Rousettus aegyptiacus (Egyptian rousette): 107519483
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Entry
107519483 CDS
T06036
Symbol
ITCH
Name
(RefSeq) E3 ubiquitin-protein ligase Itchy homolog isoform X1
KO
K05632
E3 ubiquitin-protein ligase Itchy [EC:
2.3.2.26
]
Organism
ray
Rousettus aegyptiacus (Egyptian rousette)
Pathway
ray04120
Ubiquitin mediated proteolysis
ray04144
Endocytosis
ray04330
Notch signaling pathway
ray04668
TNF signaling pathway
ray04932
Non-alcoholic fatty liver disease
Brite
KEGG Orthology (KO) [BR:
ray00001
]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
107519483 (ITCH)
09130 Environmental Information Processing
09132 Signal transduction
04330 Notch signaling pathway
107519483 (ITCH)
04668 TNF signaling pathway
107519483 (ITCH)
09140 Cellular Processes
09141 Transport and catabolism
04144 Endocytosis
107519483 (ITCH)
09160 Human Diseases
09167 Endocrine and metabolic disease
04932 Non-alcoholic fatty liver disease
107519483 (ITCH)
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04131 Membrane trafficking [BR:
ray04131
]
107519483 (ITCH)
04121 Ubiquitin system [BR:
ray04121
]
107519483 (ITCH)
Enzymes [BR:
ray01000
]
2. Transferases
2.3 Acyltransferases
2.3.2 Aminoacyltransferases
2.3.2.26 HECT-type E3 ubiquitin transferase
107519483 (ITCH)
Membrane trafficking [BR:
ray04131
]
Endocytosis
Clathrin-mediated endocytosis
Ubiquitin E3 ligases
107519483 (ITCH)
Ubiquitin system [BR:
ray04121
]
Ubiquitin ligases (E3)
HECT type E3
107519483 (ITCH)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
HECT
WW
C2
Motif
Other DBs
NCBI-GeneID:
107519483
NCBI-ProteinID:
XP_016017706
LinkDB
All DBs
Position
Unknown
AA seq
862 aa
AA seq
DB search
MSDSGLELDSMGSLTMKSQLQITVISAKLKENKKNWFGPSPYVEVAVDGQSKKTEKCNNT
NSPKWKQPLTVIVTPVSKLHFRVWSHQTLKSDVLLGTAALDIYETLKSNNMKLEEVVVTL
QLAGDKEPTETMGDLSVCLDGLQLESEVVTNGETTCSESASQNDDGSRPKDETRVNTNGS
DDAEDAGSGENKRVNGNNSPSLSNGGFKPSRPPRPSRPPPPTPRRPASVNGSPSATSESD
GSSTGSLPPTNTNSNTSEGATSGLIIPLTISGGSGPRPLNPVPQAPLPPGWEQRMDQHGR
VYYVDHIEKRTTWDRPEPLPPGWERRVDNMGRIYYVDHFTRTTTWQRPTLESVRNYEQWQ
LQRSQLQGAMQQFNQRFIYGNQDLFATSQNKEFDPLGPLPPGWEKRTDSNGRVYFVNHNT
RITQWEDPRSQGQLNEKPLPEGWEMRFTVDGIPYFVDHNRRTTTYIDPRTGKSALDNGPQ
IAYVRDFKAKFQYFRFWCQQLAMPQHIKITVTRKTLFEDSFQQIMSFSPQDLRRRLWVIF
PGEEGLDYGGVAREWFFLLSHEVLNPMYCLFEYAGKDNYCLQINPASYINPDHLKYFRFI
GRFIAMALFHGKFIDTGFSLPFYKRILNKPVGLKDLESIDPEFYNSLIWVKENNIEECGL
EMYFSVDKEILGEIKSHDLKPNGGNILVTEENKEEYIRMVAEWRLSRGVEEQTQAFFEGF
NEILPQQYLQYFDAKELEVLLCGMQEIDLNDWQRHAIYRHYTRTSKQIMWFWQFVKEIDN
EKRMRLLQFVTGTCRLPVGGFADLMGSNGPQKFCIEKVGKENWLPRSHTCFNRLDLPPYK
SYEQLKEKLLFAIEETEGFGQE
NT seq
2589 nt
NT seq
+upstream
nt +downstream
nt
