Puma yagouaroundi (jaguarundi): 121030909 Help Entry 121030909         CDS       T07555                                  Symbol CASP8 Name (RefSeq) caspase-8   KO K04398   caspase 8 [EC:3.4.22.61] Organism pyu  Puma yagouaroundi (jaguarundi) Pathway pyu01524   Platinum drug resistance pyu04115   p53 signaling pathway pyu04210   Apoptosis pyu04215   Apoptosis - multiple species pyu04217   Necroptosis pyu04620   Toll-like receptor signaling pathway pyu04621   NOD-like receptor signaling pathway pyu04622   RIG-I-like receptor signaling pathway pyu04623   Cytosolic DNA-sensing pathway pyu04625   C-type lectin receptor signaling pathway pyu04657   IL-17 signaling pathway pyu04668   TNF signaling pathway pyu04932   Non-alcoholic fatty liver disease pyu04936   Alcoholic liver disease pyu05010   Alzheimer disease pyu05016   Huntington disease pyu05022   Pathways of neurodegeneration - multiple diseases pyu05132   Salmonella infection pyu05134   Legionellosis pyu05142   Chagas disease pyu05145   Toxoplasmosis pyu05152   Tuberculosis pyu05160   Hepatitis C pyu05161   Hepatitis B pyu05162   Measles pyu05163   Human cytomegalovirus infection pyu05164   Influenza A pyu05165   Human papillomavirus infection pyu05167   Kaposi sarcoma-associated herpesvirus infection pyu05168   Herpes simplex virus 1 infection pyu05169   Epstein-Barr virus infection pyu05170   Human immunodeficiency virus 1 infection pyu05200   Pathways in cancer pyu05203   Viral carcinogenesis pyu05416   Viral myocarditis pyu05417   Lipid and atherosclerosis Brite KEGG Orthology (KO) [BR:pyu00001]  09130 Environmental Information Processing   09132 Signal transduction    04668 TNF signaling pathway     121030909 (CASP8)  09140 Cellular Processes   09143 Cell growth and death    04210 Apoptosis     121030909 (CASP8)    04215 Apoptosis - multiple species     121030909 (CASP8)    04217 Necroptosis     121030909 (CASP8)    04115 p53 signaling pathway     121030909 (CASP8)  09150 Organismal Systems   09151 Immune system    04620 Toll-like receptor signaling pathway     121030909 (CASP8)    04621 NOD-like receptor signaling pathway     121030909 (CASP8)    04622 RIG-I-like receptor signaling pathway     121030909 (CASP8)    04623 Cytosolic DNA-sensing pathway     121030909 (CASP8)    04625 C-type lectin receptor signaling pathway     121030909 (CASP8)    04657 IL-17 signaling pathway     121030909 (CASP8)  09160 Human Diseases   09161 Cancer: overview    05200 Pathways in cancer     121030909 (CASP8)    05203 Viral carcinogenesis     121030909 (CASP8)   09172 Infectious disease: viral    05170 Human immunodeficiency virus 1 infection     121030909 (CASP8)    05161 Hepatitis B     121030909 (CASP8)    05160 Hepatitis C     121030909 (CASP8)    05164 Influenza A     121030909 (CASP8)    05162 Measles     121030909 (CASP8)    05168 Herpes simplex virus 1 infection     121030909 (CASP8)    05163 Human cytomegalovirus infection     121030909 (CASP8)    05167 Kaposi sarcoma-associated herpesvirus infection     121030909 (CASP8)    05169 Epstein-Barr virus infection     121030909 (CASP8)    05165 Human papillomavirus infection     121030909 (CASP8)   09171 Infectious disease: bacterial    05132 Salmonella infection     121030909 (CASP8)    05134 Legionellosis     121030909 (CASP8)    05152 Tuberculosis     121030909 (CASP8)   09174 Infectious disease: parasitic    