Herpailurus yagouaroundi (jaguarundi): 121016977 Help Entry 121016977         CDS       T07555                                  Symbol ADCY1 Name (RefSeq) adenylate cyclase type 1   KO K08041   adenylate cyclase 1 [EC:4.6.1.1] Organism pyu  Herpailurus yagouaroundi (jaguarundi) Pathway pyu00230   Purine metabolism pyu01100   Metabolic pathways pyu01522   Endocrine resistance pyu04015   Rap1 signaling pathway pyu04020   Calcium signaling pathway pyu04022   cGMP-PKG signaling pathway pyu04024   cAMP signaling pathway pyu04062   Chemokine signaling pathway pyu04072   Phospholipase D signaling pathway pyu04081   Hormone signaling pyu04082   Neuroactive ligand signaling pyu04114   Oocyte meiosis pyu04211   Longevity regulating pathway pyu04213   Longevity regulating pathway - multiple species pyu04261   Adrenergic signaling in cardiomyocytes pyu04270   Vascular smooth muscle contraction pyu04371   Apelin signaling pathway pyu04540   Gap junction pyu04611   Platelet activation pyu04713   Circadian entrainment pyu04714   Thermogenesis pyu04720   Long-term potentiation pyu04723   Retrograde endocannabinoid signaling pyu04724   Glutamatergic synapse pyu04725   Cholinergic synapse pyu04727   GABAergic synapse pyu04750   Inflammatory mediator regulation of TRP channels pyu04911   Insulin secretion pyu04912   GnRH signaling pathway pyu04913   Ovarian steroidogenesis pyu04914   Progesterone-mediated oocyte maturation pyu04915   Estrogen signaling pathway pyu04916   Melanogenesis pyu04918   Thyroid hormone synthesis pyu04921   Oxytocin signaling pathway pyu04923   Regulation of lipolysis in adipocytes pyu04925   Aldosterone synthesis and secretion pyu04926   Relaxin signaling pathway pyu04927   Cortisol synthesis and secretion pyu04928   Parathyroid hormone synthesis, secretion and action pyu04934   Cushing syndrome pyu04935   Growth hormone synthesis, secretion and action pyu04970   Salivary secretion pyu04971   Gastric acid secretion pyu04972   Pancreatic secretion pyu04976   Bile secretion pyu05032   Morphine addiction pyu05142   Chagas disease pyu05146   Amoebiasis pyu05163   Human cytomegalovirus infection pyu05166   Human T-cell leukemia virus 1 infection pyu05200   Pathways in cancer pyu05207   Chemical carcinogenesis - receptor activation pyu05414   Dilated cardiomyopathy Brite KEGG Orthology (KO) [BR:pyu00001]  09100 Metabolism   09104 Nucleotide metabolism    00230 Purine metabolism     121016977 (ADCY1)  09130 Environmental Information Processing   09132 Signal transduction    04015 Rap1 signaling pathway     121016977 (ADCY1)    04371 Apelin signaling pathway     121016977 (ADCY1)    04020 Calcium signaling pathway     121016977 (ADCY1)    04072 Phospholipase D signaling pathway     121016977 (ADCY1)    04024 cAMP signaling pathway     121016977 (ADCY1)    04022 cGMP-PKG signaling pathway     121016977 (ADCY1)   09133 Signaling molecules and interaction    04082 Neuroactive ligand signaling     121016977 (ADCY1)    04081 Hormone signaling     121016977 (ADCY1)  09140 Cellular Processes   09143 Cell growth and death    04114 Oocyte meiosis     121016977 (ADCY1)   09144 Cellular community - eukaryotes    04540 Gap junction     121016977 (ADCY1)  09150 Organismal Systems   09151 Immune system    04611 Platelet activation     121016977 (ADCY1)    04062 Chemokine signaling pathway     121016977 (ADCY1)   09152 Endocrine system    04911 Insulin secretion     121016977 (ADCY1)    04923 