atgtctgacagtggattagagcttgattcaatgggtagcctgaccatgaaatcacaactt
caaatcactgtcatttcagcaaaacttaaagaaaataaaaagaattggtttgggccaagt
ccttatgtggaagtcgcagtagatggacagtcaaagaagacagaaaaatgcaacaatacg
aacagtcccaaatggaagcaaccccttacagttatcgtcactcctgtaagtaaattacat
tttcgtgtgtggagtcaccagacactgaaatctgatgttttgttgggaactgctgcatta
gatatctatgaaacattaaagtcaaacaatatgaaacttgaggaagtagttgtgacttta
cagcttgcaggtgacaaagagccaacagaaacaatgggagacttgtcagtttgtcttgat
gggctgcagttagagtctgaagttgttaccaatggtgaaacgacatgttcagaaagtgct
tcacagaatgatgatggctccagacctaaggatgaaacaagagtgaacacaaatggatca
gatgacgctgaggatgcagggtctggtgaaaataagagagtcaatgggaataattctcca
tcactctcaaatggcggttttaaaccttctaggcctccaagaccttcacgaccacctcca
cctaccccacgtagaccagcatctgtcaatggttcaccttctgccacttctgaaagtgat
ggatctagtacaggttctctgccaccaacaaatacaaattcaaatacatctgaaggagct
acgtctggattaataattcctcttactatatctggaggctcaggccctaggccattaaat
cctgtacctcaagctcccctaccacctggttgggagcagagaatggaccaacatgggcga
gtttactatgtagatcatattgaaaaaagaacaacgtgggatagaccagaacctctacct
cctggctgggaacggcgggttgacaacatgggacgtatttattatgttgaccatttcaca
agaacaacaacatggcagaggccaacattggaatctgtccggaactatgaacagtggcag
ctccaacgtagtcagcttcaaggagcaatgcagcagtttaatcagagattcatttatggg
aatcaagatttgtttgctacatcacaaaataaagaatttgatcccctgggtcccctgcca
cctggatgggagaagagaacggacagcaatggaagagtatattttgtcaaccacaacact
cgtattacacagtgggaggaccccagaagtcaaggtcagttaaatgaaaagcccttacct
gaaggctgggaaatgagattcacagtggatggaattccctattttgtggaccacaataga
agaaccaccacctatatagatccccgcactggaaaatctgccctagacaatggaccccag
atagcctacgtacgagacttcaaggcaaagtttcagtatttccggttctggtgtcagcaa
ctggccatgccacaacacataaagattacagtgacaaggaaaacattgtttgaggattcc
tttcagcagataatgagcttcagtccccaagatctccgaagacgtttgtgggtgattttt
ccaggagaagaaggtttagattatggaggtgtagcaagagaatggttctttcttttgtca
catgaggtgttgaacccaatgtattgcctgtttgaatatgcagggaaggataactactgc
ttgcagataaaccccgcttcttacatcaatccagatcacctgaaatattttcgatttatt
ggaaggtttattgccatggctctgttccatgggaaattcatagacacaggcttttctttg
ccattctataagcgtatcttgaacaaaccagttggactcaaggatttagaatctattgat
ccagaattttacaattctctcatctgggttaaagaaaacaatattgaggaatgtggatta
gaaatgtacttctctgttgataaagaaattttgggtgaaatcaagagtcatgatttgaaa
cccaatggtggcaatatccttgtaacagaagaaaataaagaagaatatatcagaatggta
gccgaatggaggttgtctcgaggtgttgaagaacagacacaagctttctttgagggcttt
aatgaaattcttccccagcagtatttgcagtactttgatgcaaaggaactagaggttctt
ttatgtggaatgcaagagattgatctgaatgattggcaaagacatgccatttaccgtcat
tacactaggacaagcaaacaaatcatgtggttttggcagtttgttaaagaaattgataat
gagaagagaatgagacttctacagtttgttactggaacctgccgattgccagttggagga
tttgctgacctcatggggagcaatggaccacagaaattctgtattgaaaaagttgggaaa
gaaaattggttacccagaagtcatacctgttttaaccgcctggacctgccaccctacaag
agctatgagcaactgaaggaaaagctgttatttgccattgaagaaacagaaggatttgga
caagagtga
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