Puma yagouaroundi (jaguarundi): 121010992 Help Entry 121010992         CDS       T07555                                  Symbol JAK3 Name (RefSeq) tyrosine-protein kinase JAK3   KO K11218   Janus kinase 3 [EC:2.7.10.2] Organism pyu  Puma yagouaroundi (jaguarundi) Pathway pyu04062   Chemokine signaling pathway pyu04151   PI3K-Akt signaling pathway pyu04217   Necroptosis pyu04550   Signaling pathways regulating pluripotency of stem cells pyu04630   JAK-STAT signaling pathway pyu04658   Th1 and Th2 cell differentiation pyu04659   Th17 cell differentiation pyu05161   Hepatitis B pyu05162   Measles pyu05166   Human T-cell leukemia virus 1 infection pyu05169   Epstein-Barr virus infection pyu05200   Pathways in cancer pyu05203   Viral carcinogenesis pyu05223   Non-small cell lung cancer pyu05340   Primary immunodeficiency Brite KEGG Orthology (KO) [BR:pyu00001]  09130 Environmental Information Processing   09132 Signal transduction    04630 JAK-STAT signaling pathway     121010992 (JAK3)    04151 PI3K-Akt signaling pathway     121010992 (JAK3)  09140 Cellular Processes   09143 Cell growth and death    04217 Necroptosis     121010992 (JAK3)   09144 Cellular community - eukaryotes    04550 Signaling pathways regulating pluripotency of stem cells     121010992 (JAK3)  09150 Organismal Systems   09151 Immune system    04658 Th1 and Th2 cell differentiation     121010992 (JAK3)    04659 Th17 cell differentiation     121010992 (JAK3)    04062 Chemokine signaling pathway     121010992 (JAK3)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     121010992 (JAK3)    05203 Viral carcinogenesis     121010992 (JAK3)   09162 Cancer: specific types    05223 Non-small cell lung cancer     121010992 (JAK3)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     121010992 (JAK3)    05161 Hepatitis B     121010992 (JAK3)    05162 Measles     121010992 (JAK3)    05169 Epstein-Barr virus infection     121010992 (JAK3)   09163 Immune disease    05340 Primary immunodeficiency     121010992 (JAK3)  09180 Brite Hierarchies   09181 Protein families: metabolism    01001 Protein kinases [BR:pyu01001]     121010992 (JAK3) Enzymes [BR:pyu01000]  2. Transferases   2.7  Transferring phosphorus-containing groups    2.7.10  Protein-tyrosine kinases     2.7.10.2  non-specific protein-tyrosine kinase      121010992 (JAK3) Protein kinases [BR:pyu01001]  Non-receptor tyrosine kinases   JAK family [OT]    121010992 (JAK3) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  PK_Tyr_Ser-Thr Pkinase FERM_F2 SH2_1 FERM_F1 Jak1_Phl ABC1 Kdo Kinase-like FERM_C_FAK1 Haspin_kinase Motif Other DBs NCBI-GeneID:  121010992 NCBI-ProteinID:  XP_040300825 LinkDB All DBs Position Unknown AA seq 1106 aa AA seqDB search MAPPSEETPLIPQRSCSLSSSEAGALHVLLPPRGPGPPQRLSFSFGDHSAEELCVWAAKA SGILPVYHSLFALATEDLSYWYPPSHIFSVEDASTQVLLYRLRFYFPNWFGLEKCHRFGL RKDLASAILDLPVLEHLFAQHRNDLVSGRLAVGLSLKEQGECLSLAVLDLARMAREQAQQ PEELLKTVSYKACLPPDLRDLIQGLSFVTRKRIRRTVRRALGRVTACQADRHSLMAKYIM DLERLDPARAAETFLVSLPGAAGGQDAPGLLRVAGDSGIHWSPGGHEALQPFCDFPEIVD ISIKQAPRVGPAGEHRLVTVTRTDNQILEAEFPGLPAALSFVALVDGYFRLTSDSRHFFC KEVAPPRLLEEVAEQCHGPITLDFAINKLKAGGSLPGSYVLRRSPQDFDSFLLTVCVQTP LGPDYKGCLIRCDPTGTFSLAGLGRPHSSLRELLAACWDAGLHVDGVALSLTSCCAPRPK EKSNLIVVRRGCSTPTTSLVWPQSQCQLSQMTFHKIPADSLEWHENLGHGSFTKIYRGCR HEAVDGEARETEVLLKVMDAKHRNCMESFLEAASLMSQVSYQHLVLLHGVCMAGDSVMVQ EFVRLGALDTYLRKSGHLVPASWKLQVIKQLAYALNYLEDKGLPHGNVSARKVLLAREGA DGNLPFIKLSDPGVSPTVLSLEMLTDRIPWVAPECLQEARTLGLEADKWGFGATVWEVFS GIPMPISTLDPAKKLQFYEERQHLPAPKWMELATLIQQCMAYEPGQRPSFRAIIRDLNSL ITSDYELLSDPTPGALAPRDGLWNGAQLYACQDPTIFEERHLKYISQLGKGNFGSVELCC YDPLGDNTGALVAVKQLQHSGPDQQRDFQREIQILKALHSDFIVKYRGVSYGPGRQSLRL VMEYLPSGCLRDFLQRHRARLDASRLLLYASQICKGMEYLGSRRCVHRDLAARNILVESE