Rousettus aegyptiacus (Egyptian rousette): 107511114
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Entry
107511114 CDS
T06036
Symbol
IRS2
Name
(RefSeq) insulin receptor substrate 2 isoform X1
KO
K07187
insulin receptor substrate 2
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04022
cGMP-PKG signaling pathway
ray04068
FoxO signaling pathway
ray04081
Hormone signaling
ray04140
Autophagy - animal
ray04152
AMPK signaling pathway
ray04211
Longevity regulating pathway
ray04213
Longevity regulating pathway - multiple species
ray04910
Insulin signaling pathway
ray04920
Adipocytokine signaling pathway
ray04923
Regulation of lipolysis in adipocytes
ray04930
Type II diabetes mellitus
ray04931
Insulin resistance
ray04932
Non-alcoholic fatty liver disease
ray04935
Growth hormone synthesis, secretion and action
ray05010
Alzheimer disease
ray05206
MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09130 Environmental Information Processing
09132 Signal transduction
04068 FoxO signaling pathway
107511114 (IRS2)
04022 cGMP-PKG signaling pathway
107511114 (IRS2)
04152 AMPK signaling pathway
107511114 (IRS2)
09133 Signaling molecules and interaction
04081 Hormone signaling
107511114 (IRS2)
09140 Cellular Processes
09141 Transport and catabolism
04140 Autophagy - animal
107511114 (IRS2)
09150 Organismal Systems
09152 Endocrine system
04910 Insulin signaling pathway
107511114 (IRS2)
04923 Regulation of lipolysis in adipocytes
107511114 (IRS2)
04920 Adipocytokine signaling pathway
107511114 (IRS2)
04935 Growth hormone synthesis, secretion and action
107511114 (IRS2)
09149 Aging
04211 Longevity regulating pathway
107511114 (IRS2)
04213 Longevity regulating pathway - multiple species
107511114 (IRS2)
09160 Human Diseases
09161 Cancer: overview
05206 MicroRNAs in cancer
107511114 (IRS2)
09164 Neurodegenerative disease
05010 Alzheimer disease
107511114 (IRS2)
09167 Endocrine and metabolic disease
04930 Type II diabetes mellitus
107511114 (IRS2)
04932 Non-alcoholic fatty liver disease
107511114 (IRS2)
04931 Insulin resistance
107511114 (IRS2)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
IRS
PH
PH_11
MEKK4_N
Mcp5_PH
Motif
Other DBs
NCBI-GeneID:
107511114
NCBI-ProteinID:
XP_016000743
LinkDB
All DBs
Position
Unknown
AA seq
1407 aa
AA seq
DB search
MASPPLQGPPVLAGGDGPNLNNNNNNNNHSVRKCGYLRKQKHGHKRFFVLRGPGAVGDEA
TASAGGGPAPQPPRLEYYESEKKWRSKAGAPKRVISLDCCLNINKRADAKHKYLIALYTK
DEYFAVAAENEQEQEGWYRALTDLVSEGRTVAGDALSSAASAGSCSASLPGALGGSAGAD
DSYGLVAPATAAYREVWQVNLKPKGLGQSKNLTGVYRLCLSARTIGFVKLNCEQPSVTLQ
LMNIRRCGHSDSFFFIEVGRSAVTGPGELWMQADDSVVAQNIHETILEAMKALKELFEFR
PRSKSQSSGSSATHPISVPGARRHHHLVNLPPSQTGLVRRSRTDSLAATPPAAKCSSCRV
RTASEGDGGAAAGSGAAGGRPVSVAGSPLSPGPVRAPLSRSHTLSGGCGSRASKVTLTPA
