Puma yagouaroundi (jaguarundi): 121022112
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Entry
121022112 CDS
T07555
Symbol
CACNA1C
Name
(RefSeq) voltage-dependent L-type calcium channel subunit alpha-1C isoform X1
KO
K04850
voltage-dependent calcium channel L type alpha-1C
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu04010
MAPK signaling pathway
pyu04020
Calcium signaling pathway
pyu04022
cGMP-PKG signaling pathway
pyu04024
cAMP signaling pathway
pyu04260
Cardiac muscle contraction
pyu04261
Adrenergic signaling in cardiomyocytes
pyu04270
Vascular smooth muscle contraction
pyu04713
Circadian entrainment
pyu04720
Long-term potentiation
pyu04723
Retrograde endocannabinoid signaling
pyu04724
Glutamatergic synapse
pyu04725
Cholinergic synapse
pyu04726
Serotonergic synapse
pyu04727
GABAergic synapse
pyu04728
Dopaminergic synapse
pyu04742
Taste transduction
pyu04911
Insulin secretion
pyu04912
GnRH signaling pathway
pyu04921
Oxytocin signaling pathway
pyu04924
Renin secretion
pyu04925
Aldosterone synthesis and secretion
pyu04927
Cortisol synthesis and secretion
pyu04929
GnRH secretion
pyu04930
Type II diabetes mellitus
pyu04934
Cushing syndrome
pyu04935
Growth hormone synthesis, secretion and action
pyu05010
Alzheimer disease
pyu05020
Prion disease
pyu05022
Pathways of neurodegeneration - multiple diseases
pyu05031
Amphetamine addiction
pyu05207
Chemical carcinogenesis - receptor activation
pyu05410
Hypertrophic cardiomyopathy
pyu05412
Arrhythmogenic right ventricular cardiomyopathy
pyu05414
Dilated cardiomyopathy
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04010 MAPK signaling pathway
121022112 (CACNA1C)
04020 Calcium signaling pathway
121022112 (CACNA1C)
04024 cAMP signaling pathway
121022112 (CACNA1C)
04022 cGMP-PKG signaling pathway
121022112 (CACNA1C)
09150 Organismal Systems
09152 Endocrine system
04911 Insulin secretion
121022112 (CACNA1C)
04929 GnRH secretion
121022112 (CACNA1C)
04912 GnRH signaling pathway
121022112 (CACNA1C)
04921 Oxytocin signaling pathway
121022112 (CACNA1C)
04935 Growth hormone synthesis, secretion and action
121022112 (CACNA1C)
04924 Renin secretion
121022112 (CACNA1C)
04925 Aldosterone synthesis and secretion
121022112 (CACNA1C)
04927 Cortisol synthesis and secretion
121022112 (CACNA1C)
09153 Circulatory system
04260 Cardiac muscle contraction
121022112 (CACNA1C)
04261 Adrenergic signaling in cardiomyocytes
121022112 (CACNA1C)
04270 Vascular smooth muscle contraction
121022112 (CACNA1C)
09156 Nervous system
04724 Glutamatergic synapse
121022112 (CACNA1C)
04727 GABAergic synapse
121022112 (CACNA1C)
04725 Cholinergic synapse
121022112 (CACNA1C)