Regulation of lipolysis in adipocytes     121016977 (ADCY1)    04912 GnRH signaling pathway     121016977 (ADCY1)    04913 Ovarian steroidogenesis     121016977 (ADCY1)    04915 Estrogen signaling pathway     121016977 (ADCY1)    04914 Progesterone-mediated oocyte maturation     121016977 (ADCY1)    04921 Oxytocin signaling pathway     121016977 (ADCY1)    04926 Relaxin signaling pathway     121016977 (ADCY1)    04935 Growth hormone synthesis, secretion and action     121016977 (ADCY1)    04918 Thyroid hormone synthesis     121016977 (ADCY1)    04928 Parathyroid hormone synthesis, secretion and action     121016977 (ADCY1)    04916 Melanogenesis     121016977 (ADCY1)    04925 Aldosterone synthesis and secretion     121016977 (ADCY1)    04927 Cortisol synthesis and secretion     121016977 (ADCY1)   09153 Circulatory system    04261 Adrenergic signaling in cardiomyocytes     121016977 (ADCY1)    04270 Vascular smooth muscle contraction     121016977 (ADCY1)   09154 Digestive system    04970 Salivary secretion     121016977 (ADCY1)    04971 Gastric acid secretion     121016977 (ADCY1)    04972 Pancreatic secretion     121016977 (ADCY1)    04976 Bile secretion     121016977 (ADCY1)   09156 Nervous system    04724 Glutamatergic synapse     121016977 (ADCY1)    04727 GABAergic synapse     121016977 (ADCY1)    04725 Cholinergic synapse     121016977 (ADCY1)    04720 Long-term potentiation     121016977 (ADCY1)    04723 Retrograde endocannabinoid signaling     121016977 (ADCY1)   09157 Sensory system    04750 Inflammatory mediator regulation of TRP channels     121016977 (ADCY1)   09149 Aging    04211 Longevity regulating pathway     121016977 (ADCY1)    04213 Longevity regulating pathway - multiple species     121016977 (ADCY1)   09159 Environmental adaptation    04713 Circadian entrainment     121016977 (ADCY1)    04714 Thermogenesis     121016977 (ADCY1)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     121016977 (ADCY1)    05207 Chemical carcinogenesis - receptor activation     121016977 (ADCY1)   09172 Infectious disease: viral    05166 Human T-cell leukemia virus 1 infection     121016977 (ADCY1)    05163 Human cytomegalovirus infection     121016977 (ADCY1)   09174 Infectious disease: parasitic    05146 Amoebiasis     121016977 (ADCY1)    05142 Chagas disease     121016977 (ADCY1)   09165 Substance dependence    05032 Morphine addiction     121016977 (ADCY1)   09166 Cardiovascular disease    05414 Dilated cardiomyopathy     121016977 (ADCY1)   09167 Endocrine and metabolic disease    04934 Cushing syndrome     121016977 (ADCY1)   09176 Drug resistance: antineoplastic    01522 Endocrine resistance     121016977 (ADCY1) Enzymes [BR:pyu01000]  4. Lyases   4.6  Phosphorus-oxygen lyases    4.6.1  Phosphorus-oxygen lyases (only sub-subclass identified to date)     4.6.1.1  adenylate cyclase      121016977 (ADCY1) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Guanylate_cyc AC_N Adcy_cons_dom HNOBA DUF6688 Motif Other DBs NCBI-GeneID:  121016977 NCBI-ProteinID:  XP_040310956 LinkDB All DBs Position Unknown AA seq 903 aa AA seqDB search MYGVFVRILAERSQRKAFLQARNCIEDRLRLEDENEKQERLLMSLLPRNVAMEMKEDFLK PPERIFHKIYIQRHDNVSILFADIVGFTGLASQCTAQELVKLLNELFGKFDELATENHCR RIKILGDCYYCVSGLTQPKTDHAHCCVEMGLDMIDTITSVAEATEVDLNMRVGLHTGRVL CGVLGLRKWQYDVWSNDVTLANVMEAAGLPGKVHITKTTLACLNGDYEVEPGHGHERNSF LKAHNIETFFIVPSHRRKIFPGLILSDIKPAKRMKFKTVCYLLVQLMHCRKMFKAEIPFS NVLTCEDDDKRRALRTASEKLRNRSSFSANAVYTTPGTRVNRYIGRLLEARQMELEMADL