GGALQHSRSMSMPVAHSPPAATSPGSLSSSSGHGSGSYPPPPGPHPHLQHPLQHHAGQRP
SSGSASASGSPSDPGFMSLDEYGSSPGDLRAFCSHRSNTPESIAETPPARDGSGSELYGY
MTMDRPLSHCGRPYRRISGDGAQDLDRGLRKRTYSLTTPARQRPVPQPSSASLDEYTLMR
ATFSGSSGRLCPSCPASSPKVAYHPYPEDYGDIEIGSHRSSSSNLGTDDGYMPMTPGVAL
MGGGSGSCKSDDYMPMSPTSVSAPKQILQPRAAAAALPPTGAAVPAPASVTSSRAFPVNG
ASYKASSPAESSPEDSGYMRMWCGSKLTMENTDSKLLPNGDYLNMSPSDAGASETPPDFF
SAALHGGGEMLRGVPGYCYSSLPRSYKAPYTCSGDNDQYVLMSSPVGRILEEERPEPQAS
AGTTQSASVFVAGVGGGSHTQPPHSVVPSPGRLSGSGCGRPEGFLNQRCRAVRPTRLSLE
GLQTLPRMHEYPLPPEPKSPGEYINIDFGETGTRLSPPAPPLLASAASSSSLLSASSPAS
SLGSGTPGTSSDSRQRSPLSDYMNLDFSSPKSPKPSTQSGDPVGSLDALLSPEASSQYPP
LPPRPAAPSSLQPQPPPPPPPGELYRLPPASTSQGPSAASSSSLETGDNGDYTEMAFGVA
ATPPQPIVAPPKPEGARVTSPTSGLKRLSLMDQVSGVEAFLQAGQPPDPHRGAKVIRADP
QGGRRRHSSETFSSTTTVTPVSPSFAHNPKRHNSASVENVSLRKSSEGGGSGILGGGDEP
SSSPHQLQPPLPQQARPWTPNQPGGLVGCPGNSGSPMRRETSAGFQNGLNYIAIDVRDEP
GLSSPPQQHLHSQQHPHSQSGDKNTWGRTRSLGGLISAVGANSTGGVCGGPSPGTLPSAN
TYASIDFLSHHLKEATIVKDTHDLPRKAPLSCAEEASWPSAAPSTHNASCSENLPLLDPL
PSATVAAVVGGGQAHLAGQLCVSNPSG
NT seq
4224 nt
NT seq
+upstream
nt +downstream
nt
atggcgagcccgccgctgcaggggccccccgtgttggcgggcggcgacggccccaacctc
aacaacaacaacaacaacaacaaccacagcgtgcgcaagtgcggctacctgcgcaagcag
aagcacggccacaagcgcttcttcgtgctgcgcggccccggcgcggttggcgacgaggca
actgcctcagcgggcgggggtccggcgccgcagccgccgcggctcgagtactacgagagc
gagaagaagtggcggagcaaggcgggcgccccgaagcgggtcatctcgcttgactgctgc
ttgaacatcaacaagcgcgccgacgccaagcacaagtacctgatcgccctctacaccaag
gacgagtacttcgccgtggcggccgagaacgagcaggagcaggagggctggtaccgcgcg
ctcaccgacctggtcagcgagggccgcacggttgccggcgacgcgctctcctccgccgcc
tccgctgggtcctgcagcgcctctttgcctggcgccctgggcggctcggccggcgctgat
gacagctacgggctggtggcgcccgccacagccgcctatcgcgaggtgtggcaggtgaac
ctgaagcccaagggcctgggtcagagcaaaaacctgacgggcgtgtaccgtctttgcctg
tcggcgcgcaccatcggcttcgtgaagctcaactgcgaacagccgtcggtgacgctgcaa
ctcatgaacattcgccgctgcggccactcggacagtttcttcttcatcgaggttggccgc
tcagctgtcaccggccccggcgagctgtggatgcaggccgacgactcggtggtggcacag
aacatccatgagaccatcctagaggccatgaaggcgctcaaggagctctttgagttccgg
ccgcgcagcaagagccagtcgtcgggatcatcagccacgcaccccattagcgtccctggc
gcgcgccgtcaccaccacctggtcaacttgccccccagccaaacgggcttggtgcggcgc
tcgcgcaccgacagcctggctgccaccccgccagccgccaaatgcagctcctgccgggtg
cgcacggccagcgagggcgacggcggcgcggcggcggggagtggggcggcgggcggcagg
cccgtgtcggtggcggggagccccctgagcccggggcctgtgcgcgcgccgcttagtcgc
tcgcacaccctgagcggcggctgcggcagccgcgcgagcaaggtaacgctgacgccagca
gggggcgccctgcagcacagccgctcgatgtccatgcccgtggctcactcgccccctgcc
gccaccagccccggaagcctgtcttccagcagtgggcacggctcaggctcctacccgccg
cctccgggcccgcacccacacctacagcacccgttgcagcaccacgcgggccagcgtcct
tccagcggcagcgcttcagcctccggctcccccagcgatcccggctttatgtctctggat
gagtacggctccagtcctggggacctgagagccttctgtagccacaggagcaacactcct
gagtccatcgccgagacaccccctgccagggatggcagcgggagtgagctgtatggctac