04728 Dopaminergic synapse
121022112 (CACNA1C)
04726 Serotonergic synapse
121022112 (CACNA1C)
04720 Long-term potentiation
121022112 (CACNA1C)
04723 Retrograde endocannabinoid signaling
121022112 (CACNA1C)
09157 Sensory system
04742 Taste transduction
121022112 (CACNA1C)
09159 Environmental adaptation
04713 Circadian entrainment
121022112 (CACNA1C)
09160 Human Diseases
09161 Cancer: overview
05207 Chemical carcinogenesis - receptor activation
121022112 (CACNA1C)
09164 Neurodegenerative disease
05010 Alzheimer disease
121022112 (CACNA1C)
05020 Prion disease
121022112 (CACNA1C)
05022 Pathways of neurodegeneration - multiple diseases
121022112 (CACNA1C)
09165 Substance dependence
05031 Amphetamine addiction
121022112 (CACNA1C)
09166 Cardiovascular disease
05410 Hypertrophic cardiomyopathy
121022112 (CACNA1C)
05412 Arrhythmogenic right ventricular cardiomyopathy
121022112 (CACNA1C)
05414 Dilated cardiomyopathy
121022112 (CACNA1C)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
121022112 (CACNA1C)
04934 Cushing syndrome
121022112 (CACNA1C)
09180 Brite Hierarchies
09183 Protein families: signaling and cellular processes
04040 Ion channels [BR:
pyu04040
]
121022112 (CACNA1C)
Ion channels [BR:
pyu04040
]
Voltage-gated cation channels
Calcium channel, voltage-gated (Cav)
121022112 (CACNA1C)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
Ion_trans
CAC1F_C
Ca_chan_IQ
GPHH
PKD_channel
Motif
Other DBs
NCBI-GeneID:
121022112
NCBI-ProteinID:
XP_040318950
LinkDB
All DBs
Position
Unknown
AA seq
2193 aa
AA seq
DB search
MNANAAAGLAPEHIPTPGAALSWQAAIDAARQAKLMGSAGNATISTISSTQRKRQQYGKP
KKQGSTTATRPPRALLCLTLKNPIRRACISIVEWKPFEIIILLTIFANCVALAIYIPFPE
DDSNATNSNLERVEYLFLIIFTVEAFLKVIAYGLLFHPNAYLRNGWNLLDFIIVVVGLFS
AILEQATKADGANALGGKGAGFDVKALRAFRVLRPLRLVSGVPSLQVVLNSIIKAMVPLL
HIALLVLFVIIIYAIIGLELFMGKMHKTCYNQEGIADVPAEDDPSPCALETGHGRQCQNG
TVCKPGWDGPKHGITNFDNFAFAMLTVFQCITMEGWTDVLYWMQDAMGYELPWVYFVSLV
IFGSFFVLNLVLGVLSGEFSKEREKAKARGDFQKLREKQQLEEDLKGYLDWITQAEDIDP
ENEDEGMDEEKPRNRSTPAGLLDQKKGKFAWFSHSTETHVSMPTSETESVNTENVAGGDI
EGENCGARLAHRISKSKFSRYWRRWNRFCRRKCRAAVKSNVFYWLVIFLVFLNTLTIASE
HYNQPHWLTEVQDTANKALLALFTAEMLLKMYSLGLQAYFVSLFNRFDCFIVCGGILETI
LVETKIMSPLGISVLRCVRLLRIFKITRYWNSLSNLVASLLNSVRSIASLLLLLFLFIII
FSLLGMQLFGGKFNFDEMQTRRSTFDNFPQSLLTVFQILTGEDWNSVMYDGIMAYGGPSF
PGMLVCIYFIILFICGNYILLNVFLAIAVDNLADAESLTSAQKEEEEEKERKKLARTASP
EKKQEIMEKPAVEETKEEKIELKSITADGESPPTTKINMDDLQPNENEDKSPYPNPENTG
EDDEEEPEMPVGPRPRPLSELHLKEKAVPMPEASAFFIFSPNNRFRLQCHRIVNDTIFTN
LILFFILLSSISLAAEDPVQHTSFRNHILFYFDIVFTTIFTIEIALKILGNADYVFTSIF
TLEIILKMTAYGAFLHKGSFCRNYFNILDLLVVSVSLISFGIQSSAINVVKILRVLRVLR
PLRAINRAKGLKHVVQCVFVAIRTIGNIVIVTTLLQFMFACIGVQLFKGKLYTCSDSSKQ
