Puma yagouaroundi (jaguarundi): 121010320
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Entry
121010320 CDS
T07555
Symbol
PTPN11
Name
(RefSeq) tyrosine-protein phosphatase non-receptor type 11 isoform X1
KO
K07293
tyrosine-protein phosphatase non-receptor type 11 [EC:
3.1.3.48
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu04014
Ras signaling pathway
pyu04072
Phospholipase D signaling pathway
pyu04148
Efferocytosis
pyu04360
Axon guidance
pyu04625
C-type lectin receptor signaling pathway
pyu04630
JAK-STAT signaling pathway
pyu04650
Natural killer cell mediated cytotoxicity
pyu04660
T cell receptor signaling pathway
pyu04670
Leukocyte transendothelial migration
pyu04722
Neurotrophin signaling pathway
pyu04920
Adipocytokine signaling pathway
pyu04931
Insulin resistance
pyu05168
Herpes simplex virus 1 infection
pyu05205
Proteoglycans in cancer
pyu05208
Chemical carcinogenesis - reactive oxygen species
pyu05211
Renal cell carcinoma
pyu05220
Chronic myeloid leukemia
pyu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04014 Ras signaling pathway
121010320 (PTPN11)
04630 JAK-STAT signaling pathway
121010320 (PTPN11)
04072 Phospholipase D signaling pathway
121010320 (PTPN11)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
121010320 (PTPN11)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
121010320 (PTPN11)
04660 T cell receptor signaling pathway
121010320 (PTPN11)
04670 Leukocyte transendothelial migration
121010320 (PTPN11)
09156 Nervous system
04722 Neurotrophin signaling pathway
121010320 (PTPN11)
09158 Development and regeneration
04360 Axon guidance
121010320 (PTPN11)
09160 Human Diseases
09161 Cancer: overview
05205 Proteoglycans in cancer
121010320 (PTPN11)
05208 Chemical carcinogenesis - reactive oxygen species
121010320 (PTPN11)
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
121010320 (PTPN11)
09162 Cancer: specific types
05220 Chronic myeloid leukemia
121010320 (PTPN11)
05211 Renal cell carcinoma
121010320 (PTPN11)
09167 Endocrine and metabolic disease
04931 Insulin resistance
121010320 (PTPN11)
09180 Brite Hierarchies
09181 Protein families: metabolism
01009 Protein phosphatases and associated proteins [BR:
pyu01009
]
121010320 (PTPN11)
Enzymes [BR:
pyu01000
]
3. Hydrolases
3.1 Acting on ester bonds
3.1.3 Phosphoric-monoester hydrolases
3.1.3.48 protein-tyrosine-phosphatase
121010320 (PTPN11)
Protein phosphatases and associated proteins [BR:
pyu01009
]
Protein tyrosine phosphatases (PTPs)
Class I PTPs (Classical)
Non-receptor PTPs
121010320 (PTPN11)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Y_phosphatase
SH2
SH2_1
PTP-SAK
Tc-R-P
DSPc
Y_phosphatase3
PTPlike_phytase
PTP-NADK