05145 Toxoplasmosis     121030909 (CASP8)    05142 Chagas disease     121030909 (CASP8)   09164 Neurodegenerative disease    05010 Alzheimer disease     121030909 (CASP8)    05016 Huntington disease     121030909 (CASP8)    05022 Pathways of neurodegeneration - multiple diseases     121030909 (CASP8)   09166 Cardiovascular disease    05417 Lipid and atherosclerosis     121030909 (CASP8)    05416 Viral myocarditis     121030909 (CASP8)   09167 Endocrine and metabolic disease    04936 Alcoholic liver disease     121030909 (CASP8)    04932 Non-alcoholic fatty liver disease     121030909 (CASP8)   09176 Drug resistance: antineoplastic    01524 Platinum drug resistance     121030909 (CASP8)  09180 Brite Hierarchies   09181 Protein families: metabolism    01002 Peptidases and inhibitors [BR:pyu01002]     121030909 (CASP8) Enzymes [BR:pyu01000]  3. Hydrolases   3.4  Acting on peptide bonds (peptidases)    3.4.22  Cysteine endopeptidases     3.4.22.61  caspase-8      121030909 (CASP8) Peptidases and inhibitors [BR:pyu01002]  Cysteine peptidases   Family C14: caspase family    121030909 (CASP8) BRITE hierarchy SSDB OrthologParalogGFIT Motif Pfam:  Peptidase_C14 DED PYRIN Motif Other DBs NCBI-GeneID:  121030909 NCBI-ProteinID:  XP_040331774 LinkDB All DBs Position Unknown AA seq 479 aa AA seqDB search MDFSKCLYNIGEQLGSDELASLKFLSLDYIPQKKQEPIKDALMLFQRLQEKRMLEESNLS FLKELLFRINRLDLLFNYLNTSKEAMEQELQIPGRAQIPPYRVMLFQISEDVNKLELRSF KFLLSQEISRCKVDDDMNLLDIFIEMEKRVILGERNLDTLKRICDQINKSLLKKITDYEE LSREGRMSLQRSPDELSNGEESLAMMALSDSLEEQDSESQTSDKVYRMKSKPRGYCLIFN NYDFSRARKDVPKLQNIKDRNGTNFDAEALSKTFSELHFEIVNFKDSTAKTICEVLKSYQ RMDHNNKDCFICCILSHGDKGIIYGSDGQEAPIYELTSYFTGSKCPSLAGKPKIFFIQAC QGDNYQRGIAVETDSEQKEDYLEMDSSFQKRYIPDEADFLLGMATVNNCVSYRNPTEGTW YIQSLCQSLRERCPRGEDILTILTEVNFEVSNKDDKKNMGKQMPQPTFTLRKKLFFPLN NT seq 1440 nt NT seq  +upstreamnt  +downstreamnt atggatttcagtaaatgtctgtataatattggggaacagctgggcagtgacgagctggcc tccctcaaattcctgagcctggactacatcccacaaaagaagcaagaacccatcaaagat gccttgatgttattccagagactccaggaaaagagaatgttggaggaaagcaacctgtcc ttcttgaaggagctgcttttccgaattaatagactggacctgctgttcaactacctgaac accagcaaggaagcgatggagcaggagcttcagataccaggcagagcccagatccctccc tacagggtcatgctttttcagatttcagaagatgtaaacaaattggaattgaggtcgttt aagtttcttttgagccaggagatctccagatgtaaagtggatgatgatatgaacttgctt gatattttcatagagatggaaaagagggtcatcctaggggaaagaaatttggacactctg aaaagaatctgtgaccaaatcaacaagagcctgctgaagaaaatcactgattatgaagaa ttaagcagagagggaagaatgagccttcaaagaagtccagatgaattgtcaaatggggag gaatccctggcaatgatggcattatcggactctctagaagaacaggacagtgagtcacag acatcggacaaagtttaccgaatgaaaagcaaacctcgtggatattgtttgatctttaac aattatgattttagcagagcacggaaggatgtgcccaaacttcagaacattaaggatagg aatggaacaaacttcgatgcagaagctttgagtaagacctttagtgagcttcattttgag attgtgaatttcaaagactctacagcaaagacaatctgtgaagttctgaaatcctaccaa agaatggaccataataacaaagattgcttcatctgctgtatcctctcccatggagacaaa ggcattatttatggctctgatgggcaggaagcccccatctatgagctgacttcttacttc actggttcaaagtgcccttcccttgcaggcaagcccaaaatcttttttattcaggcttgt caaggggataactaccagagaggtatagctgttgagactgactccgaacagaaggaagac tacttagaaatggactcatcatttcagaagagatatatcccagatgaggctgattttctg ctggggatggccactgtgaacaactgtgtttcctaccgaaaccctacggaggggacctgg tatatccagtcactttgccagagcctaagagaaagatgtcctaggggcgaagatatcctc accatccttactgaggtgaactttgaagtgagcaataaggatgacaagaaaaacatgggg aaacaaatgccacaacctactttcacactgaggaaaaaactcttcttccctcttaattga

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