Puma yagouaroundi (jaguarundi): 121013412
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Entry
121013412 CDS
T07555
Symbol
MAP3K5
Name
(RefSeq) mitogen-activated protein kinase kinase kinase 5 isoform X1
KO
K04426
mitogen-activated protein kinase kinase kinase 5 [EC:
2.7.11.25
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu01524
Platinum drug resistance
pyu04010
MAPK signaling pathway
pyu04071
Sphingolipid signaling pathway
pyu04141
Protein processing in endoplasmic reticulum
pyu04210
Apoptosis
pyu04530
Tight junction
pyu04668
TNF signaling pathway
pyu04714
Thermogenesis
pyu04722
Neurotrophin signaling pathway
pyu04932
Non-alcoholic fatty liver disease
pyu04936
Alcoholic liver disease
pyu05010
Alzheimer disease
pyu05012
Parkinson disease
pyu05014
Amyotrophic lateral sclerosis
pyu05016
Huntington disease
pyu05017
Spinocerebellar ataxia
pyu05022
Pathways of neurodegeneration - multiple diseases
pyu05208
Chemical carcinogenesis - reactive oxygen species
pyu05417
Lipid and atherosclerosis
pyu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04141 Protein processing in endoplasmic reticulum
121013412 (MAP3K5)
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121013412 (MAP3K5)
04668 TNF signaling pathway
121013412 (MAP3K5)
04071 Sphingolipid signaling pathway
121013412 (MAP3K5)
09140 Cellular Processes
09143 Cell growth and death
04210 Apoptosis
121013412 (MAP3K5)
09144 Cellular community - eukaryotes
04530 Tight junction
121013412 (MAP3K5)
09150 Organismal Systems
09156 Nervous system
04722 Neurotrophin signaling pathway
121013412 (MAP3K5)
09159 Environmental adaptation
04714 Thermogenesis
121013412 (MAP3K5)
09160 Human Diseases
09161 Cancer: overview
05208 Chemical carcinogenesis - reactive oxygen species
121013412 (MAP3K5)
09164 Neurodegenerative disease
05010 Alzheimer disease
121013412 (MAP3K5)
05012 Parkinson disease
121013412 (MAP3K5)
05014 Amyotrophic lateral sclerosis
121013412 (MAP3K5)
05016 Huntington disease
121013412 (MAP3K5)
05017 Spinocerebellar ataxia
121013412 (MAP3K5)
05022 Pathways of neurodegeneration - multiple diseases
121013412 (MAP3K5)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
121013412 (MAP3K5)
05418 Fluid shear stress and atherosclerosis
121013412 (MAP3K5)
09167 Endocrine and metabolic disease
04936 Alcoholic liver disease
121013412 (MAP3K5)
04932 Non-alcoholic fatty liver disease
121013412 (MAP3K5)
09176 Drug resistance: antineoplastic
01524 Platinum drug resistance
121013412 (MAP3K5)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pyu01001
]
121013412 (MAP3K5)
Enzymes [BR:
pyu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.11 Protein-serine/threonine kinases
2.7.11.25 mitogen-activated protein kinase kinase kinase
121013412 (MAP3K5)
Protein kinases [BR:
pyu01001
]
Serine/threonine kinases: STE group
STE11 family
121013412 (MAP3K5)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
MAP3K_TRAF_bd
Pkinase
HisK-N-like