Motif
Other DBs
NCBI-GeneID:
121010320
NCBI-ProteinID:
XP_040299771
LinkDB
All DBs
Position
Unknown
AA seq
597 aa
AA seq
DB search
MTSRRWFHPNITGVEAENLLLTRGVDGSFLARPSKSNPGDFTLSVRRNGAVTHIKIQNTG
DYYDLYGGEKFATLAELVQYYMEHHGQLKEKNGDVIELKYPLNCADPTSERWFHGHLSGK
EAEKLLTEKGKHGSFLVRESQSHPGDFVLSVRTGDDKGESNDGKSKVTHVMIRCQELKYD
VGGGERFDSLTDLVEHYKKNPMVETLGTVLQLKQPLNTTRINAAEIESRVRELSKLAETT
DKVKQGFWEEFETLQQQECKLLYSRKEGQRQENKNKNRYKNILPFDHTRVVLHDGDPNEP
VSDYINANIIMPEFETKCNNSKPKKSYIATQGCLQNTVNDFWRMVFQENSRVIVMTTKEV
ERGKSKCVKYWPDECALKEYGVMRVRNVKESAAHDYTLRELKLSKVGQALLQGNTERTVW
QYHFRTWPDHGVPSDPGGVLDFLEEVHHKQESIMDAGPVVVHCSAGIGRTGTFIVIDILI
DIIREKGVDCDIDVPKTIQMVRSQRSGMVQTEAQYRFIYMAVQHYIETLQRRIEEEQKSK
RKGHEYTNIKYSLTDQTSGDQSPLPPCTPTPSCAEMREDNARVYENVGLMQQQKSFR
NT seq
1794 nt
NT seq
+upstream
nt +downstream
nt
atgacatcgcggagatggtttcacccaaacatcactggcgtggaggcagaaaacctgctg
ttgacaagaggagttgatggcagttttttggcgaggcccagtaaaagtaaccctggagac
ttcaccctttctgtcagaagaaatggagctgtcacccacatcaagattcagaacaccggt
gattactatgacctgtacggaggggagaagtttgccactctggctgagctggtccagtat
tacatggaacaccacgggcaattaaaagagaagaatggagatgttattgagctcaaatat
cctttgaactgtgcagaccctacctctgaaaggtggtttcatggacacctctctgggaaa
gaagcagagaaattattgacggagaaaggaaaacacggcagctttctggtacgagagagc
cagagccatcctggagattttgttctctctgtccgaactggtgatgacaaaggggaaagc
aacgatggcaagtctaaagtgacccacgttatgatccgctgtcaggaactgaaatatgat
gttggtggaggagaacggtttgactctttgacagatctcgtggagcattacaagaagaac
cccatggtggaaacattgggcacagtgctacaactcaagcagcccctcaacacaacacgc
atcaatgctgctgaaatagaaagccgggttcgagaactaagcaaattagctgagaccaca
gataaagtcaaacaaggcttttgggaagaatttgagacactacagcaacaggagtgcaaa
cttctctacagcagaaaagagggtcagagacaagaaaataagaacaaaaatagatataaa
aacatcctacccttcgatcataccagagttgtcctccatgatggtgatcccaatgagcct
gtttcagattacatcaatgcaaatattatcatgcctgagtttgaaaccaaatgcaacaat
tcaaagcccaaaaagagttacattgccacacaaggctgcctgcaaaacacggtgaatgac
ttctggcggatggtgtttcaagaaaactcgcgagtgattgtcatgacgacgaaagaagtg
gagagaggaaagagtaaatgtgtcaaatactggcctgacgagtgtgctctaaaagaatat
ggggtcatgcgtgttaggaacgtcaaagaaagcgccgctcatgactatacgttaagagaa
cttaaactttcgaaggttggacaagctctactccaggggaatacagagagaaccgtgtgg
caataccactttcggacctggccggaccacggagtgcccagtgaccccgggggcgtgctg
gacttcctggaggaggtccaccataagcaagagagcattatggacgcggggcctgtggta
gttcactgcagtgctggaattggccggacagggacgttcattgtgattgatatccttatt
gacatcatcagagagaaaggtgtcgactgcgacatcgatgttcccaagaccattcagatg
gtgcggtctcagaggtcagggatggtccagacggaagctcagtaccgcttcatctacatg
gccgttcagcattacattgaaacactacagcgcaggattgaagaagagcagaaaagcaag
aggaaagggcacgaatatacaaatattaagtattctctcacggaccagacaagtggagat
cagagtcccctcccgccttgtactccaacaccatcctgcgcagaaatgagagaagataat
gctagagtctatgaaaacgtaggtctgatgcagcagcagaaaagtttcagatga
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