Pleurodeles waltl (Iberian ribbed newt): 138304088
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Entry
138304088 CDS
T10800
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
pwl Pleurodeles waltl (Iberian ribbed newt)
Pathway
pwl04120
Ubiquitin mediated proteolysis
pwl04144
Endocytosis
pwl04330
Notch signaling pathway
Brite
KEGG Orthology (KO) [BR:
pwl00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
138304088 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
138304088 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
138304088 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
pwl04131
]
138304088 (ITCH)
04121 Ubiquitin system [BR:
pwl04121
]
138304088 (ITCH)
Enzymes [BR:
pwl01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
138304088 (ITCH)
Membrane trafficking [BR:
pwl04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
138304088 (ITCH)
Ubiquitin system [BR:
pwl04121
]
Ubiquitin ligases (E3)
HECT type E3
138304088 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
Gene cluster
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
138304088
NCBI-ProteinID:
XP_069099915
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Position
7:complement(365504154..366284114)
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AA seq
888 aa
AA seq
DB search
MRILLSLDTPITSGFLIGCDPARDMEGSWSRPGGVNGLTMKSQLQVTIISAKLKDTRKNW
FGPSPYVEVSVDGQSKKTERCNNTHSPKWKQHLTVIVSPSSKLLFRVWSYQTLKSDVLLG
SSTLNIHDTLKANNMKLEEVVVSLQLVGDKEPAEVIGDLSVCLDGMHVDPDHLLNGDATF
SSGTAQPEGSQAQSETVALSTETNTSENLEVADIGDSRTANSGSSPVLTNGGFKSSRPPR
PIRPPPPTPRRPTSSVPETNGPSSVALPTVTPNSQPQRNPEGEASPSLAVPPVSQQVSPV
NPAAQPVASVMQGPLPPGWEQRVDQHGRMYFVDHVEKRTTWDRPEPLPPGWERRVDNMNR
IYYVDHITRTTTWQRPTLESVRNYEQWQLQRNQLQGAMQQFNQRFIYGNQDYPGQNKEFD
PLGRLPVGWEKRTDSNGRVYYVNHTTRITQWEDPRTQGHLNEKPLPEGWEMRFTVDGIPY
FVDHNRKTTTYIDPRTGKSALDNGPQIAYVRDFKAKVQYFKFWCQQLAMPQHIKISVTRK
TLFEDSFQQIMSFNPQDLRRRLWVIFPGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYA
GKDNYCLQINPASYINPDHLKYFRFIGRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLN
DLETVDPEFYNSLIWIKENNIEECGLEMFFSVDKEILGEIQSQELKPDGSNILVTEENKE
EYIKLVAEWRLSRGVEDQTQAFFEGFNEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQR
HAIYRHYTRTSKQIIWFWQFVKEMDNEKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFC
VEKVGKENWLPRSHTCFNRLDLPPYKSYEQLKEKLLFAIEETEGFGQE
NT seq
2667 nt
NT seq
+upstream
nt +downstream
nt
atgcgaatcctgctcagtttggacacacccatcacgtctgggttcttaattggttgtgac
ccagcccgtgatatggagggcagttggtcaagacctggaggtgttaatggattgacaatg
aaatcgcagctccaagtcacaataatttctgcaaagcttaaggacacaaggaagaactgg
tttggaccgagcccttacgtggaagtgtccgtggatgggcagtccaaaaagacagaaaga
tgtaacaatacacatagtccgaaatggaagcaacatctcacagtaatcgtgtcaccatca
agtaaattactattccgggtgtggagttatcagactttgaaatctgatgttttactgggg
agttccactttaaatatacatgacactttaaaggcaaacaatatgaaactggaagaggtg
gtagtgtccctacaactagttggtgacaaggagccagcagaagtaataggagacctgtca
gtttgtcttgatgggatgcacgtagatcctgatcacttgcttaacggggatgcaacgttt
agctcaggtactgcacagcccgaaggttcacaagcacaaagtgaaaccgttgcattgagc
acagagacaaatacctcggagaaccttgaagttgctgacatcggtgacagcagaacagcg
aacagtggtagttcaccagtattaaccaatggtggattcaaatcatccaggccaccgaga
cctatacgtccgcctccaccaacacctcgccgaccaacatcctctgttccagagacgaat
ggtccaagttcagtagcgttgccaactgtaactccaaattcacaaccgcagagaaatcct
gaaggcgaggcatcaccctcgttggctgtaccccctgtatctcagcaagtctcgcctgtg
aatcctgcagcacaaccagttgcttcggtaatgcaaggaccattacctcccggttgggag
cagagagtggatcagcacgggcgaatgtattttgtagatcacgttgagaaaagaactact
tgggatcggccagaacctcttcctcccggatgggaaaggcgtgttgacaacatgaacaga
atttattacgttgaccatatcacccgaacaacaacctggcagcgacctacacttgaatca
gtgcggaattatgagcagtggcagctccaacgtaatcagctacagggagcgatgcaacag
tttaaccagcgattcatctatgggaatcaagattatccaggtcaaaataaagagtttgat
cctcttggacgattaccagtcgggtgggagaaaaggacagacagcaatggtagagtgtat
tatgtcaaccatactacacgaattactcagtgggaagaccccaggacgcaagggcatctg
aatgaaaaaccattgccagaagggtgggaaatgagatttacagttgatggtattccatat
tttgtggatcataatagaaaaactacaacgtacattgatcctcgcactgggaaatctgcc
ttagacaacggacctcaaatagcctatgtaagagacttcaaagcaaaggtccagtatttc
aagttctggtgtcagcaactggcaatgccacagcacataaagatttcagtgaccaggaag
accttgtttgaggactcatttcagcagatcatgagtttcaaccctcaggatctaagaaga
cgattatgggttattttcccaggtgaagaaggtttggattatggtggcgtggcaagagaa
tggttctttcttttgtcacacgaagtgctgaacccaatgtactgcctgtttgaatatgca
gggaaggacaactattgcctacagatcaaccctgcgtcttacatcaaccctgaccacctg
aaatacttccgcttcattggccggtttatagcaatggctttgttccatggcaagtttata
gacactggtttctctctaccgttctataagcgaattctaaataaaccagttggactcaat
gatttggaaactgtggatccagagttttacaactctctcatctggataaaagaaaacaac
atagaagaatgtggtttagaaatgtttttctcagttgataaagagatcctcggtgaaatt
cagagccaggagttgaaaccagatggcagcaacattctggtcactgaagaaaataaagag
gaatatataaaattggtggcagaatggagactctcaagaggggtggaagatcagactcag
gctttttttgagggattcaatgaaattcttccacagcaatacttacagtacttcgatgcc
aaagaactagaagtgctcctatgtggaatgcaagaaattgacttgaatgactggcaaagg
catgccatctataggcattacacaaggacaagcaagcagataatttggttttggcagttt
gtgaaagaaatggacaatgaaaaacgcatgcgacttctacagtttgtcactggaacctgc
agattacctgttggtggatttgctgacctcatggggagtaatggtcctcagaagttttgt
gttgaaaaagtggggaaagaaaattggctaccacgaagtcatacttgtttcaaccgcctg
gacctgccaccctacaaaagctatgaacagctcaaggaaaaactcctttttgcaatagaa
gaaacagaaggatttgggcaggagtaa
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