KEGG   Puma yagouaroundi (jaguarundi): 121040857
Entry
121040857         CDS       T07555                                 
Symbol
CDK4
Name
(RefSeq) cyclin-dependent kinase 4 isoform X1
  KO
K02089  cyclin-dependent kinase 4 [EC:2.7.11.22]
Organism
pyu  Puma yagouaroundi (jaguarundi)
Pathway
pyu01522  Endocrine resistance
pyu04110  Cell cycle
pyu04115  p53 signaling pathway
pyu04151  PI3K-Akt signaling pathway
pyu04218  Cellular senescence
pyu04530  Tight junction
pyu04660  T cell receptor signaling pathway
pyu04933  AGE-RAGE signaling pathway in diabetic complications
pyu04934  Cushing syndrome
pyu05160  Hepatitis C
pyu05162  Measles
pyu05163  Human cytomegalovirus infection
pyu05164  Influenza A
pyu05165  Human papillomavirus infection
pyu05166  Human T-cell leukemia virus 1 infection
pyu05167  Kaposi sarcoma-associated herpesvirus infection
pyu05169  Epstein-Barr virus infection
pyu05200  Pathways in cancer
pyu05203  Viral carcinogenesis
pyu05212  Pancreatic cancer
pyu05214  Glioma
pyu05218  Melanoma
pyu05219  Bladder cancer
pyu05220  Chronic myeloid leukemia
pyu05222  Small cell lung cancer
pyu05223  Non-small cell lung cancer
pyu05224  Breast cancer
pyu05225  Hepatocellular carcinoma
Brite
KEGG Orthology (KO) [BR:pyu00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    121040857 (CDK4)
 09140 Cellular Processes
  09143 Cell growth and death
   04110 Cell cycle
    121040857 (CDK4)
   04115 p53 signaling pathway
    121040857 (CDK4)
   04218 Cellular senescence
    121040857 (CDK4)
  09144 Cellular community - eukaryotes
   04530 Tight junction
    121040857 (CDK4)
 09150 Organismal Systems
  09151 Immune system
   04660 T cell receptor signaling pathway
    121040857 (CDK4)
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    121040857 (CDK4)
   05203 Viral carcinogenesis
    121040857 (CDK4)
  09162 Cancer: specific types
   05212 Pancreatic cancer
    121040857 (CDK4)
   05225 Hepatocellular carcinoma
    121040857 (CDK4)
   05214 Glioma
    121040857 (CDK4)
   05220 Chronic myeloid leukemia
    121040857 (CDK4)
   05218 Melanoma
    121040857 (CDK4)
   05219 Bladder cancer
    121040857 (CDK4)
   05224 Breast cancer
    121040857 (CDK4)
   05222 Small cell lung cancer
    121040857 (CDK4)
   05223 Non-small cell lung cancer
    121040857 (CDK4)
  09172 Infectious disease: viral
   05166 Human T-cell leukemia virus 1 infection
    121040857 (CDK4)
   05160 Hepatitis C
    121040857 (CDK4)
   05164 Influenza A
    121040857 (CDK4)
   05162 Measles
    121040857 (CDK4)
   05163 Human cytomegalovirus infection
    121040857 (CDK4)
   05167 Kaposi sarcoma-associated herpesvirus infection
    121040857 (CDK4)
   05169 Epstein-Barr virus infection
    121040857 (CDK4)
   05165 Human papillomavirus infection
    121040857 (CDK4)
  09167 Endocrine and metabolic disease
   04933 AGE-RAGE signaling pathway in diabetic complications
    121040857 (CDK4)
   04934 Cushing syndrome
    121040857 (CDK4)
  09176 Drug resistance: antineoplastic
   01522 Endocrine resistance
    121040857 (CDK4)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases [BR:pyu01001]
    121040857 (CDK4)
Enzymes [BR:pyu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.11  Protein-serine/threonine kinases
    2.7.11.22  cyclin-dependent kinase
     121040857 (CDK4)
Protein kinases [BR:pyu01001]
 Serine/threonine kinases: CMGC group
  CDK family
   121040857 (CDK4)
SSDB
Motif
Pfam: Pkinase PK_Tyr_Ser-Thr APH Kdo ABC1 Haspin_kinase Kinase-like
Other DBs
NCBI-GeneID: 121040857
NCBI-ProteinID: XP_040347510
LinkDB
Position
Unknown
AA seq 307 aa
MATPRYEPVAEIGVGAYGTVYKARDPHSGHFVALKSVRVPNGGGASGGLPISTVREVALL
RRLEAFEHPNVVRLMDVCATARTDRETKVTLVFEHVDQDLRTYLDKAPPPGLPVETIKDL
MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVSRKVV
TLWYRAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPED
DWPRDVSLPRGAFSPRGPRPVQSVVPELEESGAQLLLEMLTFNPHKRISAFRALQHSYLQ
KAEGNPE
NT seq 924 nt   +upstreamnt  +downstreamnt
atggccactcctcgatatgagccagtggccgagattggtgttggtgcttatggaaccgtg
tacaaggcccgtgatccccacagtggccactttgtggccctcaagagtgtgagagtccct
aacggaggaggtgctagcgggggccttcccatcagcacagttcgtgaggtggccttactg
aggcggctggaggcttttgaacatcctaatgttgtccggctgatggatgtctgtgccact
gcccgaactgaccgagagaccaaagtgaccctggtgtttgagcatgtggaccaagaccta
aggacatatctggacaaggcacccccaccaggcttgccagtggagactatcaaggatctg
atgcgccagtttctaagaggcctagatttcctccatgccaactgcattgttcatcgagat
ctgaagccagagaacattctggtgacaagtggtgggacagtcaagctggctgactttggc
ctggccagaatctacagctatcagatggcacttacacctgtggtcagtagaaaggttgtt
acactctggtaccgtgctccggaagttcttctgcagtctacgtacgcaacacctgtggac
atgtggagcgttggctgtatcttcgcagagatgtttcgtcgcaagcctctcttctgtgga
aactctgaagctgaccagttaggcaaaatctttgacctgatcgggctgcccccagaggat
gactggccccgagatgtgtctctgccccgaggagccttttcccccagaggaccccgtcca
gtgcagtcagtggtacctgagttggaggagtctggagcacagctgctgctggagatgctg
acttttaacccacacaagcgaatctctgccttccgagccctgcagcactcttatctacaa
aaggcagaaggtaacccagagtga

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