KEGG   Rhinopithecus bieti (black snub-nosed monkey): 108521035
Entry
108521035         CDS       T04641                                 
Name
(RefSeq) aldo-keto reductase family 1 member C4
  KO
K00037  3alpha-hydroxysteroid 3-dehydrogenase / chlordecone reductase [EC:1.1.1.50 1.1.1.357 1.1.1.225]
Organism
rbb  Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00120  Primary bile acid biosynthesis
rbb00140  Steroid hormone biosynthesis
rbb01100  Metabolic pathways
rbb05208  Chemical carcinogenesis - reactive oxygen species
Module
rbb_M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
rbb_M00977  C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:rbb00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    108521035
   00140 Steroid hormone biosynthesis
    108521035
 09160 Human Diseases
  09161 Cancer: overview
   05208 Chemical carcinogenesis - reactive oxygen species
    108521035
Enzymes [BR:rbb01000]
 1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.50  3alpha-hydroxysteroid 3-dehydrogenase (Si-specific)
     108521035
    1.1.1.225  chlordecone reductase
     108521035
    1.1.1.357  3alpha-hydroxysteroid 3-dehydrogenase
     108521035
SSDB
Motif
Pfam: Aldo_ket_red GT-D-like
Other DBs
NCBI-GeneID: 108521035
NCBI-ProteinID: XP_017716094
UniProt: A0A2K6KDX7
LinkDB
Position
Unknown
AA seq 323 aa
MDPKYQRVELNDGHFMPVLGFGSYAPPEVPRNRVVEVTKLAIEAGFRHIDSAYLYNNEEQ
VGLAIRSKIADGSVKREDIFYTSKLWCTFFRPQLVQPALESSLKKLQLDYVDLYIIHFPM
ALKPGETLLPTDENGKVIFDTVDLCAIWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKP
GLKYKPVCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDQNSPALLEDPV
LCALAKKHKRSPALIALRYQLQRGVVVLAKSYNEQRIRENVQVFEFQLTSEDMKVLDGLN
RNFRYVVMDFLVDHPDYPFLDEY
NT seq 972 nt   +upstreamnt  +downstreamnt
atggatcccaaatatcagcgtgtggagctaaatgatggtcacttcatgcccgtattggga
tttggctcctatgcacctccagaggttccgaggaacagagttgtggaggtcaccaaatta
gcaatagaagccggcttccgccatattgattctgcttatttatacaacaatgaggaacaa
gtaggactggccatccgaagcaagattgcagacggcagtgtgaagagagaagacatattc
tacacttcaaagctttggtgcactttctttcgaccacagttggtccaaccagccctggaa
agctcactaaaaaaacttcaattggactatgtggacctctatattattcatttcccaatg
gctctcaagccaggtgagacgctactaccaacagatgaaaatggaaaagtaatattcgac
acagtggatctctgtgccatatgggaggccatggagaagtgtaaggatgcaggattggcc
aagtccatcggggtgtcaaacttcaatcgcaggcagctggagatgatcctcaacaagcca
ggactcaagtacaagcccgtctgcaaccaggtggaatgtcatccttacctcaaccagagc
aaactgctggatttctgcaagtccaaagacattgtcctggttgcccacagtgctctggga
acccaacggcataaactatgggtggaccagaactccccagctcttttggaggacccagtt
ctttgcgccttagcaaagaaacacaaacgatccccagccctgattgccctgcgctaccag
ctgcagcgtggggttgtggtcctggccaagagctacaatgagcagcggatcagagaaaat
gtccaggtttttgaattccagttgacttcagaggatatgaaagttctagatggcctaaat
agaaattttcgatatgttgtcatggattttcttgtggaccaccctgattatccattttta
gatgaatattag

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