Rhinopithecus bieti (black snub-nosed monkey): 108528164
Help
Entry
108528164 CDS
T04641
Name
(RefSeq) 3 beta-hydroxysteroid dehydrogenase/Delta 5-->4-isomerase type 1-like
KO
K00070
3beta-hydroxy-Delta5-steroid dehydrogenase / steroid Delta-isomerase [EC:
1.1.1.145
5.3.3.1
]
Organism
rbb
Rhinopithecus bieti (black snub-nosed monkey)
Pathway
rbb00140
Steroid hormone biosynthesis
rbb01100
Metabolic pathways
rbb04913
Ovarian steroidogenesis
rbb04925
Aldosterone synthesis and secretion
rbb04927
Cortisol synthesis and secretion
rbb04934
Cushing syndrome
Module
rbb_M00107
Steroid hormone biosynthesis, cholesterol => pregnenolone => progesterone
rbb_M00110
C19/C18-Steroid hormone biosynthesis, pregnenolone => androstenedione => estrone
rbb_M00976
C19-Steroid hormone biosynthesis, pregnenolone => testosterone => dihydrotestosterone
rbb_M00977
C19-Steroid hormone biosynthesis (androgen backdoor pathway), pregnenolone => androsterone => dihydrotestosterone
Brite
KEGG Orthology (KO) [BR:
rbb00001
]
09100 Metabolism
09103 Lipid metabolism
00140 Steroid hormone biosynthesis
108528164
09150 Organismal Systems
09152 Endocrine system
04913 Ovarian steroidogenesis
108528164
04925 Aldosterone synthesis and secretion
108528164
04927 Cortisol synthesis and secretion
108528164
09160 Human Diseases
09167 Endocrine and metabolic disease
04934 Cushing syndrome
108528164
Enzymes [BR:
rbb01000
]
1. Oxidoreductases
1.1 Acting on the CH-OH group of donors
1.1.1 With NAD+ or NADP+ as acceptor
1.1.1.145 3beta-hydroxy-Delta5-steroid dehydrogenase
108528164
5. Isomerases
5.3 Intramolecular oxidoreductases
5.3.3 Transposing C=C bonds
5.3.3.1 steroid Delta-isomerase
108528164
BRITE hierarchy
SSDB
Ortholog
Paralog
GFIT
Motif
Pfam:
3Beta_HSD
Epimerase
NAD_binding_4
GDP_Man_Dehyd
Polysacc_synt_2
NAD_binding_10
KR
RmlD_sub_bind
NmrA
Ldh_1_N
Sacchrp_dh_NADP
Semialdhyde_dh
Motif
Other DBs
NCBI-GeneID:
108528164
NCBI-ProteinID:
XP_017725340
UniProt:
A0A2K6L7B4
LinkDB
All DBs
Position
Unknown
AA seq
373 aa
AA seq
DB search
MMGWSCLVTGAGGFLGQRIVRLLVEEKELKEIRVLDKAFRPELREEFSKLQNKTKLTVLE
GDILDEPFLKRACQDISVVIHTACIIDVSGVIHRESIMNVNVKGTQLLLEACVQASVPVF
IYTSSIEVAGPNSYKEIIQNGHEEEPLENTWSAPYPYSKKLAEKAVLAADGWTLKNGGTL
YTCALRPMYIYGEGSQFLSAGINEALNNNGILSSVGKFSTVNPVYVGNVAWAHILALRAL
RDPKKAPSVRGQFYYISDDTPHQSYDNLNYILSKEFGLRLDSRWSLPLSLMYWIGFLLEI
VSFLLRPIYTYQPPFNRHMVTLSNSVFTFSYKKAQRDLAYEPLYSWEEAKQKTVEWVGSL
VDRHKDTLKSKTQ
NT seq
1122 nt
NT seq
+upstream
nt +downstream
nt
atgatgggctggagctgccttgtgacaggagcaggagggtttctgggtcagaggatcgtc
cgcctcttggtggaggagaaggagctgaaggagatcagagtcttggacaaggccttcaga
ccagaactgagggaggaattttccaagctccagaacaagaccaagctgacagtgctggaa
ggagacattctggatgagccattcctgaagagagcctgccaggacatctcagttgtcatc
cacactgcctgtatcattgatgtctccggtgtcattcacagagagtccatcatgaatgtc
aatgtgaaaggtacccagctcctgttagaggcctgtgtccaagctagtgtgccagtcttc
atctataccagtagcatagaggtagccggacccaactcgtacaaggaaatcatccagaac
ggccacgaagaagagcctctggaaaacacatggtctgctccatacccatacagcaaaaag
cttgctgagaaggcagtgctggcagctgatggatggactctgaaaaacggtggcaccttg
tacacttgtgccttaagacccatgtatatctatggggaaggaagccaattcctttctgct
ggtataaatgaagccctgaacaacaatgggatcctgtcaagtgttggcaagttctccact
gtcaacccagtctatgttggcaacgtggcctgggcccacattctggccttgagggccctg
cgggaccccaagaaggccccaagtgtccgaggacagttctactatatctcagatgacacg
cctcaccaaagctatgataaccttaattacatcctgagcaaagagttcggcctccgcctt
gattccagatggagccttcctttatccctgatgtactggattggcttcctgctggaaata
gtgagcttccttctcaggccaatttacacctatcaaccaccctttaaccgccacatggtg
acattgtcaaatagcgtgttcaccttctcttacaagaaggctcagcgagatctggcgtat
gagccgctctacagctgggaggaagccaagcagaaaaccgtggagtgggttggttccctt
gtggaccggcacaaggacaccctgaagtccaagactcagtga
DBGET
integrated database retrieval system
