Puma yagouaroundi (jaguarundi): 121043038
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Entry
121043038 CDS
T07555
Symbol
PTK2
Name
(RefSeq) focal adhesion kinase 1 isoform X1
KO
K05725
focal adhesion kinase 1 [EC:
2.7.10.2
]
Organism
pyu
Puma yagouaroundi (jaguarundi)
Pathway
pyu01522
Endocrine resistance
pyu04012
ErbB signaling pathway
pyu04062
Chemokine signaling pathway
pyu04148
Efferocytosis
pyu04151
PI3K-Akt signaling pathway
pyu04360
Axon guidance
pyu04370
VEGF signaling pathway
pyu04510
Focal adhesion
pyu04670
Leukocyte transendothelial migration
pyu04810
Regulation of actin cytoskeleton
pyu04935
Growth hormone synthesis, secretion and action
pyu05100
Bacterial invasion of epithelial cells
pyu05135
Yersinia infection
pyu05146
Amoebiasis
pyu05163
Human cytomegalovirus infection
pyu05165
Human papillomavirus infection
pyu05170
Human immunodeficiency virus 1 infection
pyu05200
Pathways in cancer
pyu05202
Transcriptional misregulation in cancer
pyu05205
Proteoglycans in cancer
pyu05208
Chemical carcinogenesis - reactive oxygen species
pyu05222
Small cell lung cancer
pyu05417
Lipid and atherosclerosis
pyu05418
Fluid shear stress and atherosclerosis
Brite
KEGG Orthology (KO) [BR:
pyu00001
]
09130 Environmental Information Processing
09132 Signal transduction
04012 ErbB signaling pathway
121043038 (PTK2)
04370 VEGF signaling pathway
121043038 (PTK2)
04151 PI3K-Akt signaling pathway
121043038 (PTK2)
09140 Cellular Processes
09141 Transport and catabolism
04148 Efferocytosis
121043038 (PTK2)
09144 Cellular community - eukaryotes
04510 Focal adhesion
121043038 (PTK2)
09142 Cell motility
04810 Regulation of actin cytoskeleton
121043038 (PTK2)
09150 Organismal Systems
09151 Immune system
04670 Leukocyte transendothelial migration
121043038 (PTK2)
04062 Chemokine signaling pathway
121043038 (PTK2)
09152 Endocrine system
04935 Growth hormone synthesis, secretion and action
121043038 (PTK2)
09158 Development and regeneration
04360 Axon guidance
121043038 (PTK2)
09160 Human Diseases
09161 Cancer: overview
05200 Pathways in cancer
121043038 (PTK2)
05202 Transcriptional misregulation in cancer
121043038 (PTK2)
05205 Proteoglycans in cancer
121043038 (PTK2)
05208 Chemical carcinogenesis - reactive oxygen species
121043038 (PTK2)
09162 Cancer: specific types
05222 Small cell lung cancer
121043038 (PTK2)
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
121043038 (PTK2)
05163 Human cytomegalovirus infection
121043038 (PTK2)
05165 Human papillomavirus infection
121043038 (PTK2)
09171 Infectious disease: bacterial
05135 Yersinia infection
121043038 (PTK2)
05100 Bacterial invasion of epithelial cells
121043038 (PTK2)
09174 Infectious disease: parasitic
05146 Amoebiasis
121043038 (PTK2)
09166 Cardiovascular disease
05417 Lipid and atherosclerosis
121043038 (PTK2)
05418 Fluid shear stress and atherosclerosis