atgaccatggacaggcccctgagccactgtggccgcccctaccgtcgtatttcaggagac
ggagctcaggacttggacagagggctaaggaagaggacttactccctgaccacacctgcc
cggcagcgaccggtgccccagccctcctctgcgtccctggatgaatacaccctgatgcgg
gccaccttctctggcagctcgggccgcctctgcccgtcctgccctgcgtcttctcccaaa
gtggcctaccacccctatcccgaagactacggcgacattgagattgggtcgcataggagc
tccagcagtaacctgggcacggacgatggctacatgcccatgacccctggcgtggccctc
atgggtggtggcagtggcagctgcaagagtgacgactacatgcccatgagtcccaccagc
gtgtctgccccaaagcagatcttgcagccacgggctgctgcagcagccttgccccccacc
ggagctgcagtgccagcgccagcctctgtgaccagcagcagggcctttccagtgaacggg
gccagttacaaggccagctccccggccgagagctcgcccgaagacagtggatacatgcgc
atgtggtgtggttccaagttgaccatggagaatacagacagcaagctgcttcccaatggg
gactacctcaacatgtcccccagcgatgcaggcgcctcggaaaccccgccagacttcttc
tcagcagccttgcatggcggtggggagatgctcaggggcgttcctggctactgttacagt
tctttgccccgctcctataaggctccttacacctgtagtggggacaatgaccagtacgta
ctcatgagctccccggtggggcgcatcctggaagaggagaggccggagccgcaggccagt
gcagggaccacgcagtcggctagcgtcttcgtggctggggtgggtgggggcagtcacacc
cagcctcctcactccgtagtgccttcgcctgggaggctgagtggcagcggctgtggccgc
ccagagggtttcctgaaccaacgctgtcgggcagtacgacccacgcgcctgtccctggag
gggcttcagactctacccaggatgcacgagtatcctctgccgccggagcccaagagcccg
ggcgaatacatcaacattgactttggcgaaaccggaacgcgcttgtcaccgcctgcccct
ccactgctggcttccgctgcctcgtcctcctcgctgttgtctgccagcagcccagcctca
tccctgggctctggtactccgggcacaagcagcgacagccggcagcgctctccgctctcc
gactacatgaacctcgacttcagctcacccaagtcacccaaaccgagtacccagagcggg
gacccggtggggtccttggatgccctcctgtctcctgaggcctcctcccagtacccccca
ctgcctcctcgccctgctgccccctcctccttgcagcctcagccgccacccccacctccc
ccaggggagctgtaccgcctgcctccagcatccacatcccagggccccagcgctgcctcc
tcttcatccttggagactggggacaatggtgactacaccgagatggcctttggcgtagct
gccaccccgccacaacccatcgtggcccccccgaagccggaaggtgcccgcgtgaccagc
cccacgtccggcctgaagaggctgagtctcatggatcaggtgtctggagtggaagccttt
ttgcaggctggccagcccccagacccacaccggggggccaaggtcatccgggcagacccg
caggggggccgccgccgccacagctccgagaccttctcctcgaccaccactgtgaccccc
gtgtccccatccttcgcccacaacccgaagcgccacaactcggcctccgtggaaaacgtc
tctctcaggaaaagcagcgaaggaggtggcagtggcatccttggtgggggtgatgaacct
tcctcttcccctcaccagttgcaaccacccctcccccagcaggcacggccatggacaccg
aatcagcctgggggtctggttggctgccctgggaacagtggctctcctatgcgcagggag
acctctgctggcttccagaatggcctcaactacatcgccatcgatgtgagagatgagcca
gggctgtcgtctcccccacaacaacacctgcattcgcagcaacatccacattcgcagtca
ggcgacaagaacacttggggccggacccgtagcctcgggggtctcatcagcgctgtgggg
gccaacagcaccggtggagtgtgtggggggcccagccctggcaccctaccctcagccaac
acctatgccagcattgacttcttgtcccatcacctgaaggaggccaccattgtgaaagac
acccatgatctacccaggaaagcccccctctcctgtgcagaggaggcctcctggccatca
gcagccccctctacccataatgcctcctgctctgagaacctgcctctgctggaccccctg
ccctccgccacagtggctgctgttgtcgggggagggcaggcccacttggctgggcagctc
tgtgtttccaacccatcaggctga
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