Rhinopithecus bieti (black snub-nosed monkey): 108518588
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Entry
108518588 CDS
T04641
Symbol
LCK
Name
(RefSeq) tyrosine-protein kinase Lck isoform X1
KO
K05856
lymphocyte cell-specific protein tyrosine kinase [EC:
2.7.10.2
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb04064
NF-kappa B signaling pathway
rbb04380
Osteoclast differentiation
rbb04650
Natural killer cell mediated cytotoxicity
rbb04658
Th1 and Th2 cell differentiation
rbb04659
Th17 cell differentiation
rbb04660
T cell receptor signaling pathway
rbb05135
Yersinia infection
rbb05166
Human T-cell leukemia virus 1 infection
rbb05235
PD-L1 expression and PD-1 checkpoint pathway in cancer
rbb05340
Primary immunodeficiency
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09130 Environmental Information Processing
09132 Signal transduction
04064 NF-kappa B signaling pathway
108518588 (LCK)
09150 Organismal Systems
09151 Immune system
04650 Natural killer cell mediated cytotoxicity
108518588 (LCK)
04660 T cell receptor signaling pathway
108518588 (LCK)
04658 Th1 and Th2 cell differentiation
108518588 (LCK)
04659 Th17 cell differentiation
108518588 (LCK)
09158 Development and regeneration
04380 Osteoclast differentiation
108518588 (LCK)
09160 Human Diseases
09161 Cancer: overview
05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
108518588 (LCK)
09172 Infectious disease: viral
05166 Human T-cell leukemia virus 1 infection
108518588 (LCK)
09171 Infectious disease: bacterial
05135 Yersinia infection
108518588 (LCK)
09163 Immune disease
05340 Primary immunodeficiency
108518588 (LCK)
09180 Brite Hierarchies
09181 Protein families: metabolism
01001 Protein kinases [BR:
rbb01001
]
108518588 (LCK)
09182 Protein families: genetic information processing
03036 Chromosome and associated proteins [BR:
rbb03036
]
108518588 (LCK)
Enzymes [BR:
rbb01000
]
2. Transferases
2.7 Transferring phosphorus-containing groups
2.7.10 Protein-tyrosine kinases
2.7.10.2 non-specific protein-tyrosine kinase
108518588 (LCK)
Protein kinases [BR:
rbb01001
]
Non-receptor tyrosine kinases
SRC family
108518588 (LCK)
Chromosome and associated proteins [BR:
rbb03036
]
Eukaryotic type
Centrosome formation proteins
Kinases and associated factors
108518588 (LCK)
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
PK_Tyr_Ser-Thr
Pkinase
SH2
SH3_1
SH3_2
SH3_9
ABC1
Haspin_kinase
SH3_16
SH3_3
Motif
Other DBs
NCBI-GeneID:
108518588
NCBI-ProteinID:
XP_017712559
LinkDB
All DBs
Position
Unknown
AA seq
531 aa
AA seq
DB search
MGCGCSSHPEDDWMENIDVCENCHYPIVPLDGKGTLLIRNGSEVRDPLVIYEDSNPPASP
LQDNLVIALHSYEPSHDGDLGFEKGEQLRILEQSGEWWKAQSLTTGQEGFIPFNFVAKAN
SLEPEPWFFKNLSRKDAERQLLAPGNTHGSFLIRESESTAGERAVVSTRRGGAAGCARGG
AQGSFSLSVRDFDQNQGEVVKHYKIRNLDNGGFYISPRITFPGLRELVHHYTNASDGLCT
RLSRPCQTQKPQKPWWEDEWEVPRETLKLVERLGAGQFGEVWMGYYNGHTKVAVKSLKQG
SMSPDAFLAEANLMKQLQHQRLVRLYAVVTQEPIYIITEYMENGSLVDFLKTPSGIKLTI
NKLLDMAAQIAEGMAFIEERNYIHRDLRAANILVSDTLSCKIADFGLARLIEDNEYTARE
GAKFPIKWTAPEAINYGTFTIKSDVWSFGILLTEIVTHGRIPYPGMTNPEVIQNLERGYR
MPCPENCPEELYQLMRLCWKERPEDRPTFDYLRSVLEDFFTATEGQYQPQP
NT seq
1596 nt
NT seq
+upstream
nt +downstream
nt
atgggctgtggctgcagctcccacccggaagatgactggatggaaaacatcgatgtgtgt
gagaactgccattatcccatagttccactggatggcaagggcacgctgctcatccgaaat
ggctctgaggtgcgggacccactggtcatctatgaagactccaatccgccggcctcccca
ctgcaagacaacctggttatcgccctgcacagctatgagccctctcacgacggagacctg
ggctttgagaagggggaacagctccgcatcctggagcagagcggcgagtggtggaaggcg
cagtccctgaccacgggccaggaaggcttcatccccttcaattttgtggccaaggcgaac
agcctggagcccgaaccctggttcttcaagaacctgagccgcaaggacgcggagcggcag
ctcctggcgcccgggaacactcacggctccttcctcatccgggagagcgagagcaccgcg
ggtgagcgggcagtggtctcgacccggcgcgggggtgccgcggggtgtgcccgaggggga
gcgcagggatcgttttcactgtcggtccgggacttcgaccagaaccagggagaggtggtg
aaacattacaagatccgtaatctggacaacggtggcttctacatctccccccgaatcact
tttcccggcctgcgtgaactggtccaccattacaccaatgcttcagatgggctgtgcaca
cggctgagccgcccctgccagacccagaagccccagaagccgtggtgggaggatgagtgg
gaggttcccagggagacgctgaagttggtggagcggctgggggctggacagttcggggag
gtgtggatggggtactacaacgggcacacgaaggtagcagtgaagagcttgaagcagggt
agcatgtccccggacgccttcctggccgaggccaacctcatgaagcagctgcaacaccag
cggctggttcggctctacgctgtggtcacccaggagcccatctacatcatcactgaatac
atggagaatgggagtctagtggattttctcaagaccccttcaggcatcaagttgaccatc
aacaaactcctggacatggcagcccaaattgcagaaggcatggcattcattgaagagcgg
aactatattcatcgtgaccttcgggctgccaacattctggtgtctgacaccctgagctgc
aagattgcagactttggccttgcacgcctcattgaagacaacgagtacacagccagggag
ggagccaagtttcccattaagtggacagcgccagaagccattaactatgggacattcacc
atcaagtcggatgtgtggtcttttgggatcctgctgacggaaattgtcacccatggccgc
atcccttacccagggatgaccaacccggaggtgattcagaacctggagcgaggctaccgc
atgccgtgccctgaaaactgtccagaggagctgtaccaacttatgaggttgtgctggaag
gagcgcccggaggaccggcccacctttgactacctgcgcagtgtgctggaggacttcttc
acggccacagagggccagtaccagcctcagccttga
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