TEAECKGNYITYKDGEVDHPIIQPRSWENSKFDFDNVLAAMMALFTVSTFEGWPELLYRS
IDSHTEDKGPIYNYRVEISIFFIIYIIIIAFFMMNIFVGFVIVTFQEQGEQEYKNCELDK
NQRQCVEYALKARPLRRYIPKNQHQYKVWYVVNSTYFEYLMFVLILLNTICLAMQHYGQS
CLFKIAMNILNMLFTGLFTVEMILKLIAFKPKGYFSDPWNVFDFLIVIGSIIDVILSETN
HYFCDAWNTFDALIVVGSIVDIAITEVNPAEHTQCSPFMNAEENSRISITFFRLFRVMRL
VKLLSRGEGIRTLLWTFIKSFQALPYVALLIVMLFFIYAVIGMQVFGKIALNDTTEINRN
NNFQTFPQAVLLLFRCATGEAWQDIMLACMPGKKCAPESEPSNSTEGETPCGSSFAVFYF
ISFYMLCAFLIINLFVAVIMDNFDYLTRDWSILGPHHLDEFKRIWAEYDPEAKGRIKHLD
VVTLLRRIQPPLGFGKLCPHRVACKRLVSMNMPLNSDGTVMFNATLFALVRTALRIKTEG
NLEQANEELRAIIKKIWKRTSMKLLDQVVPPAGDDEVTVGKFYATFLIQEYFRKFKKRKE
QGLVGKPSQRNALSLQAGLRTLHDIGPEIRRAISGDLTAEEELDKAMKEAVSAASEDDIF
RRAGGLFGNHVSYYQSDGRSAFPQTFTTQRPLHINKAGNSQGDTESPSHEKLVDSTFTPS
SYSSTGSNANINNANNTALGRFPRPAGYPSAVSTVEGHGPPLSPAVRVQEAAWKLSSKRI
HCYDVLGRCHSRESQIAMVCQEEVSQDETYDVKISEDTEYCSEPSLISTEMLSYQDDENR
QLTPPEEDKRDIRQSPKRGFLRSASLGRRASFHLECLKRQKNQGGDISQKTVLPLHLVHH
QALAVAGLSPLLQRSHSPSTSPRPCATPPATPSSRGWPPQPIPTLRLEGAESNEKLNSSF
PSIHCSSWSGEPTPCGGGGSTIRRARPVSLTVPGQAGAQGRQFHGSASSLVEAVLISEGL
GQFAQDPKFIEVTTQELADACDMTIEEMENAADNILSGGAQQSPNGTLLPFVNCRDPGQD
RAEGQEGETCAPTLACRKSEEELQDSRAHVGSL
NT seq
6582 nt
NT seq
+upstream
nt +downstream
nt
atgaatgccaatgcggctgcggggctcgcccccgagcacatcccaacgcccggggcagcc
ttgtcctggcaggcagccatcgacgcggcccggcaggctaagctgatgggcagcgctggc
aatgcaaccatctccaccatcagctccacacagcggaagcggcagcaatatgggaaaccc
aagaagcagggcagcacgactgccacacgcccgccccgtgccctgctctgcctgactctg
aagaaccccatcaggagggcgtgcatcagcatcgtcgaatggaaaccatttgaaataatt
attttactgactatttttgccaattgtgtggccttagcgatctatattccctttccagaa
gatgactccaatgccaccaattccaacctggaacgagtggaatatctctttctcataatt
tttactgtggaagcatttttaaaagtaatagcctatggacttctctttcaccccaacgct
tacctccgcaatggctggaatttactagattttataattgtggttgtagggctttttagt
gcaattttagaacaagccaccaaagctgacggggcaaatgctctaggagggaaaggagct
ggatttgatgtgaaggcactgagggcattccgcgtgctgcgccccttgcggctggtgtct
ggagtcccaagtctccaagtcgttctgaattccattatcaaggccatggtccccctgctg
catattgccctgttagtgctatttgtcatcatcatctacgctatcattggcctggagctc
ttcatgggaaagatgcataagacctgctacaaccaggagggcatagcagatgttccagca
gaagatgatccttccccttgtgctctggagactggccatgggcggcagtgccagaatggc
actgtgtgcaagcctggctgggacgggcccaagcacggcatcaccaactttgacaatttt
gccttcgccatgttgacagtgttccagtgcatcaccatggagggctggacagatgtgcta
tactggatgcaggacgctatgggctatgagttaccctgggtgtattttgtcagtctggtc
atctttggatcctttttcgttctaaatctggttctcggtgtgttgagcggagagttttcc
aaagagagagagaaggccaaggctcggggagacttccagaagctgcgagagaagcagcag
ctggaagaggacctgaagggctacctggactggatcacccaggcagaggacatcgaccct
gagaacgaggatgaaggcatggatgaggagaagccccgaaacagaagcactccagcgggc
ttgcttgatcagaagaaagggaagtttgcttggtttagtcactccacagaaacccatgtg
agcatgcccacaagtgagaccgagtctgtcaacaccgaaaacgtggctggaggtgacatc