THVKIADFGLAKLLPLDKDYYVVREPGQSPIFWYAPESLSDNIFSRQSDVWSFGVVLYEL FTYGNKNCSPSAEFLRMMGWERDVPALCRLLELLAEGQRLPAPPACPGEVHELMKLCWAP SPQDRPTFSALGPQLDTLWSGSRGVA NT seq 3321 nt NT seq  +upstreamnt  +downstreamnt atggcgcctccaagtgaggagacgcccctgatccctcagcgttcctgcagcctctcgtct tcagaggctggtgccctgcacgtgctgctgccccctcggggccccggacccccacaacgc ctgtccttctcctttggggaccattcagctgaagagctatgtgtttgggctgctaaggcc agtggcatcctgcctgtgtaccactccctctttgctctggccacggaggacctgtcctac tggtaccccccgagccacatcttctccgtggaggatgcaagcacccaagtcctgctctac aggctccgcttttacttccccaactggtttgggttggagaaatgccaccgcttcgggcta cggaaggacttggccagtgccatccttgacttgccagtcctggagcatctcttcgcccag caccgaaatgacctggtgagcggccgcctcgccgtgggcctcagtctcaaggagcagggt gaatgtctcagcctggcagtgctggacctggctcggatggcccgtgagcaggctcagcag cctgaggagctgctgaagaccgtcagctacaaggcctgcctgccccccgatctgcgcgac ctgatccagggcctgagcttcgtgacgcggaagcgtatccggaggactgtgcgccgggcc ctgggccgcgtgaccgcctgccaggctgacaggcactcgctcatggccaagtacatcatg gacctggagaggctggacccggccagggccgccgagaccttcctcgtgagcctccccggg gctgctggtggtcaagatgctccggggctgctccgagtggctggtgacagcggcatccac tggagtccgggaggacacgaggccctccagcccttctgcgactttccagaaattgtggac atcagcatcaagcaggctcctcgtgtgggccccgccggggagcaccgcctggtcaccgtc accaggacggacaaccagatcctggaggccgagttcccggggctgcccgcggccctgtcc tttgtggcgctcgtggacggctacttccggctgacttccgactccaggcacttcttctgc aaggaggttgcgccgccgcggctgctggaggaggtggccgagcagtgccacggtcccatc accctggattttgccatcaacaagctcaaggccgggggctcccttcccggatcctatgtt ctccgccgcagcccccaggatttcgacagcttcctcctcactgtctgcgtccagaccccc ctgggtcctgattacaagggctgcctcatccggtgtgaccccactggaaccttctccctg gctggcctcggccggccccacagcagtcttcgagagctcttggcagcctgctgggatgct gggctgcacgtggatggggttgcgctgagcctcacctcctgctgcgcccccagacccaaa gaaaagtccaacctgatcgtggtgcggagaggttgcagcactcccacaacatcccttgtt tggccccaatcccagtgccagctgagtcagatgacgtttcacaagatccctgctgacagc ctggagtggcatgagaacctgggtcatgggtccttcaccaagatttaccgaggttgtcgc catgaggctgtggacggggaagcccgggagacagaggtgctactcaaagtgatggatgcc aagcacagaaactgcatggagtccttcctggaagcagcgagcctgatgagccaagtgtcg tatcagcacctcgtgttgctccacggcgtgtgcatggctggagacagtgtcatggtgcag gaatttgtgcgcctgggagccctggatacatatctgcgcaagtctggccacctggtacca gccagctggaagctgcaggtgatcaaacagctggcctatgccctcaactatctggaagac aaaggcctcccccatggcaatgtctcagcccggaaggtgctcttggctcgggagggggct gacgggaacctgcccttcatcaagttgagtgaccctggtgtcagccccactgtgctgagc ctggagatgctcaccgacaggatcccctgggtggcccctgagtgtctccaggaggcccgg acccttggcttggaagctgacaagtggggtttcggtgccacagtctgggaagtgttcagc gggatcccgatgcccatcagtaccctggatcctgccaagaagctccagttttacgaggaa cggcagcaccttcctgcccccaagtggatggagctggccacactgatccaacagtgcatg gcctatgagccaggccagaggccctccttccgcgccatcatccgtgacctgaacagcctc atcacttcagattatgagctcctctcagaccccacacctggtgccttggcgccccgtgat gggctgtggaatggcgcccagctctacgcctgccaggaccctaccatttttgaggagaga catctcaagtacatctcacagctaggcaagggcaactttggcagcgtggagctgtgctgc tatgacccgctgggcgacaacacgggggccctagtggctgtgaagcagcttcagcacagc gggccagaccagcagagggacttccagcgggagatccagatcctcaaagccctccacagc gacttcattgtcaagtaccgcggtgtcagctatggcccgggccgccagagcctgcggctg gtgatggagtacctgcccagcggctgcctgcgcgacttcctgcagcgacaccgcgcgcgc ctcgacgccagccgcctgctcctctacgcctcgcagatctgcaagggcatggagtacctg ggctcccgccgctgcgtgcaccgcgacctggcggcccgtaacatcctggtggagagcgag acgcacgtcaagatcgccgactttggcctcgccaagctgctgccgctcgacaaagactac tacgtggtccgcgagcccggccagagccccatcttctggtacgccccagagtccctctct gacaacatcttctcgcgtcagtcggacgtctggagcttcggggtcgtcctgtacgagctt ttcacctacggcaacaagaattgcagcccctcagccgagttcctccggatgatgggatgg gagcgagacgtccccgccctctgccgcctcctggagctgctggctgagggccagaggctg cccgcgcctcctgcctgccccggtgaggttcatgagctcatgaagctgtgctgggccccg agcccgcaagaccggccaacattcagtgccctgggcccccagctggatacactgtggagt ggaagccggggggtggcatag

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