism
00980 Metabolism of xenobiotics by cytochrome P450
138299917 (HSD11B1)
Enzymes [BR:
pwl01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.146 11beta-hydroxysteroid dehydrogenase
138299917 (HSD11B1)
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Paralog
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Motif
Pfam:
adh_short
adh_short_C2
KR
DUF1776
Shikimate_DH
THF_DHG_CYH_C
NAD_binding_2
FMO-like
2-Hacid_dh_C
ADH_zinc_N
NmrA
Motif
Other DBs
NCBI-GeneID:
138299917
NCBI-ProteinID:
XP_069094729
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All DBs
Position
6:488655155..488893946
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AA seq
312 aa
AA seq
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MCMPSSHPRRLRAKDTTDTMGLLLKLIVASLGIFLALYFYTGQDDFNPEMLRGKRVIVTG
ASSGIGEQMAYHLARMGAHVFITARTEEKLKKVVSKCLELGAATAHYIPGSMDDMAFAER
VVKEAVKSMGGLDFLILNHIGYTYFNYFDGNVDHIRKLLEINLLSYVTMTVTALPMLKES
GGSIIVVSSVAGKYGSPFSVPYSTTKFALDGFFSSLRQEFHFQKTNVSITLCVLSYIDTD
SAKNAVASVINAPAAPKEECALALIKGGALRQREVYYQYQAAKIPLLLRDWAPDFLDYIV
RKNYNVEKIDKQ
NT seq
939 nt
NT seq
+upstream
nt +downstream
nt
atgtgcatgccaagttcgcaccccaggcgactcagagccaaggacacaaccgacaccatg
ggtctactcctgaagctgattgtcgcatccctgggcatattcctcgccctctacttctac
accgggcaggacgattttaacccggagatgctaagaggtaagcgtgtgattgtcactgga
gccagctctggcattggggagcagatggcctaccacttggcgcgtatgggggcccatgtt
ttcatcacagcaaggacggaggagaagctgaagaaggtggtttcaaaatgcctagagttg
ggagctgcaacagctcattatattccgggaagtatggatgacatggcatttgccgaacgg
gtggtgaaggaggccgtgaagtccatgggggggttagatttcctgattttgaaccacatt
ggatatacctactttaactatttcgatgggaatgttgaccacattcgaaaactgctggag
atcaatctcctgagttatgtcaccatgactgtcacagcattgccaatgttgaaggaaagt
ggtggcagcatcatcgttgtttcatcagtggcaggaaaatacggatcccctttttcagtt
ccatattccacaaccaagttcgcgcttgatgggtttttcagctctctgagacaagagttt
cactttcagaagacaaatgtctccatcaccctttgtgtcctgagttacattgacacagat
tcagcaaaaaatgcagtcgccagtgttatcaatgcgccagccgccccaaaagaagagtgt
gcccttgcccttatcaaaggaggagccctccgtcaacgagaagtatactaccaataccaa
gccgccaaaattcctctattgctcagagactgggcacctgacttcttggactacattgtg
cgtaaaaattacaatgtggagaaaattgacaaacagtag
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