Puma yagouaroundi (jaguarundi): 121025386
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Entry
121025386 CDS
T07555
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu04064
NF-kappa B signaling pathway
pyu04380
Osteoclast differentiation
pyu04650
Natural killer cell mediated cytotoxicity
pyu04658
Th1 and Th2 cell differentiation
pyu04659
Th17 cell differentiation
pyu04660
T cell receptor signaling pathway
pyu05135
Yersinia infection
pyu05166
Human T-cell leukemia virus 1 infection
pyu05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
pyu05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
121025386 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
121025386 (LCK)
04660 T cell receptor signaling pathway
121025386 (LCK)
04658 Th1 and Th2 cell differentiation
121025386 (LCK)
04659 Th17 cell differentiation
121025386 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
121025386 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
121025386 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
121025386 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
121025386 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
121025386 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pyu01001
]
121025386 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
pyu03036
]
121025386 (LCK)
Enzymes [BR:
pyu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
121025386 (LCK)
Protein kinases [BR:
pyu01001
]
Non-receptor tyrosine kinases
SRC family
121025386 (LCK)
Chromosome and associated proteins [BR:
pyu03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
121025386 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
SH2_1
Haspin_kinase
SH3_16
SH3_3
Motif
Other DBs
NCBI-GeneID:
121025386
NCBI-ProteinID:
XP_040323864
LinkDB
All DBs
Position
Unknown
AA seq
520 aa
AA seq
DB search
MGVGGLTISGTMGCSCSSNPEDDWMENIDVCENCHYPIVPLDGKATLPMRNGSDVRDPLV
TYEGFNPPASPLQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEG
FIPFNFVAKANSLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGSFSLSVRD
FDQNQGEVVKHYKIRNLDKGGFYISPRITFPGLHELVRHYTNASDGLCTRLSRPCQTQKP
QKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQGSMSPDAFLAEA
NLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPPGIKLTINKLLDMAAQIA
EGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTAREGAKFPIKWTAP
EAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYRMVRPDNCPEEL
YHLMMLCWKERPEERPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1563 nt
NT seq
+upstream
nt +downstream
nt
atgggggttgggggcctgacaatctcagggaccatgggctgtagctgcagctcaaaccct
gaagatgactggatggaaaacatcgatgtgtgtgagaactgccattacccgatagtccca
ctggatggcaaggccacgctgcccatgcggaatggctctgatgtgagggatccactagtt
acctacgaaggcttcaatcccccagcctcaccattgcaagacaacctggttatcgctctg
cacagctatgagccctctcacgatggagacctgggcttcgagaagggtgaacagctccgt
atcctggagcagagcggcgagtggtggaaggcgcagtccctgaccacgggccaggaaggt
ttcatccccttcaacttcgtggccaaagcgaacagcctggagcccgaaccctggttcttc
aagaacctgagccgcaaggacgcggaacggcagctcctggcgcccgggaacacgcacggc
tccttcctgatccgggagagcgagagcaccgcgggatcgttttcactgtccgtgcgggac
ttcgaccagaaccagggagaggtggtgaaacattacaagatccgtaacctggacaaaggc
ggcttctacatctccccccgcatcacttttcctggcctgcacgagctggtccgccattac
accaatgcttcggacgggctgtgcacgcggttgagtcgcccctgccagacccagaagccc
cagaagccttggtgggaggacgagtgggaggttcccagggagacgctgaagctggtggag
cggctgggggctggccagttcggggaggtgtggatggggtactacaacgggcacacaaag
gtggcagtgaagagcctgaagcagggcagcatgtcccccgacgccttcctggccgaggcc
aacctcatgaagcagctacaacaccagaggctggtccggctctacgcggtggtcacccag
gagcccatctacatcatcacggaatacatggagaatgggagcctggtggatttcctcaag
acccctccaggcatcaagttgaccatcaacaaactcttggacatggcagcccaaattgca
gagggcatggcattcattgaagaacggaattacatccaccgtgacctgagggctgccaat
atcctggtgtcggacaccctgagctgcaagattgcagactttggcctagcacgcctcatt
gaggacaatgagtacacagccagggagggggccaagtttcccattaagtggacagcacca
gaagccattaactacgggacattcaccatcaagtcggacgtgtggtcttttgggatccta
ctgacggagattgtcacccatggccgcatcccttacccagggatgaccaatcctgaggtg
attcagaacctggagcgaggctaccgcatggtgcgacctgacaactgcccagaggagcta
taccacctcatgatgctgtgctggaaggagcggccagaggaacggcccacctttgactac
ctgcgcagcgtgctagaggacttcttcacggccacagagggccagtaccagccccagccc
tga
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