121043038 (PTK2)
09176 Drug resistance: antineoplastic
01522 Endocrine resistance
121043038 (PTK2)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
pyu01001
]
121043038 (PTK2)
01009 Protein phosphatases and associated proteins [BR:
pyu01009
]
121043038 (PTK2)
Enzymes [BR:
pyu01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
121043038 (PTK2)
Protein kinases [BR:
pyu01001
]
Non-receptor tyrosine kinases
FAK family
121043038 (PTK2)
Protein phosphatases and associated proteins [BR:
pyu01009
]
Protein serine/threonine phosphatases
Phosphoprotein phosphatases (PPPs)
Protein phosphatase-1
PP1-interacting proteins (PIPs)
121043038 (PTK2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Focal_AT
Pkinase
FERM_C_FAK1
FERM_N_2
FERM_M
Kinase-like
Haspin_kinase
FERM_F2
GIT1_C
ABC1
Motif
Other DBs
NCBI-GeneID:
121043038
NCBI-ProteinID:
XP_040350440
LinkDB
All DBs
Position
Unknown
AA seq
1142 aa
AA seq
DB search
MTARGSIAVLLECLTFARNKTIKDYDRYIAPSKIMAAAYLDPNLNHTPNSSTKTHLGTGV
ERSPGAMERVLKVFHYFENSSEPATWASIIRHGDATDVRGIIQKIVDSHKVKHVACYGFR
LSHLRSEEVHWLHLDMGVSNVREKYELAHPPEEWKYELRIRYLPKGFLNQFTEDKPTLNF
FYQQVKSDYMSEIADRVDQDIALKLGCLEIRRSYWEMRGNALEKKSNYEVLEKDVGLKRF
FPRSLLDSVKAKTLRKLIQQTFRQFANLNREESILKFFEILSPVYRFDKECFKCALGSSW
IISVELAIGPEEGISYLTDKGCSPTHLADFNQVQTIQYSNSEDKDRKGTLQLKIAGAPEP
LTVTAPSLTIAENMADLIDGYCRLVNGATQSFIIRPQKEGERALPSIPKLANSEKQGVRT
HAVSVSGIYPDATHSAARALTWASRSVSPLGALATSPSPLTLLSPCPTSLLLETDDYAEI
IDEEDTYTMPSKSYGIDEARDYEIQRERIELGRCIGEGQFGDVHQGVYMSPENPALAVAI
KTCKNCTSDSVREKFLQEALTMRQFDHPHIVKLVGVITENPVWIIMELCTLGELRSFLQV
RKYSLDLASLILYAYQLSTALAYLESKRFVHRDIAARNVLVSSNDCVKLGDFGLSRYMED
STYYKASKGKLPIKWMAPESINFRRFTSASDVWMFGVCMWEILMHGVKPFQGVKNNDVIG
RIENGERLPMPPNCPPTLYSLMTKCWAYDPSRRPRFTELKAQLSTILEEEKVQQEERMRM
ESRRQVTVSWDSGGSDEAPPKPSRPGYPSPRSSEGFYPSPQHMVQTNHYQVSGYPGSHGV
TATAGSIYPGQASLLEQTDSWNHRPQEISMWQPNVEDSAALDLRGMGQVLPTQLVEERLI
RQQQEMEEDQRWLEKEERFLVILKPDVRLSRGSIDREDGSLQGPTGNQHIYQPVGKPDPA
APPKKPPRPGAPGHLGSLASLSSPGDSYNEGVKLQPQEISPPPTANLDRSNDRVYENVTG
LVKAVIEMSSKIQPAPPEEYVPMVKEVGLALRTLLATVDETLPVLPASTHREIEMAQKLL
NSDLGELINKMKLAQRCAMTSLQQDHKKQMLTAAHALAVDAKNLLDVIDQARLRALGHAR
PR
NT seq
3429 nt
NT seq
+upstream
nt +downstream
nt
atgacagccagaggtagcattgcagtcctactagaatgcctcacatttgcacgaaacaag
acaataaaagattatgacagatacatagcaccaagcaaaataatggcagctgcttacctt
gacccaaacttgaatcacaccccaaattcgagtaccaagacccatctgggtaccggagtg
gaacgttcccccggggcaatggagcgagtgttgaaggtctttcattattttgagaacagc
agcgagccagccacttgggccagtattatcaggcacggagatgctactgatgtcaggggc
atcattcagaagatagtggacagtcacaaagtaaagcacgtggcctgctatggatttcgt
ctcagtcacctgcggtcagaggaggttcactggctccatttggatatgggtgtctccaat
gtgagggagaagtatgaacttgcacacccaccagaggagtggaaatatgaattgagaatt
cgttatttgccaaaaggatttctaaaccagtttactgaagacaagccaactctgaatttc
ttctatcaacaggtgaaaagtgactacatgtcggagatagctgaccgggtggaccaggac
atcgctttgaagctgggctgcctagaaatacggcgctcgtattgggagatgcgaggcaac