PK_Tyr_Ser-Thr
ASK_PH
TPR-S
DRHyd-ASK
Kinase-like
Pkinase_fungal
Motif
Other DBs
NCBI-GeneID:
121013412
NCBI-ProteinID:
XP_040305011
LinkDB
All DBs
Position
Unknown
AA seq
1367 aa
AA seq
DB search
MSAEAGEGITFSVPPLAEGGSCRRGAAAAAAEGEESQLPPPPPGSFWNVESAAAPGTGCP
AATSGSSATRCRGNSGGGGGRRTTVAYVINEASQGQLVMAESEALQSLREACETVGATLE
TVHFGKLDFGETAVLDRFYNADIAVVEMSDAFRQPSLFYHLGVRESFSMANNIILYCDNN
SDSLQSLKEIICQKNTMCTGNYTFVPYMITPHNKVYCCDSSFMKGLTELMQPNFELLLGP
ICLPLVDRFIQLLKVAQASSSQYFRESILNDIRKARNLYTGKELAAELARIRQRVDNIEV
LTADIVINLLLSYRDIQDYDSIVKLVETLEKLPTFDLASHHHVKFHYAFALNRRNLPGDR
AKALDIMIPLVQSEGQVASDMYCLVGRIYKDMFLDSNFLDTESRDYGASWFKKAFESEPS
LQSGINYAVLLLAAGHQFESSFELRKVGVKLSSLLGKKGNLEKLQSYWEVGFFLGASVLA
NDHMRVIQASEKLFKLKTPAWYLKSIVETILIYKHFVKLTTEQPVAKQELVDFWMDFLVE
ATKTDVTVVRFPVLILEPTKIYQPSYLSINNEVEEKTISIWHVLPDDKKGIHEWNFSASS
VRGVSISKFEERCCFLYVLHNSDDFQIYFCTELHCKKFFEMVNTITEEKGRSTEEGDCEG
DSLEYDYEYDENGDRVVLGKGTYGIVYAGRDLSNQVRIAIKEIPERDSRYSQPLHEEIAL
HKHLKHKNIVQYLGSFSENGFIKIFMEQVPGGSLSALLRSKWGPLKDNEQTIGFYTKQIL
EGLKYLHDNQIVHRDIKGDNVLINTYSGVLKISDFGTSKRLAGINPCTETFTGTLQYMAP
EIIDKGPRGYGKAADIWSLGCTIIEMATGKPPFYELGEPQAAMFKVGMFKVHPEIPESMS
AEAKAFILKCFEPDPDKRACANDLLIDEFLKVSSKKKKTQPKLSALSAGSNAEYLRSISL
PVPVLVEDTSSSSEYGSVSPDTELKVDPFSFKTRAKSCGERDVKGIRTLFLGIPDENFED
HSAPPSPEEKDSGFFMLRKDSERRATLHRILTEDQDKVVRNLMESLAQGAEEPKLKWEHI
TTLIASLREFVRSTDRKIIATTLSKLKLELDFDSHGISQVQVVLFGFQDAVNKVLRNHNI
KPHWMFALDSIIRKAVQTAITILVPELRPHFSLASESDTADQEDLDAEDEREEQPSNQTV
QRPHAVIEDAVATSGVSTLSSTVSHDSQNAHRSLNVQLGRMKIETNRLLEELVQKEKELQ
ALLHQAIEEKDHEIKHLKLKSQPIDIPGVPVCHRDSLGTNAEESELAEWLREKGADEDTI
SRFLAEDYSLEDVLYYVTRDDLKCLRLRGGILCTLWKAITDFRDKQT
NT seq
4104 nt
NT seq
+upstream
nt +downstream
nt
atgagcgcggaggcgggcgagggcatcactttctccgtgccacccttagccgagggcggc
agctgccggaggggagcagcggcggcggcggccgagggcgaggagagccagctaccaccg
ccgccgccgggcagcttctggaacgtggagagtgccgccgccccgggcaccgggtgtccc
gctgccacctctgggagcagcgccacccggtgccggggcaactctggtggcggaggcggc
cgacggaccacggtggcatatgtgatcaacgaagcgagccaggggcagctggtgatggcc
gagagcgaggccctgcagagcctgcgggaggcgtgcgagacggtgggcgccaccctggag
accgtgcattttggtaaactggactttggggaaaccgcggtgctggatcgtttctacaat
gcagatatcgctgtggtggagatgagtgacgccttccgacagccatcattgttttaccac
cttggggtcagagagagtttcagcatggccaacaacatcatcctctactgtgataataat
tcagactctctgcagtcactgaaggaaatcatttgccagaagaatactatgtgcactggg
aactacacattcgttccttacatgatcactccacataataaagtctactgctgcgatagc
agcttcatgaaggggttgacagagctcatgcaaccgaacttcgagctgcttcttggaccc
atttgcttacctcttgtggaccgtttcattcaacttctgaaggtggcacaagcaagttcc
agccagtatttccgggaatctatactcaatgatatcaggaaagctcgtaatttatacact
ggtaaagaattggcagctgaattggcaaggattcggcagcgagtagataatattgaagtc
ttgacagcagatattgtcataaacctgttactttcctacagagatatccaggactatgat
tctattgtgaagctggtagagacgttagaaaagctgccaacctttgatttggcttcccat
caccatgtgaagtttcattatgcatttgcactgaataggagaaatctccctggagacaga
gcaaaagctcttgatattatgattcccctggtgcaaagtgaagggcaagttgcttcagat
atgtattgcctagtgggccgaatctacaaagatatgtttttggactctaatttcctggac
actgaaagtagagactatggagcttcttggttcaaaaaggcatttgaatctgagccatca