gagggagagaactgcggggccaggctggcccatcggatttccaaatcaaagttcagccgc
tactggcgtcggtggaatcggttctgcagaagaaagtgtcgtgctgcagtcaagtctaat
gtcttctactggcttgtgatcttcctggtgttcctcaacacactcaccattgcctcagaa
cattacaaccagccccactggctcacagaggtccaagacacagccaacaaggcactactg
gcccttttcactgcggagatgctgctaaagatgtacagcctgggcctgcaggcctacttt
gtgtccctcttcaaccgctttgactgcttcatcgtgtgtgggggcattctggagactatc
ctggtggagaccaagatcatgtctcccttgggcatctctgtgctgagatgtgtccggcta
ctgcggatatttaaaatcacaaggtactggaactccttaagcaacctggtggcatccttg
ctgaattctgtgcgctccattgcctccctgctgctactcctcttcctcttcatcatcatc
ttctccctcctggggatgcagctctttggaggaaagttcaactttgatgagatgcagact
cggaggagcacatttgataactttcctcagtccctcctcaccgtgtttcagatcctgacc
ggggaggactggaattcggtgatgtatgatgggatcatggcttatggcggcccctctttt
ccagggatgttagtctgtatttacttcatcatcctcttcatctgtggaaactatatccta
ctgaatgtgttcttggccattgctgtggacaatctggctgatgctgagagcctcacatct
gcccaaaaggaggaggaagaagagaaggagagaaagaagctggccaggactgccagccca
gagaagaagcaagagataatggaaaagccagctgtggaggaaaccaaggaggagaaaatt
gagctgaaatccattacagctgatggagagtccccacccaccaccaagatcaacatggat
gacctccagcccaatgaaaatgaagataagagtccctaccccaacccagaaaatacagga
gaagacgatgaagaggagcctgagatgcctgtgggcccccgcccacgaccactctctgag
ctgcaccttaaggaaaaggcagtgcccatgccagaagccagtgcatttttcatcttcagc
cccaacaacagatttcgcctccagtgccaccgcattgtcaatgacacgatcttcaccaac
ctgatcctcttcttcattctgctcagcagcatttccctggcagctgaggaccctgtccag
cacacctccttcaggaaccatattctgttttattttgacattgttttcactaccattttc
accattgaaattgctctgaagatcctaggcaatgcagactatgtcttcactagtatcttt
acattagaaattatccttaagatgactgcttatggggctttcctacacaagggctctttc
tgccggaactacttcaacatcttggacctgctggtggtcagcgtgtccctcatctccttt
ggcatccagtccagtgcaattaatgtggtgaagatcttgcgagttctgcgagtcctcagg
cccctgagggccatcaacagggccaaggggctaaagcacgtggtccagtgcgtgtttgtt
gccatccggaccatagggaatatcgtgattgtcaccacgctgctccagttcatgttcgcc
tgcatcggggtccagcttttcaagggaaagctctacacctgttcagatagttccaagcag
actgaggcggaatgcaagggtaactacatcacatacaaggatggggaagttgaccacccc
atcatccagcctcgcagctgggaaaacagcaagtttgactttgacaatgttctggcagcc
atgatggccctctttactgtctccacctttgaggggtggccagagctgctgtaccgctcc
atcgactcccacacagaagacaagggccccatctacaactaccgtgtggagatctccatc
tttttcatcatctacatcattatcattgccttcttcatgatgaacatcttcgtgggtttt
gtcatcgtcaccttccaggagcagggggagcaggaatacaagaactgtgaactggacaag
aaccagcgacagtgtgtggaatatgccctcaaggcccggcccctgcgaaggtacatcccc
aaaaaccagcaccagtacaaagtgtggtacgtggtcaactccacctactttgaatacctg
atgttcgtcctcatcctgctcaacaccatctgcttggcaatgcagcactatggccagagc
tgcctattcaaaatcgccatgaacatcctcaacatgctcttcactggcctcttcactgtg
gagatgattctgaagctcattgccttcaaacccaagggttactttagtgatccctggaat
gtttttgacttcctcatcgtaattggcagcataattgacgtcattctcagtgaaactaat
cactatttctgtgatgcatggaatacatttgacgccttgattgttgtgggtagcattgtt
gatatagcaatcaccgaggtaaacccagctgaacatacccaatgctctccctttatgaac