gcgctagagaagaagtccaactatgaggtgttagaaaaagatgttggtttgaagcgattt
tttcctaggagtttactggattctgtcaaggccaaaacactaagaaaactgatccagcag
acgtttagacagttcgccaacctgaacagagaagagagcattctgaaattctttgagatc
ctctccccagtgtaccgatttgataaagagtgcttcaagtgtgccctcggttcaagctgg
attatttcagtggaactggcgatcggcccagaagaaggaatcagttacctcacggacaag
ggctgcagccccacgcatctggccgacttcaatcaagtgcagaccattcagtactccaac
agcgaagacaaggaccggaaaggaacactgcagctgaaaatcgcgggcgcccccgagcct
ctgacagtgacagcaccgtccctgaccatcgccgagaatatggccgacctgatagatggg
tactgccggctggtgaacggagccacgcagtcctttatcatcaggccccagaaagaaggt
gaacgggctttgccatcaataccaaagctggccaacagcgagaagcaaggcgtgcggaca
cacgcggtctccgtgtcaggcatctaccctgacgccactcacagtgcagccagagccctg
acgtgggcttctaggtctgtgtcaccactgggagcactggccacctctccctcacctctc
actcttttgtcaccctgcccaacctcattgctcctcgaaaccgacgactatgctgagatt
atagacgaagaagatacctacacgatgccctcaaaaagctatggaatagacgaagccagg
gactacgagattcaaagagaaagaatcgagcttggacggtgcatcggggaaggccagttt
ggggacgtccaccaaggcgtctacatgagtccagagaatccggctttggcggtcgcaatt
aaaacatgtaaaaactgtacctcggacagcgtgcgagagaaattccttcaagaagcctta
acgatgcgccagtttgaccacccccacatcgtgaagctggtcggtgtcatcacggagaac
cccgtctggataatcatggagctgtgcacgcttggagagctgaggtcgtttctgcaagtg
aggaagtacagtttggatctcgcgtctttgatcctgtatgcctatcagcttagcacagct
ctggcgtatctggagagcaaaagattcgtgcacagggacattgctgctcggaatgttctg
gtgtcctcaaacgattgcgtaaaattaggagactttggattatcccggtatatggaagac
agtacttactacaaagcttccaaaggaaagttgcctattaaatggatggctccagagtcc
atcaactttcgacgttttacctcagccagtgacgtgtggatgtttggtgtgtgtatgtgg
gagatactgatgcatggcgtgaagccgtttcaaggagtgaagaacaatgatgtgatcggt
cgcatcgagaacggggagagattaccgatgcctccaaattgccctcccaccctctacagc
cttatgacgaaatgctgggcctatgaccccagcaggcggccccggttcactgagctcaaa
gctcagctcagcaccatcctggaggaggagaaggttcagcaagaagaacgaatgaggatg
gaatcccgaagacaggtcacagtgtcctgggactccggagggtccgacgaagcgccaccc
aagcccagcagacctggttaccccagtccacggtccagcgaaggattttatcccagtccc
cagcacatggtacagaccaatcattaccaggtgtctggctatcctggctcacatggggtc
acagccacggctggcagcatctacccgggtcaggcatctcttttggaacagacggactca
tggaaccacagaccacaggagatatcgatgtggcagcccaacgtggaggactctgcggcc
ctggacctgcgcgggatggggcaggtgctgcccacccagctggtggaagagcggctgatc
cggcagcagcaggaaatggaggaggaccagcgctggctcgagaaagaggagagattcctg
gtcatcctgaaacctgacgtgcggctctctcgaggcagcatcgacagggaggacgggagt
cttcagggcccgacgggaaaccaacacatctatcagcctgtgggtaaaccagatcccgca
gctccgccaaagaaaccgccgcggcctggagcccccggtcacctgggcagcctcgccagc
ctcagcagccccggggacagttacaacgagggcgtcaagcttcagccccaggaaatcagc
cccccgcccactgccaacctggaccggtccaacgacagggtgtacgagaacgtgacgggc
ctggtgaaggctgtcatcgaaatgtccagcaagatccagccagcccccccggaggagtat
gttcccatggtgaaggaagtcggcctggccctgcggacattactggccaccgtggacgag
acccttccggtcctgccagccagcactcaccgagagatcgagatggcccagaagctgttg
aactccgacctgggcgagctcatcaacaagatgaagctggcccagcggtgcgccatgacc
agcctacagcaggaccacaagaagcagatgctgaccgccgcccacgccctggccgtggac
gccaagaacttactcgacgtcatcgaccaggccagactgagggcactcggacacgcgagg
ccgcgctga
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