ctacagtcaggaattaattatgcggtccttctcctggcagctgggcaccagtttgaatct
tcctttgagctccggaaagttggggtgaagctaagtagccttcttggtaaaaagggaaat
ttagaaaaactccagagctactgggaagttggattttttctgggtgccagtgtcctggcc
aatgaccacatgagagtcatccaagcatctgaaaagctttttaaactgaagacaccagca
tggtacctcaagtctattgtagagacaattttgatatataagcattttgtgaaactgact
acagagcagcctgtggccaaacaggagctggtggacttctggatggatttcctggtggag
gccacaaagacagatgttactgtagttaggtttccggtgttaatattagaaccaactaaa
atctatcagccttcatatttgtctatcaacaatgaagttgaggaaaagacaatatctatt
tggcatgtgcttcctgatgacaagaaaggtatacatgagtggaattttagtgcttcttct
gtcaggggagtgagtatttctaaatttgaagaacgatgctgttttctttatgtgcttcat
aattctgacgatttccaaatctatttctgtacagaacttcattgtaaaaagttttttgaa
atggtgaacaccattaccgaagagaaggggagaagcacagaggaaggtgattgtgaaggt
gactccttggagtatgactacgaatatgatgagaacggagacagagttgttttaggaaag
ggcacttacgggattgtctacgcaggccgagacctgagcaaccaagtcagaattgctata
aaggaaatcccagaaagagatagcagatactcccagcccctacatgaagaaatagcattg
cataagcatctgaagcataaaaatattgtccagtatctgggctctttcagtgagaacggt
ttcatcaaaatcttcatggagcaggtcccaggaggaagtctttcagctctccttcgttcc
aaatggggcccattgaaggacaatgagcaaacaattggcttctatacaaagcaaatactt
gaaggattaaaatacctccatgacaatcagatagtccatcgggatataaagggtgacaat
gtgttgattaatacctacagtggcgttctcaagatctcagacttcgggacatcaaagagg
cttgctggcattaacccatgtactgaaacttttactggtacccttcagtatatggcacca
gaaatcatagacaaaggaccaagaggctacgggaaagcagcagacatttggtctttgggc
tgcacgatcatcgaaatggccacagggaaaccacctttctatgaactgggagaaccacaa
gcagctatgttcaaggtgggaatgtttaaagtccacccggagatcccagagtccatgtcc
gcagaggccaaggcgttcatattgaaatgttttgaaccggaccccgacaagagagcctgt
gctaacgacttgcttattgacgagttcttaaaagtttcaagcaaaaagaagaagacgcaa
cctaagctttcagccctctcagctggatcaaatgcagagtatcttagaagcatatccttg
cccgtgcccgtcttggtggaggacaccagcagcagcagtgaatacggctcggtttctccg
gacacggagttgaaggtggatcccttctctttcaagacgagagccaaatcctgtggagag
cgagatgtaaaaggaatacggacactctttctgggcattccagacgaaaatttcgaagac
cacagcgctccaccctcccctgaagagaaagattctggattctttatgctgaggaaggac
agtgagagacgggccactcttcacaggatcctgaccgaagaccaagacaaagttgtgagg
aacttaatggaatctttggctcagggagctgaagaacctaaactaaaatgggaacacatc
acaaccctcattgcaagcctcagagaatttgtgagatccacggaccgaaaaatcatagcc
accacactgtctaagctgaagctagaacttgactttgacagccatggcattagtcaagtt
caggtggtactcttcggttttcaagatgccgtcaataaagttcttcggaatcataacatc
aagccacactggatgtttgccttagacagtatcatccgaaaggcggtgcagacggccatc
accattctggtgccagaactgaggccacatttcagcctcgcatctgagagtgataccgcg
gatcaagaagacttggatgcggaagatgagcgtgaggaacagccttcaaaccaaaccgtc
caaagacctcatgctgtcattgaagatgccgtggctacctcaggggtgagcacgctcagt
tctactgtatcccatgactcccaaaatgctcaccgatcactcaatgtgcagcttggaagg
atgaaaatagaaactaatagattactggaagaattggttcagaaagagaaagaattacaa
gcactccttcatcaagctattgaagaaaaagaccatgaaattaaacacctgaagcttaag
tcccaaccaatagatattcctggagtgcctgtgtgtcaccgggattctctgggcacaaat
gctgaagagtctgaacttgctgaatggctgagagaaaagggagctgatgaagacactata
agtcggtttctggctgaggattattcactagaggatgttctctactatgttacacgtgat
gatttaaaatgcctgagactaaggggaggaatactctgcacgctgtggaaggccatcact
gactttcgagacaaacagacttga
DBGET
integrated database retrieval system