gcagaggagaactcccgcatctccatcaccttcttccgcctcttccgggtcatgcgcctg
gtcaagctgctaagccgtggggagggcatccggaccctgctgtggaccttcatcaagtcc
ttccaggctttgccctatgtggcccttctgatagtgatgctgttcttcatctacgcagtg
atcgggatgcaggtgtttgggaaaattgccctgaatgacaccacagagatcaaccggaac
aacaactttcagaccttcccccaagctgtgctccttctcttcaggtgtgccacaggggag
gcatggcaagacatcatgctggcctgcatgccagggaagaagtgtgcccccgagtcagag
cccagcaacagcacggaaggggaaacgccctgtggcagcagttttgccgtcttctacttc
atcagcttctacatgctctgtgccttcctgatcatcaacctctttgtagctgtcatcatg
gacaactttgactacctgacaagagactggtcaatccttggtccccatcatctggatgaa
tttaaaagaatctgggcagagtatgatcctgaagctaagggtcgtatcaaacacctagat
gtggtgaccctgctcaggcggattcagcccccactgggttttgggaagctgtgccctcac
cgcgtggcttgcaaacgtctggtctccatgaacatgcctctgaacagtgatgggactgtc
atgttcaatgccaccctgtttgccctagtccggacagccctgcggatcaaaacagaaggg
aacctagaacaagccaatgaggagctgcgggccataatcaagaagatctggaagcgtacc
agcatgaagctgctagaccaagtggtgccccctgcaggtgatgatgaggtcaccgttggc
aagttttatgctactttcctgatccaagagtacttccggaaattcaagaagcgcaaagag
cagggccttgtgggcaagccttcccaaaggaacgccctgtccttgcaggctggcttgcgc
acgctgcatgacattgggcctgagatccgacgggccatctctggagatctgacagctgag
gaggagctggacaaggccatgaaggaggctgtgtctgctgcctccgaagatgacatcttc
aggagggccggtggcctgttcggcaaccacgtcagctactaccaaagcgacggccggagc
gccttcccccagaccttcaccacccagcgcccactgcacatcaacaaggcgggtaacagc
caaggcgacaccgagtcgccatcccacgagaaactggtggactccaccttcacccccagc
agctactcgtccactggctccaacgccaacatcaacaatgccaacaacactgccctgggc
cgcttcccccgtcccgctggctaccccagcgcagtcagcaccgtggagggccatgggccc
cccttgtctcctgctgtccgggtacaggaggcagcatggaagctcagctccaagaggata
cattgctatgatgtgctgggacggtgccactcccgggagagccagatagccatggtgtgt
caggaggaggtctctcaggacgagacctatgacgtgaagataagtgaagacactgagtac
tgcagcgagcccagcctgatctccacagagatgctctcctatcaggatgatgaaaatcgg
caattaacaccaccggaggaggacaagagagatatccggcaatctccaaagaggggcttc
ctccgctctgcctcactaggtcgaagggcctccttccacctggaatgtctgaagcgacag
aagaatcaagggggagacatctctcagaagacagtcctgcccttgcatctggttcatcat
caggcattggcggtggcaggcctgagccccctcctccagagaagccattcccccagcaca
tcccccaggccctgtgccaccccaccagccactccaagcagccgaggctggcccccacag
cctatccccaccctgcggctggagggtgctgaatccaacgagaaactcaacagcagcttc
ccgtccatccactgcagctcctggtctggagagcccacaccctgtggtggaggtggcagc
accatccggagagcccggccagtgtccctcactgtgcccggccaggctggggcccagggc
aggcagttccacggcagtgccagcagcctggtagaagcggtcttgatttcagaaggactg
gggcagtttgctcaagatcccaagtttattgaggtcacaacccaggagctggctgacgcc
tgtgacatgaccatagaggagatggagaacgccgcagacaacatcctcagtgggggcgcc
cagcagagccccaatggcaccctactacctttcgttaactgcagggacccagggcaggac
agagcagagggccaagagggcgagacctgcgcgcccaccctggcgtgtcggaagagcgag
gaggagctccaggacagcagagcccacgtcggcagcctgtag
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integrated database retrieval system