DFFTLKYKQAERERKYHQLQDEYFTSAVVLALVLAALFGLIYLLIIPQNLVLLLLLAFCI CFLVACVLYLHVTRVQCFPGCLTIQIRTVLCIFVVVLIYSVAQGCVVGCLPWSWSSTPNG SLVVLTPSGRNAVLPAAPCESAPHALLCGLVGTLPLAVFLRVSSLPKMILLFVLTTSYIL VLELSGYTRAPGGGMASGRSFEPIMAILLFSCTLALHARQVDVKLRLDYLWAAQAEEERD DMERVKLDNKRILFNLLPAHVAQHFLMSNPRNMDLYYQSYSQVGVMFASIPNFDDFYIEL DGNNMGVECLRLLNEIIADFDELMDKDFYKDLEKIKTIGSTYMAAVGLAPTTGTKAKKGI SSHLSTLADFAIEMFDVLDEINYQSYNDFVLRVGINVGPVVAGVIGARRPQYDIWGNTVN VASRMDSTGVQGRIQVTEEVHRLLRRGTYRFVCRGKVSVKGKGEMLTYFLEGRTDGNGSQ ARERKVCGYGRAGLQGRLGTGPPPVSSMAGLPVRAGMGALQGSGLPPCPHGQHLPPGAAG KEA NT seq 2712 nt NT seq  +upstreamnt  +downstreamnt atgtatggggtgtttgtgcgcatcctggccgagcgctcccagcggaaagccttcctgcaa gcccggaactgcatcgaagatcggctgaggctggaggatgagaacgagaagcaggagcgg ctgctcatgagccttctgccccggaatgttgccatggagatgaaggaggacttcctgaag ccccccgagaggattttccacaagatttacatccagcggcatgacaacgtgagcatcctc tttgcggacattgtgggcttcacgggcctggcgtcgcagtgcacggcacaggagctggtc aagctcctcaacgagctgttcggcaagtttgatgaactggccacggagaatcactgtcgc cgcatcaagatcctaggggactgttactactgtgtgtccggcctcacccagcccaagacc gaccacgcccactgctgcgtggagatgggcctggacatgatcgacaccatcacgtctgtg gccgaggccactgaggtggacctgaacatgcgcgtggggctgcacacaggcagggtcctc tgcggggtcctgggcctgcgcaagtggcagtacgacgtgtggtccaacgacgtgaccctg gccaacgtcatggaggcggctggcctacctgggaaggtccacatcacgaagacgacccta gcgtgcctgaacggggactacgaggtggagccgggtcacggacacgagaggaacagtttt ctgaaagctcacaacatcgagaccttcttcatcgtgccgtcacatcggcggaagatattt ccagggctgatcctctctgacataaaaccagccaagaggatgaagttcaagaccgtgtgc tacctgctcgtgcagctgatgcactgtcggaagatgttcaaggcagagatcccgttctct aacgtcctgacgtgtgaggacgacgacaagcggagggcactgagaaccgcgtcggagaaa ctgcgaaaccgctcgtcgttctccgcaaacgccgtctacaccaccccgggcacgcgcgtc aacaggtacattggccgcctcctggaagcgcgccagatggagctggagatggcggacctg gacttcttcaccctcaagtacaagcaggctgagcgggagcgcaagtatcaccagctccag gacgagtattttaccagcgccgtcgttctggccctcgtcctggccgccttgttcggcctc atctacctgctcatcatcccacagaacctggtcctcctgctgctgctggccttctgtatc tgcttcctggtggcctgcgtcctgtatctgcacgtcacccgggtccagtgttttccaggg tgcctgacgattcagatccgcaccgtcttgtgtatcttcgtcgtggtcttaatctactcc gtggcccaaggatgtgtggtgggctgcctgccctggtcctggagctccacccccaacggg tccctggtggtcctgacacccagcggccgcaacgccgtgctgcctgccgcgccctgtgag tcggcgccccacgccctgctctgcggccttgtgggtaccctcccgctggctgtcttcctg cgggtgtcctccctgcccaaaatgatcctgctctttgtgctcacgacgtcctacatcctg gtcctggagctcagcggctacaccagggcccccgggggcggcatggcatcggggcgcagt ttcgagccgatcatggccatcctgctgttttcctgcaccctggccctgcacgcccgtcag gtggacgtcaagctgcggctggactacctctgggcagcacaggcagaggaggagagagat gacatggagagggtgaagttggacaacaagaggattctcttcaacctcctgccggcccac gtggctcagcacttcctcatgtccaacccccgcaacatggacctgtactaccagtcctac tcacaggtgggtgtcatgtttgcttccatccccaacttcgacgacttctacatcgagctg gatggcaacaacatgggggtggagtgtctgcgtctcctgaacgagatcatcgcagacttc gacgagctcatggacaaagacttttacaaggacttggagaagatcaagaccatcgggagc acctacatggccgctgtggggctggcgcccaccactgggaccaaggccaagaagggcatc tcctcccacctgagcacactggctgacttcgccattgagatgtttgacgtcctggatgaa atcaactaccagtcttacaacgactttgtgctccgtgtgggcatcaacgtgggccctgtg gtggccggggtgatcggggctcggaggccacagtacgacatctgggggaacacagtcaac gtggccagtcgaatggacagcaccggcgtccagggcagaatccaggtgaccgaggaggtt caccggctgctgcgccgggggacctaccgcttcgtgtgccgcgggaaggtcagcgtcaag ggcaagggtgagatgctgacgtacttcctggaaggcaggacggacggaaacggctcccaa gccagggagcggaaagtgtgtggctacgggcgagccggcctccagggcagactgggtaca ggcccacccccggtgtcctccatggccggcctcccggtcagagccgggatgggggctctg cagggctcagggctccccccctgcccccacggccagcacctgccccccggagcagctggg aaggaggcttag

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